Mindfulness-Based Program for Infertility: Efficacy study
Open accessAbstract
Objective To present and determine the impact of the Mindfulness-Based Program for Infertility (MBPI). Design Controlled clinical trial. Setting University research unit. Patient(s) Fifty-five infertile women completed the MBPI, and 37 infertile women were assigned to a control group. Intervention(s) The MBPI includes 10 weekly sessions, in a group format, with a duration of about 2 hours each (men attend three sessions). Main Outcome Measure(s) Standardized measures of depression, state anxiety, entrapment, defeat, internal and external shame, experiential avoidance, mindfulness, self-compassion, and infertility self-efficacy were endorsed pre- and post-MBPI. Result(s) The MBPI group and the control group were shown to be equivalent at baseline. By the end of the MBPI, women who attended the program revealed a significant decrease in depressive symptoms, internal and external shame, entrapment, and defeat. Inversely, they presented statistically significant improvement in mindfulness skills and self-efficacy to deal with infertility. Women in the control group did not present significant changes in any of the psychological measures, except for a decrease in self-judgment. Conclusion(s) Increasing mindfulness and acceptance skills, as well as cognitive decentering from thoughts and feelings, seem to help women to experience negative inner states in new ways, decreasing their entanglement with them and thus their psychological distress. Data suggest that the MBPI is an effective psychological intervention for women experiencing infertility. Copyright © 2013 American Society for Reproductive Medicine, Published by Elsevier Inc.
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5 of 20 cited sources checked · 3 supported · 0 flagged · accuracy not yet measured
- Study design and conductcitation
The study included an experimental and a control group.
“By examining this efficacy study on the basis of quality indicators proposed by Hammerli and colleagues (15), we can see that standardized psychological measures were used as dependent variables, the study included an experimental and a control group, and inclusion criteria were established.”
Quote in the paperSubstantial claim1 of 1 sources checked- cites [15] Hammerli, 2009, The efficacy of psychological interventions for infertile patients: a meta-analysis examining mental health and 370 pregnancy rate, Hum Reprod Update source
- Premisecitation
Analysis of 21 controlled studies on the effectiveness of psychological interventions targeting infertile patients shows that only seven of these studies were conducted on samples of greater size than ours.
“However, analysis of 21 controlled studies on the effectiveness of psychological interventions targeting infertile patients (15) shows that only seven of these studies were conducted on samples of greater size than ours.”
Quote in the paperSubstantial claim1 of 1 sources checked- cites [15] Hammerli, 2009, The efficacy of psychological interventions for infertile patients: a meta-analysis examining mental health and 370 pregnancy rate, Hum Reprod Update source
The Description of studies reports 21 controlled studies of psychological interventions for infertile patients, and Table I lists their sample sizes (page numbers unavailable). The source does not identify the citing study’s sample size or state that exactly seven studies were larger, so that comparison is not established by our copy. (LLM, conf=0.83)
Experimental — accuracy not yet measured
- Findingown data
No significant time × group interaction effect was found for self-judgment.
“No significant time  group interaction effects were found in anxiety, psychological inflexibility/experiential avoidance, self-compassion, or self-judgment.”
Quote in the paperNot a substantial claim - Findingown data
In the MBPI group, a significant decrease was found in internal shame from T1 to T2.
“a significant decrease was found in: depression, external shame, internal shame, external entrapment, internal entrapment, and defeat.”
Quote in the paperSubstantial claim - Findingown data
A significant time × group interaction effect was found for external shame, with medium effect size.
“Significant time  group interaction effects were found for depression, external shame, internal shame, external entrapment and internal entrapment, defeat, and selfefficacy to deal with infertility, all of them with medium effect sizes.”
Quote in the paperSubstantial claim
- Findingown data
In the MBPI group, a significant decrease was found in depression from T1 to T2.
“a significant decrease was found in: depression, external shame, internal shame, external entrapment, internal entrapment, and defeat.”
Quote in the paperSubstantial claim - Findingown data
A significant time × group interaction effect was found for internal entrapment, with medium effect size.
“Significant time  group interaction effects were found for depression, external shame, internal shame, external entrapment and internal entrapment, defeat, and selfefficacy to deal with infertility, all of them with medium effect sizes.”
Quote in the paperSubstantial claim - Findingown data
A significant direct effect of time was found for depression, with medium effect size.
“a significant direct effect of time was found for depression, external shame, internal shame, external entrapment, internal entrapment, defeat, psychological inflexibility/experiential avoidance, selfjudgment, and self-efficacy to deal with infertility.”
Quote in the paperSubstantial claim - Findingown data
No significant time × group interaction effect was found for anxiety.
“No significant time  group interaction effects were found in anxiety, psychological inflexibility/experiential avoidance, self-compassion, or self-judgment.”
Quote in the paperNot a substantial claim - Findingown data
A significant time × group interaction effect was found for depression, with medium effect size.
“Significant time  group interaction effects were found for depression, external shame, internal shame, external entrapment and internal entrapment, defeat, and selfefficacy to deal with infertility, all of them with medium effect sizes.”
Quote in the paperSubstantial claim - Findingown data
No significant direct group effects were found in any of the studied variables.
“No significant direct group effects were found in any of the studied variables.”
Quote in the paperSubstantial claim - Findingown data
A significant direct effect of time was found for self-efficacy to deal with infertility, with medium effect size.
“a significant direct effect of time was found for depression, external shame, internal shame, external entrapment, internal entrapment, defeat, psychological inflexibility/experiential avoidance, selfjudgment, and self-efficacy to deal with infertility.”
Quote in the paperSubstantial claim - Findingown data
In the MBPI group, a significant decrease was found in external shame from T1 to T2.
“a significant decrease was found in: depression, external shame, internal shame, external entrapment, internal entrapment, and defeat.”
Quote in the paperSubstantial claim - Findingown data
A significant direct effect of time was found for self-judgment, with medium effect size.
“a significant direct effect of time was found for depression, external shame, internal shame, external entrapment, internal entrapment, defeat, psychological inflexibility/experiential avoidance, selfjudgment, and self-efficacy to deal with infertility.”
Quote in the paperSubstantial claim - Findingown data
A significant time × group interaction effect was found for defeat, with medium effect size.
“Significant time  group interaction effects were found for depression, external shame, internal shame, external entrapment and internal entrapment, defeat, and selfefficacy to deal with infertility, all of them with medium effect sizes.”
Quote in the paperSubstantial claim - Findingown data
No significant direct time effects were found regarding self-compassion.
“There were no significant direct time effects regarding self-compassion.”
Quote in the paperNot a substantial claim - Findingown data
A significant direct effect of time was found for external shame, with medium effect size.
“a significant direct effect of time was found for depression, external shame, internal shame, external entrapment, internal entrapment, defeat, psychological inflexibility/experiential avoidance, selfjudgment, and self-efficacy to deal with infertility.”
Quote in the paperSubstantial claim - Findingown data
A significant time × group interaction effect was found for self-efficacy to deal with infertility, with medium effect size.
“Significant time  group interaction effects were found for depression, external shame, internal shame, external entrapment and internal entrapment, defeat, and selfefficacy to deal with infertility, all of them with medium effect sizes.”
Quote in the paperSubstantial claim - Findingown data
A significant time × group interaction effect was found for external entrapment, with medium effect size.
“Significant time  group interaction effects were found for depression, external shame, internal shame, external entrapment and internal entrapment, defeat, and selfefficacy to deal with infertility, all of them with medium effect sizes.”
Quote in the paperSubstantial claim - Findingown data
No significant time × group interaction effect was found for psychological inflexibility/experiential avoidance.
“No significant time  group interaction effects were found in anxiety, psychological inflexibility/experiential avoidance, self-compassion, or self-judgment.”
Quote in the paperNot a substantial claim - Findingown data
No significant time × group interaction effect was found for self-compassion.
“No significant time  group interaction effects were found in anxiety, psychological inflexibility/experiential avoidance, self-compassion, or self-judgment.”
Quote in the paperNot a substantial claim - Findingown data
A significant time × group interaction effect was found for internal shame, with medium effect size.
“Significant time  group interaction effects were found for depression, external shame, internal shame, external entrapment and internal entrapment, defeat, and selfefficacy to deal with infertility, all of them with medium effect sizes.”
Quote in the paperSubstantial claim - Findingnone given
Perception of ability to engage in cognitive, emotional, and behavioral skills related to the medical treatment of infertility was significantly improved in MBPI participants.
“Perception about their ability to engage in a set of cognitive, emotional, and behavioral skills related to the medical treatment of infertility was also significantly improved in MBPI participants.”
Quote in the paperSubstantial claim - Findingcitation
MBPI participants showed less external shame, seeing themselves as existing in the minds of others as someone with less negative characteristics.
