Origin and Functions of Tissue Macrophages

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

Polazzi, E., Mengoni, I., Caprini, M., Peña‐Altamira, E., Kurtys, E., & Monti, B. (2012) · Neurosignals · doi:10.1159/000337115 · Cited by 9,023

Macrophage activation and polarization: nomenclature and experimental guidelines

Murray, P. J., Allen, J. E., Biswas, S. K., Fisher, E. A., Gilroy, D. W., Goerdt, S., Gordon, S., Hamilton, J. A., Ivashkiv, L. B., Lawrence, T., et al. (2014) · Immunity · doi:10.1016/j.immuni.2014.06.008 · Cited by 6,337

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

Ginhoux, F., Greter, M., Leboeuf, M., Nandi, S., See, P., Gokhan, S., Mehler, M. F., Conway, S. J., Ng, L. G., Stanley, E. R., et al. (2010) · Science · doi:10.1126/science.1194637 · Cited by 5,175

Macrophage biology in development, homeostasis and disease

Wynn, T. A., Chawla, A., & Pollard, J. W. (2013) · Nature · doi:10.1038/nature12034 · Cited by 4,684 · cited 1×

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

Paolicelli, R. C., Bolasco, G., Pagani, F., Maggi, L., Scianni, M., Panzanelli, P., Giustetto, M., Ferreira, T. A., Guiducci, E., Dumas, L., et al. (2011) · Science · doi:10.1126/science.1202529 · Cited by 4,244

The Classical Complement Cascade Mediates CNS Synapse Elimination

Stevens, B., Allen, N. J., Vazquez, L. E., Howell, G. R., Christopherson, K. S., Nouri, N., Micheva, K. D., Mehalow, A. K., Huberman, A. D., Stafford, B., et al. (2007) · Cell · doi:10.1016/j.cell.2007.10.036 · Cited by 3,313

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

Yona, S., Kim, K.-W., Wolf, Y., Mildner, A., Varol, D., Breker, M., Strauss-Ayali, D., Viukov, S., Guilliams, M., Misharin, A., et al. (2013) · Immunity · doi:10.1016/j.immuni.2012.12.001 · Cited by 3,245

TREM2 Variants in Alzheimer's Disease

Guerreiro, R., Wojtas, A., Bras, J., Carrasquillo, M., Rogaeva, E., Majounie, E., Cruchaga, C., Sassi, C., Kauwe, J. S. K., Younkin, S., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1211851 · Cited by 3,020

Analysis of Fractalkine Receptor CX3CR1 Function by Targeted Deletion and Green Fluorescent Protein Reporter Gene Insertion

Jung, S., Aliberti, J., Graemmel, P., Sunshine, M. J., Kreutzberg, G. W., Sher, A., & Littman, D. R. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.11.4106-4114.2000 · Cited by 2,632

Microglia promote learning-dependent synapse formation through brain-derived neurotrophic factor

Parkhurst, C. N., Yang, G., Ninan, I., Savas, J. N., Yates, J. R., Lafaille, J. J., Hempstead, B. L., Littman, D. R., & Gan, W.-B. (2013) · Cell · doi:10.1016/j.cell.2013.11.030 · Cited by 2,599

Can the Inflammatory Response Be Evaluated Using 18F-FDG Within Zones of Microvascular Obstruction After Myocardial Infarction?

Prato, F. S., Butler, J., Sykes, J., Keenliside, L. D., Blackwood, K. J., Thompson, R. T., White, J. A., Mikami, Y., Thiessen, J. D., & Wisenberg, G. (2015) · Journal of Nuclear Medicine · doi:10.2967/jnumed.114.147835 · Cited by 25

Cytomegalovirus host entry and spread

Farrell, H. E., & Stevenson, P. G. (2019) · Journal of General Virology · doi:10.1099/jgv.0.001230 · Cited by 25

Emerging Evidence of Macrophage Contribution to Hyperinnervation and Nociceptor Sensitization in Vulvodynia

Barry, C., Matusica, D., & Haberberger, R. V. (2019) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2019.00186 · Cited by 25

Role of Innate Immune System in Environmental Lung Diseases

Guttenberg, M. A., Vose, A. T., & Tighe, R. M. (2021) · Current Allergy and Asthma Reports · doi:10.1007/s11882-021-01011-0 · Cited by 27

