Light-induced melatonin suppression: age-related reduction in response to short wavelength light
Abstract
One of the possible causes of disturbed circadian rhythms and sleep in the elderly may be impaired photic input to the circadian clock. Age-related changes in lens density are known to reduce the transmission of short wavelength light, which has been shown to be most effective in suppressing nocturnal melatonin. The aim of the study therefore was to investigate age-related changes in melatonin suppression in response to short and medium wavelength light. Young premenopausal (n=13) and postmenopausal (n=21) women were exposed to 30 min of monochromatic light at two different wavelengths and irradiances (lambda(max) 456 nm: 3.8 and 9.8 microW/cm(2); lambda(max) 548 nm: 28 and 62 microW/cm(2)). Melatonin suppression was compared across light treatments and between age groups. Significantly reduced melatonin suppression was noted in the elderly subjects following exposure to short wavelength (456 nm) light compared to the young subjects. These results are likely to reflect age-related changes in lens density.
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Significantly reduced melatonin suppression was measured in elderly subjects in response to exposure to blue (456 nm) light as compared to the young group.
“Significantly reduced melatonin suppression was measured in the elderly subjects in response to exposure to blue (456 nm) light as compared to the young group.”
From The inner clock-Blue light sets the human rhythm (2019) · cites this paper as [48]
The finding of reduced melatonin suppression in the elderly is suggested to reflect the age-related changes in lens density.
“This finding is suggested to reflect the age‐related changes in lens density.”
From The inner clock-Blue light sets the human rhythm (2019) · cites this paper as [48]
Environmental light can adversely impact sleep.
“There is substantial literature showing that environmental noise228,229 and light230–233 can adversely impact sleep and that neighborhoods that are active at night may directly impact sleep through these.”
From Sleep, Health, and Society (2017) · cites this paper as [233]
Neighborhoods that are active at night may directly impact sleep through environmental noise and light.
“There is substantial literature showing that environmental noise228,229 and light230–233 can adversely impact sleep and that neighborhoods that are active at night may directly impact sleep through these.”
From Sleep, Health, and Society (2017) · cites this paper as [233]
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Cites
Action Spectrum for Melatonin Regulation in Humans: Evidence for a Novel Circadian Photoreceptor
Brainard, G. C., Hanifin, J. P., Greeson, J. M., Byrne, B., Glickman, G., Gerner, E., & Rollag, M. D. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-16-06405.2001 · Cited by 1,930 · see citing works
Thapan, K., Arendt, J., & Skene, D. J. (2001) · The Journal of Physiology · doi:10.1111/j.1469-7793.2001.t01-1-00261.x · Cited by 1,320 · see citing works
Spectral sensitivity of the foveal cone photopigments between 400 and 500 nm
Smith, V. C., & Pokorny, J. (1975) · Vision Research · doi:10.1016/0042-6989(75)90203-5 · Cited by 1,318 · see citing works
Sleep in Normal Aging and Dementia
Bliwise, D. L. (1993) · SLEEP · doi:10.1093/sleep/16.1.40 · Cited by 854 · see citing works
High Sensitivity of the Human Circadian Melatonin Rhythm to Resetting by Short Wavelength Light
Lockley, S. W., Brainard, G. C., & Czeisler, C. A. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-030570 · Cited by 782 · see citing works
Direct radioimmunoassay for melatonin in plasma.
