Origin and Functions of Tissue Macrophages

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

Polazzi, E., Mengoni, I., Caprini, M., Peña‐Altamira, E., Kurtys, E., & Monti, B. (2012) · Neurosignals · doi:10.1159/000337115 · Cited by 9,023

Macrophage activation and polarization: nomenclature and experimental guidelines

Murray, P. J., Allen, J. E., Biswas, S. K., Fisher, E. A., Gilroy, D. W., Goerdt, S., Gordon, S., Hamilton, J. A., Ivashkiv, L. B., Lawrence, T., et al. (2014) · Immunity · doi:10.1016/j.immuni.2014.06.008 · Cited by 6,337

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

Ginhoux, F., Greter, M., Leboeuf, M., Nandi, S., See, P., Gokhan, S., Mehler, M. F., Conway, S. J., Ng, L. G., Stanley, E. R., et al. (2010) · Science · doi:10.1126/science.1194637 · Cited by 5,175

Macrophage biology in development, homeostasis and disease

Wynn, T. A., Chawla, A., & Pollard, J. W. (2013) · Nature · doi:10.1038/nature12034 · Cited by 4,684 · cited 1×

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

Paolicelli, R. C., Bolasco, G., Pagani, F., Maggi, L., Scianni, M., Panzanelli, P., Giustetto, M., Ferreira, T. A., Guiducci, E., Dumas, L., et al. (2011) · Science · doi:10.1126/science.1202529 · Cited by 4,244

The Classical Complement Cascade Mediates CNS Synapse Elimination

Stevens, B., Allen, N. J., Vazquez, L. E., Howell, G. R., Christopherson, K. S., Nouri, N., Micheva, K. D., Mehalow, A. K., Huberman, A. D., Stafford, B., et al. (2007) · Cell · doi:10.1016/j.cell.2007.10.036 · Cited by 3,313

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

Yona, S., Kim, K.-W., Wolf, Y., Mildner, A., Varol, D., Breker, M., Strauss-Ayali, D., Viukov, S., Guilliams, M., Misharin, A., et al. (2013) · Immunity · doi:10.1016/j.immuni.2012.12.001 · Cited by 3,245

TREM2 Variants in Alzheimer's Disease

Guerreiro, R., Wojtas, A., Bras, J., Carrasquillo, M., Rogaeva, E., Majounie, E., Cruchaga, C., Sassi, C., Kauwe, J. S. K., Younkin, S., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1211851 · Cited by 3,020

Analysis of Fractalkine Receptor CX3CR1 Function by Targeted Deletion and Green Fluorescent Protein Reporter Gene Insertion

Jung, S., Aliberti, J., Graemmel, P., Sunshine, M. J., Kreutzberg, G. W., Sher, A., & Littman, D. R. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.11.4106-4114.2000 · Cited by 2,632

Microglia promote learning-dependent synapse formation through brain-derived neurotrophic factor

Parkhurst, C. N., Yang, G., Ninan, I., Savas, J. N., Yates, J. R., Lafaille, J. J., Hempstead, B. L., Littman, D. R., & Gan, W.-B. (2013) · Cell · doi:10.1016/j.cell.2013.11.030 · Cited by 2,599

TB drug development: immunology at the table

Nathan, C., & Barry, C. E. (2015) · Immunological Reviews · doi:10.1111/imr.12275 · Cited by 45

Sialic acid-conjugate modified doxorubicin nanoplatform for treating neutrophil-related inflammation

Wang, S., Lai, X., Li, C., Chen, M., Hu, M., Liu, X., Song, Y., & Deng, Y. (2021) · Journal of Controlled Release · doi:10.1016/j.jconrel.2021.07.044 · Cited by 45

Tumor associated macrophage in HPV+ tumors: Between immunosuppression and inflammation

Gorvel, L., & Olive, D. (2022) · Seminars in Immunology · doi:10.1016/j.smim.2022.101671 · Cited by 44

Elucidation of monocyte/macrophage dynamics and function by intravital imaging

Rua, R., & McGavern, D. B. (2015) · Journal of Leukocyte Biology · doi:10.1189/jlb.4ri0115-006rr · Cited by 46

A new and efficient culture method for porcine bone marrow-derived M1- and M2-polarized macrophages