The importance of N6-methyladenosine modification in tumor immunity and immunotherapy

Zhang, Z., Liu, F., Chen, W., Liao, Z., Zhang, B., Zhang, B., Chu, L., Chu, L., & Zhang, Z. (2022) · Experimental Hematology and Oncology · doi:10.1186/s40164-022-00281-2 · Cited by 26

Alveolar macrophage metabolic programming via a C-type lectin receptor protects against lipo-toxicity and cell death

Scur, M., Mahmoud, A. B., Dey, S., Abdalbarri, F., Stylianides, I., Medina-Luna, D., Gamage, G. S., Woblistin, A., Wilson, A., Zein, H. S., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-34935-w · Cited by 27

Lysosome blockade induces divergent metabolic programs in macrophages and tumours for cancer immunotherapy

Ma, J., Ma, R., Zeng, X., Zhang, L., Liu, J., Zhang, W., Li, T., Niu, H., Bao, G., Wang, C., et al. (2023) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-023-02768-0 · Cited by 24

Role of innate immune cells in multiple sclerosis

Prado, C. E., Herrada, A. A., Hevia, D., Galleguillos, L., & Escobedo, N. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1540263 · Cited by 26

Macrophage polarization in diabetic vascular complications: mechanistic insights and therapeutic targets

Cao, L., Ding, L., Xia, Q., Zhang, Z., Li, M., Song, S., Yin, K., Li, Z., Li, X., Wang, Z., et al. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-025-07075-0 · Cited by 30

IFN-γ in tissue-immune homeostasis and antitumor immunity

Kwon, B. (2017) · Cellular and Molecular Immunology · doi:10.1038/cmi.2017.95 · Cited by 24

Cell‐specific immune‐modulation of cadmium on murine macrophages and mast cell lines in vitro

García‐Mendoza, D., Han, B., van den Berg, H. H. J., & van den Brink, N. W. (2019) · Journal of Applied Toxicology · doi:10.1002/jat.3788 · Cited by 24

Negative feedback loop of ERK/CREB/miR‐212‐3p inhibits HBeAg‐induced macrophage activation

Chen, W., Bian, H., Xie, X., Yang, X., Bi, B., Li, C., Zhang, Y., Zhu, Q., Song, J., Qin, C., et al. (2020) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.15723 · Cited by 26

The Role of Macrophages During Mammalian Tissue Remodeling and Regeneration Under Infectious and Non-Infectious Conditions

Bohaud, C., Johansen, M. D., Jørgensen, C., Kremer, L., Ipseiz, N., & Djouad, F. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.707856 · Cited by 25

Macrophages in Atheromatous Plaque Developmental Stages

von Ehr, A., Bode, C., & Hilgendorf, I. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.865367 · Cited by 24

Epigenomic regulation of macrophage polarization: Where do the nuclear receptors belong?

Czimmerer, Z., & Nagy, L. (2023) · Immunological Reviews · doi:10.1111/imr.13209 · Cited by 24

Role of m6A methylation in retinal diseases

Zhu, X., Zhou, C., Zhao, S., & Zheng, Z. J. (2023) · Experimental Eye Research · doi:10.1016/j.exer.2023.109489 · Cited by 24

Hybrid PET/MR imaging in myocardial inflammation post-myocardial infarction

Wilk, B., Wisenberg, G., Dharmakumar, R., Thiessen, J. D., Goldhawk, D. E., & Prato, F. S. (2019) · Journal of Nuclear Cardiology · doi:10.1007/s12350-019-01973-9 · Cited by 28

Regenerative cross talk between cardiac cells and macrophages

Whitehead, A. J., & Engler, A. J. (2021) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00056.2021 · Cited by 24

Do Vascular Smooth Muscle Cells Differentiate to Macrophages in Atherosclerotic Lesions?

