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Cerebellar rTMS disrupts predictive language processing
Open accessAbstract
The human cerebellum plays an important role in language, amongst other cognitive and motor functions [1], but a unifying theoretical framework about cerebellar language function is lacking. In an established model of motor control, the cerebellum is seen as a predictive machine, making short-term estimations about the outcome of motor commands. This allows for flexible control, on-line correction, and coordination of movements [2]. The homogeneous cytoarchitecture of the cerebellar cortex suggests that similar computations occur throughout the structure, operating on different input signals and with different output targets [3]. Several authors have therefore argued that this ‘motor' model may extend to cerebellar nonmotor functions [3–5], and that the cerebellum may support prediction in language processing [6]. However, this hypothesis has never been directly tested. Here, we used the ‘Visual World' paradigm [7], where on-line processing of spoken sentence content can be assessed by recording the latencies of listeners' eye movements towards objects mentioned. Repetitive transcranial magnetic stimulation (rTMS) was used to disrupt function in the right cerebellum, a region implicated in language [8]. After cerebellar rTMS, listeners showed delayed eye fixations to target objects predicted by sentence content, while there was no effect on eye fixations in sentences without predictable content. The prediction deficit was absent in two control groups. Our findings support the hypothesis that computational operations performed by the cerebellum may support prediction during both motor control and language processing.
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“the cerebellar regions of interest for mood and cognition modulation are relatively superficial (Desmond et al., 2005; Hardwick et al., 2014; Lesage et al., 2012; Theoret et al., 2001)”
From A double-blind, randomized, sham-controlled clinical trial of cerebellar intermittent theta burst stimulation for bipolar disorder: Safety, tolerability, mood and cognitive effects (2025) · cites this paper as Lesage et al., 2012
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Cites
Mixed-effects modeling with crossed random effects for subjects and items
Baayen, R. H., Davidson, D. J., & Bates, D. M. (2008) · Journal of Memory and Language · doi:10.1016/j.jml.2007.12.005 · Cited by 8,540
The organization of the human cerebellum estimated by intrinsic functional connectivity
Buckner, R. L., Krienen, F. M., Castellanos, A., Diaz, J. C., & Yeo, B. T. T. (2011) · Journal of Neurophysiology · doi:10.1152/jn.00339.2011 · Cited by 7,304
The CELEX Lexical Database (CD-ROM)
Baayen, R. H., Piepenbrock, R., & Gulikers, L. (1996) · Max Planck Digital Library · Cited by 2,276
Forward Models for Physiological Motor Control
Miall, R. C., & Wolpert, D. M. (1996) · Neural Networks · doi:10.1016/s0893-6080(96)00035-4 · Cited by 2,260
Self-citationFunctional topography in the human cerebellum: A meta-analysis of neuroimaging studies
STOODLEY, C., & SCHMAHMANN, J. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2008.08.039 · Cited by 2,183
Depression of motor cortex excitability by low-frequency transcranial magnetic stimulation
Chen, R., Classen, J., Gerloff, C., Celnik, P., Wassermann, E. M., Hallett, M., & Cohen, L. G. (1997) · Neurology · doi:10.1212/wnl.48.5.1398 · Cited by 2,128
Cerebellum and nonmotor function
Strick, P. L., Dum, R. P., & Fiez, J. A. (2009) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.31.060407.125606 · Cited by 1,777
Incremental interpretation at verbs: restricting the domain of subsequent reference.
Altmann, G., & Kamide, Y. (1999) · Cognition · doi:10.1016/s0010-0277(99)00059-1 · Cited by 1,615
Cerebellar loops with motor cortex and prefrontal cortex of a nonhuman primate
Kelly, R. M., & Strick, P. L. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-23-08432.2003 · Cited by 1,595
Human Brain Language Areas Identified by Functional Magnetic Resonance Imaging
Binder, J. R., Frost, J. A., Hammeke, T. A., Cox, R. W., Rao, S. M., & Prieto, T. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-01-00353.1997 · Cited by 1,424
The anatomy of language: a review of 100 fMRI studies published in 2009
Price, C. J. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2010.05444.x · Cited by 1,387
Control of mental activities by internal models in the cerebellum
Ito, M. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2332 · Cited by 1,356
The temporal structure of spoken language understanding
Marslen‐Wilson, W. D., & TYLER, L. K. (1980) · Cognition · doi:10.1016/0010-0277(80)90015-3 · Cited by 1,320
Is the cerebellum a Smith predictor?
