CoChat
Sign Up
Cited by 44Diabetes, Cardiovascular Risks, and LipoproteinsNutritional Studies and DietDiet and metabolism studies

Long-term effects of a reduced fat diet intervention on cardiovascular disease risk factors in individuals with glucose intolerance

Ley, Sarah J, Metcalf, Patricia A, Scragg, Robert K.R, Swinburn, Boyd A·2004·Diabetes Research and Clinical Practice
DOI 10.1016/j.diabres.2003.09.001
Open this paper in CoChat — free account

Abstract

The long-term effects on cardiovascular disease risk factors of a reduced fat (RF), ad libitum diet were compared with usual diet (control, CD) in glucose intolerance individuals. Participants were 136 adults aged > or =40 years with 'glucose intolerance' (2h blood glucose 7-11.0 mmol/l) detected at a Diabetes Survey who completed at 1 year intervention study of reduced fat, ad libitum diet versus usual diet. They were re-assessed at 2, 3 and 5 years. Main outcome measures were blood pressure, serum concentrations of total cholesterol, HDL and LDL cholesterol, total cholesterol:HDL ratio, triglycerides and body weight. The reduced fat diet lowered total cholesterol (P<0.01), LDL cholesterol (P< or =0.05), total cholesterol:HDL ratio (P< or =0.05), body weight (P<0.01) and systolic blood pressure (P< or =0.05) initially and diastolic blood pressure (P<0.01) long-term. No significant changes occurred in HDL cholesterol or triglycerides. In the more compliant 50% of the intervention group, systolic and diastolic blood pressure levels and body weight were lower at 1, 2 and 3 years (P<0.05). It was concluded that a reduced fat ad libitum diet has short-term benefits for cholesterol, body weight and systolic blood pressure and long-term benefits for diastolic blood pressure without significantly effecting HDL cholesterol and triglycerides despite participants regaining their lost weight.

Integrity signals

Registry

Crossref · 10.1016/j.diabres.2003.09.001

Cites

36 of 36 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Related

Authors
Ley, S. J., Metcalf, P. A., Scragg, R. K. R., & Swinburn, B. A.
Affiliations
  • University of Auckland (NZ)
  • Deakin University (AU)
Corresponding author
Metcalf, Patricia A
ORCID
Venue
Diabetes Research and Clinical Practice
Publisher
Elsevier BV
Published
2004-02
Volume
63
Issue
2
Pages
103-112
ISSN
0168-8227 (ISSN-L)
DOI
10.1016/j.diabres.2003.09.001
OpenAlex
W2024534514
Cited by
43
References
36
Citations by year
2026: 2 · 2025: 1 · 2024: 3 · 2023: 1 · 2021: 1 · 2020: 3 · 2018: 5 · 2017: 2 · 2016: 2 · 2015: 3 · 2014: 3 · 2013: 2 · 2012: 5
FWCI
0.61
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Diabetes Research and Clinical Practice (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Heart Foundation of New Zealand
  • Health Research Council of New Zealand
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
  • Health Sciences › Medicine › Physiology › Diet and metabolism studies
Keywords
reduced-fat diet, impaired glucose tolerance, prediabetes, cardiovascular risk factors, blood pressure, cholesterol, LDL cholesterol, HDL cholesterol, triglycerides, body weight, weight regain, ad libitum feeding, older adults
MeSH terms
Blood Pressure, Body Weight, Cardiovascular Diseases, Cholesterol, Diastole, Female, Humans, Cholesterol, HDL, Cholesterol, LDL, Male, Middle Aged, Patient Compliance, Risk Factors, Systole, Triglycerides, Weight Loss, Glucose Intolerance, Diet, Fat-Restricted

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review