Gao, J., Scheenstra, M. R., van Dijk, A. I. J. M., Veldhuizen, E. J. A., & Haagsman, H. P. (2018) · Veterinary Immunology and Immunopathology · doi:10.1016/j.vetimm.2018.04.002 · Cited by 50

Cardiomyocytes and Macrophages Discourse on the Method to Govern Cardiac Repair

Gomez, I., Duval, V., & Silvestre, J. (2018) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2018.00134 · Cited by 49

Characterization of Subpopulations of Chicken Mononuclear Phagocytes That Express TIM4 and CSF1R

Hu, T., Wu, Z., Bush, S. J., Freem, L. J., Vervelde, L., SUMMERS, K. M., Balic, A., Hume, D. A., & Kaiser, P. (2019) · The Journal of Immunology · doi:10.4049/jimmunol.1800504 · Cited by 49

Immune mechanisms of stress susceptibility and resilience: Lessons from animal models

Tsyglakova, M., McDaniel, D. K., & Hodes, G. E. (2019) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2019.100771 · Cited by 46

Immune and vascular contributions to organogenesis of the testis and ovary

Gu, X., Li, S., & DeFalco, T. (2021) · FEBS Journal · doi:10.1111/febs.15848 · Cited by 45

Critical Adverse Impact of IL-6 in Acute Pneumovirus Infection

Percopo, C. M., Ma, M., Brenner, T. A., Krumholz, J. O., Break, T. J., Laky, K., & Rosenberg, H. F. (2018) · The Journal of Immunology · doi:10.4049/jimmunol.1800927 · Cited by 43

Lamin A/C and the Immune System: One Intermediate Filament, Many Faces

Saéz, Á., Herrero‐Fernández, B., Gómez-Bris, R., Somovilla-Crespo, B., Rius, C., & González, J. M. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21176109 · Cited by 43

Macrophage-Derived TGF-β and VEGF Promote the Progression of Trauma-Induced Heterotopic Ossification

Tu, B., Li, J., Sun, Z., Zhang, T., Liu, H., Yuan, F., & Fan, C. (2022) · Inflammation · doi:10.1007/s10753-022-01723-z · Cited by 43

Immunosenescence and Aging: Neuroinflammation Is a Prominent Feature of Alzheimer’s Disease and Is a Likely Contributor to Neurodegenerative Disease Pathogenesis

Bowirrat, A. (2022) · Journal of Personalized Medicine · doi:10.3390/jpm12111817 · Cited by 46

Markers of the ageing macrophage: a systematic review and meta-analysis

Moss, C. E., Phipps, H., Wilson, H. L., & Kiss‐Toth, E. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1222308 · Cited by 42

Insight into the role of macrophages in periodontitis restoration and development

Mo, K., Wang, Y., Lu, C., & Li, Z. (2024) · Virulence · doi:10.1080/21505594.2024.2427234 · Cited by 45

Apoptotic Cell Clearance in Development

Shklover, J., Levy‐Adam, F., & Kurant, E. (2015) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2015.07.024 · Cited by 45

Update on macrophages and innate immunity in scleroderma

Chia, D. J., & Lu, T. T. (2015) · Current Opinion in Rheumatology · doi:10.1097/bor.0000000000000218 · Cited by 43

Macrophage/monocyte-specific deletion of Ras homolog gene family member A (RhoA) downregulates fractalkine receptor and inhibits chronic rejection of mouse cardiac allografts

Liu, Y., Chen, W., Wu, C., Minze, L. J., Kubiak, J. Z., Li, X. C., Kloc, M., & Ghobrial, R. M. (2016) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2016.08.011 · Cited by 43

The role of PTEN in regulation of hepatic macrophages activation and function in progression and reversal of liver fibrosis

Cheng, Y., Tian, Y., Xia, J., Wu, X., Yang, Y., Li, X., Huang, C., Meng, X., Ma, T., & Li, J. (2017) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2017.01.005 · Cited by 43

Pandemic 2009 H1N1 Influenza Venus reporter virus reveals broad diversity of MHC class II-positive antigen-bearing cells following infection in vivo

DiPiazza, A. T., Nogales, A., Poulton, N. C., Wilson, P. C., Martínez‐Sobrido, L., & Sant, A. J. (2017) · Scientific Reports · doi:10.1038/s41598-017-11313-x · Cited by 43