Świrski, F. K., & Nahrendorf, M. (2014) · Circulation Research · doi:10.1161/circresaha.114.304925 · Cited by 26

Biomimetic Systems Involving Macrophages and Their Potential for Targeted Drug Delivery

Savchenko, I. V., Zlotnikov, I. D., & Kudryashova, E. V. (2023) · Biomimetics · doi:10.3390/biomimetics8070543 · Cited by 25

Alveolar macrophages: guardians of the alveolar lipid galaxy

Little, I., Bersie, S. M., Redente, E. F., McCubbrey, A. L., & Tarling, E. J. (2025) · Current Opinion in Lipidology · doi:10.1097/mol.0000000000000987 · Cited by 23

Activated Macrophages of Monocytic Origin Predominantly Express Proinflammatory Cytokine Genes, Whereas Kupffer Cells Predominantly Express Anti-Inflammatory Cytokine Genes

Lokhonina, А. V., Elchaninov, A. V., Fatkhudinov, T., Макаров, А. В., Arutyunyan, I. V., Grinberg, M., Glinkina, V. V., Surovtsev, V. V., Bolshakova, G. B., Goldshtein, D. V., et al. (2019) · BioMed Research International · doi:10.1155/2019/3912142 · Cited by 23

Monocyte-derived dendritic cells in malaria

Hirako, I. C., de Assis, P. A., Galvão-Filho, B., Luster, A. D., Antonelli, L. R. D. V., & Gazzinelli, R. T. (2019) · Current Opinion in Microbiology · doi:10.1016/j.mib.2019.08.002 · Cited by 23

Endoderm-Derived Myeloid-like Metaphocytes in Zebrafish Gill Mediate Soluble Antigen-Induced Immunity

Lin, X., Zhou, Q., Lin, G., Zhao, C., & Wen, Z. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.108227 · Cited by 23

Macrophage phenotypes and monocyte subsets after destabilization of the medial meniscus in mice

Utomo, L., Fahy, N., Kops, N., van Tiel, S. T., Waarsing, J. H., Verhaar, J. A. N., Leenen, P. J. M., van Osch, G. J. V. M., & Bastiaansen-Jenniskens, Y. M. (2020) · Journal of Orthopaedic Research® · doi:10.1002/jor.24958 · Cited by 23

Insights from Transcriptomics: CD163+ Profibrotic Lung Macrophages in COVID-19

Bhattacharya, M. (2022) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2022-0107tr · Cited by 24

Spatial architecture of the cochlear immune microenvironment in noise-induced and age-related sensorineural hearing loss

Li, P., Qian, T., & Sun, S. (2022) · International Immunopharmacology · doi:10.1016/j.intimp.2022.109488 · Cited by 23

Transcriptomic Analysis of Macrophage Polarization Protocols: Vitamin D3 or IL-4 and IL-13 Do Not Polarize THP-1 Monocytes into Reliable M2 Macrophages

Rynikova, M., Adamkova, P., Hradická, P., Štofilová, J., Harvanová, D., Matejová, J., & Demečková, V. (2023) · Biomedicines · doi:10.3390/biomedicines11020608 · Cited by 22

Fate PPAR-titioning: PPAR-γ 'instructs' alveolar macrophage development

Ginhoux, F. (2014) · Nature Immunology · doi:10.1038/ni.3011 · Cited by 23

NMAAP1 Expressed in BCG-Activated Macrophage Promotes M1 Macrophage Polarization

Liu, Q., Tian, Y., Zhao, X., Jing, H., Xie, Q., Li, P., Li, D., Yan, D., & Zhu, X. (2015) · Molecules and Cells · doi:10.14348/molcells.2015.0125 · Cited by 23

The Topography of Silica Films Modulates Primary Macrophage Morphology and Function

Makaremi, S., Luu, H., Boyle, J. P., Zhu, Y., Cerson, C., Bowdish, D. M. E., & Moran-Mirabal, J. M. (2019) · Advanced Materials Interfaces · doi:10.1002/admi.201900677 · Cited by 23

A new biomarker candidate for spinal muscular atrophy: Identification of a peripheral blood cell population capable of monitoring the level of survival motor neuron protein

Otsuki, N., Arakawa, R., Kaneko, K., Aoki, R., Arakawa, M., & Saito, K. (2018) · PLoS ONE · doi:10.1371/journal.pone.0201764 · Cited by 23

Tumor-Infiltrating Immune Cells in Colorectal Cancer

Ferkel, S. A. M., Holman, E. A., Sojwal, R. S., Rubin, S. J. S., & Rogalla, S. (2024) · Neoplasia · doi:10.1016/j.neo.2024.101091 · Cited by 27