Miall, R. C., Weir, D. J., Wolpert, D. M., & Stein, J. F. (1993) · Journal of Motor Behavior · doi:10.1080/00222895.1993.9942050 · Cited by 1,071 · cited 3×
“It is thought the cerebellum contributes to fast and flexible motor control by predicting the sensory consequences of movements on a fine timescale, and that these predictions are available before visual or proprioceptive feedback from the executed actions [2,4].”
BackgroundMethodSelf-citationThe primate cortico-cerebellar system: anatomy and function
Ramnani, N. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1953 · Cited by 1,011
O'Reilly, J. X., Beckmann, C. F., Tomassini, V., Ramnani, N., & Johansen-Berg, H. (2010) · Cerebral Cortex · doi:10.1093/cercor/bhp157 · Cited by 738
New method for fMRI investigations of language: defining ROIs functionally in individual subjects
Fedorenko, E., Hsieh, P.-J., Nieto-Castañón, A., Whitfield-Gabrieli, S., & Kanwisher, N. (2010) · Journal of Neurophysiology · doi:10.1152/jn.00032.2010 · Cited by 686
Do people use language production to make predictions during comprehension?
Pickering, M. J., & Garrod, S. (2007) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2006.12.002 · Cited by 633
Functional magnetic resonance imaging of human brain activity in a verbal fluency task
Schlösser, R. G. M., Hutchinson, M., Joseffer, S. S., Rusinek, H., Saarimaki, A., Stevenson, J., Dewey, S. L., & Brodie, J. D. (1998) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.64.4.492 · Cited by 439
Saccadic overhead: Information-processing time with and without saccades
Matin, E., Shao, K. C., & Boff, K. R. (1993) · Perception & Psychophysics · doi:10.3758/bf03206780 · Cited by 437
The role of the basal ganglia and cerebellum in language processing
Booth, J. R., Wood, L., Lu, D., Houk, J. C., & Bitan, T. (2007) · Brain Research · doi:10.1016/j.brainres.2006.11.074 · Cited by 415
McDermott, K. B., Petersen, S. E., Watson, J. M., & Ojemann, J. G. (2003) · Neuropsychologia · doi:10.1016/s0028-3932(02)00162-8 · Cited by 393
Anatomical correlates of dyslexia: frontal and cerebellar findings
Eckert, M. A. (2003) · Brain · doi:10.1093/brain/awg026 · Cited by 352
The cerebellum contributes to linguistic production
Silveri, M. C., Leggio, M. G., & Molinari, M. (1994) · Neurology · doi:10.1212/wnl.44.11.2047 · Cited by 347
Buckner, R. L. (2000) · Brain · doi:10.1093/brain/123.3.620 · Cited by 345
The Lateralized Linguistic Cerebellum: A Review and a New Hypothesis
Mariën, P., Engelborghs, S., Fabbro, F., & Deyn, P. P. D. (2001) · Brain and Language · doi:10.1006/brln.2001.2569 · Cited by 338
Dyslexia, dysgraphia, procedural learning and the cerebellum
Nicolson, R. I., & Fawcett, A. J. (2009) · Cortex · doi:10.1016/j.cortex.2009.08.016 · Cited by 306
Motor and phosphene thresholds: a transcranial magnetic stimulation correlation study
Stewart, L., Walsh, V., & Rothwell, J. C. (2001) · Neuropsychologia · doi:10.1016/s0028-3932(00)00130-5 · Cited by 300
Functional heterogeneity with structural homogeneity: How does the cerebellum operate?
