The effect of focal brain injury on beta-amyloid plaque deposition, inflammation and synapses in the APP/PS1 mouse model of Alzheimer’s disease

Amyloid deposition as the central event in the aetiology of Alzheimer’s disease

Hardy, J., & Allsop, D. (1991) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(91)90609-v · Cited by 2,538 · see citing works

Bone Marrow-Derived Microglia Play a Critical Role in Restricting Senile Plaque Formation in Alzheimer's Disease

Simard, A. R., Soulet, D., Gowing, G., Julien, J.-P., & Rivest, S. (2006) · Neuron · doi:10.1016/j.neuron.2006.01.022 · Cited by 1,265 · see citing works

Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease

Meyer-Luehmann, M., Spires-Jones, T. L., Prada, C., Garcia-Alloza, M., de Calignon, A., Rozkalne, A., Koenigsknecht-Talboo, J., Holtzman, D. M., Bacskai, B. J., & Hyman, B. T. (2008) · Nature · doi:10.1038/nature06616 · Cited by 987 · see citing works

Adult mouse astrocytes degrade amyloid-β in vitro and in situ

Wyss-Coray, T., Loike, J. D., Brionne, T. C., Lu, E., Anankov, R., Yan, F., Silverstein, S. C., & Husemann, J. (2003) · Nature Medicine · doi:10.1038/nm838 · Cited by 909 · see citing works

Documented head injury in early adulthood and risk of Alzheimer’s disease and other dementias

Plassman, B. L., Havlik, R. J., Steffens, D. C., Helms, M. J., Newman, T. N., Drosdick, D., Phillips, C., Gau, B. A., Welsh–Bohmer, K. A., Burke, J. R., et al. (2000) · Neurology · doi:10.1212/wnl.55.8.1158 · Cited by 896 · see citing works

Co-expression of multiple transgenes in mouse CNS: a comparison of strategies

Jankowsky, J. L., Slunt, H. H., Ratovitski, T., Jenkins, N. A., Copeland, N. G., & Borchelt, D. (2001) · Biomolecular Engineering · doi:10.1016/s1389-0344(01)00067-3 · Cited by 819 · see citing works

Head injury as a risk factor for Alzheimer's disease: the evidence 10 years on; a partial replication

Fleminger, S. (2003) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.74.7.857 · Cited by 719 · see citing works

Neuroinflammation after traumatic brain injury: Opportunities for therapeutic intervention

Kumar, A., & Loane, D. J. (2012) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2012.06.008 · Cited by 684 · see citing works

Widespread tau and amyloid-beta pathology many years after a single traumatic brain injury in humans

Johnson, V. E., Stewart, W., & Smith, D. H. (2012) · Brain Pathology · doi:10.1111/j.1750-3639.2011.00513.x · Cited by 620 · see citing works

Head Trauma as a Risk Factor for Alzheimer's Disease: A Collaborative Re-Analysis of Case-Control Studies

Mortimer, J. A., Van Duijn, C. M., Chandra, V, Fratiglioni, L., Graves, A. B., Heyman, A., Jorm, A. F., Kokmen, E., Kondo, K., Rocca, W. A., et al. (1991) · International Journal of Epidemiology · doi:10.1093/ije/20.supplement_2.s28 · Cited by 594 · cited 1× · see citing works

Traumatic brain injury and amyloid-β pathology: a link to Alzheimer's disease?

Johnson, V. E., Stewart, W., & Smith, D. H. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2808 · Cited by 587 · see citing works

β-Amyloid precursor protein (βAPP) as a marker for axonal injury after head injury

Gentleman, S. M., Nash, M. J., Sweeting, C. J., Graham, D. I., & Roberts, G. W. (1993) · Neuroscience Letters · doi:10.1016/0304-3940(93)90398-5 · Cited by 570 · see citing works

Beta amyloid protein deposition in the brain after severe head injury: implications for the pathogenesis of Alzheimer's disease.

