CoChat
Sign Up
Cited by 131Nursing care and researchCancer survivorship and careMobile Health and mHealth Applications

The DOI matches its Crossref record; 51 of the 51 references it cites were found in a registry or an index.

The effectiveness of e-Health interventions on caregiver burden, depression, and quality of life in informal caregivers of patients with cancer: A systematic review and meta-analysis of randomized controlled trials

Li, Yunhuan, Li, Juejin, Zhang, Yalin, Ding, Yuxin, Hu, Xiaolin·2022·International Journal of Nursing Studies
DOI 10.1016/j.ijnurstu.2022.104179
Open this paper in CoChat — free account

Abstract

Background With the increasing incidence and survival rate of cancer, there are more people living with cancer, which increases the responsibilities of informal caregivers and results in a significant caregiver burden, depression, and low quality of life. The efficacy of e-Health interventions has already been proven in decreasing caregiver burden, addressing psychosocial concerns, and increasing quality of life among caregivers of patients with chronic diseases. However, the utilization of e-Health interventions on the informal caregivers of cancer patients is still limited and the effectiveness is unclear.Objectives To assess the impact of e-Health interventions on the caregiver burden, depression, and quality of life of informal caregivers of cancer patients.Methods A literature search was conducted in six electronic databases (PubMed, EMBASE, Web of Science, CENTRAL, PsycInfo, and CINAHL Plus with Full Text) from the inception of the databases to 31 May 2021. Two authors independently screened the studies and extracted the data. Cochrane's bias risk tool for randomized controlled trials was used to examine the methodological quality of the included studies. The intervention effect was estimated by calculating the standard mean difference (SMD) and 95% confidence interval (CI) with Review Manager 5.3. A sensitivity analysis was conducted to test the robustness of the pooled results.Results Seven randomized controlled trials with 326 participants were included in the review. The results of the meta-analysis showed that e-Health interventions could significantly improve the depression (SMD = -0.90, 95% CI [-1.76∼-0.04], P = 0.04) and quality of life (SMD = 0.45, 95% CI [0.13∼0.77], P = 0.006), but not caregiver burden (SMD = -0.29, 95% CI [-0.61∼0.02], P = 0.07) in informal caregivers. Sensitivity analysis showed that only the caregiver burden was stable.Conclusion e-Health interventions are a convenient method to support the informal caregivers of cancer patients, and can mitigate depression and enhance the quality of life of informal caregivers, but had no significant effect on easing the caregiver burden. In future, tailored e-Health intervention, based on informal caregivers' demographic characteristics and cultural context, is warranted to improve informal caregivers' well-being.Registration number CRD42021250253 (PROSPERO).

Overview

Integrity signals

Registry

Crossref · 10.1016/j.ijnurstu.2022.104179

Cites

51 of 51 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Show all 51 references

Cited by

Sorted by citations

Related

See all

Metadata

Authors
Li, Y., Li, J., Zhang, Y., Ding, Y., & Hu, X.
Affiliations
Sichuan University (CN)
Corresponding author
Hu, Xiaolin
ORCID
Venue
International Journal of Nursing Studies
Publisher
Elsevier BV
Published
2022-03
Volume
127
Pages
104179
ISSN
0020-7489 (ISSN-L)
DOI
10.1016/j.ijnurstu.2022.104179
OpenAlex
W4206107020
Cited by
130
References
51
Citations by year
2026: 30 · 2025: 36 · 2024: 37 · 2023: 19 · 2022: 8
FWCI
5.60
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • International Journal of Nursing Studies (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Sichuan University West China Hospital
  • National Natural Science Foundation of China (82172842, 81803104)
  • Sichuan University (2020HXBH119)
  • Science and Technology Department of Sichuan Province (2022SYSX0064)
  • National Key Research and Development Program of China (2021YFE0206600)
Topics
  • Health Sciences › Nursing › Research and Theory › Nursing care and research
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
  • Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
Keywords
digital health interventions, informal caregivers, caregiver burden, depression, quality of life, cancer patients, caregiver well-being
MeSH terms
Caregiver Burden, Depression, Humans, Neoplasms, Quality of Life, Randomized Controlled Trials as Topic, Caregivers, Telemedicine

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review