Fraser, S., Cowen, P. J., Franklin, M., Franey, C. S., & Arendt, J. (1983) · Clinical Chemistry · doi:10.1093/clinchem/29.2.396 · Cited by 578 · see citing works
Pokorny, J., Smith, V. C., & Lutze, M. (1987) · Applied Optics · doi:10.1364/ao.26.001437 · Cited by 516 · see citing works
Indirect bright light improves circadian rest-activity rhythm disturbances in demented patients
Someren, E. J. W. V., Kessler, A., Mirmiran, M., & Swaab, D. F. (1997) · Biological Psychiatry · doi:10.1016/s0006-3223(97)89928-3 · Cited by 440 · see citing works
Spectral transmission of the human ocular media
Norren, D. V., & Vos, J. J. (1974) · Vision Research · doi:10.1016/0042-6989(74)90222-3 · Cited by 377 · see citing works
The Variation with Age of the Spectral Transmissivity of the Living Human Crystalline Lens
Said, F., & Weale, R. A. (2009) · Gerontologia · doi:10.1159/000210900 · Cited by 337 · see citing works
Later endogenous circadian temperature nadir relative to an earlier wake time in older people
Duffy, J. F., Dijk, D., Klerman, E. B., & Czeisler, C. A. (1998) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1998.275.5.r1478 · Cited by 318 · see citing works
Exposure to light in healthy elderly subjects and alzheimer's patients
Campbell, S. S., Kripke, D. F., Gillin, J. C., & Hrubovcak, J. C. (1988) · Physiology & Behavior · doi:10.1016/0031-9384(88)90289-2 · Cited by 277 · see citing works
Circadian and sleep disturbances in the elderly
Someren, E. J. W. V. (2000) · Experimental Gerontology · doi:10.1016/s0531-5565(00)00191-1 · Cited by 273 · see citing works
Melatonin rhythmicity: effect of age and Alzheimer's disease
Skene, D. J. (2003) · Experimental Gerontology · doi:10.1016/s0531-5565(02)00198-5 · Cited by 270 · see citing works
Phase advancing human circadian rhythms with short wavelength light
Warman, V. L., Dijk, D., Warman, G. R., Arendt, J., & Skene, D. J. (2003) · Neuroscience Letters · doi:10.1016/s0304-3940(03)00223-4 · Cited by 192 · see citing works
Insomnia in the elderly: a review for the primary care practitioner.
Ancoli‐Israel, S. (2000) · PubMed · Cited by 183 · see citing works
Jedziniak, J. A., Kinoshita, J. H., Yates, E. M., Hocker, L. O., & Benedek, G. B. (1973) · Experimental Eye Research · doi:10.1016/0014-4835(73)90118-8 · Cited by 164 · see citing works
Dijk, D., & Duffy, J. F. (1999) · Annals of Medicine · doi:10.3109/07853899908998789 · Cited by 155 · see citing works
Inducing jet‐lag in older people: Directional asymmetry
Monk, T. H., Buysse, D. J., Carrier, J., & Kupfer, D. J. (2000) · Journal of Sleep Research · doi:10.1046/j.1365-2869.2000.00184.x · Cited by 103 · see citing works
TIME RESOLVED SPECTROSCOPIC STUDIES ON THE INTACT HUMAN LENS
Dillon, J. P., & Atherton, S. J. (1990) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1990.tb01738.x · Cited by 97 · see citing works
Optical density of the human lens
Xu, J., Pokorny, J., & Smith, V. C. (1997) · Journal of the Optical Society of America A · doi:10.1364/josaa.14.000953 · Cited by 93 · see citing works
Disulfide bond formation in the eye lens.
Yu, N., DeNagel, D. C., Pruett, P. L., & Kuck, J. F. R. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.23.7965 · Cited by 85 · see citing works
Garner, B., Vazquez, S., Griffith, R., Lindner, R. A., Carver, J. A., & Truscott, R. J. W. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.30.20847 · Cited by 79 · see citing works
Human lenticular fluorescence and transmissivity, and their effects on vision
Weale, R. A. (1985) · Experimental Eye Research · doi:10.1016/s0014-4835(85)80004-x · Cited by 68 · see citing works
Density of human lens pigmentation:In vivo measures over an extended age range
Coren, S., & Girgus, J. S. (1972) · Vision Research · doi:10.1016/0042-6989(72)90124-1 · Cited by 66 · see citing works
Does bright light suppress nocturnal melatonin secretion more in women than men?
Monteleone, P., Esposito, G., Rocca, A., & Maj, M. (1995) · Journal of Neural Transmission · doi:10.1007/bf01276567 · Cited by 49 · see citing works
Effects of light on melatonin production
Boyce, P. M., & Kennaway, D. J. (1987) · Biological Psychiatry · doi:10.1016/0006-3223(87)90169-7 · Cited by 47 · see citing works
The effect of gender on the melatonin suppression by light: a dose response relationship
Nathan, P. J., Wyndham, E. L., Burrows, G. D., & Norman, T. R. (2000) · Journal of Neural Transmission · doi:10.1007/s007020050022 · Cited by 38 · see citing works
Accleration of an aging parameter (fluorogen) in the ocular lens.
