The DOI matches its Crossref record; 178 of the 178 references it cites were found in a registry or an index.
Inflammation and Cancer: Triggers, Mechanisms, and Consequences
Open accessAbstract
Inflammation predisposes to the development of cancer and promotes all stages of tumorigenesis. Cancer cells, as well as surrounding stromal and inflammatory cells, engage in well-orchestrated reciprocal interactions to form an inflammatory tumor microenvironment (TME). Cells within the TME are highly plastic, continuously changing their phenotypic and functional characteristics. Here, we review the origins of inflammation in tumors, and the mechanisms whereby inflammation drives tumor initiation, growth, progression, and metastasis. We discuss how tumor-promoting inflammation closely resembles inflammatory processes typically found during development, immunity, maintenance of tissue homeostasis, or tissue repair and illuminate the distinctions between tissue-protective and pro-tumorigenic inflammation, including spatiotemporal considerations. Defining the cornerstone rules of engagement governing molecular and cellular mechanisms of tumor-promoting inflammation will be essential for further development of anti-cancer therapies.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The text we found for this paper looks like another document, so the self-check wasn’t run.
Citations
Cites
Hallmarks of Cancer: The Next Generation
Hanahan, D., & Weinberg, R. A. (2011) · Cell · doi:10.1016/j.cell.2011.02.013 · Cited by 66,590
PD-1 and PD-L1 Immune Checkpoint Blockade to Treat Breast Cancer
Hartkopf, A. D., Taran, F., Wallwiener, M., Walter, C. B., Krämer, B., Grischke, E., & Brucker, S. Y. (2016) · Breast Care · doi:10.1159/000453569 · Cited by 30,989
Mantovani, A., Allavena, P., Sica, A., & Balkwill, F. (2008) · Nature · doi:10.1038/nature07205 · Cited by 11,399
Immunity, Inflammation, and Cancer
Grivennikov, S. I., Greten, F. R., & Karin, M. (2010) · Cell · doi:10.1016/j.cell.2010.01.025 · Cited by 10,755
Self-citationGalluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., et al. (2018) · Cell Death & Differentiation · doi:10.1038/s41418-017-0012-4 · Cited by 6,680
Origin and physiological roles of inflammation
Medzhitov, R. (2008) · Nature · doi:10.1038/nature07201 · Cited by 6,618
Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion
Schreiber, R. D., Old, L. J., & Smyth, M. J. (2011) · Science · doi:10.1126/science.1203486 · Cited by 6,474
Understanding the tumor immune microenvironment (TIME) for effective therapy
Binnewies, M., Roberts, E. W., Kersten, K., Chan, V., Fearon, D. F., Merad, M., Coussens, L. M., Gabrilovich, D. I., Ostrand-Rosenberg, S., Hedrick, C. C., et al. (2018) · Nature Medicine · doi:10.1038/s41591-018-0014-x · Cited by 6,145
The future of immune checkpoint therapy
Sharma, P., & Allison, J. P. (2015) · Science · doi:10.1126/science.aaa8172 · Cited by 4,878
Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
Hanahan, D., & Coussens, L. M. (2012) · Cancer Cell · doi:10.1016/j.ccr.2012.02.022 · Cited by 4,632 · cited 2×
“However, inducers of TEI in microbial-rich versus “sterile” tumors may be different (Hanahan and Coussens, 2012; Mantovani et al., 2008).”