The multifaceted role of the renal mononuclear phagocyte system

Viehmann, S. F., Böhner, A. M. C., Kurts, C., & Brähler, S. (2018) · Cellular Immunology · doi:10.1016/j.cellimm.2018.04.009 · Cited by 43

Nanomedicine enables spatiotemporally regulating macrophage-based cancer immunotherapy

Zhao, Y., Mamuti, M., An, H., Fang, X., Zhao, Y., & Wang, H. (2020) · Biomaterials · doi:10.1016/j.biomaterials.2020.120552 · Cited by 44

The emerging roles of m6A modification in liver carcinogenesis

Pan, X., Huang, C., & Li, J. (2020) · International Journal of Biological Sciences · doi:10.7150/ijbs.50003 · Cited by 43

Mast Cells Trigger Disturbed Bone Healing in Osteoporotic Mice

Fischer, V., Ragipoglu, D., Diedrich, J., Steppe, L., Dudeck, A., Schütze, K., Kalbitz, M., Gebhard, F., Haffner-Luntzer, M., & Ignatius, A. (2020) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.4455 · Cited by 42

Cell division in tissues enables macrophage infiltration

Akhmanova, M., Emtenani, S., Krueger, D., Gyoergy, A., Guarda, M., Vlasov, M., Vlasov, F., Akopian, A., Ratheesh, A., Renzis, S. D., et al. (2022) · Science · doi:10.1126/science.abj0425 · Cited by 42

Conceptual Approaches to Lung Injury and Repair

Zemans, R. L., Henson, P. M., Henson, J. E., & Janssen, W. J. (2015) · Annals of the American Thoracic Society · doi:10.1513/annalsats.201408-402mg · Cited by 42

Novel functions of macrophages in the heart: insights into electrical conduction, stress, and diastolic dysfunction

Leuschner, F., & Nahrendorf, M. (2019) · European Heart Journal · doi:10.1093/eurheartj/ehz159 · Cited by 43

Novel insights into the electrophysiology of murine cardiac macrophages: relevance of voltage-gated potassium channels

Simón-Chica, A., Fernández, M. C., Wülfers, E. M., Lother, A., Hilgendorf, I., Seemann, G., Ravens, U., Kohl, P. K., & Schneider‐Warme, F. (2021) · Cardiovascular Research · doi:10.1093/cvr/cvab126 · Cited by 43

The Macrophage Iron Signature in Health and Disease

Mertens, C., Marques, O., Horvat, N. K., Simonetti, M., Muckenthaler, M. U., & Jung, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22168457 · Cited by 44

Splenic Ly6Chi monocytes contribute to adverse late post-ischemic left ventricular remodeling in heme oxygenase-1 deficient mice

Tomczyk, M., Kraszewska, I., Szade, K., Bukowska-Straková, K., Meloni, M., Józkowicz, A., Dulak, J., & Jaźwa, A. (2017) · Basic Research in Cardiology · doi:10.1007/s00395-017-0629-y · Cited by 41

Triglyceride-Rich Lipoproteins Modulate the Distribution and Extravasation of Ly6C/Gr1low Monocytes

Saja, M. F., Baudino, L., Jackson, W. D., Cook, H. T., Malik, T. H., Fossati‐Jimack, L., Ruseva, M. M., Pickering, M. C., Woollard, K. J., & Botto, M. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.08.020 · Cited by 41

Interleukin-33 from Monocytes Recruited to the Lung Contributes to House Dust Mite-Induced Airway Inflammation in a Mouse Model

Tashiro, H., Takahashi, K., Hayashi, S., Kato, G., Kurata, K., Kimura, S. H., & Sueoka‐Aragane, N. (2016) · PLoS ONE · doi:10.1371/journal.pone.0157571 · Cited by 41

Role of Monocyte/Macrophages during HIV/SIV Infection in Adult and Pediatric Acquired Immune Deficiency Syndrome

Merino, K. M., Allers, C., Didier, E. S., & Kuroda, M. J. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01693 · Cited by 41

Stearic Acid Induces CD11c Expression in Proinflammatory Macrophages via Epidermal Fatty Acid Binding Protein

Zeng, J., Zhang, Y., Hao, J., Sun, Y., Liu, S., Bernlohr, D., Sauter, E. R., Cleary, M. P., Suttles, J., & Li, B. (2018) · The Journal of Immunology · doi:10.4049/jimmunol.1701416 · Cited by 41