Macrophage Subpopulation Promotes Skeletal Muscle Regeneration Through HGF / MET Signaling‐Mediated Skeletal Muscle Stem Cell Proliferation

Koike, H., Sugimura, M., Ouchi, R., Yoshimoto, Y., Manabe, I., & Oishi, Y. (2025) · Aging Cell · doi:10.1111/acel.70042 · Cited by 22

Polysaccharide Nanoadjuvants Engineered via Phenotype-Specific Nanoprobe-Assisted Phenotypic Screen Reprogram Macrophage Cell Functions for Cancer and Rheumatoid Arthritis Therapy

Mo, X., Shen, A., Han, Y., Xu, L., Miao, J., Xu, D., Ji, Q., Cao, Y., Ge, G., Zhu, X., et al. (2025) · ACS Nano · doi:10.1021/acsnano.4c16671 · Cited by 23

Protein-Tyrosine Phosphatase-1B Mediates Sleep Fragmentation-Induced Insulin Resistance and Visceral Adipose Tissue Inflammation in Mice

Gozal, D., Khalyfa, A., Qiao, Z., Akbarpour, M., Maccari, R., & Ottanà, R. (2017) · SLEEP · doi:10.1093/sleep/zsx111 · Cited by 22

Lung macrophages: current understanding of their roles in Ozone-induced lung diseases

Patial, S., & Saini, Y. (2020) · Critical Reviews in Toxicology · doi:10.1080/10408444.2020.1762537 · Cited by 23

Macrophage Polarization in Chronic Lymphocytic Leukemia: Nurse-Like Cells Are the Caretakers of Leukemic Cells

Mesaros, O., Jimbu, L., Neaga, A., Popescu, C., Berceanu, I., Tomuleasa, C., Fetică, B., & Zdrenghea, M. (2020) · Biomedicines · doi:10.3390/biomedicines8110516 · Cited by 21

Renewal of embryonic and neonatal-derived cardiac-resident macrophages in response to environmental cues abrogated their potential to promote cardiomyocyte proliferation via Jagged-1–Notch1

Chen, R., Zhang, S., Liu, F., Xia, L., Wang, C., Shotorbani, S. S., Xu, H., Chakrabarti, S., Peng, T., & Su, Z. (2022) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2022.08.016 · Cited by 22

A Review of Signaling Transduction Mechanisms in Osteoclastogenesis Regulation by Autophagy, Inflammation, and Immunity

Tong, X., Yu, G., Fu, X., Song, R., Gu, J., & Liu, Z. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23179846 · Cited by 23

Nur77 and PPARγ regulate transcription and polarization in distinct subsets of M2-like reparative macrophages during regenerative inflammation

Garabuczi, É., Tarban, N., Fige, É., Patsalos, A., Halász, L., Szendi-Szatmári, T., Sarang, Z., Király, R., & Szondy, Z. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1139204 · Cited by 22

Schisandrin A ameliorates airway inflammation in model of asthma by attenuating Th2 response

Qiu, Q., Zhang, W., Liu, K., Huang, F., Su, J., Deng, L., He, J., Lin, Q., & Luo, L. (2023) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2023.175850 · Cited by 22

Microglia‐derived extracellular vesicles in homeostasis and demyelination/remyelination processes

Mancini, V. S. B. W., Mattera, V. S., Pasquini, J. M., Pasquini, L. A., & Correale, J. D. (2023) · Journal of Neurochemistry · doi:10.1111/jnc.16011 · Cited by 26

Macrophages in Invertebrates: From Insects and Crustaceans to Marine Bivalves

Abnave, P., Muracciole, X., & Ghigo, É. (2017) · Results and problems in cell differentiation · doi:10.1007/978-3-319-54090-0_6 · Cited by 22

Genetic Models of Macrophage Depletion

Hua, L., Shi, J., Shultz, L. D., & Ren, G. (2018) · Methods in molecular biology · doi:10.1007/978-1-4939-7837-3_22 · Cited by 25

Influence of Immunological Maturity on Respiratory Syncytial Virus-Induced Morbidity in Young Children

Verhoeven, D. E. (2018) · Viral Immunology · doi:10.1089/vim.2018.0121 · Cited by 23