Lerman, S., Kuck, J. F. R., Borkman, R. F., & Saker, E. (1976) · PubMed · Cited by 15 · see citing works
Retinal Irradiation and Aniseikonia
Weale, R. A. (1954) · British Journal of Ophthalmology · doi:10.1136/bjo.38.4.248 · Cited by 13 · see citing works
(1971) · PubMed · Cited by 13 · see citing works
The effect of age and pre-light melatonin concentration on the melatonin sensitivity to dim light
Nathan, P. J., Burrows, G. D., & Norman, T. R. (1999) · International Clinical Psychopharmacology · doi:10.1097/00004850-199905030-00008 · Cited by 13 · see citing works
The effect of age and pre-light melatonin concentration on the melatonin sensitivity to dim light
Nathan, P. J., Burrows, G. D., & Norman, T. R. (1999) · International Clinical Psychopharmacology · doi:10.1097/00004850-199905002-00008 · Cited by 12 · see citing works
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Grandner, M. A. (2017) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2016.10.012 · Cited by 720 · see citing works
Haus, E. L., & Smolensky, M. H. (2013) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2012.08.003 · Cited by 499 · see citing works
Evidence‐Based Recommendations for the Assessment and Management of Sleep Disorders in Older Persons
Bloom, H. G., Ahmed, I., Alessi, C. A., Ancoli‐Israel, S., Buysse, D. J., Kryger, M. H., Phillips, B. A., Thorpy, M. J., Vitiello, M. V., & Zee, P. C. (2009) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2009.02220.x · Cited by 464 · see citing works
The effects of light therapy on sleep problems: A systematic review and meta-analysis
van Maanen, A., Meijer, A. M., van der Heijden, K. B., & Oort, F. J. (2015) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2015.08.009 · Cited by 372 · see citing works
Duffy, J. F., Zitting, K.-M., & Chinoy, E. D. (2015) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2015.08.002 · Cited by 367 · see citing works
Circadian photoreception: ageing and the eye's important role in systemic health
Turner, P. L., & Mainster, M. A. (2008) · British Journal of Ophthalmology · doi:10.1136/bjo.2008.141747 · Cited by 315 · see citing works
The inner clock-Blue light sets the human rhythm
Wahl, S., Engelhardt, M., Schaupp, P., Lappe, C., & Ivanov, I. V. (2019) · Journal of Biophotonics · doi:10.1002/jbio.201900102 · Cited by 293 · see citing works
Age‐related Changes in the Circadian and Homeostatic Regulation of Human Sleep
Cajochen, C., Münch, M., Knoblauch, V., Blatter, K., & Wirz‐Justice, A. (2006) · Chronobiology International · doi:10.1080/07420520500545813 · Cited by 285 · see citing works
Wu, Y., & Swaab, D. F. (2007) · Sleep Medicine · doi:10.1016/j.sleep.2006.11.010 · Cited by 280 · see citing works
Sensitivity of the Human Circadian System to Short-Wavelength (420-nm) Light
Brainard, G. C., Sliney, D., Hanifin, J. P., Glickman, G., Byrne, B., Greeson, J. M., Jasser, S., Gerner, E., & Rollag, M. D. (2008) · Journal of Biological Rhythms · doi:10.1177/0748730408323089 · Cited by 260 · see citing works
Violet and blue light blocking intraocular lenses: photoprotection versus photoreception
Mainster, M. A. (2006) · British Journal of Ophthalmology · doi:10.1136/bjo.2005.086553 · Cited by 236 · see citing works
Vetter, C., Pattison, P. M., Houser, K. W., Herf, M., Phillips, A. J. K., Wright, K. P., Skene, D. J., Brainard, G. C., Boivin, D. B., & Glickman, G. L. (2021) · LEUKOS The Journal of the Illuminating Engineering Society of North America · doi:10.1080/15502724.2021.1872383 · Cited by 226 · see citing works
Light Pollution, Circadian Photoreception, and Melatonin in Vertebrates
Grubisić, M., Haim, A., Bhusal, P., Dominoni, D. M., Gabriel, K. M. A., Jechow, A., Kupprat, F., Lerner, A., Marchant, P., Riley, W. D., et al. (2019) · Sustainability · doi:10.3390/su11226400 · Cited by 224 · see citing works
Influence of light at night on melatonin suppression in children
Higuchi, S., Nagafuchi, Y., Lee, S.-I., & Harada, T. (2014) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2014-1629 · Cited by 200 · see citing works
Demographic factors, fatigue, and driving accidents: An examination of the published literature
Milia, L. V. D., Smolensky, M. H., Costa, G., Howarth, H. D., Ohayon, M. M., & Philip, P. (2010) · Accident Analysis & Prevention · doi:10.1016/j.aap.2009.12.018 · Cited by 195 · see citing works