Roberts, G. W., Gentleman, S. M., Lynch, A., Murray, L., Landon, M., & Graham, D. I. (1994) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.57.4.419 · Cited by 569 · see citing works

Head injury and the risk of AD in the MIRAGE study

Guo, Z., Cupples, L. A., Kurz, A., Auerbach, S. H., Volicer, L., Chui, H., Green, R. C., Sadovnick, A. D., Duara, R., DeCarli, C., et al. (2000) · Neurology · doi:10.1212/wnl.54.6.1316 · Cited by 506 · see citing works

Contribution of glial cells to the development of amyloid plaques in Alzheimer’s disease

Nagele, R. G., Węgiel, J., Venkataraman, V., Imaki, H., Wang, K.-C., & Wegiel, J. (2004) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2004.01.007 · Cited by 497 · see citing works

Astrocytes in Alzheimer's Disease

Verkhratsky, A., Olabarria, M., Noristani, H. N., Yeh, C., & Rodriguez, J. J. (2010) · Neurotherapeutics · doi:10.1016/j.nurt.2010.05.017 · Cited by 453 · see citing works

βA4 amyloid protein deposition in brain after head trauma

Roberts, G., Gentleman, S., Lynch, A., & Graham, D. I. (1991) · The Lancet · doi:10.1016/0140-6736(91)92724-g · Cited by 440 · see citing works

Alzheimer's pathology in human temporal cortex surgically excised after severe brain injury

Ikonomovic, M. D., Uryu, K., Abrahamson, E. E., Ciallella, J. R., Trojanowski, J. Q., Lee, V. M.-Y., Clark, R. S., Marion, D. W., Wisniewski, S. R., & DeKosky, S. T. (2004) · Experimental Neurology · doi:10.1016/j.expneurol.2004.06.011 · Cited by 399 · see citing works

Repetitive Mild Brain Trauma Accelerates Aβ Deposition, Lipid Peroxidation, and Cognitive Impairment in a Transgenic Mouse Model of Alzheimer Amyloidosis

Uryu, K., Laurer, H., McIntosh, T., Praticò, D., Martinez, D., Leight, S., Lee, V. M.-Y., & Trojanowski, J. Q. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-02-00446.2002 · Cited by 337 · see citing works

Microglia and Alzheimer's disease pathogenesis

Streit, W. J. (2004) · Journal of Neuroscience Research · doi:10.1002/jnr.20093 · Cited by 335 · see citing works

Comparative evaluation of synaptophysin-based methods for quantification of synapses

Calhoun, M. E., Jucker, M., Martin, L. J., Thinakaran, G., Price, D. L., & Mouton, P. R. (1996) · Journal of Neurocytology · doi:10.1007/bf02284844 · Cited by 303 · see citing works

Traumatic brain injury and time to onset of Alzheimer’s disease: a population-based study

Nemetz, P. N., Leibson, C., Naessens, J. M., Beard, M., Kokmen, E., Annegers, J. F., & Kurland, L. T. (1999) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009724 · Cited by 295 · see citing works

The morphological phenotype of β-amyloid plaques and associated neuritic changes in Alzheimer’s disease

Dickson, T. C., & Vickers, J. C. (2001) · Neuroscience · doi:10.1016/s0306-4522(01)00169-5 · Cited by 294 · see citing works

Biochemistry of altered brain proteins in Alzheimer's disease.

Selkoe, D. (1989) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.12.030189.002335 · Cited by 261 · see citing works

APOE4-specific Changes in Aβ Accumulation in a New Transgenic Mouse Model of Alzheimer Disease

Youmans, K. L., Tai, L. M., Nwabuisi-Heath, E., Jungbauer, L., Kanekiyo, T., Gan, M., Kim, J., Eimer, W. A., Estus, S., Rebeck, G. W., et al. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.407957 · Cited by 259 · cited 4× · see citing works

Controlled Cortical Impact Traumatic Brain Injury in 3xTg-AD Mice Causes Acute Intra-Axonal Amyloid-  Accumulation and Independently Accelerates the Development of Tau Abnormalities

Tran, H. T., LaFerla, F. M., Holtzman, D. M., & Brody, D. L. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.0858-11.2011 · Cited by 255 · see citing works

Immunohistochemical characterization of alterations in the distribution of amyloid precursor proteins and beta-amyloid peptide after experimental brain injury in the rat