“In addition, they seem to see themselves as existing in the mind of the others as someone with less negative characteristics, showing less external shame (35,56).”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [35] Gilbert, 1998, The role of defeat and entrapment (arrested flight) in depression: an exploration of an evolutionary view, Psychol Med source
- cites [56] Gilbert, 2002, Body shame: a biopsychosocial conceptualization and overview, with treatment implications
Not checked in the free run.
- Findingown data
In the MBPI group, no differences were found in self-compassion.
“No differences were found in self-compassion.”
Quote in the paperNot a substantial claim - Findingown data
In the MBPI group, a significant decrease was found in internal entrapment from T1 to T2.
“a significant decrease was found in: depression, external shame, internal shame, external entrapment, internal entrapment, and defeat.”
Quote in the paperSubstantial claim - Findingown data
In the MBPI group, there was also a significant decrease in anxiety from T1 to T2.
“In the MBPI group, there was also a significant decrease in anxiety, experiential avoidance, and self-judgment.”
Quote in the paperNot a substantial claim - Findingown data
In the MBPI group, 18 (32.7%) participants started infertility treatment.
“In the MBPI group, 18 (32.7%)participants started infertility treatment.”
Quote in the paperNot a substantial claim - Findingown data
In the MBPI group, a significant decrease was found in defeat from T1 to T2.
“a significant decrease was found in: depression, external shame, internal shame, external entrapment, internal entrapment, and defeat.”
Quote in the paperSubstantial claim - Findingreasoning
MBPI participants perceived themselves less negatively regarding internal shame, as less inadequate, different, unlovable, or unworthy.
“As for internal and external shame, MBPI participants seem to perceive themselves less negatively, as less inadequate, different, unlovable, or unworthy (internal shame).”
Quote in the paperSubstantial claim - Findingown data
In the MBPI group, a significant decrease was found in external entrapment from T1 to T2.
“a significant decrease was found in: depression, external shame, internal shame, external entrapment, internal entrapment, and defeat.”
Quote in the paperSubstantial claim - Findingown data
Within the MBPI group, participants had decreased experiential avoidance.
“When considering mean comparisons within the MBPI group, we also found that participants have decreased anxiety symptoms, self-judgment, and experiential avoidance.”
Quote in the paperSubstantial claim - Findingown data
Preliminary data point to the maintenance of therapeutic gains at a 6-month follow-up.
“Preliminary data also point to the maintenance of therapeutic gains at a 6-month follow-up, and further research is being carried out in this context.”
Quote in the paperNot a substantial claim - Findingown data
Half of the participants in the control group started medical treatment during the period of the MBPI application.
“Moreover, half of the participants in this group started medical treatment during the period of the MBPI application, which may have helped them to feel more supported, less isolated, and less identified with the problem.”
Quote in the paperSubstantial claim - Findingown data
In the MBPI group, there was also a significant decrease in self-judgment from T1 to T2.
“In the MBPI group, there was also a significant decrease in anxiety, experiential avoidance, and self-judgment.”
Quote in the paperNot a substantial claim - Findingown data
In a subgroup of 30 MBPI participants, mindfulness skills significantly increased from T1 (mean 34.00, SD 5.05) to T2 (mean 38.40, SD 5.57), t(54)=-4.24, P<.001, eta2=.38.
“mindfulness skills were also assessed in a subgroup of 30 MBPI participants and a significant increase [t(54) ¼ À4.24, P< .001,h 2 ¼ .38]from T1 (mean ¼ 34.00, SD ¼ 5.05) to T2 (mean ¼ 38.40, SD ¼ 5.57) occurred.”
Quote in the paperNot a substantial claim - Findingown data
Within the MBPI group, participants had decreased self-judgment.
“When considering mean comparisons within the MBPI group, we also found that participants have decreased anxiety symptoms, self-judgment, and experiential avoidance.”
Quote in the paperSubstantial claim - Findingown data
In the MBPI group, there was a significant increase in self-efficacy to deal with infertility from T1 to T2.
“there was a significant increase in self-efficacy to deal with infertility.”
Quote in the paperSubstantial claim - Findingown data
Within the MBPI group, participants had decreased anxiety symptoms.
“When considering mean comparisons within the MBPI group, we also found that participants have decreased anxiety symptoms, self-judgment, and experiential avoidance.”
Quote in the paperSubstantial claim - Findingown data
In the MBPI group, there was also a significant decrease in experiential avoidance from T1 to T2.
“In the MBPI group, there was also a significant decrease in anxiety, experiential avoidance, and self-judgment.”
Quote in the paperNot a substantial claim - Findingown data
Women in the control group did not present significant changes in any psychological measures, except for self-judgment.
“Women in the control group did not present significant changes in any of the psychological measures, except for self-judgment.”
Quote in the paperSubstantial claim - Study design and conductown data
The MBPI group and the control group were equivalent at baseline.
“The MBPI group and the control group were shown to be equivalent at baseline.”
- Also stated in: § RESULTS · plain
“The MBPI group and the control group did not present significant differences in any of the variables, making them equivalent at baseline.”
Quote in the paperSubstantial claim - Also stated in: § RESULTS · plain
- Interpretationown data
The MBPI is an effective psychological intervention for women experiencing infertility.
“Our findings suggest that the MBPI is an effective psychological intervention for women experiencing infertility.”
- Also stated in: § DISCUSSION · hedged
“Thus, despite the limitations mentioned, results point to the effectiveness of the MBPI.”
Quote in the paperSubstantial claim- Rests on an assumption: The control group resembles a waiting list-type control group.
- Also stated in: § DISCUSSION · hedged
- Interpretationreasoning
MBPI participants adopted a less self-critical attitude.
“Moreover, they tend to feel less isolated, adopt a less self-critical attitude, and be less entangled with their infertility problem.”
Quote in the paperSubstantial claim - Interpretationcitation
The decrease in entrapment and defeat in the MBPI group means that the way these women perceive things in the outside world, as well as their internal feelings and thoughts, induce less escape motivation.
“Depression is also related to entrapment and defeat, and our results also show a decrease in these variables, meaning that the way these women perceive things in the outside world, as well as their internal feelings and thoughts, induce less escape motivation (35).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [35] Gilbert, 1998, The role of defeat and entrapment (arrested flight) in depression: an exploration of an evolutionary view, Psychol Med source
- Interpretationreasoning
Participants in the MBPI program became more conscious of their internal and external experience in the present moment with an attitude of openness and curiosity.
“Through mindfulness practice, participants became more conscious of their internal and external experience in the present moment with an attitude of openness and curiosity.”
Quote in the paperSubstantial claim - Interpretationown data
Data suggest that the MBPI is an effective psychological intervention for women experiencing infertility.
“Data suggest that the MBPI is an effective psychological intervention for women experiencing infertility.”
Quote in the paperSubstantial claim - Interpretationreasoning
MBPI participants were less entangled with their infertility problem.
“Moreover, they tend to feel less isolated, adopt a less self-critical attitude, and be less entangled with their infertility problem.”
Quote in the paperSubstantial claim - Interpretationreasoning
MBPI participants recognized painful thoughts and feelings related to the past or future without trying to suppress or modify them.
“Thus, painful thoughts and feelings related to the past (e.g., ''previous abortion'') or to the future (e.g., ''I will never be a mother'') are recognized without trying to suppress or modify them.”
Quote in the paperNot a substantial claim - Study design and conductnone given
The criteria for distribution to the experimental or control group was of a geographical nature.
“The criteria for their distribution to the experimental or the control group was of a geographical nature, and participants in the control group were given the opportunity to participate in future MBPI editions.”
Quote in the paperSubstantial claim - Interpretationown data
Results may indicate that the MBPI can be applied to infertility patients regardless of the treatment stage they are in, treatment approach, and infertility history.
“Even so, results may indicate that the MBPI can be applied to infertility patients regardless of the treatment stage they are in, treatment approach, and infertility history.”
Quote in the paperSubstantial claim - Study design and conductown data
The dropout rate before group allocation did not exceed 12.2%.
“The dropout rate before group allocation did not exceed 12.2%, which is favorable (values below 20% are considered good).”
Quote in the paperNot a substantial claim - Premisecitation
Depression is related to entrapment and defeat.
“Depression is also related to entrapment and defeat”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [35] Gilbert, 1998, The role of defeat and entrapment (arrested flight) in depression: an exploration of an evolutionary view, Psychol Med source
- Interpretationreasoning
MBPI participants tended to feel less isolated.
“Moreover, they tend to feel less isolated, adopt a less self-critical attitude, and be less entangled with their infertility problem.”
Quote in the paperNot a substantial claim - Interpretationcitation
Through metaphors, MBPI participants were able to compare their relationship with their own thoughts with that of someone who struggles with these thoughts instead of living their life.
“Through metaphors (e.g., bus and passengers metaphor) (22), participants were able to compare their relationship with their own thoughts with that of someone who struggles with these thoughts instead of living their life.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [22] Hayes, 1999
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Study design and conductnone given
Throughout the study, considering baseline assessment and post-MBPI, there was no attrition bias.