The role of environmental light in sleep and health: Effects of ocular aging and cataract surgery
Turner, P. L., Someren, E. J. W. V., & Mainster, M. A. (2010) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2009.11.002 · Cited by 187 · see citing works
Melatonin as a biomarker of circadian dysregulation
Mirick, D. K., & Davis, S. (2008) · Cancer Epidemiology, Biomarkers & Prevention · doi:10.1158/1055-9965.epi-08-0605 · Cited by 176 · see citing works
Grandner, M. A. (2022) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2022.03.001 · Cited by 179 · see citing works
Individual differences in light sensitivity affect sleep and circadian rhythms
Chellappa, S. L. (2021) · Sleep · doi:10.1093/sleep/zsaa214 · Cited by 163 · see citing works
Artigas, J. M. G., Felipe, A., Návea, A., Fandiño, A., & Artigas, C. (2012) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.12-9471 · Cited by 154 · see citing works
Post-illumination Pupil Response in Subjects without Ocular Disease
Kankipati, L., Girkin, C. A., & Gamlin, P. D. (2010) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.09-4717 · Cited by 146 · see citing works
Light Exposure Patterns in Healthy Older and Young Adults
Scheuermaier, K. D., Laffan, A. M., & Duffy, J. F. (2010) · Journal of Biological Rhythms · doi:10.1177/0748730410361916 · Cited by 137 · see citing works
Grandner, M. A. (2020) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2020.02.017 · Cited by 139 · see citing works
Age-Related Changes in Acute and Phase-Advancing Responses to Monochromatic Light
Sletten, T. L., Revell, V. L., Middleton, B., Lederle, K. A., & Skene, D. J. (2009) · Journal of Biological Rhythms · doi:10.1177/0748730408328973 · Cited by 137 · see citing works
Self-citationHossain, M. F., Uddin, M. S., Uddin, G. M. S., Sumsuzzman, D. M., Islam, M. S., Barreto, G. E., Mathew, B., & Ashraf, G. M. (2019) · Molecular Neurobiology · doi:10.1007/s12035-019-01660-3 · Cited by 135 · see citing works
Decreased sensitivity to phase-delaying effects of moderate intensity light in older subjects
Duffy, J. F., Zeitzer, J. M., & Czeisler, C. A. (2006) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2006.03.005 · Cited by 135 · see citing works
Aging of Non-Visual Spectral Sensitivity to Light in Humans: Compensatory Mechanisms?
Najjar, R. P., Chiquet, C., Teikari, P., Cornut, P., Claustrat, B., Denis, P., Cooper, H. M., & Gronfier, C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0085837 · Cited by 125 · see citing works
Daily rhythms of the sleep-wake cycle
Waterhouse, J. M., Fukuda, Y., & Morita, T. (2012) · Journal of PHYSIOLOGICAL ANTHROPOLOGY · doi:10.1186/1880-6805-31-5 · Cited by 116 · see citing works
Light‐Induced Melatonin Suppression in Humans with Polychromatic and Monochromatic Light
Revell, V. L., & Skene, D. J. (2007) · Chronobiology International · doi:10.1080/07420520701800652 · Cited by 113 · see citing works
Blue-blocking IOLs Decrease Photoreception Without Providing Significant Photoprotection
Mainster, M. A., & Turner, P. L. (2009) · Survey of Ophthalmology · doi:10.1016/j.survophthal.2009.07.006 · Cited by 109 · see citing works
Ultraviolet Phototoxicity to the Retina
Glickman, R. D. (2011) · Eye & Contact Lens Science & Clinical Practice · doi:10.1097/icl.0b013e31821e45a9 · Cited by 105 · see citing works
Circadian Rhythm Sleep–Wake Disorders in Older Adults
Kim, J. H., Elkhadem, A. R., & Duffy, J. F. (2022) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2022.02.003 · Cited by 106 · see citing works
Light at Night and Breast Cancer Risk Among California Teachers
Hurley, S. E., Goldberg, D. E., Nelson, D. O., Hertz, A., Horn‐Ross, P. L., Bernstein, L., & Reynolds, P. (2014) · Epidemiology · doi:10.1097/ede.0000000000000137 · Cited by 100 · see citing works
Kessel, L., Siganos, G., Jørgensen, T., & Larsen, M. (2011) · SLEEP · doi:10.5665/sleep.1242 · Cited by 100 · see citing works
Seasonality of brain function: role in psychiatric disorders
Zhang, R., & Volkow, N. D. (2023) · Translational Psychiatry · doi:10.1038/s41398-023-02365-x · Cited by 95 · see citing works
Circadian Rhythm Sleep-Wake Disorders in Older Adults
Kim, J. H., & Duffy, J. F. (2017) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2017.09.004 · Cited by 93 · see citing works