Pierce, J., Trojanowski, J., Graham, D., Smith, D., & McIntosh, T. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-03-01083.1996 · Cited by 239 · cited 2× · see citing works

Temporal and regional patterns of axonal damage following traumatic brain injury: a beta-amyloid precursor protein immunocytochemical study in rats

BRAMLETT, H. M., KRAYDIEH, S., GREEN, E. J., & DIETRICH, W. D. (1997) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/00005072-199710000-00007 · Cited by 225 · see citing works

Early association of reactive astrocytes with senile plaques in Alzheimer's disease

Pike, C. J., Cummings, B. J., & Cotman, C. W. (1995) · Experimental Neurology · doi:10.1016/0014-4886(95)90022-5 · Cited by 199 · see citing works

Brain protein phosphatase 2A: Developmental regulation and distinct cellular and subcellular localization by B subunits

Strack, S., Zaucha, J. A., Ebner, F. F., Colbran, R. J., & Wadzinski, B. E. (1998) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19980323)392:4 · Cited by 181 · see citing works

Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody

Youmans, K. L., Tai, L. M., Kanekiyo, T., Stine Jr, W. B., Michon, S.-C., Nwabuisi-Heath, E., Manelli, A. M., Fu, Y., Riordan, S., Eimer, W. A., et al. (2012) · Molecular Neurodegeneration · doi:10.1186/1750-1326-7-8 · Cited by 164 · see citing works

Rapid appearance of β-amyloid precursor protein immunoreactivity in damaged axons and reactive glial cells in rat brain following needle stab injury

Otsuka, N., Tomonaga, M., & Ikeda, K. (1991) · Brain Research · doi:10.1016/0006-8993(91)91422-w · Cited by 155 · see citing works

Redefining the Role of Metallothionein within the Injured Brain

Chung, R. S., Penkowa, M., Dittmann, J., King, C., Bartlett, C. A., Asmussen, J. W., Hidalgo, J., Carrasco, J., Leung, Y. K., Walker, A. K., et al. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m708446200 · Cited by 153 · see citing works

Astrocytes containing amyloid beta-protein (Abeta)-positive granules are associated with Abeta40-positive diffuse plaques in the aged human brain.

(1998) · Europe PMC (PubMed Central) · Cited by 146 · see citing works

Brain Trauma Induces Massive Hippocampal Neuron Death Linked to a Surge in β-Amyloid Levels in Mice Overexpressing Mutant Amyloid Precursor Protein

Smith, D. H., Nakamura, M., McIntosh, T. K., Wang, J., Rodríguez, A., Chen, X.-H., Raghupathi, R., Saatman, K. E., Clemens, J., Schmidt, M. L., et al. (1998) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)65643-x · Cited by 143 · cited 3× · see citing works

Altered synapses and gliotransmission in Alzheimer's disease and AD model mice

Mitew, S., Kirkcaldie, M. T. K., Dickson, T. C., & Vickers, J. C. (2013) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2013.04.010 · Cited by 138 · see citing works

Metallothionein-IIA Promotes Initial Neurite Elongation and Postinjury Reactive Neurite Growth and Facilitates Healing after Focal Cortical Brain Injury

Chung, R. S., Vickers, J. C., Chuah, M. I., & West, A. K. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-08-03336.2003 · Cited by 124 · see citing works

Microglial cells are the driving force in fibrillar plaque formation, whereas astrocytes are a leading factor in plaque degradation

Wegiel, J., Wang, K. C., Tarnawski, M., & Lach, B. (2000) · Acta Neuropathologica · doi:10.1007/s004010000199 · Cited by 124 · see citing works

Amyloid oligomers: spectroscopic characterization of amyloidogenic protein states

Lindgren, M., & Hammarström, P. (2010) · FEBS Journal · doi:10.1111/j.1742-4658.2010.07571.x · Cited by 107 · see citing works

Microheterogeneity ("neurotypy") of neurofilament proteins.