Bloedel, J. R. (1994) · Cambridge University Press eBooks · doi:10.1017/cbo9780511529788.007 · Cited by 250
Seger, C. A., Desmond, J. E., Glover, G. H., & Gabrieli, J. D. E. (2000) · Neuropsychology · doi:10.1037/0894-4105.14.3.361 · Cited by 229
Functional Topography of the Cerebellum in Verbal Working Memory
Marvel, C. L., & Desmond, J. E. (2010) · Neuropsychology Review · doi:10.1007/s11065-010-9137-7 · Cited by 219
Théoret, H., Haque, J., & Pascual‐Leone, Á. (2001) · Neuroscience Letters · doi:10.1016/s0304-3940(01)01860-2 · Cited by 190
Cerebellar involvement in verb generation: an fMRI study
Frings, M., Dimitrova, A., Schorn, C. F., Elles, H.-G., Hein-Kropp, C., Gizewski, E. R., Diener, H. C., & Timmann, D. (2006) · Neuroscience Letters · doi:10.1016/j.neulet.2006.08.058 · Cited by 149
Mariën, P., Saerens, J., Nanhoe, R., Moens, E., Nagels, G., Pickut, B. A., Dierckx, R. A., & Deyn, P. P. D. (1996) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(96)00059-7 · Cited by 132
Language impairments in patients with cerebellar lesions
Fabbro, F., Moretti, R., & Bava, A. (2000) · Journal of Neurolinguistics · doi:10.1016/s0911-6044(00)00010-5 · Cited by 130
Visual and motor cortex excitability: a transcranial magnetic stimulation study
Boroojerdi, B., Meister, I. G., Foltys, H., Sparing, R., Cohen, L. G., & Töpper, R. (2002) · Clinical Neurophysiology · doi:10.1016/s1388-2457(02)00198-0 · Cited by 119
Involvement of the cerebellum in semantic discrimination: An fMRI study
Xiang, H., Lin, C.-Y., Ma, X., Zhang, Z., Bower, J. M., Weng, X., & Gao, J. (2003) · Human Brain Mapping · doi:10.1002/hbm.10095 · Cited by 115
Dien, J., Frishkoff, G. A., Cerbone, A. B., & Tucker, D. M. (2002) · Cognitive Brain Research · doi:10.1016/s0926-6410(02)00147-7 · Cited by 91
A neural instantiation of the motor theory of speech perception
Ivry, R. B., & Justus, T. C. (2001) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)01897-x · Cited by 42
Activation of the posterior cingulate by semantic priming: A co-registered ERP/fMRI study
O’Hare, A. J., Dien, J., Waterson, L. D., & Savage, C. R. (2007) · Brain Research · doi:10.1016/j.brainres.2007.10.095 · Cited by 39
Tieleman, A., Seurinck, R., Deblaere, K., Vandemaele, P., Vingerhoets, G., & Achten, E. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.02.017 · Cited by 28
Lurito (2000) · doi:10.1002/1097-0193(200007)10:3
Bush (1998) · doi:10.1002/(sici)1097-0193(1998)6:4
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An integrated theory of language production and comprehension
Pickering, M. J., & Garrod, S. (2013) · Behavioral and Brain Sciences · doi:10.1017/s0140525x12001495 · Cited by 1,569
The cerebellum: adaptive prediction for movement and cognition
Sokolov, A. A., Miall, R. C., & Ivry, R. B. (2017) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2017.02.005 · Cited by 691
Self-citationThe Theory and Neuroscience of Cerebellar Cognition
Schmahmann, J. D., Guell, X., Stoodley, C. J., & Halko, M. A. (2019) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-070918-050258 · Cited by 587
Neuroimaging of language control in bilinguals: neural adaptation and reserve
Abutalebi, J., & Green, D. W. (2016) · Bilingualism Language and Cognition · doi:10.1017/s1366728916000225 · Cited by 579
Predicting while comprehending language: A theory and review.
Pickering, M. J., & Gambi, C. (2018) · Psychological Bulletin · doi:10.1037/bul0000158 · Cited by 581
Metadata
- Authors
- Lesage, E., Morgan, B. E., Olson, A. C., Meyer, A. S., & Miall, R. C.
- Affiliations
- University of Birmingham (GB)
- Max Planck Society (DE)
- Corresponding author
- Lesage, Elise
- Venue
- Current Biology
- Publisher
- Elsevier BV
- Published
- 2012-09
- Volume
- 22
- Issue
- 18
- Pages
- R794-R795
- ISSN
- 0960-9822 (ISSN-L)
- PMC
- PMC3459089
- OpenAlex
- W2039237595
- Cited by
- 141
- References
- 43
- Citations by year
- 2026: 6 · 2025: 6 · 2024: 7 · 2023: 9 · 2022: 9 · 2021: 18 · 2020: 10 · 2019: 16 · 2018: 6 · 2017: 13 · 2016: 10 · 2015: 11 · 2014: 9 · 2013: 11
- FWCI
- 5.08
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Current Biology (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- MPG.PuRe (Max Planck Society) (submittedVersion, other-oa)
- University of Birmingham Research Portal (University of Birmingham) (submittedVersion, cc-by)
- Funders
- Wellcome Trust (WT087554)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neurobiology of Language and Bilingualism
- Life Sciences › Neuroscience › Neurology › Transcranial Magnetic Stimulation Studies
- Social Sciences › Psychology › Social Psychology › Action Observation and Synchronization
- Keywords
- cerebellum, language processing, predictive processing, repetitive transcranial magnetic stimulation, eye fixations, visual world paradigm, sentence comprehension, motor control models
- MeSH terms
- Cerebellum, Cognition, Fixation, Ocular, Humans, Language, Psychomotor Performance, Speech, Transcranial Magnetic Stimulation
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