Simple propagation method for resident macrophages by co-culture and subculture, and their isolation from various organs

Ogawa, K., Tsurutani, M., Hashimoto, A., & Soeda, M. (2019) · BMC Immunology · doi:10.1186/s12865-019-0314-z · Cited by 22

Diastolic dysfunction in a pre-clinical model of diabetes is associated with changes in the cardiac non-myocyte cellular composition

Cohen, C. D., Blasio, M. J. D., Lee, M. K. S., Farrugia, G. E., Prakoso, D., Krstevski, C., Deo, M., Donner, D. G., Kiriazis, H., Flynn, M., et al. (2021) · Cardiovascular Diabetology · doi:10.1186/s12933-021-01303-9 · Cited by 24

Inflammatory and non-inflammatory monocytes as novel prognostic biomarkers of survival in SOD1G93A mouse model of Amyotrophic Lateral Sclerosis

Gasco, S., Zaragoza, P., García‐Redondo, A., Calvo, A. C., & Osta, R. (2017) · PLoS ONE · doi:10.1371/journal.pone.0184626 · Cited by 22

Cancer systems immunology

Reticker-Flynn, N. E., & Engleman, E. G. (2020) · eLife · doi:10.7554/elife.53839 · Cited by 23

Inhibition of MyD88 by a novel inhibitor reverses two-thirds of the infarct area in myocardial ischemia and reperfusion injury.

Miao, Y., Ding, Z., Zou, Z., Yang, Y., Yang, M. H., Zhang, X., Li, Z., Zhou, L., Zhang, L., Zhang, X., et al. (2020) · PubMed Central · Cited by 21

How Have Leukocyte In Vitro Chemotaxis Assays Shaped Our Ideas about Macrophage Migration?

Rumianek, A. N., & Greaves, D. R. (2020) · Biology · doi:10.3390/biology9120439 · Cited by 21

Cardiac cell type-specific responses to injury and contributions to heart regeneration

Zhang, W., Liang, J., & Han, P. (2021) · Cell Regeneration · doi:10.1186/s13619-020-00065-1 · Cited by 23

Depletion of Microglia in an Ex Vivo Brain Slice Culture Model of West Nile Virus Infection Leads to Increased Viral Titers and Cell Death

Stonedahl, S., Leser, J. S., Clarke, P., & Tyler, K. L. (2022) · Microbiology Spectrum · doi:10.1128/spectrum.00685-22 · Cited by 22

Loss of Lipocalin 10 Exacerbates Diabetes-Induced Cardiomyopathy via Disruption of Nr4a1-Mediated Anti-Inflammatory Response in Macrophages

Li, Q., Li, Y., Huang, W. C., Wang, X., Liu, Z., Chen, J., Fan, Y., Peng, T., Sadayappan, S., Wang, Y., et al. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.930397 · Cited by 21

Myeloperoxidase as a Marker to Differentiate Mouse Monocyte/Macrophage Subsets

Gurski, C. J., & Dittel, B. N. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23158246 · Cited by 24

Phenotypic characteristics of peripheral immune cells of Myalgic encephalomyelitis/chronic fatigue syndrome via transmission electron microscopy: A pilot study

Jahanbani, F., Maynard, R. D., Sing, J., Jahanbani, S., Perrino, J. J., Spacek, D. V., Davis, R. W., & Snyder, M. P. (2022) · PLoS ONE · doi:10.1371/journal.pone.0272703 · Cited by 19

Myeloid‐specific blockade of Notch signaling alleviates murine pulmonary fibrosis through regulating monocyte‐derived Ly6c lo MHCII hi alveolar macrophages recruitment and TGF‐β secretion

Zhang, N., Yang, K., Bai, J., Yi, J., Gao, C.-C., Zhao, J., Liang, S.-Q., Wei, T., Feng, L., Song, L., et al. (2020) · The FASEB Journal · doi:10.1096/fj.201903086rr · Cited by 21

Roles of airway and intestinal epithelia in responding to pathogens and maintaining tissue homeostasis

Ambrogi, M., & Vezina, C. M. (2024) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2024.1346087 · Cited by 21

Characterization and treatment outcomes of malignant histiocytoses in a retrospective series of 141 cases in France