Goldstein, M. E., Sternberger, L. A., & Sternberger, N. H. (1983) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.80.10.3101 · Cited by 103 · see citing works

Alzheimer's disease pathology in the neocortex and hippocampus of the western lowland gorilla (<i>Gorilla gorilla gorilla</i>)

Perez, S. E., Raghanti, M. A., Hof, P. R., Kramer, L., Ikonomovic, M. D., Lacor, P. N., Erwin, J. M., Sherwood, C. C., & Mufson, E. J. (2013) · Journal of Comparative Neurology · doi:10.1002/cne.23428 · Cited by 95 · cited 1× · see citing works

Brain Trauma in Aged Transgenic Mice Induces Regression of Established Aβ Deposits

Nakagawa, Y., Reed, L., Nakamura, M., McIntosh, T. K., Smith, D. H., Saatman, K. E., Raghupathi, R., Clemens, J., Saido, T. C., Lee, V. M.-Y., et al. (2000) · Experimental Neurology · doi:10.1006/exnr.2000.7375 · Cited by 91 · cited 3× · see citing works

Distinct temporal and anatomical distributions of amyloid-β and tau abnormalities following controlled cortical impact in transgenic mice

Tran, H. T., Sanchez, L., Esparza, T. J., & Brody, D. L. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025475 · Cited by 86 · see citing works

Models of Traumatic Brain Injury

Laurer, H. L., Lenzlinger, P. M., & McIntosh, T. K. (2000) · European Journal of Trauma · doi:10.1007/s000680050007 · Cited by 72 · see citing works

Neuron‐glia communication: metallothionein expression is specifically up‐regulated by astrocytes in response to neuronal injury

Chung, R. S., Adlard, P. A., Dittmann, J., Vickers, J. C., Chuah, M. I., & West, A. K. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.02193.x · Cited by 71 · see citing works

Alterations in neurofilaments associated with reactive brain changes and axonal sprouting following acute physical injury to the rat neocortex

King, C., Canty, A. J., & Vickers, J. C. (2001) · Neuropathology and Applied Neurobiology · doi:10.1046/j.1365-2990.2001.00317.x · Cited by 62 · see citing works

Systemic administration of fibroblast growth factor-2 (FGF2) reduces BACE1 expression and amyloid pathology in APP23 mice

Katsouri, L., Ashraf, A., Birch, A. M., Lee, K. K. L., Mirzaei, N., & Sastre, M. (2014) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2014.10.004 · Cited by 59 · see citing works

Dystrophic neurites in TgCRND8 and Tg2576 mice mimic human pathological brain aging

Woodhouse, A., Vickers, J. C., Adlard, P. A., & Dickson, T. C. (2007) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2007.09.003 · Cited by 50 · see citing works

Focal Damage to the Adult Rat Neocortex Induces Wound Healing Accompanied by Axonal Sprouting and Dendritic Structural Plasticity

Blizzard, C. A., Chuckowree, J. A., King, A. E., Hosie, K. A., McCormack, G. H., Chapman, J. A., Vickers, J. C., & Dickson, T. C. (2010) · Cerebral Cortex · doi:10.1093/cercor/bhq091 · Cited by 38 · see citing works

Human APOE genotype affects intraneuronal A 1-42 accumulation in a lentiviral gene transfer model

Zhao, W., Dumanis, S. B., Tamboli, I. Y., Rodriguez, G. A., Jo LaDu, M., Moussa, C. E. H., & William Rebeck, G. (2014) · Human Molecular Genetics · doi:10.1093/hmg/ddt525 · Cited by 32 · see citing works

Aging reduces glial uptake and promotes extracellular accumulation of Aβ from a lentiviral vector

Zhao, W., Zhang, J., Davis, E. G., & Rebeck, G. W. (2014) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2014.00210 · Cited by 25 · see citing works

Cortical Murine Neurons Lacking the Neurofilament Light Chain Protein Have an Attenuated Response to Injury In Vitro

Blizzard, C. A., King, A. E., Vickers, J. C., & Dickson, T. C. (2013) · Journal of Neurotrauma · doi:10.1089/neu.2013.2850 · Cited by 14 · see citing works

Metallothionein expression by NG2 glial cells following CNS injury

Chung, R. S., Fung, S. J., Leung, Y. K., Walker, A. K., McCormack, G. H., Chuah, M. I., Vickers, J. C., & West, A. K. (2007) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-007-7267-8 · Cited by 13 · see citing works

