Cue exposure therapy for the treatment of alcohol use disorders: a meta-analytic review

Mellentin, Angelina I.; Skøt, Lotte; Nielsen, Bent; Schippers, Gerard M.; Nielsen, Anette S.; Stenager, Elsebeth; Juhl, Carsten

doi:10.1016/j.cpr.2017.07.006

Cited by 149Substance Abuse Treatment and OutcomesAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesGambling Behavior and Treatments

Cue exposure therapy for the treatment of alcohol use disorders: a meta-analytic review

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Mellentin, Angelina I., Skøt, Lotte, Nielsen, Bent, Schippers, Gerard M., Nielsen, Anette S., Stenager, Elsebeth, Juhl, Carsten·2017·Clinical Psychology Review

DOI 10.1016/j.cpr.2017.07.006

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Abstract

Cue Exposure Therapy (CET) is a behavioristic psychological approach to treating substance use disorders (SUD). Prior systematic reviews have found CET to be ineffective when targeting SUDs. The effect of this approach on alcohol use disorders (AUD) seems more promising at trial level but has yet to be systematically reviewed and quantitatively analyzed. Therefore, we aimed to examine the effectiveness of CET targeting AUD compared to active control conditions in a meta-analytic review. Following a systematic search of the literature, a total of seven controlled trials were identified. CET showed no to small additional effects on drinking intensity and drinking frequency, a small additional effect on total drinking score and a moderate additional effect on latency to relapse. Stratification and analysis of a-priori defined trial covariates revealed that CET may have an increased effect in the longer term, and that CET combined with urge-specific coping skills may be the better option for treating AUD than conventional CET. Also, CET may prove less effective when comparing it to cognitive behaviour therapy as opposed to other active control conditions. The overall quality of evidence was graded low due to high risk of bias, inconsistency, imprecision and suspected publication bias. Sounder methodological trials are needed to derive a firm conclusion about the effectiveness of CET for treating AUD.

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A meta-analysis found that the efficacy of traditional cue exposure therapy in treating alcohol use disorder was limited or even not better than CBT.
“However, a meta-analysis pointed out that the efficacy of traditional CET in the treatment of alcohol use disorder was limited or even not better than CBT (16)”
From The efficacy of virtual reality exposure therapy for the treatment of alcohol use disorder among adult males: a randomized controlled trial comparing with acceptance and commitment therapy and treatment as usual (2023) · cites this paper as [16]

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Authors: Mellentin, A. I., Skøt, L., Nielsen, B., Schippers, G. M., Nielsen, A. S., Stenager, E., & Juhl, C.
Affiliations: University of Southern Denmark (DK)
Amsterdam UMC Location University of Amsterdam (NL)
Corresponding author: Mellentin, Angelina I.
ORCID: Mellentin, Angelina I.
Skøt, Lotte
Nielsen, Bent
Schippers, Gerard M.
Nielsen, Anette S.
Stenager, Elsebeth
Juhl, Carsten
Venue: Clinical Psychology Review
Publisher: Elsevier BV
Published: 2017-11
Volume: 57
Pages: 195-207
ISSN: 0272-7358 (ISSN-L)
DOI: 10.1016/j.cpr.2017.07.006
OpenAlex: W2740457908
Cited by: 149
References: 99
Citations by year: 2026: 8 · 2025: 12 · 2024: 16 · 2023: 29 · 2022: 20 · 2021: 25 · 2020: 15 · 2019: 14 · 2018: 10
FWCI: 1.42
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc-nd
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
creativecommons.org/licenses/by-nc-nd/4.0/ (vor)
Locations: Clinical Psychology Review (publishedVersion, cc-by-nc-nd)
PubMed (publishedVersion)
Data Archiving and Networked Services (DANS) (submittedVersion)
University of Southern Denmark Research Portal (University of Southern Denmark) (submittedVersion, cc-by-nc-nd)
Funders: Lundbeckfonden (R155‐2012‐11282)
Topics: Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Social Sciences › Psychology › Clinical Psychology › Gambling Behavior and Treatments
Keywords: cue exposure therapy, alcoholism, alcohol relapse, drinking intensity, cognitive behavioral therapy, addiction treatment, treatment effectiveness
MeSH terms: Alcoholism, Cues, Humans, Implosive Therapy, Outcome Assessment, Health Care

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Cue exposure therapy for the treatment of alcohol use disorders: a meta-analytic review

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