Lee, S., Matsumori, K., Nishimura, K., Nishimura, Y., Ikeda, Y., Eto, T., & Higuchi, S. (2018) · Physiological Reports · doi:10.14814/phy2.13942 · Cited by 89 · see citing works
Peña-García, A. (2018) · Tunnelling and Underground Space Technology · doi:10.1016/j.tust.2018.06.005 · Cited by 89 · see citing works
Sleep in Normal Aging, Homeostatic and Circadian Regulation and Vulnerability to Sleep Deprivation
Taillard, J., Gronfier, C., Bioulac, S., Philip, P., & Sagaspe, P. (2021) · Brain Sciences · doi:10.3390/brainsci11081003 · Cited by 86 · see citing works
Light-sensitive brain pathways and aging
Daneault, V., Dumont, M., Massé, É., Vandewalle, G., & Carrier, J. (2016) · Journal of PHYSIOLOGICAL ANTHROPOLOGY · doi:10.1186/s40101-016-0091-9 · Cited by 83 · see citing works
On the Origin and the Consequences of Circadian Abnormalities in Patients With Cirrhosis
Montagnese, S., Middleton, B., Mani, A. R., Skene, D. J., & Morgan, M. Y. (2010) · The American Journal of Gastroenterology · doi:10.1038/ajg.2010.86 · Cited by 82 · see citing works
Light and chronobiology: implications for health and disease
Münch, M. Y., & Bromundt, V. (2012) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2012.14.4/mmuench · Cited by 82 · see citing works
Lai, K. Y., Sarkar, C., Ni, M. Y., Gallacher, J., & Webster, C. J. (2020) · Environmental Research · doi:10.1016/j.envres.2020.109637 · Cited by 78 · see citing works
Light at night and risk of breast cancer: a systematic review and dose–response meta-analysis
Urbano, T., Vinceti, M., Wise, L. A., & Filippini, T. (2021) · International Journal of Health Geographics · doi:10.1186/s12942-021-00297-7 · Cited by 77 · see citing works
Wahnschaffe, A., Haedel, S., Rodenbeck, A., Stoll, C., Rudolph, H., Kozakov, R., Schoepp, H., & Kunz, D. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms14022573 · Cited by 76 · see citing works
Sensitivity of the circadian system to evening bright light in preschool-age children
Akacem, L. D., Wright, K. P., & LeBourgeois, M. K. (2018) · Physiological Reports · doi:10.14814/phy2.13617 · Cited by 70 · see citing works
van Maanen, A., Meijer, A. M., Smits, M. G., van der Heijden, K. B., & Oort, F. J. (2017) · SLEEP · doi:10.1093/sleep/zsw038 · Cited by 67 · see citing works
Responsiveness of the aging circadian clock to light
Benloucif, S., Green, K., L’Hermite‐Balériaux, M., Weıntraub, S., Wolfe, L. F., & Zee, P. C. (2005) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2005.10.011 · Cited by 69 · see citing works
Giménez, M. C., Stefani, O., Cajochen, C., Lang, D., Deuring, G., & Schlangen, L. J. M. (2022) · Journal of Pineal Research · doi:10.1111/jpi.12786 · Cited by 66 · see citing works
Jin, E., Liujun, J., Li, J., Yang, G., Wang, Z., Cao, J., & Chen, Y. (2011) · The Anatomical Record · doi:10.1002/ar.21408 · Cited by 63 · see citing works
Gordijn, M. C. M., 't Mannetje, D., & Meesters, Y. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.08.016 · Cited by 63 · see citing works
Kozaki, T., Kubokawa, A., Taketomi, R., & Hatae, K. (2016) · Neuroscience Letters · doi:10.1016/j.neulet.2015.12.063 · Cited by 60 · see citing works
Aging Reduces the Stimulating Effect of Blue Light on Cognitive Brain Functions
Daneault, V., Hébert, M., Albouy, G., Doyon, J., Dumont, M., Carrier, J., & Vandewalle, G. (2014) · SLEEP · doi:10.5665/sleep.3314 · Cited by 59 · see citing works
Hopkins, S., Morgan, P. L., Schlangen, L. J. M., Williams, P., Skene, D. J., & Middleton, B. (2017) · Current Alzheimer Research · doi:10.2174/1567205014666170608091119 · Cited by 58 · see citing works
Revell, V. L., Barrett, D. C. G., Schlangen, L. J. M., & Skene, D. J. (2010) · Chronobiology International · doi:10.3109/07420528.2010.516048 · Cited by 57 · see citing works
Münch, M. Y., Scheuermaier, K. D., Zhang, R., Dunne, S. P., Guzik, A. M., Silva, E. J., Ronda, J. M., & Duffy, J. F. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.05.029 · Cited by 58 · see citing works
Blue-Blocking IOLs: A Complete Review of the Literature
Henderson, B. A., & Grimes, K. J. (2009) · Survey of Ophthalmology · doi:10.1016/j.survophthal.2009.07.007 · Cited by 58 · see citing works
Does Pupil Constriction under Blue and Green Monochromatic Light Exposure Change with Age?