Background
Flagged first, then by citations
Cited by
Sorted by citations
Items 801–900 of 1,001
Shinde, A., Chandak, N., Singh, J., Roy, M., Mane, M., Tang, X., Vasiyani, H., Currim, F., Gohel, D., Shukla, S., et al. (2023) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2023.12.018 · Cited by 25
Sirakawin, C., Lin, D., Zhou, Z., Wang, X., Kelleher, R., Huang, S., Long, W., Pires‐daSilva, A., Liu, Y., Wang, J., et al. (2023) · Aging Cell · doi:10.1111/acel.14064 · Cited by 24
Molecular mechanisms of tumour development in glioblastoma: an emerging role for the circadian clock
Nelson, N., & Relógio, A. (2024) · npj Precision Oncology · doi:10.1038/s41698-024-00530-z · Cited by 25
APOC1 is a prognostic biomarker associated with M2 macrophages in ovarian cancer
Yang, S., Du, J., Wang, W. J., Zhou, D., & Xi, X. (2024) · BMC Cancer · doi:10.1186/s12885-024-12105-z · Cited by 25
Wang, M., Yi, H., Zhan, Z., Feng, Z., Yang, G., Zheng, Y., & Zhang, D. (2024) · Aggregate · doi:10.1002/agt2.622 · Cited by 25
Brooks, R. T., Luedders, B. A., Wheeler, A. M., Johnson, T. M., Yang, Y., Roul, P., Ganti, A. K., Singh, N., Sauer, B. C., Cannon, G. W., et al. (2024) · Arthritis & Rheumatology · doi:10.1002/art.42961 · Cited by 25
The Evolutionary Forest of Pancreatic Cancer
Mullen, K. M., Hong, J., Attiyeh, M. A., Hayashi, A., Sakamoto, H., Kohutek, Z. A., McIntyre, C. A., Zhang, H., Makohon-Moore, A. P., Zucker, A., et al. (2024) · Cancer Discovery · doi:10.1158/2159-8290.cd-23-1541 · Cited by 26
Wang, L., Zhang, L., Ma, R., Zhang, Y., Chang, Q., & Yin, D. (2025) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaf053 · Cited by 26
A Critical Appraisal of the Utility of Targeting Therapy-Induced Senescence for Cancer Treatment
Saleh, T., Greenberg, E. F., Faber, A. C., Harada, H., & Gewirtz, D. A. (2025) · Cancer Research · doi:10.1158/0008-5472.can-24-2219 · Cited by 28
Probiotics in colorectal cancer prevention and therapy: mechanisms, benefits, and challenges
Morsli, D. S., Tbahriti, H. F., Rahli, F., Mahammi, F. Z., Nagdalian, A. A., Hemeg, H. A., Imran, M., Rauf, A., & Shariati, M. A. (2025) · Discover Oncology · doi:10.1007/s12672-025-01996-4 · Cited by 26
Spirito, A. D., Balkhi, S., Vivona, V., & Mortara, L. (2025) · Exploration of Targeted Anti-tumor Therapy · doi:10.37349/etat.2025.1002304 · Cited by 26
Zhang, H., Wu, X. Y., Xu, Z., Sun, Z., Zhu, M., Chen, W., & Miao, C. (2019) · Gynecologic Oncology · doi:10.1016/j.ygyno.2019.12.006 · Cited by 25
MicroRNA-Mediated Metabolic Shaping of the Tumor Microenvironment
Virga, F., Quirico, L., Cucinelli, S., Mazzone, M., Taverna, D., & Orso, F. (2021) · Cancers · doi:10.3390/cancers13010127 · Cited by 25
Tissue-specific control of galectin-1-driven circuits during inflammatory responses
Cutine, A. M., Bach, C. A., Veigas, F., Merlo, J. P., Laporte, L., Cocco, M. N. M., Massaro, M., Sarbia, N., Perrotta, R. M., Mahmoud, Y. D., et al. (2021) · Glycobiology · doi:10.1093/glycob/cwab007 · Cited by 28
Ciardiello, D., Famiglietti, V., Napolitano, S., Esposito, L., Pietrantonio, F., Avallone, A., Maiello, E., Cremolini, C., Troiani, T., Martinelli, E., et al. (2022) · Clinical Colorectal Cancer · doi:10.1016/j.clcc.2022.01.005 · Cited by 27
Frey, A., Martin, D., D’Cruz, L. A., Fokas, E., Rödel, C. M., & Fleischmann, M. (2022) · Biomedicines · doi:10.3390/biomedicines10030598 · Cited by 27
Kanwore, K., Kanwore, K., Adzika, G. K., Abiola, A. A., Guo, X., Kambey, P. A., Xia, Y., & Gao, D. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.831636 · Cited by 26
Gao, Y., Zhang, Z., Li, Y., Chen, S., Lu, J., Wu, L., Ma, Z., Hu, Y., & Zhang, G. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.834564 · Cited by 24
Okpara, E. S., Adedara, I. A., Guo, X., Klos, M., Farombi, E. O., & Han, S. (2022) · Toxicology Reports · doi:10.1016/j.toxrep.2022.09.001 · Cited by 27
Roles of Mitochondria in Oral Squamous Cell Carcinoma Therapy: Friend or Foe?