Untitled work

Nakagawa (1999) · doi:10.1002/(sici)1096-9861(19990830)411:3

The Inflammatory Continuum of Traumatic Brain Injury and Alzheimer’s Disease

Kokiko-Cochran, O. N., & Godbout, J. P. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00672 · Cited by 128 · see citing works

Chronic Toxoplasma gondii infection enhances β-amyloid phagocytosis and clearance by recruited monocytes

Möhle, L., Israël, N., Paarmann, K., Krohn, M., Pietkiewicz, S., Müller, A. J., Lavrik, I. N., Buguliskis, J. S., Schott, B. H., Schlüter, D., et al. (2016) · Acta Neuropathologica Communications · doi:10.1186/s40478-016-0293-8 · Cited by 101 · see citing works

Artemisinin Improved Neuronal Functions in Alzheimer's Disease Animal Model 3xtg Mice and Neuronal Cells via Stimulating the ERK/CREB Signaling Pathway

Zhao, X., Li, S., Gaur, U., & Zheng, W. (2020) · Aging and Disease · doi:10.14336/ad.2019.0813 · Cited by 91 · see citing works

Protective effect of paeoniflorin on inflammation and apoptosis in the cerebral cortex of a transgenic mouse model of Alzheimer's disease

Gu, X., CAI, Z., Cai, M., Liu, K., Liu, D., ZHANG, Q., Tan, J. H., & Ma, Q. (2016) · Molecular Medicine Reports · doi:10.3892/mmr.2016.4805 · Cited by 81 · see citing works

Platelets are responsible for the accumulation of β-amyloid in blood clots inside and around blood vessels in mouse brain after thrombosis

Kucheryavykh, L. Y., Dávila-Rodríguez, J., Rivera-Aponte, D. E., Zueva, L. V., Washington, A. V., Sanabria, P., & Inyushin, M. Y. (2016) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2016.11.008 · Cited by 68 · see citing works

Platelets mediate protective neuroinflammation and promote neuronal plasticity at the site of neuronal injury

Dukhinova, M., Kuznetsova, I. S., Kopeikina, E., Veniaminova, E. A., Yung, A. W. Y., Veremeyko, T., Levchuk, K., Barteneva, N. S., Wing-Ho, K. K., Yung, W., et al. (2018) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2018.09.009 · Cited by 60 · see citing works

Combination treatment with leptin and pioglitazone in a mouse model of Alzheimer's disease

Fernández-Martos, C. M., Atkinson, R. A. K., Chuah, M. I., King, A. E., & Vickers, J. C. (2016) · Alzheimer s & Dementia Translational Research & Clinical Interventions · doi:10.1016/j.trci.2016.11.002 · Cited by 50 · see citing works

An AIE-active theranostic probe for light-up detection of Aβ aggregates and protection of neuronal cells

Yang, Y., Li, S., Zhang, Q., Kuang, Y., Qin, A., Gao, M., Li, F., & Tang, B. Z. (2019) · Journal of Materials Chemistry B · doi:10.1039/c9tb00121b · Cited by 44 · see citing works

Mid‐life environmental enrichment increases synaptic density in CA1 in a mouse model of Aβ‐associated pathology and positively influences synaptic and cognitive health in healthy ageing

Stuart, K. E., King, A. E., Fernández-Martos, C. M., Dittmann, J., Summers, M. J., & Vickers, J. C. (2016) · The Journal of Comparative Neurology · doi:10.1002/cne.24156 · Cited by 39 · see citing works

Synaptic aging disrupts synaptic morphology and function in cerebellar Purkinje cells

Wang, L., Deng, J., Fan, W., Yan, M., Sun, Y.-Z., & Deng, J.-X. (2018) · Neural Regeneration Research · doi:10.4103/1673-5374.233445 · Cited by 37 · see citing works

Serum amyloid A1 is involved in amyloid plaque aggregation and memory decline in amyloid beta abundant condition