Macrophages Switch Their Phenotype by Regulating Maf Expression during Different Phases of Inflammation

Kikuchi, K., Iida, M., Ikeda, N., Moriyama, S., Hamada, M., Takahashi, S., Kitamura, H., Watanabe, T., Hasegawa, Y., Hase, K., et al. (2018) · The Journal of Immunology · doi:10.4049/jimmunol.1800040 · Cited by 43

sEH Inhibitor Tppu Ameliorates Cecal Ligation and Puncture-Induced Sepsis by Regulating Macrophage Functions

Chen, Z., Tang, Y., Yu, J., Dong, R., Yang, Y., Fu, M., Luo, J., Hu, S., Wang, D. W., Tu, L., et al. (2019) · Shock · doi:10.1097/shk.0000000000001408 · Cited by 41

Remimazolam Protects Against LPS-Induced Endotoxicity Improving Survival of Endotoxemia Mice

Liu, X., Lin, S., Zhong, Y., Shen, J., Zhang, X., Luo, S., Li, H., Zhang, L., Zhou, S.-N., & Tang, J. Y. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.739603 · Cited by 41

Transplantation-Induced Ischemia-Reperfusion Injury Modulates Antigen Presentation by Donor Renal CD11c+F4/80+ Macrophages through IL-1R8 Regulation

Aiello, S., Podestà, M. A., Ordonez, P. Y. R., Pezzuto, F., Azzollini, N., Solini, S., Carrara, C., Todeschini, M., Casiraghi, F., Noris, M., et al. (2020) · Journal of the American Society of Nephrology · doi:10.1681/asn.2019080778 · Cited by 40

Targeting macrophage polarization by Nrf2 agonists for treating various xenobiotics-induced toxic responses

Wang, Y., Zhang, X., Meng, F.-G., & Zeng, T. (2021) · Toxicology Mechanisms and Methods · doi:10.1080/15376516.2021.1894624 · Cited by 40

Different Roles of Resident and Non-resident Macrophages in Cardiac Fibrosis

Hu, S., Yang, M., Huang, S., Zhong, S.-J., Zhang, Q., Ding, H., Xiong, X., Hu, S., & Yang, Y. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.818188 · Cited by 41

Composition and effects of seminal plasma in the female reproductive tracts on implantation of human embryos

Ahmadi, H., Csabai, T. J., Görgey, É., Rashidiani, S., Parhizkar, F., & Maleki, L. A. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113065 · Cited by 43

Inflammatory microenvironment in gastric premalignant lesions: implication and application

Zhang, S., Shen, Y., Liu, H., Zhu, D., Fang, J., Pan, H., & Liu, W. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1297101 · Cited by 45

Inflammation and mechanical force‐induced bone remodeling

Jeon, H. H., Huang, X., Rojas, L., Sripinun, P., Lee, J., Hong, J. J., & Graves, D. T. (2024) · Periodontology 2000 · doi:10.1111/prd.12619 · Cited by 45

Mucosal Macrophages Govern Intestinal Regeneration in Response to Injury

Moraitis, I., Taelman, J., Arozamena, B., Mularoni, L., Wienskowska, O., Garriga, X. S., Arregui, L., Stefanović, M., Farré, I. M., Guedea, F., et al. (2025) · Gastroenterology · doi:10.1053/j.gastro.2025.01.252 · Cited by 47

Regulation of ozone-induced lung inflammation and injury by the β-galactoside-binding lectin galectin-3

Sunil, V. R., Francis, M., Vayas, K. N., Cervelli, J. A., Choi, H., Laskin, J. D., & Laskin, D. L. (2015) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2015.02.002 · Cited by 40

Regulatory Macrophages and Tolerogenic Dendritic Cells in Myeloid Regulatory Cell-Based Therapies

Suuring, M., & Moreau, A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22157970 · Cited by 44

Unified nexus of macrophages and maresins in cardiac reparative mechanisms

Jadapalli, J. K., & Halade, G. V. (2018) · The FASEB Journal · doi:10.1096/fj.201800254r · Cited by 39

Monocytes and Macrophages in Spondyloarthritis: Functional Roles and Effects of Current Therapies