“Throughout the study, considering baseline assessment and post-MBPI, there was no attrition bias.”
Quote in the paperSubstantial claim
- Classified as probably not a substantial claim. 22
- May combine two claims. 25
- The quote only partly states this claim. 5
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductcitationInclusion criteria were established.
“By examining this efficacy study on the basis of quality indicators proposed by Hammerli and colleagues (15), we can see that standardized psychological measures were used as dependent variables, the study included an experimental and a control group, and inclusion criteria were established.”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites [15] Hammerli, 2009, The efficacy of psychological interventions for infertile patients: a meta-analysis examining mental health and 370 pregnancy rate, Hum Reprod Update source
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductcitationStandardized psychological measures were used as dependent variables.
“By examining this efficacy study on the basis of quality indicators proposed by Hammerli and colleagues (15), we can see that standardized psychological measures were used as dependent variables, the study included an experimental and a control group, and inclusion criteria were established.”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites [15] Hammerli, 2009, The efficacy of psychological interventions for infertile patients: a meta-analysis examining mental health and 370 pregnancy rate, Hum Reprod Update source
May combine two claims.
InterpretationcitationMBPI participants seemed more capable of accepting their adverse inner mental states and had more psychological flexibility.
“They seem to be more capable of accepting their adverse inner mental states (e.g., feelings, thoughts, bodily sensations) and have more psychological flexibility (26,38), which makes them more capable of conscious and deliberate actions, guided by their values, in a flexible and adaptable way (25).”
Quote in the paperSubstantial claim1 of 3 sources checked- cites [26] Hayes, 2005
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites [38] Bond, 2011, Preliminary psychometric properties of the Acceptance and Action Questionnaire II: a revised measure of psychological flexibility and acceptance, Behav Ther source
The ACT model section describes acceptance of unwanted thoughts, feelings, and physiological sensations as an aspect of psychological flexibility. It does not study MBPI participants or establish that they became more accepting or psychologically flexible; that participant-specific part is not supported by this source. (LLM, conf=0.86)
Experimental — accuracy not yet measured - cites [25] Harris, 2009
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
The quote only partly states this claim.
Findingown dataA significant direct effect of time was found for internal shame, with medium effect size.
“a significant direct effect of time was found for depression, external shame, internal shame, external entrapment, internal entrapment, defeat, psychological inflexibility/experiential avoidance, selfjudgment, and self-efficacy to deal with infertility.”
Quote in the paperSubstantial claimThe quote only partly states this claim.
Findingown dataA significant direct effect of time was found for defeat, with medium effect size.
“a significant direct effect of time was found for depression, external shame, internal shame, external entrapment, internal entrapment, defeat, psychological inflexibility/experiential avoidance, selfjudgment, and self-efficacy to deal with infertility.”
Quote in the paperSubstantial claimThe quote only partly states this claim.
Findingown dataA significant direct effect of time was found for external entrapment, with medium effect size.
“a significant direct effect of time was found for depression, external shame, internal shame, external entrapment, internal entrapment, defeat, psychological inflexibility/experiential avoidance, selfjudgment, and self-efficacy to deal with infertility.”
Quote in the paperSubstantial claimThe quote only partly states this claim.
Findingown dataA significant direct effect of time was found for internal entrapment, with medium effect size.
“a significant direct effect of time was found for depression, external shame, internal shame, external entrapment, internal entrapment, defeat, psychological inflexibility/experiential avoidance, selfjudgment, and self-efficacy to deal with infertility.”
Quote in the paperSubstantial claimThe quote only partly states this claim.
Findingown dataA significant direct effect of time was found for psychological inflexibility/experiential avoidance, with medium effect size.
“a significant direct effect of time was found for depression, external shame, internal shame, external entrapment, internal entrapment, defeat, psychological inflexibility/experiential avoidance, selfjudgment, and self-efficacy to deal with infertility.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataIn the control group, no differences were found in any of the considered variables, except for a significant decrease in self-judgment.
“The same analysis was conducted in the control group, and no differences were found in any of the considered variables, except for a significant decrease in self-judgment.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataThe MBPI particularly contributes to a decrease in depressive symptoms and an increase in patients' mindfulness skills and perception of their own ability to deal with infertility in a favorable manner.
“In fact, this program seems to particularly contribute to a decrease in depressive symptoms and an increase in patients' mindfulness skills and perception of their own ability to deal with infertility in a favorable manner.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataEffects of MBPI were found on several measures, including psychopathology, emotion regulation processes, mindfulness skills, and perception of ability to cope with the demands of infertility and its medical treatment.
“Effects were found on several measures, not only regarding psychopathology, but also in terms of emotion regulation processes, mindfulness skills, and the way participants perceive their ability to cope with the demands of infertility and its medical treatment.”
Quote in the paperSubstantial claimMay combine two claims.
Study design and conductown dataDifferences in age were found between groups, but age did not correlate with dependent variables.
“Differences in age were found, but age did not correlate with dependent variables.”
Quote in the paperNot a substantial claimMay combine two claims.
Study design and conductown dataNo significant differences were found regarding clinical variables except for medical treatment previous to study participation and current medical treatment approach, but these variables did not correlate with dependent variables.
“No significant differences were found regarding clinical variables except for medical treatment previous to the study participation and current medical treatment approach, but these variables did not correlate with dependent variables.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim. May combine two claims.
PremisecitationInfertility is a stressful condition with psychological burden, described by couples as a very demanding life crisis.
“It has been described as a stressful condition not only from a medical perspective but also in terms of psychological burden, with couples stating that it corresponds to a very demanding life crisis (1-3).”
Quote in the paperSubstantial claim0 of 3 sources checkedMay combine two claims.
Study design and conductown dataThe groups were equivalent in years of education and years of marriage.
“The groups were equivalent in years of education and years of marriage.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim.
PremisecitationSeveral mindfulness-based interventions have been applied and proved effective in numerous health problems such as chronic pain, cancer, anxiety disorders, depression, and so on.
“Several mindfulness-based interventions have been applied and proved effective in numerous health problems such as chronic pain, cancer, anxiety disorders, depression, and so on (19)”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [19] Baer, 2003, Mindfulness training as a clinical intervention: a conceptual and empirical review, Clin Psychol Sci Pract source
May combine two claims.
PremisecitationMost couples adjust and cope with infertility, but others present problematic emotional responses such as depression and anxiety.
“Most couples are able to adjust and cope with infertility, but others present problematic emotional responses such as depression and anxiety (11,12).”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [11] Ramazanzadeh, 2009, Emotional adjustment in infertile couples, Iran J Reprod Med
- cites [12] Brandes, 2009, When and why do subfertile couples discontinue their fertility care? A longitudinal cohort study in a secondary care subfertility population, Hum Reprod source
Classified as probably not a substantial claim. May combine two claims.
InterpretationreasoningThe MBPI can contribute to minimizing suffering and the negative consequences that infertility and its treatment trigger and help these patients to live a more vital, flexible, and values-based life and be less focused on infertility.
“The MBPI can contribute to minimizing suffering and the negative consequences that infertility and its treatment trigger and help these patients to live a more vital, flexible, and values-based life and be less focused on infertility.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataThe BDI showed a Cronbach alpha of .85 in the MBPI group and .91 in the control group.
“In this study we found a Cronbach alpha of .85 in the MBPI group and of .91 in the control group.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataThe DS showed a Cronbach alpha of .92 in the MBPI group and .96 in the control group.
“In the MBPI group, a Cronbach alpha of .92 was found, and in the control group it was .96.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataThe AAQ-II presented a Cronbach alpha of .85 in both groups.
“In the current study, the AAQ-II presented a Cronbach alpha of .85 in both groups.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataThe EE subscales presented a Cronbach alpha of .92 in both groups.
“In the current study, both subscales presented a Cronbach alpha of .92 in both groups.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataThe STAI-Y1 showed a Cronbach alpha of .93 in the MBPI group and .95 in the control group.
“The Cronbach alpha found for STAI-Y1 was .93 in the MBPI group and .95 in the control group.”
Quote in the paperNot a substantial claimMay combine two claims.
Study design and conductown dataThe groups did not present significant differences in demographics and were equivalent at baseline regarding the psychological measures used.
“Furthermore, the groups did not present significant differences in demographics and were equivalent at baseline regarding the psychological measures used.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
InterpretationreasoningParticipants recruited through the website of the Portuguese Fertility Association have Internet access and may be particularly informed and motivated to some kind of psychological intervention.
“Participants' recruitment was conducted through the website of the Portuguese Fertility Association, which means that they have Internet access and may be particularly informed and motivated to some kind of psychological intervention.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataThe SCS self-compassion subscale presented a Cronbach alpha of .92 in the MBPI group and .90 in the control group.