Jang, S., Jang, W. Y., Choi, M., Lee, J., Kwon, W., Yi, J., Park, S. J., Yoon, D., Lee, S., Kim, M. O., et al. (2019) · Transgenic Research · doi:10.1007/s11248-019-00166-x · Cited by 35 · see citing works

Amyloidosis is associated with thicker myelin and increased oligodendrogenesis in the adult mouse brain

Ferreira, S., Pitman, K. A., Wang, S., Summers, B. S., Bye, N., Young, K. M., & Cullen, C. L. (2020) · Journal of Neuroscience Research · doi:10.1002/jnr.24672 · Cited by 36 · see citing works

Spinal cord injury and Alzheimer’s disease risk: a population-based, retrospective cohort study

Yeh, T., Ho, Y., Hsu, C., & Pan, S. (2017) · Spinal Cord · doi:10.1038/s41393-017-0009-3 · Cited by 33 · see citing works

Clofibrate, a PPAR‐α agonist, abrogates sodium fluoride‐induced neuroinflammation, oxidative stress, and motor incoordination via modulation of GFAP/Iba‐1/anti‐calbindin signaling pathways

Oyagbemi, A. A., Adebiyi, O. E., Adigun, K. O., Ogunpolu, B. S., Falayi, O. O., Hassan, F. O., Folarin, O. R., Adebayo, A. K., Adejumobi, O. A., Asenuga, E. R., et al. (2019) · Environmental Toxicology · doi:10.1002/tox.22861 · Cited by 29 · see citing works

Long-Term Effects of Traumatic Brain Injury in a Mouse Model of Alzheimer’s Disease

Zyśk, M., Clausen, F., Aguilar, X., Sehlin, D., Syvänen, S., & Erlandsson, A. (2019) · Journal of Alzheimer s Disease · doi:10.3233/jad-190572 · Cited by 30 · see citing works

Alzheimer's disease in the gut—Major changes in the gut of 5xFAD model mice with ApoA1 as potential key player

Stoye, N. M., Guilherme, M. D. S., & Endres, K. (2020) · The FASEB Journal · doi:10.1096/fj.201903128rr · Cited by 28 · see citing works

Spatial Training Ameliorates Long-Term Alzheimer's Disease-Like Pathological Deficits by Reducing NLRP3 Inflammasomes in PR5 Mice

Ren, Q., Gong, W.-G., Zhou, H., Shu, H., Wang, Y., & Zhang, Z. (2018) · Neurotherapeutics · doi:10.1007/s13311-018-00698-w · Cited by 26 · see citing works

Late-life environmental enrichment preserves short-term memory and may attenuate microglia in male APP/PS1 mice

Stuart, K. E., King, A. E., King, N. E., Collins, J. M., Vickers, J. C., & Ziebell, J. M. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.04.015 · Cited by 27 · see citing works

Environmental novelty exacerbates stress hormones and Aβ pathology in an Alzheimer’s model

Stuart, K., King, A., Fernandez-Martos, C. M., Summers, M., & Vickers, J. (2017) · Scientific Reports · doi:10.1038/s41598-017-03016-0 · Cited by 22 · see citing works

Patchouli alcohol as a selective estrogen receptor β agonist ameliorates AD-like pathology of APP/PS1 model mice

Yan, Q., Lv, J., Shen, X., Yang, J., Yang, J.-Z., Nie, R.-F., Lu, J., Huang, Y.-J., Wang, J.-Y., & Shen, X. (2022) · Acta Pharmacologica Sinica · doi:10.1038/s41401-021-00857-4 · Cited by 25 · see citing works

Traumatic Brain Injury Alters the Metabolism and Facilitates Alzheimer’s Disease in a Murine Model

Lou, D., Du, Y., Huang, D., Cai, F., Zhang, Y. L., Li, T.-Y., Zhou, W., Gao, H., & Song, W. (2017) · Molecular Neurobiology · doi:10.1007/s12035-017-0687-z · Cited by 23 · see citing works

Amyloid Beta Peptide Is Released during Thrombosis in the Skin

Kucheryavykh, L. Y., Kucheryavykh, Y. V., Washington, A. V., & Inyushin, M. Y. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19061705 · Cited by 20 · see citing works