Daneault, V., Vandewalle, G., Hébert, M., Teikari, P., Mure, L. S., Doyon, J., Gronfier, C., Cooper, H. M., Dumont, M., & Carrier, J. (2012) · Journal of Biological Rhythms · doi:10.1177/0748730412441172 · Cited by 59 · see citing works
Pupillary responses to short-wavelength light are preserved in aging
Rukmini, A. V., Miléa, D., Aung, T., & Gooley, J. J. (2017) · Scientific Reports · doi:10.1038/srep43832 · Cited by 54 · see citing works
Kozaki, T., Kubokawa, A., Taketomi, R., & Hatae, K. (2015) · Journal of PHYSIOLOGICAL ANTHROPOLOGY · doi:10.1186/s40101-015-0067-1 · Cited by 53 · see citing works
Moderie, C., der Maren, S. V., & Dumont, M. (2017) · Sleep Medicine · doi:10.1016/j.sleep.2017.03.021 · Cited by 51 · see citing works
Gürsoy, A. Y., Kiseli, M., & Çağlar, G. S. (2015) · Climacteric · doi:10.3109/13697137.2015.1052393 · Cited by 50 · see citing works
Mainster, M. A., & Turner, P. L. (2011) · Ophthalmology · doi:10.1016/j.ophtha.2010.11.016 · Cited by 50 · see citing works
Phase‐shifting response to light in older adults
Kim, S.-J., Benloucif, S., Reid, K. J., Weıntraub, S., Kennedy, N. L., Wolfe, L. F., & Zee, P. C. (2013) · The Journal of Physiology · doi:10.1113/jphysiol.2013.262899 · Cited by 48 · see citing works
Sleep physiology and disorders in aging and dementia
Benca, R. M., & Teodorescu, M. C. (2019) · Handbook of clinical neurology · doi:10.1016/b978-0-12-804766-8.00026-1 · Cited by 45 · see citing works
Brøndsted, A. E., Lundeman, J. H., & Kessel, L. (2011) · Acta Ophthalmologica · doi:10.1111/j.1755-3768.2011.02291.x · Cited by 44 · see citing works
Höhn, C., Hahn, M. A., Gruber, G., Pletzer, B. A., Cajochen, C., & Hoedlmoser, K. (2024) · Brain Communications · doi:10.1093/braincomms/fcae173 · Cited by 45 · see citing works
Thorne, H. C., Hampton, S. M., Morgan, L., Skene, D. J., & Arendt, J. (2008) · Chronobiology International · doi:10.1080/07420520802106850 · Cited by 41 · see citing works
Eto, T., Ohashi, M., Nagata, K., Shin, N., Motomura, Y., & Higuchi, S. (2021) · Ophthalmic and Physiological Optics · doi:10.1111/opo.12809 · Cited by 41 · see citing works
Giménez, M. C., Beersma, D. G. M., Bollen, P. P., van der Linden, M. L., & Gordijn, M. C. M. (2014) · Chronobiology International · doi:10.3109/07420528.2014.893242 · Cited by 41 · see citing works
Eto, T., & Higuchi, S. (2023) · Journal of PHYSIOLOGICAL ANTHROPOLOGY · doi:10.1186/s40101-023-00328-1 · Cited by 37 · see citing works
Daneault, V., Dumont, M., Massé, É., Forcier, P., Boré, A., Lina, J., Doyon, J., Vandewalle, G., & Carrier, J. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.01557 · Cited by 37 · see citing works
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Schmoll, C., Lascaratos, G., Dhillon, B., Skene, D. J., & Riha, R. L. (2010) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2010.06.001 · Cited by 39 · see citing works
Kervezee, L., Cuesta, M., Cermakian, N., & Boivin, D. B. (2019) · Journal of Biological Rhythms · doi:10.1177/0748730418821776 · Cited by 31 · see citing works
Figueiro, M. G. (2013) · Journal of Carcinogenesis & Mutagenesis · doi:10.4172/2157-2518.1000150 · Cited by 34 · see citing works