“The second corresponds to the sum of self-kindness, common humanity, and mindfulness and presented a Cronbach's alpha of .92 in the MBPI group and of .90 in the control group.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataThe ISE presented a Cronbach alpha of .95 in both the MBPI group and the control group.
“The ISE presented a Cronbach alpha of .95 in both the MBPI group and the control group.”
Quote in the paperNot a substantial claimMay combine two claims.
Interpretationown dataIncreasing mindfulness and acceptance skills, as well as cognitive decentering from thoughts and feelings, seem to help women to experience negative inner states in new ways, decreasing their entanglement with them and thus their psychological distress.
“Increasing mindfulness and acceptance skills, as well as cognitive decentering from thoughts and feelings, seem to help women to experience negative inner states in new ways, decreasing their entanglement with them and thus their psychological distress.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataThe SCS self-judgment subscale showed a Cronbach alpha of .90 in the MBPI group and .93 in the control group.
“The first one corresponds to the sum of self-criticism, isolation, and overidentification and showed a Cronbach alpha of .90 in the MBPI group and of .93 in the control group.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductnone givenThe attrition rate was low.
“The low attrition rate is also worth noting.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataThe FMI showed a Cronbach alpha of .77 (completed by a subgroup of 30 women in the MBPI group).
“In this study, the FMI showed a Cronbach alpha of .77(it was completed by a subgroup of 30 women in the MBPI group).”
Quote in the paperNot a substantial claimMay combine two claims.
Interpretationown dataThe perception of being in a struggle and getting defeated by infertility was lower in the MBPI group, and this may allow a broader perspective (e.g., other family-building options).
“The perception of being in a struggle and getting defeated by their infertility was also lower, and this may allow a broader perspective (e.g., other family-building options).”
Quote in the paperSubstantial claimMay combine two claims.
Study design and conductreasoningParticipants in both groups were medically assisted more or less in the same clinics, decreasing the probability of eventual influences of geographical differences.
“Since there are 10 public clinics and 16 private clinics in Portugal and they are fairly well distributed in the north, center, and south of the country, participants in both groups were medically assisted more or less in the same clinics, decreasing the probability of eventual influences of geographical differences.”
Quote in the paperSubstantial claimMay combine two claims.
Study design and conductnone givenParticipants showed equal interest in joining the program and shared similarities (primary infertility diagnosis, access to the Internet).
“Although it is not a randomized controlled trial, we emphasize that participants showed equal interest in joining the program and shared similarities (primary infertility diagnosis, access to the Internet).”
Quote in the paperSubstantial claimMay combine two claims.
Study design and conductcitationThe probability of systematic differences in comparison groups at baseline was low, diminishing the risk of selection bias.
“In general, the probability of systematic differences in comparison groups at baseline was low, diminishing the risk of selection bias (58).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [58] Deeks, 2003, Evaluating non-randomized intervention studies, Health Technol Assess source
May combine two claims.
InterpretationcitationDecentering from thoughts and observing them for what they are, merely thoughts and not necessarily corresponding to reality, is one of the skills trained during the MBPI, and this may be a crucial factor for the depressive symptoms reduction.
“Decentering from thoughts and observing them for what they are, merely thoughts and not necessarily corresponding to reality, is one of the skills trained during the MBPI, and this may be a crucial factor for the depressive symptoms reduction (49).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [49] Williams, 2007
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Rests on an assumption: Depressive symptoms are related to distorted thoughts about ourselves, and themes of worthlessness and self-blame are rather frequent.
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductreasoningThis was not a blind study.
“This was not a blind study given the nature of practical impediments to collecting the sample.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductnone givenThe recruitment procedure was exactly the same for the control group.
“However, since the recruitment procedure was exactly the same for the control group, this topic is less relevant.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataThe ESS showed a Cronbach alpha of .96 in the MBPI group and .95 in the control group.
“In this study, a Cronbach alpha of .96was found in the MBPI group and of .95 in the control group.”
Quote in the paperNot a substantial claimMay combine two claims.
InterpretationreasoningValues clarification and the use of metaphors and experiential exercises led MBPI participants to be less focused on their infertility problem and more able to engage in life.
“Values clarification (chosen life directions) and the use of metaphors and experiential exercises led them to be less focused on their infertility problem and more able to engage in life.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim.
Study design and conductown dataThe study is not a randomized controlled trial.
“Although it is not a randomized controlled trial, we emphasize that participants showed equal interest in joining the program and shared similarities (primary infertility diagnosis, access to the Internet).”
Quote in the paperSubstantial claimClassified as probably not a substantial claim.
Study design and conductnone givenParticipants in both groups were at different stages of their medical treatment and with various indications regarding the medical protocol to be followed, which can be confounders.
“Participants in both groups were at different stages of their medical treatment and with various indications regarding the medical protocol to be followed, which can be confounders.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataThe OAS showed a Cronbach alpha of .93 in both the MBPI group and the control group.
“A Cronbach alpha of .93 was found in both the MBPI group and the control group.”
Quote in the paperNot a substantial claim
The paper relies on this without support.
A mindfulness-based program specifically addressing infertility had not been developed until now.
“but to our knowledge a mindfulness-based program specifically addressing infertility has not been developed until now.”
The paper relies on this without support.
Depressive symptoms are related to distorted thoughts about ourselves, and themes of worthlessness and self-blame are rather frequent.
“Depressive symptoms are related to distorted thoughts about ourselves, and themes of worthlessness and selfblame are rather frequent.”
The paper relies on this without support.
No prior program focuses specifically on mindfulness and acceptance skills designed for people with infertility.
“To our knowledge, this is the first program that focuses specifically on mindfulness and acceptance skills designed for people with infertility, and we expect that its pioneering nature will stimulate the interest and curiosity of researchers and clinicians to extend its application.”
The paper relies on this without support.
The control group resembles a waiting list-type control group.
“In fact, it should be mentioned that our control group resembles a waiting list-type control group, and taking action to try to solve their infertility condition, contact with health care providers, having more information about the treatment itself, and developing expectations and hope about the possibility of being a biological mother may play an important role in the observed change (57).”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The MBPI was effective, showing a significant decrease in psychopathological symptoms and a significant improvement in emotion regulation processes compared with the control group.
“The MBPI was an effective intervention, with results showing a significant decrease in psychopathological symptoms and a significant improvement in emotion regulation processes (eg, mindfulness skills and self-efficacy to deal with infertility) compared with the control group.19”
From KindMap: an e-mental health tool to promote the well-being and mental health of people facing infertility - study protocol for a feasibility randomised control trial (2024) · cites this paper as [19]
The Results and Discussion report significant time-by-group effects for several psychopathological symptoms and for infertility-related self-efficacy, supporting those improvements compared with the control group. The Results report increased mindfulness skills only within a subgroup of MBPI participants, not as a comparison with controls. The claim therefore overextends the controlled comparison to mindfulness skills. (LLM, conf=0.86)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
Control-group entrapment scores are assigned to opposite subscales
MajorTable 4 puts the control scores near 4.7 under external entrapment and those near 8.2 under internal entrapment; Table 3 assigns those scores the other way around. This changes which control-group comparison belongs to each subscale.
“| ES external | 8.73 | 8.72 | 5.85 | 6.60 | 3.62 | .001 .20 | 4.73 | 5.64 | 4.84 | 5.98 | À.24 | .804 .00 | | | ES internal | 6.78 | 6.35 | 4.13 | 4.86 | 3.20 | .002 .16 | 8.24 | 8.52 | 8.05 | 9.18 | .25 | .813 .00 | |”
“| ES external | T1 | 8.73 | 8.72 | 8.24 | 8.52 | 7.08 | .009 .07 | .27 | .603 | .00 | 5.44 | .022 .06 | | | T2 | 5.85 | 6.60 | 8.05 | 9.18 | | | | | | | |”
Control-group defeat scores differ between results tables
MajorTable 4 gives control-group defeat means of 18.50 and 15.83 at T1 and T2, while Table 3 gives 18.24 and 17.59. The corresponding SDs also differ.
“| DS | 19.05 | 10.67 | 14.49 | 8.24 | 3.37 | .001 .17 | 18.50 | 12.15 | 15.83 | 10.10 | 1.02 | .323 .03 | |”
“| DS | T1 | 19.05 | 10.67 | 18.24 | 13.02 | 7.57 | .007 .08 | .27 | .606 | .00 | 4.27 | .042 .05 | | | T2 | 14.49 | 8.24 | 17.59 | 14.10 | | | | | | | |”
Current-treatment categories omit three control participants
MinorThe four current-treatment categories contain 34 control participants, but the control group has 37 participants. Three are unaccounted for in these categories.