Martínez-Ramos, S., Rafael‐Vidal, C., Pego‐Reigosa, J. M., & García, S. (2022) · Cells · doi:10.3390/cells11030515 · Cited by 44

Tumor-associated macrophages in lymphoma: From mechanisms to therapy

Xiong, X., Xie, X., Wang, Z., Zhang, Y., & Wang, L. (2022) · International Immunopharmacology · doi:10.1016/j.intimp.2022.109235 · Cited by 40

Immunoregulatory role of platelet derivatives in the macrophage-mediated immune response

Anitua, E., Troya, M., & Alkhraisat, M. H. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1399130 · Cited by 40

Peripheral tissue chemokines: homeostatic control of immune surveillance T cells.

McCully, M. L., Kouzeli, A., & Moser, B. (2018) · Trends in Immunology · doi:10.1016/j.it.2018.06.003 · Cited by 37

Specialized Pro-resolving Lipid Mediators: Modulation of Diabetes-Associated Cardio-, Reno-, and Retino-Vascular Complications

de Gaetano, M., McEvoy, C. M., Andrews, D. C., Cacace, A., Hunter, J., Brennan, E. P., & Godson, C. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.01488 · Cited by 38

Desynchronization of the molecular clock contributes to the heterogeneity of the inflammatory response

Allen, N. C., Philip, N. H., Hui, L., Zhou, X., Franklin, R. A., Kong, Y., & Medzhitov, R. M. (2019) · Science Signaling · doi:10.1126/scisignal.aau1851 · Cited by 38

Cytochrome c oxidase dysfunction enhances phagocytic function and osteoclast formation in macrophages

Angireddy, R., Kazmi, H. R., Srinivasan, S., Sun, L., Iqbal, J. Z., Fuchs, S. Y., Guha, M., Kijima, T., Yuen, T., Zaidi, M., et al. (2019) · The FASEB Journal · doi:10.1096/fj.201900010rr · Cited by 39

Combination of novel and public RNA-seq datasets to generate an mRNA expression atlas for the domestic chicken

Bush, S. J., Freem, L. J., MacCallum, A. J., O’Dell, J., Wu, C., Afrasiabi, C., Psifidi, A., Stevens, M. P., Smith, J., SUMMERS, K. M., et al. (2018) · BMC Genomics · doi:10.1186/s12864-018-4972-7 · Cited by 40

An Hb-mediated circulating macrophage contributing to pulmonary vascular remodeling in sickle cell disease

Redinus, K., Baek, J. H., Yalamanoglu, A., Shin, H. K., Moldova, R., Harral, J. W., Swindle, D. C., Pak, D. I., Ferguson, S. K., Nuss, R., et al. (2019) · JCI Insight · doi:10.1172/jci.insight.127860 · Cited by 39

Biomarkers and Associated Immune Mechanisms for Early Detection and Therapeutic Management of Sepsis

Trzeciak, A. J., Pietropaoli, A. P., & Kim, M. (2020) · Immune Network · doi:10.4110/in.2020.20.e23 · Cited by 40

Macrophage Function and the Role of GSK3

Patel, S., & Werstuck, G. H. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22042206 · Cited by 39

Dissonant response of M0/M2 and M1 bone-marrow-derived macrophages to RhoA pathway interference

Liu, Y., Chen, W., Minze, L. J., Kubiak, J. Z., Li, X. C., Ghobrial, R. M., & Kloc, M. (2016) · Cell and Tissue Research · doi:10.1007/s00441-016-2491-x · Cited by 39

Role of Macrophage in Type 2 Diabetes Mellitus: Macrophage Polarization a New Paradigm for Treatment of Type 2 Diabetes Mellitus

Sur, D., & Banu, S. (2022) · Endocrine Metabolic & Immune Disorders - Drug Targets · doi:10.2174/1871530322666220630093359 · Cited by 38

Alveolar macrophages and airway hyperresponsiveness associated with respiratory syncytial virus infection

Wang, Y., Zheng, J., Wang, X., Yang, P., & Zhao, D. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1012048 · Cited by 38

Resident macrophages of the lung and liver: The guardians of our tissues

Kulle, A., Thanabalasuriar, A., Cohen, T. S., & Szydlowska, M. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1029085 · Cited by 43

Chronic exposure to polystyrene microplastics induces renal fibrosis via ferroptosis

