Cited by 54Memory Processes and InfluencesIdentity, Memory, and TherapyMemory and Neural Mechanisms

Specific role of medial prefrontal cortex in retrieving recent autobiographical memories: an fMRI study of young female subjects

Oddo, Silvia, Lux, Silke, Weiss, Peter H., Schwab, Anna, Welzer, Harald, Markowitsch, Hans J., Fink, Gereon R.·2010·Cortex

Abstract

Episodic-autobiographical memory (AM) is characterized by self-conscious reflection, emotional connotation and mental time travel. Semantic memory (SM) contains context and emotion free general knowledge. The present study specifically aimed at exploring the effect of time on the neural substrates of autobiographical and semantic memory retrieval by studying memories from different life periods in young female participants using functional brain imaging. Recent compared to early childhood events activated retrosplenial cortex. More importantly, medial prefrontal cortex (MPFC) was specifically engaged in the retrieval of recent AMs. The data show time-modulated neural substrates during recent and remote memories in women and suggest that a specific MPFC activation underlies the autonoetic, emotional and self-related character of recent AMs.

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Crossref · 10.1016/j.cortex.2008.07.003

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  • Most prior laboratory-based EM studies used cue words or images to trigger memory retrieval and mental time travel to the past in a controlled fashion.

    “Most prior laboratory-based EM studies used cue words or images to trigger memory retrieval and mental time travel to the past in a controlled fashion [5,6,12,31,60,80,87,103–105].”

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Authors
Oddo, S., Lux, S., Weiss, P. H., Schwab, A., Welzer, H., Markowitsch, H. J., & Fink, G. R.
Affiliations
  • Bielefeld University (DE)
  • Forschungszentrum Jülich (DE)
Corresponding author
Markowitsch, Hans J.
Venue
Cortex
Publisher
Elsevier BV
Published
2010-01
Volume
46
Issue
1
Pages
29-39
ISSN
0010-9452 (ISSN-L)
OpenAlex
W2038049449
Cited by
54
References
67
Citations by year
2025: 1 · 2024: 1 · 2023: 3 · 2021: 1 · 2019: 3 · 2018: 4 · 2017: 5 · 2016: 1 · 2015: 2 · 2014: 3 · 2013: 8 · 2012: 8
FWCI
2.24
Type
journal article
Language
en
Open access
closed
Locations
  • Cortex (publishedVersion)
  • PubMed (publishedVersion)
  • JuSER (Forschungszentrum Jülich) (submittedVersion)
  • PUB – Publications at Bielefeld University (Bielefeld University) (submittedVersion)
  • Publikationen an der Universität Bielefeld (Universität Bielefeld) (submittedVersion)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
  • Social Sciences › Psychology › Developmental and Educational Psychology › Identity, Memory, and Therapy
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Keywords
medial prefrontal cortex, autobiographical memory, semantic memory, memory retrieval, retrosplenial cortex, episodic memory, emotional memory, women
MeSH terms
Acoustic Stimulation, Analysis of Variance, Attention, Brain Mapping, Emotions, Female, Humans, Image Processing, Computer-Assisted, Interviews as Topic, Functional Laterality, Magnetic Resonance Imaging, Neuropsychological Tests, Surveys and Questionnaires, Mental Recall, Time Factors, Prefrontal Cortex, Young Adult

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