Reported 37 · recomputed 34
“Current treatment | | | | | | | | | Assessment/waiting | 29 | 52.70 | 6 | 16.20 | 18.51 | < .001 | | | Ovarian stimulation | 2 | 3.60 | 7 | 18.90 | | | | | IVF | 12 | 21.80 | 9 | 24.30 | | | | | ICSI | 12 | 21.80 | 12 | 32.40 | | | |”
Mindfulness test uses degrees of freedom inconsistent with its subgroup size
MinorThe reported mindfulness analysis involved 30 women, for which a paired-samples t test would have 29 degrees of freedom, not 54.
“a significant increase [t(54) ¼ À4.24, P< .001,h 2 ¼ .38]”
“it was completed by a subgroup of 30 women in the MBPI group”
Self-compassion summary statistics differ between tables
MinorFor the same T1 groups, Table 3 reports an MBPI mean and SD of 39.70 and 8.90 and a control SD of 8.65; Table 2 instead reports 39.65, 8.82, and 9.29. These differences exceed rounding at the printed precision.
“| SCS comp | T1 | 39.70 | 8.90 | 41.24 | 8.65 | 1.23 | .271 .01 | .12 | .728 | .00 | 1.77 | .187 .02 |”
“| SCS compassion | 39.65 | 8.82 | 41.24 | 9.29 | À.83 | .409 | .008 |”
Demographic-equivalence claim conflicts with the reported age difference
MinorThe discussion says the groups had no significant demographic differences, whereas the results explicitly report an age difference and Table 1 gives its P value as .049.
“Furthermore, the groups did not present significant differences in demographics and were equivalent at baseline regarding the psychological measures used.”
“Age (y) | 34.87 | 4.20 | | 33.14 | 3.94 | 1.20 | .049 |”
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Cited by
Sorted by citations
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“C: 60 (60) (50%) RCT Counselling Other Individual 5 5 D: BDI”
BackgroundRockliff, H., Lightman, S. L., Rhidian, E., Buchanan, H., Gordon, U. D., & Vedhara, K. (2014) · Human Reproduction Update · doi:10.1093/humupd/dmu010 · Cited by 155 · see citing works
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“…2.443 .556 .004 Note: SCS ¼ self-compassion, DERS ¼ emotion regulation difficulties, FFMQ ¼ mindfulness. inconsistent with the study conducted by Galhardo et al. (Galhardo et al., 2013), which showed that women participated in the mindfulness-based program for infertility did not present…”
BackgroundInfluentialEvolution of psychology and counseling in infertility
Boivin, J., & Gameiro, S. (2015) · Fertility and Sterility · doi:10.1016/j.fertnstert.2015.05.035 · Cited by 94 · see citing works
Social support, self-efficacy, cognitive coping and psychological distress in infertile women
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“It helps infertile women to experience non-judgmental and objective view towards self to decrease depression and anxiety, as well as, to improve self-compassion and self-efficacy [16].”
BackgroundBai, C.-F., Cui, N.-X., Xu, X., Mi, G.-L., Sun, J.-W., Shao, D., Li, J., Jiang, Y.-Z., Yang, Q.-Q., Zhang, X., et al. (2019) · Human Reproduction · doi:10.1093/humrep/dez066 · Cited by 65 · see citing works
Preconception lifestyle advice for people with infertility
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“However, against this explanation is the finding of Galhardo et al. (2013) of significant decreases in OAS scores following a 10-week mindfulness-based programme, for participants whose baseline scores were lower than those of completers in our study.”
BackgroundResultInterventions to reduce shame: A systematic review
Goffnett, J., Liechty, J. M., & Kidder, E. (2020) · Journal of Behavioral and Cognitive Therapy · doi:10.1016/j.jbct.2020.03.001 · Cited by 66 · see citing works
Patel, A., Sharma, P. V. N., & Kumar, P. (2018) · Journal of Human Reproductive Sciences · doi:10.4103/jhrs.jhrs_41_18 · Cited by 57 · see citing works
Gaitzsch, H., Bénard, J., Hugon‐Rodin, J., Benzakour, L., & Streuli, I. (2020) · Archives of Women s Mental Health · doi:10.1007/s00737-019-01009-8 · Cited by 54 · see citing works
Luk, B. H.-K., & Loke, A. Y. (2015) · Journal of Sex & Marital Therapy · doi:10.1080/0092623x.2015.1074133 · Cited by 53 · see citing works
“Reductions in psychological stress among infertile women were also reported in two studies that used the ACT approach (Galhardo et al., 2013; Sherratt & Lunn, 2013) and in two other studies that used the BMS (Chan et al., 2006; Chan et al., 2012).”
BackgroundMethodResultInfluentialRole of religion, spirituality, and faith in assisted reproduction
Braga, D. P. D. A. F., Melamed, R. M. M., Setti, A. S., Zanetti, B. F., Figueira, R. D. C. S., Iaconelli, A., & Borges, E. (2018) · Journal of Psychosomatic Obstetrics & Gynecology · doi:10.1080/0167482x.2018.1470163 · Cited by 52 · see citing works
Mindfulness‐based program for stress reduction in infertile women: Randomized controlled trial
Nery, S. F., Paiva, S. P. C., Vieira, É. L., Barbosa, A. B., Sant'Anna, E. M., Casalechi, M., Dela Cruz, C., Teixeira, A. L., & Reis, F. M. (2019) · Stress and Health · doi:10.1002/smi.2839 · Cited by 50 · see citing works
Fard, T. R., Kalantarkousheh, S. M., & Faramarzi, M. (2018) · Middle East Fertility Society Journal · doi:10.1016/j.mefs.2018.06.001 · Cited by 52 · see citing works
Experiential avoidance, self-compassion, self-judgment and coping styles in infertility
Cunha, M., Galhardo, A., & Pinto-Gouveia, J. (2016) · Sexual & Reproductive Healthcare · doi:10.1016/j.srhc.2016.04.001 · Cited by 48 · see citing works
“In line with the current investigation, findings suggest that the Mindfulness Based Program for Infertility [56], Acceptance and Commitment Therapy [52] and Compassion-Focused Therapy [28] may be adequate approaches for patients dealing with infertility.”
ResultSelf-citationA prospective study using Hatha Yoga for stress reduction among women waiting for IVF treatment
Oron, G., Allnutt, E., Lackman, T., Sokal-Arnon, T., Holzer, H. E. G., & TAKEFMAN, J. E. (2015) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2015.01.011 · Cited by 45 · see citing works
Abedi Shargh, N., Bakhshani, N. M., Mohebbi, M. D., Mahmudian, K., Ahovan, M., Mokhtari, M., & Gangali, A. (2015) · Global Journal of Health Science · doi:10.5539/gjhs.v8n3p230 · Cited by 38 · see citing works
“In a research performed by Galhardo et al. (2013), results demonstrated that women participating in Mindfulness plans based on plans until its end, showed a meaningful decrease in depression, exterior and interior shame, being trapped and failure.”
ResultInfluentialHosseini, M., Mousavi, P., Hekmat, K., Haghighyzadeh, M. H., Fard, R. J., & Jafari, R. M. (2020) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2020.102403 · Cited by 34 · see citing works
Warne, E., Oxlad, M., & Best, T. (2023) · Health Psychology Review · doi:10.1080/17437199.2022.2058582 · Cited by 34 · see citing works
“…while employing formal and informal mindfulness practices, linked to fertility (Bai et al., 2019; Chan et al., 2006, 2012; Domar et al., 2011; Galhardo et al., 2013; Kalhori et al., 2020; Kim et al., 2014; Li et al., 2016; Psaros et al., 2015; Nery et al., 2019; Pasha et al., 2013; Paiva et…”
Psychological coping strategies associated with improved mental health in the context of infertility
Chernoff, A., Balsom, A. A., & Gordon, J. L. (2021) · Archives of Women s Mental Health · doi:10.1007/s00737-020-01029-9 · Cited by 32 · see citing works
“This finding is also consistent with research suggesting that mindfulness-based therapies are modestly beneficial for reducing depression and infertility distress among women struggling with infertility (Galhardo et al. 2013; Peterson and Eifert 2011; Shargh et al. 2015).”
ResultJensen, K. H. K., Krog, M. C., Koert, E., Hedegaard, S., Chonovitsch, M., Schmidt, L., Kolte, A. M., & Nielsen, H. S. (2021) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2021.04.018 · Cited by 33 · see citing works
“This is in line with current literature on the impact of meditation and mindfulness on psychological health for a broad range of individuals, including fertility patients, to help them cope with their problems (Baer et al., 2012; Bazarko et al., 2013; Beattie et al., 2017; de Vibe et al., 2013; Frederiksen et al., 201…”
BackgroundResultGolshani, F., Hasanpour, S., Mirghafourvand, M., & Esmaeilpour, K. (2021) · BMC Psychiatry · doi:10.1186/s12888-021-03283-2 · Cited by 34 · see citing works
Kalhori, F., Masoumi, S. Z., Shamsaei, F., Mohammadi, Y., & Yavangi, M. (2020) · Europe PMC (PubMed Central) · doi:10.22074/ijfs.2020.5785 · Cited by 29 · see citing works
“(22) consisted of 55 infertile women in the intervention group and 37 in the control group.”