Bigenwald, C., Roos‐Weil, D., Pagès, A., Hélias‐Rodzewicz, Z., Copie‐Bergman, C., Nashvi, M., Khneisser, P., Parrens, M., Traverse‐Glehen, A., Ray-Coquard, I. L., et al. (2025) · Blood Advances · doi:10.1182/bloodadvances.2024015208 · Cited by 20

Identification of a Novel Antisepsis Pathway: Sectm1a Enhances Macrophage Phagocytosis of Bacteria through Activating GITR

Mu, X., Wang, P., Wang, X., Li, Y., Zhao, H., Li, Q., Essandoh, K., Deng, S., Peng, T., & Fan, G. (2020) · The Journal of Immunology · doi:10.4049/jimmunol.2000440 · Cited by 20

Modeled vascular microenvironments: immune-endothelial cell interactions in vitro

Silberman, J., Jha, A., Ryan, H., Abbate, T., & Moore, E. (2021) · Drug Delivery and Translational Research · doi:10.1007/s13346-021-00970-1 · Cited by 20

Different Induction of PD-L1 (CD274) and PD-1 (CD279) Expression in THP-1-Differentiated Types 1 and 2 Macrophages

Lai, C.-Y., Tseng, P., Chen, C., Satria, R. D., Wang, Y.-T., & Lin, C. (2021) · Journal of Inflammation Research · doi:10.2147/jir.s329921 · Cited by 21

Intercellular genetic tracing of cardiac endothelium in the developing heart

Liu, K., Jin, H., Zhang, S., Tang, M., Meng, X., Li, Y., Pu, W., Lui, K. O., & Zhou, B. (2023) · Developmental Cell · doi:10.1016/j.devcel.2023.05.021 · Cited by 20

Targeting Macrophages in Organ Transplantation: A Step Toward Personalized Medicine

Owen, M. C., & Kopecky, B. J. (2024) · Transplantation · doi:10.1097/tp.0000000000004978 · Cited by 21

Probiotics Differently Affect Gut-Associated Lymphoid Tissue Indolamine-2,3-Dioxygenase mRNA and Cerebrospinal Fluid Neopterin Levels in Antiretroviral-Treated HIV-1 Infected Patients: A Pilot Study

Scagnolari, C., Scheri, G. C., Selvaggi, C., Schietroma, I., Fard, S. N., Mastrángelo, A., Giustini, N., Serafino, S., Pinacchio, C., Pavone, P., et al. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17101639 · Cited by 21

Distinguishing Human Peripheral Blood NK Cells from CD56dimCD16dimCD69+CD103+ Resident Nasal Mucosal Lavage Fluid Cells

Rebuli, M. E., Pawlak, E. A., Walsh, D. M., Martin, E. M., & Jaspers, I. (2018) · Scientific Reports · doi:10.1038/s41598-018-21443-5 · Cited by 21

Human macrophages and innate lymphoid cells: Tissue-resident innate immunity in humanized mice

Alisjahbana, A., Mohammad, I., Gao, Y., Evren, E., Ringqvist, E. E., & Willinger, T. (2019) · Biochemical Pharmacology · doi:10.1016/j.bcp.2019.113672 · Cited by 22

Homogentisic acid-derived pigment as a biocompatible label for optoacoustic imaging of macrophages

Weidenfeld, I., Zakian, C. M., Duewell, P., Chmyrov, A., Klemm, U., Aguirre, J., Ntziachristos, V., & Stiel, A. C. (2019) · Nature Communications · doi:10.1038/s41467-019-13041-4 · Cited by 20

Metabolic reprogramming shapes post-translational modification in macrophages

Han, Z., Shen, Y., Yan, Y., Bin, P., Zhang, M., & Gan, Z. (2025) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2025.101338 · Cited by 19

Therapeutic Spp1 silencing in TREM2+ cardiac macrophages suppresses atrial fibrillation

Momin, N., Pabel, S., Rudra, A., Kumowski, N., Lee, I., Seung, H., Mentkowski, K. I., Bapat, A. C., Yamazoe, M., Stengel, L., et al. (2026) · Nature Cardiovascular Research · doi:10.1038/s44161-026-00806-6 · Cited by 23