Hong, R., Shi, Y., Fan, Z., Gao, Y., Chen, H., & Pan, C. (2024) · Toxicology · doi:10.1016/j.tox.2024.153996 · Cited by 43

The role of macrophage polarization in ulcerative colitis and its treatment

Qu, F., Xu, B.-Q., Kang, H., Wang, H., Ji, J., Pang, L., Wu, Y., & Zhou, Z. (2024) · Microbial Pathogenesis · doi:10.1016/j.micpath.2024.107227 · Cited by 42

M2-specific reduction of CD1d switches NKT cell-mediated immune responses and triggers metaflammation in adipose tissue

Zhang, H., Xue, R., Zhu, S., Fu, S., Chen, Z., Zhou, R., Zhigang, T., & Bai, L. (2017) · Cellular and Molecular Immunology · doi:10.1038/cmi.2017.11 · Cited by 38

The phosphatase PPM1A controls monocyte-to-macrophage differentiation

Smith, S. R., Schaaf, K., Rajabalee, N., Wagner, F., Duverger, A. E., Kutsch, O., & Sun, J. (2018) · Scientific Reports · doi:10.1038/s41598-017-18832-7 · Cited by 37

Twenty Novel Disease Group-Specific and 12 New Shared Macrophage Pathways in Eight Groups of 34 Diseases Including 24 Inflammatory Organ Diseases and 10 Types of Tumors

Lai, B., Wang, J., Fagenson, A. M., Sun, Y., Saredy, J., Lu, Y., Nanayakkara, G., Yang, W. Y., Yu, D., Shao, Y., et al. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02612 · Cited by 37

Macrophages in Skeletal Muscle Dystrophies, An Entangled Partner

Théret, M., Saclier, M., Messina, G., & Rossi, F. M. V. (2021) · Journal of Neuromuscular Diseases · doi:10.3233/jnd-210737 · Cited by 41

Developing a Novel Indium(III) Agent Based on Liposomes to Overcome Cisplatin-Induced Resistance in Breast Cancer by Multitargeting the Tumor Microenvironment Components

Jiang, M., Chu, Y., Yang, T., Li, W., Zhang, Z., Sun, H., Liang, H., & Yang, F. (2021) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.1c01068 · Cited by 38

Local action of cytokines and immune cells in communication between the conceptus and uterus during the critical period of early embryo development, attachment and implantation – Implications for embryo survival in cattle: A review

Campanile, G., Baruselli, P. S., Limone, A., & D’Occhio, M. J. (2021) · Theriogenology · doi:10.1016/j.theriogenology.2021.02.020 · Cited by 39

Immunosuppressive Cell Subsets and Factors in Myeloid Leukemias

Swatler, J., Turos-Korgul, L., Kozłowska, E., & Piwocka, K. (2021) · Cancers · doi:10.3390/cancers13061203 · Cited by 38

Coenzyme Q10 mitigates macrophage mediated inflammation in heart following myocardial infarction via the NLRP3/IL1β pathway

Pan, W., Zhou, G., Hu, M., Li, G., Zhang, M., Yang, H., Li, K., Li, J., Liu, T., Wang, Y., et al. (2024) · BMC Cardiovascular Disorders · doi:10.1186/s12872-024-03729-x · Cited by 38

Cytomegalovirus immune evasion of myeloid lineage cells

Brinkmann, M. M., Dağ, F., Hengel, H., Messerle, M., Kalinke, U., & Čičin‐Šain, L. (2015) · Medical Microbiology and Immunology · doi:10.1007/s00430-015-0403-4 · Cited by 38

Mitogen-Activated Protein Kinases and Mitogen Kinase Phosphatase 1: A Critical Interplay in Macrophage Biology

Lloberas, J., Estrella, L. V., Tur, J., Vico, T., & Celada, A. (2016) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2016.00028 · Cited by 37

The G1/S Specific Cyclin D2 Is a Regulator of HIV-1 Restriction in Non-proliferating Cells

Badía, R., Pujantell, M., Riveira‐Muñoz, E., Puig, T., Torres‐Torronteras, J., Martí, R., Clotet, B., Ampudia, R. M., Vives‐Pi, M., Esté, J. A., et al. (2016) · PLoS Pathogens · doi:10.1371/journal.ppat.1005829 · Cited by 37