BackgroundResultGalhardo, A., Alves, J., Moura-Ramos, M., & Cunha, M. (2020) · Journal of Reproductive and Infant Psychology · doi:10.1080/02646838.2019.1612046 · Cited by 31 · see citing works
Self-citationPatel, A., Sharma, P., & Kumar, P. (2018) · Journal of Human Reproductive Sciences · doi:10.4103/jhrs.jhrs_42_18 · Cited by 31 · see citing works
“[78,79] In addition to this, there are gaps in literature on the experiences of men resource‐constrained countries and its comparison with high‐income countries.[62,73] Literature from Indian contexts depicts that women experience social hardships, personal and sexual inadequacy, low self‐esteem, guilt, shame, loss of…”
BackgroundThe effect of yoga on stress level in infertile women
Kirca, N., & Pasinlioglu, T. (2019) · Perspectives in Psychiatric Care · doi:10.1111/ppc.12352 · Cited by 31 · see citing works
Interventions promoting mental health dimensions in infertile women: a systematic review
Koochaksaraei, F. Y., Simbar, M., Khoshnoodifar, M., Faramarzi, M., & Nasiri, M. (2023) · BMC Psychology · doi:10.1186/s40359-023-01285-1 · Cited by 29 · see citing works
“Galhardo et al. found a significant difference in the score of depression between the intervention and control groups after the intervention so that an increase in mindfulness skills, acceptance, and decentralization led to reduced mental distress in women with infertility [41].”
BackgroundResultApplication of Mindfulness-Based Psychological Interventions in Infertility
Patel, A., Sharma, P. V. N., & Kumar, P. (2020) · Journal of Human Reproductive Sciences · doi:10.4103/jhrs.jhrs_51_19 · Cited by 26 · see citing works
“Duration of treatments: The MBIs consist of one session per week and their duration may range from 8 to 12 weeks.[16-21] Therapy is preceded by a precourse orientation and assessment session to ensure patient suitability and willingness for the entire MBI module.”
BackgroundMethodInfluentialWang, G., Liu, X., & Lei, J. (2023) · Archives of Women s Mental Health · doi:10.1007/s00737-023-01307-2 · Cited by 26 · see citing works
Sahraian, K., Abdollahpour Ranjbar, H., Namavar Jahromi, B., Cheung, H. N., Ciarrochi, J., & Habibi Asgarabad, M. (2024) · BMC Psychiatry · doi:10.1186/s12888-023-05411-6 · Cited by 27 · see citing works
“According to research, self-compassion can serve as a psychological mechanism that reduces the influence of negative feelings like shame and self-blame on the emotional burden of infertility [53].”
BackgroundInfluentialJackson, P. L., Saunders, P., Mizzi, S., & Hallam, K. T. (2025) · BMC Women s Health · doi:10.1186/s12905-025-04054-x · Cited by 27 · see citing works
The infertility trap: how defeat and entrapment affect depressive symptoms
Galhardo, A. B., Moura‐Ramos, M., Cunha, M. I. V. A., & Pinto‐Gouveia, J. (2015) · Human Reproduction · doi:10.1093/humrep/dev311 · Cited by 25 · see citing works
“Accordingly, our findings suggest that contextual cognitive-behavioral therapies that clearly address emotion regulation skills, for example, the MindfulnessBased Program for Infertility (Galhardo et al., 2013b), Acceptance and Commitment Therapy (Hayes et al., 1999) and Compassion-Focused Therapy (Gilbert, 2010) may…”
BackgroundResultInfluentialSelf-citationSelf-compassion training and psychological well-being of infertile female
Afshani, S. A., Abooei, A., & Abdoli, A. M. (2019) · International Journal of Reproductive BioMedicine (IJRM) · doi:10.18502/ijrm.v17i10.5300 · Cited by 23 · see citing works
“The results of mentioned study showed the importance of positive psychology in comparison with damage-based psychology (13).”
ResultGalhardo, A., Cunha, M., & Pinto‐Gouveia, J. (2019) · Clinical Psychology & Psychotherapy · doi:10.1002/cpp.2362 · Cited by 22 · see citing works
Self-citationLi, J., Hong, L., & Long, L. (2018) · Nursing Open · doi:10.1002/nop2.232 · Cited by 17 · see citing works
How Does the Mindfulness-Based Program for Infertility (MBPI) Work in Reducing Depressive Symptoms?
Galhardo, A. B., Moura‐Ramos, M., Cunha, M. I. V. A., & Pinto‐Gouveia, J. (2017) · Mindfulness · doi:10.1007/s12671-017-0805-z · Cited by 16 · see citing works
Self-citationJudit Szigeti, F., Kazinczi, C., Szabó, G., Sipos, M., Ujma, P. P., & Purebl, G. (2024) · Human Reproduction · doi:10.1093/humrep/deae119 · Cited by 16 · see citing works
“Mind-body methods include, among others, the Mind/Body Program for Infertility (MBPI) (Domar et al. , 1990), the Integrative Body-Mind-Spirit programme (Chan et al. , 2006, 2012), and mindfulness-based interventions (Galhardo et al. , 2013; Nery et al. , 2019; Mousavi et al. , 2020).”
MethodMasoumi, S. Z., Parsa, P., Kalhori, F., Mohagheghi, H., & Mohammadi, Y. (2019) · Iranian Journal of Psychiatry · doi:10.18502/ijps.v14i2.996 · Cited by 16 · see citing works
“forms; and (8) cultural and language adaptations”
BackgroundInfluentialCan lifestyle changes significantly improve male fertility: A narrative review?
Böcü, K., Boeri, L., Mahmutoglu, A. M., & Vogiatzi, P. (2024) · Arab Journal of Urology · doi:10.1080/20905998.2024.2421626 · Cited by 16 · see citing works
“Mindfulness interventions can boost self-compassion, emotion regulation, and coping strategies, positively affecting quality of life and pregnancy rates [98].”
Njogu, A. N., Kaburu, F., Njogu, J. N., Barasa, E., Mutisya, A. K., & Luo, Y. (2023) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-023-02771-6 · Cited by 17 · see citing works
“Anxiety and depressive symptoms are related to distorted thoughts about oneself, others, and the future, and the themes of worthlessness, shame, self-criticism, and rumination [43].”
BackgroundThe Effects of Yoga on Pregnancy, Stress, and Anxiety in Infertile Individuals
YILDIRIM, A. D., & Satılmış, İ. G. (2022) · Holistic Nursing Practice · doi:10.1097/hnp.0000000000000543 · Cited by 15 · see citing works
Bradford, A. M., & Woodard, T. L. (2016) · Journal of Adolescent and Young Adult Oncology · doi:10.1089/jayao.2016.0066 · Cited by 15 · see citing works
Impact of a Structured Yoga Program on Anxiety in Infertility Patients: A Feasibility Study
Jasani, S., & Heller, B. (2016) · Journal of Fertilization In Vitro - IVF-Worldwide Reproductive Medicine Genetics & Stem Cell Biology · doi:10.4172/2375-4508.1000183 · Cited by 14 · see citing works
Effect of cognitive behavioral therapy on anxiety and depression of infertile women: A meta–analysis
Nikniaz, L., Abdolahi, H., Ghojazadeh, M., Abdi, S., Farhangi, M., & Nikniaz, Z. (2019) · Asian Pacific Journal of Reproduction · doi:10.4103/2305-0500.270102 · Cited by 13 · see citing works
Li, J., Liu, B., & Li, M. (2014) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000000091 · Cited by 13 · see citing works
Galhardo, A., Cunha, M., Monteiro, B., & Pinto-Gouveia, J. (2020) · Journal of Contextual Behavioral Science · doi:10.1016/j.jcbs.2020.09.006 · Cited by 11 · see citing works
Self-citationThe Experience of Infertility: An Unexpected Barrier in the Transition to Parenthood
Peterson, B. D., & Place, J. M. (2019) · Springer eBooks · doi:10.1007/978-3-030-24864-2_2 · Cited by 10 · see citing works
Deshpande, S., Patel, K. D., Parulkar, T., Mahabalesh, K., Madhusudhan, P., Madhusudhan, D. K., & Thimmapuram, J. (2023) · Journal of Ayurveda and Integrative Medicine · doi:10.1016/j.jaim.2023.100793 · Cited by 8 · see citing works
Supporting the treatment of infertility using psychological methods
Humeniuk, E., Pucek, W., Wdowiak, A., Filip, M., Bojar, I., & Wdowiak, A. (2023) · Annals of Agricultural and Environmental Medicine · doi:10.26444/aaem/171874 · Cited by 10 · see citing works
“After its application, a significant decrease was observed in the symptoms of depression, internal and external shame, and sense of failure [35].”