New insights into macrophage subsets in atherosclerosis

Wang, Y., Wang, Q. A., & Xu, D. (2022) · Journal of Molecular Medicine · doi:10.1007/s00109-022-02224-0 · Cited by 19

Innate Immune Memory in Macrophages

Maheshwari, A. (2023) · Newborn · doi:10.5005/jp-journals-11002-0058 · Cited by 18

Induction of Skin Cancer by Long-Term Blue Light Irradiation

Hiramoto, K., Kubo, S., Tsuji, K., Sugiyama, D., & Hamano, H. (2023) · Biomedicines · doi:10.3390/biomedicines11082321 · Cited by 20

EGF-conditioned M1 macrophages Convey reduced inflammation into corneal endothelial cells through exosomes

Lee, S., Lee, S. H., Koh, A., & Kim, K. W. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e26800 · Cited by 19

Lung Macrophage Diversity and Asthma.

Lumeng, C. N.-K. (2016) · PubMed Central · doi:10.1513/annalsats.201506-384mg · Cited by 19

Cell Type Preference of a Novel Human Derived Cell-Permeable Peptide dNP2 and TAT in Murine Splenic Immune Cells

Lim, S., Lee, J.-A., Koo, J., Kang, T. G., Ha, S., & Choi, J. (2016) · PLoS ONE · doi:10.1371/journal.pone.0155689 · Cited by 19

Functional diversity of macrophages in vascular biology and disease

Park, I., Kassiteridi, C., & Monaco, C. G. (2017) · Vascular Pharmacology · doi:10.1016/j.vph.2017.10.005 · Cited by 19

New insights into the immunomodulatory role of exosomes in cardiovascular disease

Jiang, W., & Wang, M. (2019) · Reviews in Cardiovascular Medicine · doi:10.31083/j.rcm.2019.03.528 · Cited by 19

Extracellular Vesicles in Innate Immune Cell Programming

Akbar, N., Paget, D., & Choudhury, R. P. (2021) · Biomedicines · doi:10.3390/biomedicines9070713 · Cited by 20

Latitudinal and longitudinal regulation of tissue macrophages in inflammatory diseases

He, X.-Y., Tan, S., Shao, Z., & Wang, X. (2021) · Genes & Diseases · doi:10.1016/j.gendis.2021.06.007 · Cited by 20

Transitional premonocytes emerge in the periphery for host defense against bacterial infections

Teh, Y. C., Chooi, M. Y., Liu, D., Kwok, I., Lai, G. C., Yong, L. A. O., Ng, M. S. F., Li, J. L. Y., Tan, Y., Evrard, M., et al. (2022) · Science Advances · doi:10.1126/sciadv.abj4641 · Cited by 20

Transport of cargo from periphery to brain by circulating monocytes

Cintron, A. F., Dalal, N. V., Dooyema, J. M., Betarbet, R. S., & Walker, L. C. (2015) · Brain Research · doi:10.1016/j.brainres.2015.06.047 · Cited by 19

Identifying Novel Targets for Treatment of Liver Fibrosis: What Can We Learn from Injured Tissues which Heal Without a Scar?

Pritchard, M. T., & McCracken, J. M. (2015) · Current Drug Targets · doi:10.2174/1389450116666150825111439 · Cited by 19

In focus in HCB

Taatjes, D. J., & Roth, J. (2017) · Histochemistry and Cell Biology · doi:10.1007/s00418-017-1541-0 · Cited by 19

Lung Interstitial Macrophages: Establishing Identity and Uncovering Heterogeneity

Koch, C. M., Chiu, S. F., Misharin, A. V., & Ridge, K. M. (2017) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2017-0150ed · Cited by 19

Deconstructing Immune Microenvironments of Lymphoid Tissues for Reverse Engineering

Witzel, I., Nasser, R. A., Garcia‐Sabaté, A., Sapudom, J., Ma, C., Chen, W., & Teo, J. C. M. (2018) · Advanced Healthcare Materials · doi:10.1002/adhm.201801126 · Cited by 17

Liver Regeneration in Chronic Liver Injuries: Basic and Clinical Applications Focusing on Macrophages and Natural Killer Cells

Qian, Y., Shang, Z., Gao, Y., Wu, H., & Kong, X. (2022) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2022.05.014 · Cited by 18

