The DOI matches its Crossref record; 125 of the 125 references it cites were found in a registry or an index.
The Extracellular Matrix Modulates the Metastatic Journey
Open accessAbstract
The extracellular matrix is perturbed in tumors. The tumor matrix promotes the growth, survival and invasion of the cancer and modifies fibroblast and immune cell behavior to drive metastasis and impair treatment. Here, we discuss how the tumor matrix regulates metastasis by fostering tumor cell invasion into the stroma and migration towards the vasculature. We describe the role of the tumor matrix on cancer cell intravasation and vascular dissemination. We examine the impact of the matrix on disseminated tumor cell extravasation and on tumor dormancy and metastatic outgrowth. Finally, we discuss the clinical outcome of therapeutics that normalize tumor-matrix interactions.
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2 retracted
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Metadata
- Authors
- Kai, F., Drain, A. P., & Weaver, V. M.
- Venue
- Developmental Cell
- Publisher
- Elsevier BV
- Published
- 2019-05
- Volume
- 49
- Issue
- 3
- Pages
- 332-346
- ISSN
- 1534-5807 (ISSN-L)
- OpenAlex
- W2943229766
- Cited by
- 537
- References
- 125
- FWCI
- 22.49
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