BackgroundMindfulness improves the mental health of infertile women: A systematic review
Kundarti, F. I., Titisari, I., Rahayu, D. E., Kiswati, K., & Jamhariyah (2023) · Journal of Public Health Research · doi:10.1177/22799036231196693 · Cited by 9 · see citing works
“9,21,22,51 Mindfulness has been successful in reducing depression rates by up to 48% 22 Mindfulness can affect how the brain processes emotions under stress, shift activation in some regions of the prefrontal cortex from right-sided activation to left-sided activation in more excellent emotional…”
BackgroundYANIK, D., & Budak, F. K. (2022) · Journal of the American Psychiatric Nurses Association · doi:10.1177/10783903221122801 · Cited by 9 · see citing works
“…effectiveness of an awareness-based stress reduction program, it was determined that through a 10-week awareness-based stress reduction program, infertile women’s depression and internal and external embarrassment decreased and their self-efficacy and awareness increased (Galhardo et al., 2013).”
BackgroundWang, X., & Wang, Y. (2022) · Journal of Sex & Marital Therapy · doi:10.1080/0092623x.2022.2109542 · Cited by 8 · see citing works
“Self-compassion has been described in two studies (Galhardo et al., 2013; Li et al., 2016).”
BackgroundMethodInfluentialDembińska, A. (2019) · Psychiatria i Psychologia Kliniczna · doi:10.15557/pipk.2019.0032 · Cited by 8 · see citing works
“…to offer help for depression, which underlies the of acceptance, by using other mindfulness techniques (Abedi Shargh et al., 2015; Dembińska, 2016; Galhardo et al., 2013a; Li et al., 2016; Sherratt and Lunn, 2013), and by providing information about health condition, treatment perspectives and…”
BackgroundMethodInfluentialZhi, L., Mireyi, J., Maierhaba, A., Xu, H., He, L., & Lizha, J. (2025) · PLoS ONE · doi:10.1371/journal.pone.0321877 · Cited by 8 · see citing works
“Many foreign and domestic experts and scholars have confirmed that mindfulness training is conducive to improving physical and mental health [16,29–32].”
Asazawa, K., Jitsuzaki, M., Mori, A., & Ichikawa, T. (2023) · Japan Journal of Nursing Science · doi:10.1111/jjns.12536 · Cited by 7 · see citing works
Boedt, T., Willaert, N., Fong, S. L., Dancet, E. A. F., Spiessens, C., Raes, F., Matthys, C., & der Gucht, K. V. (2022) · BMJ Open · doi:10.1136/bmjopen-2021-050088 · Cited by 7 · see citing works
Schuette, S. A., Andrade, F. C., Woodward, J. T., & Smoski, M. J. (2023) · Journal of Health Psychology · doi:10.1177/13591053231185549 · Cited by 7 · see citing works
“Galhardo et al. (2013a) conducted a mindfulness-based intervention in women with infertility which incorporated metaphors and experiential exercises derived from ACT.”
BackgroundMethodResultInfluentialÖzcan, Ş., & Kırca, N. (2021) · Health Care For Women International · doi:10.1080/07399332.2021.2007927 · Cited by 6 · see citing works
“In the infertility treatment process, it has been determined that providing counseling services to women, encouraging them to take part in support group sessions (Galhardo et al., 2013), and applying mind-body relaxation strategies are highly effective on women’s quality of life.”
Backgroundİnfertilitede Kullanılan Geleneksel ve Tamamlayıcı Tıp Uygulamaları
SOYİÇ, Y., & ÖZKAN, F. S. (2020) · Ordu Üniversitesi Hemşirelik Çalışmaları Dergisi · doi:10.38108/ouhcd.747957 · Cited by 6 · see citing works
“Sonuç olarak; infertilite yaşayan kadınlarda bilinçli etkinlik programının anlamlı etkinliği olduğu görülmüştür (Galhardo et al., 2013).”
Martínez‐Borba, V., Lorente-Debón, B., & Osma, J. (2025) · Telemedicine Journal and e-Health · doi:10.1089/tmj.2024.0446 · Cited by 5 · see citing works
“TELEMEDICINE and e-HEALTH 563 depression, anxiety, stress, quality of life, and emotion dysregulation 30,31,40 even when combined with positive reappraisal interventions.”
Li, C., Fan, Y., Chen, D., Wu, Y., Huang, Y., & Liu, D. (2024) · Psychology and Health · doi:10.1080/08870446.2024.2387213 · Cited by 5 · see citing works
“…this study, the defeat measurements for the IVF-ET couples were 25.19 for the husband and 27.18 for the wife, which was higher than the findings of galhardo et al. (2013) on 55 infertile patients, indicating that the defeat level of IVF-ET couples in China was high with a certain degree of…”
InfluentialEspinosa, A., Rodolfo Morrison, J., González, D., Jamardo, J., Fortuna, F., Paz-Díaz, C., Monclus, P. G., Frías, C., Soto, P., González, A., et al. (2022) · Occupational Therapy International · doi:10.1155/2022/2174397 · Cited by 6 · see citing works
Menurunkan Infertility-Related Stres dengan Program Mindfulness Based Stress Reduction (MBSR)
Retnoningtias, D. W., & Hardika, I. R. (2021) · JIP (Jurnal Intervensi Psikologi) · doi:10.20885/intervensipsikologi.vol13.iss1.art6 · Cited by 5 · see citing works
Chan, C. H. Y., Lau, B. H. P., Wong, Q. S., Tam, M. Y. J., So, G. Y. K., Leung, H. T., Fung, Y. L., Chan, C., Li, R., & Ng, E. H. Y. (2019) · Asia Pacific Journal of Social Work and Development · doi:10.1080/02185385.2019.1578684 · Cited by 5 · see citing works
Sharing good practice in sport and exercise psychology
McCormick, A., Coyle, M., & Gibbs-Nicholls, S. (2018) · Sport & Exercise Psychology Review · doi:10.53841/bpssepr.2018.14.1.47 · Cited by 5 · see citing works
Zhang, X., Wang, J., Wang, Y., Wang, J., & Luo, F. (2024) · PsyCh Journal · doi:10.1002/pchj.817 · Cited by 6 · see citing works
“There have also been experimental studies validating the impact of mindfulness on shame in clinical interventions (Galhardo, Cunha, and Pinto-Gouveia 2013; Goldsmith et al. 2014; Proeve, Anton, and Kenny 2018; Westerman, McCann, and Sparkes 2020; Oren-Schwartz et al. 2022).”
Pandya, S. (2023) · Women's Reproductive Health · doi:10.1080/23293691.2023.2206400 · Cited by 5 · see citing works
Incorporating Mindfulness Practice for Better Performance in Work and Daily Life
Urcola‐Pardo, F. (2023) · Integrated science · doi:10.1007/978-3-031-15959-6_16 · Cited by 4 · see citing works
Asadabad, R. A., Imani, S., Fathabadi, J., Noroozi, A., & Alizadehgoradel, J. (2022) · international journal high risk behaviors & addiction · doi:10.5812/ijhrba.117042 · Cited by 4 · see citing works
“This finding is consistent with previous studies (12, 18-23).”
ResultRodolfo Morrison, J., Paz-Díaz, C., Monclus, P. G., Frías, C., Espinosa, A., Soto, P., González, A., Díaz, S. M., & López, I. A. (2020) · Revista de la Facultad de Medicina · doi:10.15446/revfacmed.v68n4.77122 · Cited by 4 · see citing works
Psychological Aspects of Infertility
Zweifel, J. E., & Lawson, A. K. (2020) · Springer eBooks · doi:10.1007/978-981-15-2377-9_66 · Cited by 4 · see citing works
Xu, Q., Wan, Z., Xiong, Z., Zhu, X., Han, Q., Wang, Y., Zhao, J., & Yu, F. (2025) · BMC Women s Health · doi:10.1186/s12905-025-04146-8 · Cited by 3 · see citing works
“Among ART procedures, IVF and ovarian stimulation are particularly anxiety-pro-voking for patients [14–18].”
InfluentialKaptein, A. A., Harper, J. C., van den Dool, G., Schoonenberg, M. P. G., Smeenk, J. M. J., Daneshpour, H., Troost, M., van Wijk, L. M., Tielen, N., Smit, E., et al. (2024) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2024.104113 · Cited by 3 · see citing works
İnfertil Kadınların Öz Şefkat, Bilinçli Farkındalık ve Ruhsal Sağlıkları Arasındaki İlişki
PALAZOĞLU, N., & Karaca, A. (2024) · Sağlık Bilimlerinde Değer · doi:10.33631/sabd.1232941 · Cited by 3 · see citing works
Tardin, R. M. M., Martínez, P. A., Bonow, M. P., & Schuffner, A. G. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-818309-0.00001-0 · Cited by 3 · see citing works
MINDFULNESS CONTRIBUTIONS ON MEDICAL CONDITIONS: A LITERATURE REVIEW
Mouzinho, L. S. N., Costa, N., Alves, T., Silva, S., & de Lima, L. (2018) · Psicologia Saúde & Doenças · doi:10.15309/18psd190202 · Cited by 3 · see citing works
Carolino, N., Cunha, M., Pinto-Gouveia, J., Gameiro, S., & Galhardo, A. (2024) · BMJ Open · doi:10.1136/bmjopen-2024-087447 · Cited by 3 · see citing works
“19 Furthermore, participants in the MBPI group continued to reveal therapeutic benefits at a 6-month follow-up and experienced lasting results for up to 7 years.”