Immunomodulatory responses of differentially polarized macrophages to fungal infections

Xie, Y., Zhou, X., Zhang, J., Yu, H. B., & Song, Z. (2022) · International Immunopharmacology · doi:10.1016/j.intimp.2022.109089 · Cited by 18

Macrophage, a potential targeted therapeutic immune cell for cardiomyopathy

Chen, G., Jiang, H., Yao, Y., Tao, Z., Chen, W., Huang, F., & Chen, X. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.908790 · Cited by 18

The tumor-immune ecosystem in shaping metastasis

Gao, Y., Rosen, J. M., & Zhang, X. H.-F. (2023) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00132.2022 · Cited by 18

Defining and targeting macrophage heterogeneity in the mammary gland and breast cancer

Elfstrum, A. K., Bapat, A. S., & Schwertfeger, K. L. (2024) · Cancer Medicine · doi:10.1002/cam4.7053 · Cited by 22

IL20Rb aggravates pulmonary fibrosis through enhancing bone marrow derived profibrotic macrophage activation

Zhu, J., Jiang, Q., Gao, S., Xia, Q., Zhang, H., Liu, B., Zhao, R., Jiang, H., Li, X., Xu, A., et al. (2024) · Pharmacological Research · doi:10.1016/j.phrs.2024.107178 · Cited by 18

Mechanisms underlying aryl hydrocarbon receptor-driven divergent macrophage function

Malany, K., Li, X., Vogel, C. F. A., & Ehrlich, A. K. (2024) · Toxicological Sciences · doi:10.1093/toxsci/kfae050 · Cited by 18

Contribution of IL-17C-mediated macrophage polarization to Type 17 inflammation in neutrophilic asthma

Wen, Y., Chen, Q. P., Wang, H., Xie, S., Chen, H., Yao, W., Zhang, L., Sun, W., Wen, J., Yang, X., et al. (2024) · Cell Communication and Signaling · doi:10.1186/s12964-024-01937-8 · Cited by 18

The Role of Phagocytes and NETs in Dermatophytosis

Yoshikawa, F. S. Y., & de Almeida, S. R. (2016) · Mycopathologia · doi:10.1007/s11046-016-0069-5 · Cited by 18

A Benzenediamine Analog FC-99 Drives M2 Macrophage Polarization and Alleviates Lipopolysaccharide- (LPS-) Induced Liver Injury

Gong, W., Zhu, H., Lü, L., Hou, Y., & Dou, H. (2019) · Mediators of Inflammation · doi:10.1155/2019/7823069 · Cited by 18

Signaling of Macrophages that Contours the Tumor Microenvironment for Promoting Cancer Development

Messex, J. K., Byrd, C. J., & Liou, G. (2020) · Cells · doi:10.3390/cells9040919 · Cited by 18

Rational combination of an immune checkpoint inhibitor with CSF1R inhibitor–loaded nanoparticle enhances anticancer efficacy

Ramesh, A., Malik, V., Karuppiah, H. A. R., Smith, H., & Kulkarni, A. A. (2021) · Drug Delivery and Translational Research · doi:10.1007/s13346-021-01040-2 · Cited by 18

Development and Functional Differentiation of Tissue-Resident Versus Monocyte-Derived Macrophages in Inflammatory Reactions

Italiani, P., & Boraschi, D. (2017) · Results and problems in cell differentiation · doi:10.1007/978-3-319-54090-0_2 · Cited by 53

The origins and homeostasis of monocytes and tissue‐resident macrophages in physiological situation

Zhao, Y., Zou, W., Du, J., & Zhao, Y. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.26461 · Cited by 190

Origins and diversity of macrophages in health and disease

Sreejit, G., Fleetwood, A., Murphy, A. J., & Nagareddy, P. R. (2020) · La Trobe University · doi:10.26181/13661408

Monocytes and macrophages: developmental pathways and tissue homeostasis

Ginhoux, F., & Jung, S. (2014) · Nature Reviews Immunology · doi:10.1038/nri3671 · Cited by 1,840

Origin, development, and homeostasis of tissue‐resident macrophages

Haldar, M., & MURPHY, K. M. M. (2014) · Immunological Reviews · doi:10.1111/imr.12215 · Cited by 125