Bai, J., Wu, L., Wang, X., Wang, Y., Shang, Z., Jiang, E., & Shao, Z. (2022) · Cancers · doi:10.3390/cancers14235723 · Cited by 27
Hu, Y., Li, S., Xiao, H., Xiong, Y., Lu, X., Yang, X., Luo, W., Luo, J., Zhang, S., Cheng, Y., et al. (2023) · Cancer Medicine · doi:10.1002/cam4.5918 · Cited by 25
IDO1 and inflammatory neovascularization: bringing new blood to tumor-promoting inflammation
Muller, A. J., Mondal, A., Dey, S., & Prendergast, G. C. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1165298 · Cited by 25
Al‐Masri, A. A., & Ameén, F. (2023) · Journal of Functional Foods · doi:10.1016/j.jff.2023.105628 · Cited by 25
Zhao, Z., & Xu, L. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1253895 · Cited by 25
Mai, R., Lu, T.-L., Lu, R.-J., Zeng, C., Lian, F., Li, L., Wu, G., & Ye, J. (2024) · Journal of Inflammation Research · doi:10.2147/jir.s441623 · Cited by 26
Dysregulation of calcium homeostasis in cancer and its role in chemoresistance
Kumari, N., Pullaguri, N., Rath, S. N., Bajaj, A., Sahu, V., & Ealla, K. K. R. (2024) · Cancer Drug Resistance · doi:10.20517/cdr.2023.145 · Cited by 26
Exploring the Comprehensive Neuroprotective and Anticancer Potential of Afzelin
Kciuk, M., Garg, N., Dhankhar, S., Saini, M., Mujwar, S., Devi, S., Chauhan, S., Singh, T. G., Singh, R., Marciniak, B., et al. (2024) · Pharmaceuticals · doi:10.3390/ph17060701 · Cited by 30
Li, R., Song, Y., Zhou, L., Li, W., & Zhu, X. (2020) · OncoTargets and Therapy · doi:10.2147/ott.s240378 · Cited by 25
Ausoni, S., & Azzarello, G. (2020) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2020.598384 · Cited by 23
Lin, Z., Hua, G., & Hu, X. (2024) · Cancer Cell International · doi:10.1186/s12935-024-03481-4 · Cited by 31
Cell Therapy as Target Therapy against Colon Cancer Stem Cells
Garza Treviño, E. N., Quiroz Reyes, A. G., Rojas Murillo, J. A., de la Garza Kalife, D. A., Delgado Gonzalez, P., Islas, J. F., Estrada Rodriguez, A. E., & Gonzalez Villarreal, C. A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24098163 · Cited by 24
Xu, H.-Z., Lin, X., Xu, Y., Xue, H., Lin, S., & Xu, T. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1227150 · Cited by 27
Interleukin-1 receptor antagonist: An alternative therapy for cancer treatment
Zhang, F., Jiang, J., & Zheng, X. W. (2023) · Life Sciences · doi:10.1016/j.lfs.2023.122276 · Cited by 24
Balancing the Scales: The Dual Role of Interleukins in Bone Metastatic Microenvironments
Dawalibi, A., Alosaimi, A., & Mohammad, K. S. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25158163 · Cited by 28
Gut microbiota in inflammation and colorectal cancer: A potential Toolbox for Clinicians
Grellier, N., Severino, A., Archilei, S., Kim, J., Gasbarrini, A., Cammarota, G., Porcari, S., & Benech, N. (2024) · Best Practice & Research Clinical Gastroenterology · doi:10.1016/j.bpg.2024.101942 · Cited by 26