Genetic Lineage Tracing of Pericardial Cavity Macrophages in the Injured Heart

Jin, H., Liu, K., Huang, X., Huo, H., Mou, J., Qiao, Z., He, B., & Zhou, B. (2022) · Circulation Research · doi:10.1161/circresaha.122.320567 · Cited by 38

Aggregated carbon dots‐loaded macrophages treat sepsis by eliminating multidrug‐resistant bacteria and attenuating inflammation

Li, L., Chen, L., Lu, Y., Li, B., Hu, R., Huang, L., Zhang, T., Wei, X., Yang, Z., & Mao, C. (2022) · Aggregate · doi:10.1002/agt2.200 · Cited by 39

Role of Macrophages in Air Pollution Exposure Related Asthma

Li, C.-H., Tsai, M.-L., Chiou, H.-Y. (., Lin, Y.-C., Liao, W., & Hung, C. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232012337 · Cited by 42

Effects of Cannabidiol on Innate Immunity: Experimental Evidence and Clinical Relevance

Martini, S., Gemma, A., Ferrari, M., Cosentino, M., & Marino, F. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24043125 · Cited by 39

Roles of differently polarized macrophages in the initiation and progressionof pancreatic cancer

Störz, P. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1237711 · Cited by 36

Antigen presenting cells in cancer immunity and mediation of immune checkpoint blockade

Wang, C., Chen, L., Fu, D., Liu, W., Puri, A., Kellis, M., & Yang, J. (2024) · Clinical & Experimental Metastasis · doi:10.1007/s10585-023-10257-z · Cited by 37

Alveolar Macrophages Are a Prominent but Nonessential Target for Murine Cytomegalovirus Infecting the Lungs

Farrell, H. E., Lawler, C., Oliveira, M. T., Davis-Poynter, N. J., & Stevenson, P. G. (2015) · Journal of Virology · doi:10.1128/jvi.02856-15 · Cited by 36

Targeting tumor tolerance: A new hope for pancreatic cancer therapy?

Delitto, D., Wallet, S. M., & Hughes, S. J. (2016) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2016.06.008 · Cited by 37

Immunomodulatory Effects and Induction of Apoptosis by Different Molecular Weight Chitosan Oligosaccharides in Head Kidney Macrophages From Blunt Snout Bream (Megalobrama amblycephala)

Wu, C., Dai, Y., Yuan, G., Su, J., & Liu, X. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.00869 · Cited by 35

HDAC8 inhibitor attenuates airway responses to antigen stimulus through synchronously suppressing galectin-3 expression and reducing macrophage-2 polarization

Li, M.-L., Su, X., Ren, Y., Zhao, X., Kong, L.-F., & Kang, J. (2020) · Respiratory Research · doi:10.1186/s12931-020-1322-5 · Cited by 36

The Role of Microglia during West Nile Virus Infection of the Central Nervous System

Stonedahl, S., Clarke, P., & Tyler, K. L. (2020) · Vaccines · doi:10.3390/vaccines8030485 · Cited by 37

The meningeal lymphatic system: a route for HIV brain migration?

Lamers, S. L., Rose, R., Ndhlovu, L. C., Nolan, D. J., Salemi, M., Maidji, E., Stoddart, C. A., & McGrath, M. S. (2015) · Journal of NeuroVirology · doi:10.1007/s13365-015-0399-y · Cited by 37

CCR2 imaging in human ST-segment elevation myocardial infarction

Lavine, K. J., Sultan, D. H., Luehmann, H. P., Detering, L., Zhang, X., Heo, G. S., Zhang, X., Hoelscher, M., Harrison, K., Combadière, C., et al. (2023) · Nature Cardiovascular Research · doi:10.1038/s44161-023-00335-6 · Cited by 35

Targeting Interactions between Fibroblasts and Macrophages to Treat Cardiac Fibrosis

Yang, B., Qiao, Y., Dong, Y., & Meng, Q. (2024) · Cells · doi:10.3390/cells13090764 · Cited by 39

Heat-killed Mycobacterium tuberculosis prime-boost vaccination induces myeloid-derived suppressor cells with spleen dendritic cell–killing capability

Ribechini, E., Eckert, I., Beilhack, A., du Plessis, N., Walzl, G., Schleicher, U., Ritter, U., & Lutz, M. B. (2019) · JCI Insight · doi:10.1172/jci.insight.128664 · Cited by 35