Nie, J., Chen, Z., Jiao, F., Zhan, J., Chen, Y., Pan, Z., Deng, C., Xi, X., Kang, X., Wang, Y., et al. (2021) · Optics & Laser Technology · doi:10.1016/j.optlastec.2021.107463 · Cited by 32 · see citing works
Benke, K. K., & Benke, K. (2012) · Human and Ecological Risk Assessment An International Journal · doi:10.1080/10807039.2012.702608 · Cited by 34 · see citing works
A review of the effects of colour and light on non‐image function in humans
Westland, S., Pan, Q., & Lee, S. (2017) · Coloration Technology · doi:10.1111/cote.12289 · Cited by 32 · see citing works
Cheng, D. C., Ganner, J. L., Gordon, C. J., Phillips, C. L., Grunstein, R. R., & Comas, M. (2021) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2021.101491 · Cited by 32 · see citing works
Heterochromatic Flicker Photometry for Objective Lens Density Quantification
Najjar, R. P., Teikari, P., Cornut, P., Knoblauch, K., Cooper, H. M., & Gronfier, C. (2016) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.15-18642 · Cited by 32 · see citing works
Nie, J., Zou, Q., Chen, L., Chen, Z., Hu, Q., Jiao, F., Pan, Z., Deng, C., Zhang, H., Dong, B., et al. (2024) · Building and Environment · doi:10.1016/j.buildenv.2024.111221 · Cited by 30 · see citing works
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Ackermann, K., Sletten, T. L., Ackermann, K., Sletten, T. L., Revell, V. L., Archer, S. N., & Skene, D. J. (2009) · Chronobiology International · doi:10.1080/07420520902929045 · Cited by 29 · see citing works
Li, X., Kelly, D., Nolan, J. M., Dennison, J. L., & Beatty, S. (2016) · Eye · doi:10.1038/eye.2016.266 · Cited by 30 · see citing works
Impact of age on human non-visual responses to light
REVELL, V. L., & SKENE, D. J. (2010) · Sleep and Biological Rhythms · doi:10.1111/j.1479-8425.2009.00418.x · Cited by 31 · see citing works
Age-related neuroendocrine and alerting responses to light
Chellappa, S. L., Bromundt, V., Frey, S., & Cajochen, C. (2021) · GeroScience · doi:10.1007/s11357-021-00333-1 · Cited by 27 · see citing works
The effect of lens aging and cataract surgery on circadian rhythm
Yan, S.-S., & Wang, W. (2016) · International Journal of Ophthalmology · doi:10.18240/ijo.2016.07.21 · Cited by 26 · see citing works
AGE-DEPENDENT ALTERATIONS IN HUMAN PER2 LEVELS AFTER EARLY MORNING BLUE LIGHT EXPOSURE
Jud, C., Chappuis, S., Revell, V. L., Sletten, T. L., Saaltink, D., Cajochen, C., Skene, D. J., & Albrecht, U. (2009) · Chronobiology International · doi:10.3109/07420520903385564 · Cited by 27 · see citing works
Burns, A. C., Phillips, A. J. K., Rutter, M. K., Saxena, R., Cain, S. W., & Lane, J. M. (2022) · SLEEP · doi:10.1093/sleep/zsac287 · Cited by 25 · see citing works
Swope, C. B., Rong, S., Campanella, C., Vaicekonyte, R., Phillips, A. J. K., Cain, S. W., & McGlashan, E. M. (2023) · Chronobiology International · doi:10.1080/07420528.2023.2188091 · Cited by 30 · see citing works
Münch, M. Y., Ladaique, M., Roemer, S., Hashemi, K. K., & Kawasaki, A. (2017) · Frontiers in Neurology · doi:10.3389/fneur.2017.00464 · Cited by 25 · see citing works
The circadian activity rhythm is reset by nanowatt pulses of ultraviolet light
Negelspach, D., Kaladchibachi, S., & Fernandez, F. (2018) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2018.1288 · Cited by 24 · see citing works
