Specific role of medial prefrontal cortex in retrieving recent autobiographical memories: an fMRI study of young female subjects
Abstract
Episodic-autobiographical memory (AM) is characterized by self-conscious reflection, emotional connotation and mental time travel. Semantic memory (SM) contains context and emotion free general knowledge. The present study specifically aimed at exploring the effect of time on the neural substrates of autobiographical and semantic memory retrieval by studying memories from different life periods in young female participants using functional brain imaging. Recent compared to early childhood events activated retrosplenial cortex. More importantly, medial prefrontal cortex (MPFC) was specifically engaged in the retrieval of recent AMs. The data show time-modulated neural substrates during recent and remote memories in women and suggest that a specific MPFC activation underlies the autonoetic, emotional and self-related character of recent AMs.
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Most prior laboratory-based EM studies used cue words or images to trigger memory retrieval and mental time travel to the past in a controlled fashion.
“Most prior laboratory-based EM studies used cue words or images to trigger memory retrieval and mental time travel to the past in a controlled fashion [5,6,12,31,60,80,87,103–105].”
From First-person view of one’s body in immersive virtual reality: Influence on episodic memory (2019) · cites this paper as [6]
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Dong, S.-Y., Kim, B.-K., & Lee, S.-Y. (2016) · Social Neuroscience · doi:10.1080/17470919.2015.1059362 · Cited by 6 · see citing works
Viard, A., Allen, A. P., Doyle, C., Naveau, M., Bokde, A. L. W., Platel, H., Eustache, F., Commins, S., & Roche, R. A. P. (2023) · Biological Research For Nursing · doi:10.1177/10998004231210982 · Cited by 4 · see citing works
Do shorter Cortex papers have greater impact?
Foley, J. A., & Sala, S. D. (2011) · Cortex · doi:10.1016/j.cortex.2011.03.008 · Cited by 3 · see citing works
Are higher cited papers accepted faster for publication?
Foley, J. A., & Valkonen, L. (2012) · Cortex · doi:10.1016/j.cortex.2012.03.018 · Cited by 2 · see citing works
Proshin, S. N., Glushakov, R. I., Семенова, И. В., Николаевна, В. И., Saikovskaya, L. A., & Игоревна, Т. Н. (2013) · PubMed · Cited by 2 · see citing works
Kumar, G., Naaz, S., Jabin, N., Sasidharan, A., Nagendra, R. P., Yadav, R., & Kutty, B. M. (2025) · Consciousness and Cognition · doi:10.1016/j.concog.2025.103869 · Cited by 1 · see citing works
Autobiographical Memory across the Life Span - Brain Imaging and Neuropsychology
Markowitsch, H. J. (2010) · Conference of the Australasian Society for Cognitive Science · doi:10.5096/ascs200934 · Cited by 1 · see citing works
Self-citationThe neural signature of emotional memories in serial crimes
Chassy, P. (2017) · Medical Hypotheses · doi:10.1016/j.mehy.2017.07.026 · Cited by 1 · see citing works
Processos não-declarativos em tomadas de decisão: modelos e experimentos
Dias, Á. M. (2010) · doi:10.11606/t.47.2010.tde-27072010-081906 · Cited by 1 · see citing works
Non-monotonic recruitment of ventromedial prefrontal cortex during remote memory recallPreprint
Barry, D. N., Chadwick, M. J., & Maguire, E. A. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/202689 · Cited by 1 · see citing works
Viagem mental através do tempo: revisão sistemática
Dias, Á. M. (2013) · Revista Interamericana de Psicología/Interamerican Journal of Psychology · doi:10.30849/rip/ijp.v46i3.294
Semantic Feature Type Constrains the Organization and Computation of Concrete Conceptual Knowledge
Amsel, B. D. (2011) · TSpace (University of Toronto)
Does a paper's country of origin affect the length of the review process?
Valkonen, L., & Lucia, N. D. (2012) · Cortex · doi:10.1016/j.cortex.2012.05.015
Anderson, S. T. (2014) · Maynooth University ePrints and eTheses Archive (Maynooth University)
Current Awareness in NMR in Biomedicine
John Wiley & Sons, L. (2010) · NMR in Biomedicine · doi:10.1002/nbm.1456
- Authors
- Oddo, S., Lux, S., Weiss, P. H., Schwab, A., Welzer, H., Markowitsch, H. J., & Fink, G. R.
- Affiliations
- Bielefeld University (DE)
- Forschungszentrum Jülich (DE)
- Corresponding author
- Markowitsch, Hans J.
- Venue
- Cortex
- Publisher
- Elsevier BV
- Published
- 2010-01
- Volume
- 46
- Issue
- 1
- Pages
- 29-39
- ISSN
- 0010-9452 (ISSN-L)
- OpenAlex
- W2038049449
- Cited by
- 54
- References
- 67
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 3 · 2021: 1 · 2019: 3 · 2018: 4 · 2017: 5 · 2016: 1 · 2015: 2 · 2014: 3 · 2013: 8 · 2012: 8
- FWCI
- 2.24
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Cortex (publishedVersion)
- PubMed (publishedVersion)
- JuSER (Forschungszentrum Jülich) (submittedVersion)
- PUB – Publications at Bielefeld University (Bielefeld University) (submittedVersion)
- Publikationen an der Universität Bielefeld (Universität Bielefeld) (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
- Social Sciences › Psychology › Developmental and Educational Psychology › Identity, Memory, and Therapy
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Keywords
- medial prefrontal cortex, autobiographical memory, semantic memory, memory retrieval, retrosplenial cortex, episodic memory, emotional memory, women
- MeSH terms
- Acoustic Stimulation, Analysis of Variance, Attention, Brain Mapping, Emotions, Female, Humans, Image Processing, Computer-Assisted, Interviews as Topic, Functional Laterality, Magnetic Resonance Imaging, Neuropsychological Tests, Surveys and Questionnaires, Mental Recall, Time Factors, Prefrontal Cortex, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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