Curcumin abrogates cobalt-induced neuroinflammation by suppressing proinflammatory cytokines release, inhibiting microgliosis and modulation of ERK/MAPK signaling pathway

Oria, R. S., Anyanwu, G. E., Nto, N. J., & Ikpa, J. O. (2024) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2024.102402 · Cited by 18 · see citing works

Age Moderates the Effects of Traumatic Brain Injury on Beta-Amyloid Plaque Load in APP/PS1 Mice

Collins, J. M., King, A. E., Woodhouse, A., Kirkcaldie, M., & Vickers, J. C. (2019) · Journal of Neurotrauma · doi:10.1089/neu.2018.5982 · Cited by 16 · see citing works

Paeonol administration alleviates cognitive deficits and attenuates neural pathological changes in APP/PS1 mice

Meng, S., Wang, B., & Li, W. (2021) · Journal of Integrative Neuroscience · doi:10.31083/j.jin2004101 · Cited by 14 · see citing works

The antioxidant role of aromatic plant extracts in managing neurodegenerative diseases: A comprehensive review

Zhu, Y., Tian, M., Lu, S., Qin, Y., Zhao, T. S., Shi, H., Li, Z., & Qin, D. (2025) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2025.111253 · Cited by 13 · see citing works

Repeat propofol anesthesia does not exacerbate plaque deposition or synapse loss in APP/PS1 Alzheimer’s disease mice

Woodhouse, A., Fernández-Martos, C. M., Atkinson, R. A. K., Hanson, K., Collins, J. M., O'Mara, A., Terblanche, N., Skinner, M. W., Vickers, J. C., & King, A. E. (2018) · BMC Anesthesiology · doi:10.1186/s12871-018-0509-5 · Cited by 13 · see citing works

TDP-43 mislocalization drives neurofilament changes in a novel model of TDP-43 proteinopathy

Atkinson, R. A. K., Leung, J. Y. K., Bender, J. A., Kirkcaldie, M., Vickers, J. C., & King, A. E. (2021) · Disease Models & Mechanisms · doi:10.1242/dmm.047548 · Cited by 13 · see citing works

Regional differences in beta amyloid plaque deposition and variable response to midlife environmental enrichment in the cortex of APP/PS1 mice

Fulopova, B., Stuart, K., Bennett, W., Bindoff, A., King, A., Vickers, J., & Canty, A. (2020) · The Journal of comparative neurology · doi:10.1002/cne.25060 · Cited by 11 · see citing works

The Emergence of Model Systems to Investigate the Link Between Traumatic Brain Injury and Alzheimer’s Disease

Srinivasan, G. R., & Brafman, D. A. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.813544 · Cited by 10 · see citing works

Microglia Demonstrate Local Mixed Inflammation and a Defined Morphological Shift in an APP/PS1 Mouse Model

Holloway, O. G., King, A. E., & Ziebell, J. M. (2020) · Journal of Alzheimer s Disease · doi:10.3233/jad-200098 · Cited by 9 · see citing works

Spatial Patterns of Amyloid Deposition in Patients with Chronic Focal or Diffuse Traumatic Brain Injury Using 18F-FPYBF-2 PET

Ubukata, S., Oishi, N., Higashi, T., Kagawa, S., Yamauchi, H., Okuyama, C., Watanabe, H., Ono, M., Saji, H., Aso, T., et al. (2020) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s268504 · Cited by 9 · see citing works

Enhanced Anti-Amyloid Effect of Combined Leptin and Pioglitazone in APP/PS1 Transgenic Mice

Liu, Y., Hanson, K., McCormack, G. H., Atkinson, R. A. K., Dittmann, J., Vickers, J. C., Fernández-Martos, C. M., & King, A. E. (2021) · Current Alzheimer Research · doi:10.2174/1567205018666210218163857 · Cited by 9 · see citing works

PK2/PKRs pathway is involved in the protective effect of artemisinin against trimethyltin chloride-induced hippocampal injury

Gao, Y., Liao, W., Zhang, R., Lei, Y., Chen, T., Wu, L., Li, M., Liu, X., & Cai, F. (2023) · Toxicology · doi:10.1016/j.tox.2023.153432 · Cited by 8 · see citing works