Effect of cataract surgery on regulation of circadian rhythms
Erichsen, J. H., Brφndsted, A. E., & Kessel, L. (2015) · Journal of Cataract & Refractive Surgery · doi:10.1016/j.jcrs.2015.09.009 · Cited by 24 · see citing works
Exploring the Impact of Natural Light Exposure on Sleep of Healthy Older Adults: A Field Study
Aarts, M. M., Stapel, J. C., Schoutens, T. A. M. C., & van Hoof, J. (2018) · Journal of Daylighting · doi:10.15627/jd.2018.2 · Cited by 23 · see citing works
Effects of Different Light Intensities in the Morning on Dim Light Melatonin Onset
Kozaki, T., Toda, N., Noguchi, H., & Yasukouchi, A. (2011) · Journal of PHYSIOLOGICAL ANTHROPOLOGY · doi:10.2114/jpa2.30.97 · Cited by 23 · see citing works
Griepentrog, J. E., Zhang, X., Lewis, A., Gianfrate, G., Labiner, H. E., Zou, B., Xiong, Z., Lee, J. S., & Rosengart, M. R. (2019) · Journal of Leukocyte Biology · doi:10.1002/jlb.4hi0519-155r · Cited by 21 · see citing works
Giménez, M. C., Kanis, M. J., Beersma, D. G. M., van der Pol, B. A. E., Norren, D. V., & Gordijn, M. C. M. (2010) · Journal of Biological Rhythms · doi:10.1177/0748730409360888 · Cited by 20 · see citing works
Measurement of Circadian Effectiveness in Lighting for Office Applications
Babilon, S., Beck, S., Kunkel, J., Klabes, J., Myland, P., Benkner, S., & Khanh, T. Q. (2021) · Applied Sciences · doi:10.3390/app11156936 · Cited by 19 · see citing works
Noor, M. C., Revell, V. L., Saradj, F. M., & Yazdanfar, S.-A. (2023) · Brain Research · doi:10.1016/j.brainres.2023.148470 · Cited by 17 · see citing works
Melatonin suppression by light involves different retinal photoreceptors in young and older adults
Najjar, R. P., Prayag, A. S., & Gronfier, C. (2024) · Journal of Pineal Research · doi:10.1111/jpi.12930 · Cited by 18 · see citing works
Eto, T., Teikari, P., Najjar, R. P., Nishimura, Y., Motomura, Y., Kuze, M., & Higuchi, S. (2020) · Scientific Reports · doi:10.1038/s41598-020-73541-y · Cited by 17 · see citing works
- Authors
- HERLJEVIC, M., MIDDLETON, B., THAPAN, K., & SKENE, D.
- Affiliations
- University of Surrey (GB)
- Corresponding author
- SKENE, D
- ORCID
- Venue
- Experimental Gerontology
- Publisher
- Elsevier BV
- Published
- 2005-03
- Volume
- 40
- Issue
- 3
- Pages
- 237-242
- ISSN
- 0531-5565 (ISSN-L)
- OpenAlex
- W2050381923
- Cited by
- 169
- References
- 32
- Citations by year
- 2026: 8 · 2025: 7 · 2024: 8 · 2023: 5 · 2022: 8 · 2021: 12 · 2020: 5 · 2019: 8 · 2018: 7 · 2017: 11 · 2016: 10 · 2015: 5 · 2014: 9 · 2013: 6 · 2012: 8
- FWCI
- 2.08
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Experimental Gerontology (publishedVersion)
- PubMed (publishedVersion)
- Surrey Research Insight Open Access (The University of Surrey) (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
- Physical Sciences › Environmental Science › Global and Planetary Change › Impact of Light on Environment and Health
- Keywords
- melatonin suppression, short-wavelength light, circadian rhythm, aging, lens density, postmenopausal women, sleep disorders, light irradiance, nocturnal melatonin
- MeSH terms
- Adult, Female, Humans, Melatonin, Middle Aged, Radiation, Postmenopause, Area Under Curve
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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