CSF-1R inhibition attenuates ischemia-induced renal injury and fibrosis by reducing Ly6C+ M2-like macrophage infiltration

Deng, X., Yang, Q., Wang, Y., Zhou, C., Guo, Y., Hu, Z., Liao, W., Xu, G., & Zeng, R. (2020) · International Immunopharmacology · doi:10.1016/j.intimp.2020.106854 · Cited by 37

Inorganic material based macrophage regulation for cancer therapy: basic concepts and recent advances

Zhao, R., Cao, J., Yang, X., Zhang, Q., Iqbal, M. Z., Lü, J., & Kong, X. (2021) · Biomaterials Science · doi:10.1039/d1bm00508a · Cited by 35

The Prognostic Potential of Human Prostate Cancer-Associated Macrophage Subtypes as Revealed by Single-Cell Transcriptomics

Siefert, J. C., Cioni, B., Muraro, M. J., Alshalalfa, M., Vivié, J., van der Poel, H. G., Schoots, I. G., Bekers, E. M., Feng, F. Y.-C., Wessels, L. F. A., et al. (2021) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-20-0740 · Cited by 34

IFN-γ-dependent epigenetic regulation instructs colitogenic monocyte/macrophage lineage differentiation in vivo

Nakanishi, Y., Sato, T., Takahashi, K., & Ohteki, T. (2018) · Mucosal Immunology · doi:10.1038/mi.2017.104 · Cited by 35

Naringin alleviates pneumonia caused by Klebsiella pneumoniae infection by suppressing NLRP3 inflammasome

Jing, X., Zhao, G., Wang, G., Huang, Q., Zou, W.-S., Huang, L., Li, W., Qiu, Z., & Xin, R. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.116028 · Cited by 34

CD16+ monocytes give rise to CD103+RALDH2+TCF4+ dendritic cells with unique transcriptional and immunological features

Wacleche, V. S., Cattin, A., Goulet, J.-P., Gauchat, D., Gosselin, A., Cleret‐Buhot, A., Zhang, Y., Tremblay, C. L., Routy, J., & Ancuța, P. (2018) · Blood Advances · doi:10.1182/bloodadvances.2018020123 · Cited by 32

Cholinergic modulation of the immune system – A novel therapeutic target for myocardial inflammation

Lu, J., & Wu, W. (2021) · International Immunopharmacology · doi:10.1016/j.intimp.2021.107391 · Cited by 36

Macrophages

Mallat, Z. (2014) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.114.304794 · Cited by 34

Stress hormone signaling through β‐adrenergic receptors regulates macrophage mechanotype and function

Kim, T.-H., Ly, C., Christodoulides, A., Nowell, C. J., Gunning, P. W., Sloan, E. K., & Rowat, A. A. C. (2018) · The FASEB Journal · doi:10.1096/fj.201801429rr · Cited by 34

3D micro-environment regulates NF-κβ dependent adhesion to induce monocyte differentiation

Bhattacharya, A., Agarwal, M., Mukherjee, R., Sen, P., & Sinha, D. K. (2018) · Cell Death and Disease · doi:10.1038/s41419-018-0993-z · Cited by 35

Development and Functional Differentiation of Tissue-Resident Versus Monocyte-Derived Macrophages in Inflammatory Reactions

Italiani, P., & Boraschi, D. (2017) · Results and problems in cell differentiation · doi:10.1007/978-3-319-54090-0_2 · Cited by 53

The origins and homeostasis of monocytes and tissue‐resident macrophages in physiological situation

Zhao, Y., Zou, W., Du, J., & Zhao, Y. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.26461 · Cited by 190

Origins and diversity of macrophages in health and disease

Sreejit, G., Fleetwood, A., Murphy, A. J., & Nagareddy, P. R. (2020) · La Trobe University · doi:10.26181/13661408

Monocytes and macrophages: developmental pathways and tissue homeostasis

Ginhoux, F., & Jung, S. (2014) · Nature Reviews Immunology · doi:10.1038/nri3671 · Cited by 1,840

Origin, development, and homeostasis of tissue‐resident macrophages

Haldar, M., & MURPHY, K. M. M. (2014) · Immunological Reviews · doi:10.1111/imr.12215 · Cited by 125