The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
A unifying hypothesis on mammalian neural stem cell properties in the adult hippocampus
Open accessAbstract
Summary Continuously generated new neurons promote circuitry plasticity within specialized regions and contribute to specific functions of adult mammalian brain. A number of recent studies have investigated the cellular origin of adult neurogenesis in the hippocampus, yielding divergent models of neural stem cell behavior. An essential question remains whether these models are overlapping or fundamentally discrete. We review evidence that primary neural precursors in the adult hippocampus exhibit significant heterogeneity in their properties of self-renewal, multi-lineage differentiation and regulation, representing a range from unipotential committed precursors to bona fide self-renewing multipotent neural stem cells. We further present a testable unifying hypothesis of adult neural stem cell behavior in vivo to outline a common framework for future studies of molecular and cellular mechanisms regulating adult neural stem cells and how these cells may contribute to hippocampal function and repair.
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Cites
Identification of stem cells in small intestine and colon by marker gene Lgr5
Barker, N., van Es, J. H., Kuipers, J., Kujala, P., van den Born, M., Cozijnsen, M., Haegebarth, A., Korving, J., Begthel, H., Peters, P. J., et al. (2007) · Nature · doi:10.1038/nature06196 · Cited by 5,687
Gage, F. H. (2000) · Science · doi:10.1126/science.287.5457.1433 · Cited by 4,786
Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants
Santarelli, L., Saxe, M., Gross, C., Surget, A., Battaglia, F., Dulawa, S., Weisstaub, N., Lee, J., Duman, R., Arancio, O., et al. (2003) · Science · doi:10.1126/science.1083328 · Cited by 4,321
Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions
Ming, G.-L., & Song, H. (2011) · Neuron · doi:10.1016/j.neuron.2011.05.001 · Cited by 2,651
Self-citationWilson, A., Laurenti, E., Oser, G., van der Wath, R. C., Blanco-Bose, W., Jaworski, M., Offner, S., Dunant, C. F., Eshkind, L., Bockamp, E., et al. (2008) · Cell · doi:10.1016/j.cell.2008.10.048 · Cited by 1,908
Astrocytes give rise to new neurons in the adult mammalian hippocampus
Seri, B., Garcı́a-Verdugo, J. M., McEwen, B. S., & Alvarez-Buylla, A. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-18-07153.2001 · Cited by 1,495
Adult hippocampal neurogenesis buffers stress responses and depressive behaviour
Snyder, J. S., Soumier, A., Brewer, M., Pickel, J., & Cameron, H. A. (2011) · Nature · doi:10.1038/nature10287 · Cited by 1,473
Coexistence of Quiescent and Active Adult Stem Cells in Mammals
Li, L., & Clevers, H. (2010) · Science · doi:10.1126/science.1180794 · Cited by 1,247
A Critical Period for Enhanced Synaptic Plasticity in Newly Generated Neurons of the Adult Brain
Ge, S., Yang, C.-H., Hsu, K.-S., Ming, G.-L., & Song, H. (2007) · Neuron · doi:10.1016/j.neuron.2007.05.002 · Cited by 927
Self-citationAimone, J. B., Deng, W., & Gage, F. H. (2011) · Neuron · doi:10.1016/j.neuron.2011.05.010 · Cited by 663 · cited 1×
“Adult hippocampal neurogenesis draws much interest because newborn hippocampal neurons have been suggested to adapt the brain to temporal events in external space, including spatial learning and retention, pattern discrimination and clearance of memory traces [3,4].”
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Cited by
Neurogenesis in the adult hippocampus
Kempermann, G., Song, H., & Gage, F. H. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a018812 · Cited by 1,072
Self-citationRegulation and function of adult neurogenesis: from genes to cognition.
Aimone, J. B., Li, Y., Lee, S. W., Clemenson, G. D., Deng, W., & Gage, F. H. (2014) · Physiological Reviews · doi:10.1152/physrev.00004.2014 · Cited by 635
Adult Neural Stem Cells Bridge Their Niche
Fuentealba, L. C., Obernier, K., & Alvarez-Buylla, A. (2012) · Cell Stem Cell · doi:10.1016/j.stem.2012.05.012 · Cited by 364
Functions and dysfunctions of adult hippocampal neurogenesis
Christian, K. M., Song, H., & Ming, G.-L. (2014) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-071013-014134 · Cited by 362
Self-citationAdult Neurogenesis Is Sustained by Symmetric Self-Renewal and Differentiation
Obernier, K., Cebrian-Silla, A., Thomson, M., Parraguez, J. I., Anderson, R., Guinto, C., Rodas Rodriguez, J., Garcia-Verdugo, J.-M., & Alvarez-Buylla, A. (2018) · Cell Stem Cell · doi:10.1016/j.stem.2018.01.003 · Cited by 250
Metadata
- Authors
- Bonaguidi, M. A., Song, J., Ming, G.-L., & Song, H.
- Venue
- Current Opinion in Neurobiology
- Publisher
- Elsevier BV
- Published
- 2012-10
- Volume
- 22
- Issue
- 5
- Pages
- 754-761
- ISSN
- 0959-4388 (ISSN-L)
- OpenAlex
- W2036397344
- Cited by
- 176
- References
- 14
- FWCI
- 2.13
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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