Self-citationPsychological Intervention in Depression, Anxiety, and Stress Among Infertile Women: a Meta-analysis
Tomy, T., & Vinod Kumar, S. (2023) · Trends in Psychology · doi:10.1007/s43076-023-00351-2 · Cited by 2 · see citing works
“3) clearly shows that the effect size of individual studies varied from 0.403 (Valoriani et al., 2014) to 3.371 (Galhardo et al., 2013).”
InfluentialIntegration of Motivational Interviewing with Mindfulness and Other Integrative Health Modalities
Stephens, J. J., & Gold, M. A. (2023) · doi:10.1093/med/9780197583876.003.0019 · Cited by 2 · see citing works
Effect of Mindfulness-based Interventions on Mental Health of Women with Infertility
Dalal, S. (2023) · Journal of Applied Consciousness Studies · doi:10.4103/jacs.jacs_37_23 · Cited by 2 · see citing works
Relationship of Self-Compassion with Anxiety and Depressive Symptoms in Infertile Women
Aygün, E. G., Sancak, B., & Özer, Ü. (2022) · Acibadem Universitesi Saglik Bilimleri Dergisi · doi:10.31067/acusaglik.1050692 · Cited by 5 · see citing works
Cardoso, B., Galhardo, A. B., Massano‐Cardoso, I., & Cunha, M. I. V. A. (2021) · Revista Portuguesa de Investigação Comportamental e Social · doi:10.31211/rpics.2021.7.2.220 · Cited by 2 · see citing works
Self-citationHinkle, M., & Dodd, J. (2021) · Journal of Sex & Marital Therapy · doi:10.1080/0092623x.2021.1974623 · Cited by 3 · see citing works
Hahn, C. K., Caraway, J., Hansen, K. S., & Ranum, E. (2019) · Human Fertility · doi:10.1080/14647273.2019.1593517 · Cited by 2 · see citing works
ASSESSMENT OF SOCIO-DEMOGRAPHIC CHARACTERISTICS AND SELF-ESTEEM AMONG INFERTILE MALES
Ali, E. E. K., El-hameed, N. A. E.-G. A., & Abdullah, S. O. (2019) · The Malaysian Journal of Nursing · doi:10.31674/mjn.2019.v10i04.010 · Cited by 2 · see citing works
Park, S. A., & Kim, H. (2026) · medRxiv · doi:10.64898/2026.02.26.26347155 · Cited by 1 · see citing works
Psychological and cognitive-emotional moderators of suicidal ideation and self-harm in young adults
Dickhoff, J., Deng, W., Aleman, A., Vries, V. E. D., Opmeer, E. M., & van Tol, M. (2026) · Scientific Reports · doi:10.1038/s41598-026-37127-4 · Cited by 1 · see citing works
“Previous studies found mindfulness as well as self-compassion to link to suicidal ideation, self-harm and other risk factors (such as depression severity or thwarted belongingness) for suicide 31,33,37,41,45,79–81 .”
Ciacchini, R., Piarulli, A., Bottai, B., Orrù, G., Gemignani, A., & Conversano, C. (2025) · Psychology International · doi:10.3390/psycholint7030063 · Cited by 3 · see citing works
“…emotional regulation, improve communication, and strengthen relational well-being—factors that may contribute to better psychological outcomes and indirectly support treatment adherence and success (Galhardo et al., 2013; Patel et al., 2020; Massaro, 2021; Kundarti et al., 2023; Wang et al., 2023).”
Zhang, X., Wang, J., Wang, Y., et al. (2024) · Research Square · doi:10.21203/rs.3.rs-4217802/v1 · Cited by 1 · see citing works
Fatehi, N., hosnaroudi, M. G., & Abed, N. (2021) · مجله علمی دانشگاه علوم پزشکی رفسنجان · doi:10.52547/jrums.20.6.660 · Cited by 5 · see citing works
Depression, Anxiety and Marital Satisfaction among Infertile Males at Assiut Universal Hospital
Hameed, N., & Thabet, R. A. (2021) · Egyptian Journal of Health Care · doi:10.21608/ejhc.2021.198474 · Cited by 1 · see citing works
The Relationship of Two Types of Shame with Meditation Experience
Proeve, M. J. (2020) · Mindfulness · doi:10.1007/s12671-020-01489-1 · Cited by 1 · see citing works
“Galhardo et al. (2013) found that a mixed-approach, mindfulness-based program for women who experienced infertility, based onMBSR and principles of ACT, decreased internal and external shame at post-treatment.”
BackgroundResultPsychosocial aspects of therapeutic donor insemination
Patel, A., Sharma, P., & Kumar, P. (2018) · Journal of Human Reproductive Sciences · doi:10.4103/jhrs.jhrs_108_18 · Cited by 1 · see citing works
Nutrition and Integrative Approaches to Infertility: Improving Patient Experience and Outcomes
Bold, J. (2017) · Worcester Research and Publications (University of Worcester) · Cited by 1 · see citing works
Comparison of Psychological Aspects of Infertile & Fertile Males.
Abdullah, S. O., Ali, E. E. K., & El-hameed, N. A. E.-G. A. (2017) · Assiut Scientific Nursing Journal · doi:10.21608/asnj.2017.67586 · Cited by 1 · see citing works
Sun, H., Gao, X., Zhang, J., & Qin, R. (2026) · Current Urology · doi:10.1097/cu9.0000000000000366 · Cited by 1 · see citing works
Othman, S. M. E., Javanmard, M., Roberts, L., Conlon, L., & Steen, M. (2026) · Cogent Mental Health · doi:10.1080/28324765.2026.2711571
“…a university research unit, reproductive sciences institute, fertility medical centre within hospital obstetrics and gynaecology outpatient clinics (Afshani et al., 2019; Galhardo et al., 2013a; Li et al., 2016; Njogu et al., 2023; Rezapour-Mirsaleh et al., 2020, 2024; Sahraian et al., 2024).”
InfluentialPutra, M. A. D. T., Endratamma, M. A., Akbar, M. F., Hamid, A. A., & Mokhtar, M. H. (2026) · Medicina · doi:10.3390/medicina62071335
“Galhardo et al. demonstrated that mindfulness training enhanced fertility-related quality of life and reduced distress symptoms, underscoring the potential of these approaches to address infertility-specific stressors [27].”
Park, S. A., & Kim, H. (2026) · Research Square · doi:10.21203/rs.3.rs-9279355/v1
- Authors
- Galhardo, A., Cunha, M., & Pinto-Gouveia, J.
- Affiliations
- Instituto Superior Miguel Torga (PT)
- Corresponding author
- Galhardo, Ana
- Venue
- Fertility and Sterility
- Publisher
- Elsevier BV
- Published
- 2013-10
- Volume
- 100
- Issue
- 4
- Pages
- 1059-1067
- ISSN
- 0015-0282 (ISSN-L)
- OpenAlex
- W1994072477
- Cited by
- 120
- References
- 57
- Citations by year
- 2026: 12 · 2025: 11 · 2024: 8 · 2023: 16 · 2022: 9 · 2021: 10 · 2020: 12 · 2019: 13 · 2018: 11 · 2017: 3 · 2016: 3 · 2015: 10 · 2014: 2
- FWCI
- 5.56
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Fertility and Sterility (publishedVersion)
- PubMed (publishedVersion)
- Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) (submittedVersion, other-oa)
- Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) (submittedVersion)
- Funders
- Fundação para a Ciência e a Tecnologia
- Topics
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Keywords
- infertility, mindfulness-based interventions, depression, shame, entrapment, defeat, self-compassion, experiential avoidance, acceptance, psychological distress, women with infertility
- MeSH terms
- Adult, Analysis of Variance, Awareness, Breathing Exercises, Cognition, Depression, Female, Fertility, Humans, Infertility, Female, Male, Mental Health, Perception, Portugal, Psychophysiology, Psychotherapy, Group, Surveys and Questionnaires, Self Concept, Shame, Stress, Psychological, Time Factors, Chi-Square Distribution, Treatment Outcome, Imagery, Psychotherapy, Meditation, Mind-Body Therapies
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Claims read by deepseek-v4.1-flash under definition version 3 (extract-v3) on 2026-10-11.
Classified by jev-1.13-20260917 (gold-guideline-v0.2) on 2026-10-11.
Cited sources are checked by gpt-6-sol.
Statistics and arithmetic are recomputed, not judged.
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