Alzheimer’s Disease Mouse as a Model of Testis Degeneration

Szegeczki, V., Horváth, G., Perényi, H., Tamás, A., Radak, Z. O., Ábrahám, D., Zákány, R., Reglődi, D., & Juhász, T. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21165726 · Cited by 7 · see citing works

Pathological Links between Traumatic Brain Injury and Dementia: Australian Pre-Clinical Research

Collins, J. M., Woodhouse, A., Bye, N., Vickers, J. C., King, A. E., & Ziebell, J. M. (2020) · Journal of Neurotrauma · doi:10.1089/neu.2019.6906 · Cited by 7 · see citing works

Can brain impermeable BACE1 inhibitors serve as anti-CAA medicine?

Li, J., Huang, L., Liu, F., Tang, B., & Yan, X. (2017) · BMC Neurology · doi:10.1186/s12883-017-0942-y · Cited by 5 · see citing works

Distribution of LIM domain kinase 1 in the olfactory bulb, cerebral cortex, hippocampus, and cerebellum of the App/PS+/- mice

An, L., Liu, J., Li, W., Shi, Y. J., Lin, X. H., Yu, D. M., Deng, J., & Ren, X. Q. (2015) · Genetics and Molecular Research · doi:10.4238/2015.december.16.24 · Cited by 3 · see citing works

Traumatic brain injury induces a sustained sensorimotor impairment associated with a dysregulated acute phase response in mice overexpressing human amyloid precursor protein

McLeod, R. E., Kale, K. M., Weglinski, C., Masoud, A. M., Akbar, N., Probert, F., Anthony, D. C., & Zainal, J. (2025) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2025.07.027 · Cited by 2 · see citing works

Traumatic Injury Reduces Amyloid Plaque Burden in the Transgenic 5xFAD Alzheimer’s Mouse Spinal Cord

Chu, T., Cummins, K., & Stys, P. K. (2020) · Journal of Alzheimer s Disease · doi:10.3233/jad-200387 · Cited by 2 · see citing works

Mechanisms of amyloid-beta cytotoxicity in hippocampal network function : rescue strategies in Alzheimer's disease

Kurudenkandy, F. R. (2016) · Figshare

What Happens to Concussed Animals?

Victoroff, J. (2019) · Cambridge University Press eBooks · doi:10.1017/9781139696432.006

Creation of single App knock-in mouse models and of single MAPT knock-in models: Demonstration of Aβ-tau axis

Saido, T. C. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-28979-8.00023-1

New thin-layer chromatographic solvent systems for separating steroid hormones

Duthie, A. H., Simmons, K. R., & Urey, B. R. (1969) · Journal of Chromatography A · doi:10.1016/s0021-9673(01)92521-x · Cited by 1 · see citing works

The effect of traumatic brain injury in experimental models of Alzheimer's disease

Collins, J. (2016) · UTAS Research Repository · doi:10.25959/23239286

Age Moderates the Effects of Traumatic Brain Injury on Beta-Amyloid Plaque Load in APP/PS1 Mice

Collins, J. M., King, A. E., Woodhouse, A., Kirkcaldie, M., & Vickers, J. C. (2019) · Journal of Neurotrauma · doi:10.1089/neu.2018.5982 · Cited by 16 · see citing works

Seeding of β-amyloidosis in βAPP-transgenic mice by the intracerebral injection of Alzheimer brain extract

Walker, L. C., Lipinski, W. J., Callahan, M. J., Bian, F., Durham, R. A., Schwartz, R. D., Roher, A. E., & Kane, M. D. (2000) · Neurobiology of Aging · doi:10.1016/s0197-4580(00)82366-0

Traumatic Brain Injury Modulates Synuclein-Associated Transcription, Amyloid Plaque Morphology and Cognitive Performance in APPswe/PS1dE9/Blg Mice

Apostol, A., Kuzubova, E. V., Radchenko, A. I., Chaprov, K., Щеблыкина, О. В., Романович, Л. П., Korokina, L. V., Pokrovskii, M., Sedinova, V. N., Khizeva, A., et al. (2026) · Biomedicines · doi:10.3390/biomedicines14071524