Association of combined lead, cadmium, and mercury with systemic inflammation
Obeng-Gyasi, E., & Obeng-Gyasi, B. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2024.1385500 · Cited by 24
Ma, P., Yuan, L., Jia, S., Zhou, Z., Xu, D., Huang, S., Meng, F., Zhang, Z., & Nan, Y. (2024) · Frontiers in Oncology · doi:10.3389/fonc.2024.1446328 · Cited by 26
Li, J., Zheng, J., Wang, P., & Lv, D. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1483855 · Cited by 24
Tumor-infiltrating immune cells state-implications for various breast cancer subtypes
Xu, T., Zhang, H., Yang, B. B., Qadir, J., Yuan, H., & Ye, T. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1550003 · Cited by 29
Rodríguez-Pérez, J., Andreu-Martínez, R., Daza, R., Fernández-Arroyo, L., Hernández-García, A., Díaz‐García, E., Cubillos‐Zapata, C., Lozano-Díez, A., Morales, A., Ramos, D., et al. (2025) · Antioxidants · doi:10.3390/antiox14070839 · Cited by 29
Triantaphyllopoulos, K. A., Ragia, N. D., Panagiotopoulou, M.-C. E., & Sourlingas, T. G. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26199498 · Cited by 30
Tao, Y., Shen, H., Liu, Y., Li, G., Huang, Z., & Liu, Y. (2020) · Carcinogenesis · doi:10.1093/carcin/bgaa058 · Cited by 24
Yu, Y., Gong, L., & Ye, J. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.00942 · Cited by 26
Notch-Inflammation Networks in Regulation of Breast Cancer Progression
Liubomirski, Y., & Ben‐Baruch, A. (2020) · Cells · doi:10.3390/cells9071576 · Cited by 24
Cao, X., Cui, J. T., Yu, T., Li, Z., & Zhao, G. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.01459 · Cited by 24
Macrophage migration inhibitory factor in the pathogenesis of leukemia (Review)
Luo, Y., Wang, X., Shen, J., & Yao, J. (2021) · International Journal of Oncology · doi:10.3892/ijo.2021.5242 · Cited by 24
Microbiome in drug resistance to colon cancer
Pandey, K. R., & Umar, S. (2021) · Current Opinion in Physiology · doi:10.1016/j.cophys.2021.100472 · Cited by 24
Denti, V., Mahajneh, A., Capitoli, G., Clerici, F., Piga, I., Pagani, L., Chinello, C., Bolognesi, M. M., Paglia, G., Galimberti, S., et al. (2021) · Metabolites · doi:10.3390/metabo11090599 · Cited by 24
The Emerging Roles of Long Noncoding RNAs as Hallmarks of Lung Cancer
Jiang, J., Lu, Y., Zhang, F., Huang, J., Ren, X., & Zhang, R. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.761582 · Cited by 24
Proteoglycan Endocan: A multifaceted therapeutic target in Cancer
Pan, K., Yang, Y., Lee, W.-J., Hua, K., & Chien, M. (2021) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2021.188672 · Cited by 24
Zhang, L., Yi, H., Chen, J., Li, H., Luo, Y., Cheng, T., Yang, H., Jiang, Z., & Pan, C. (2022) · BioMed Research International · doi:10.1155/2022/8316525 · Cited by 24
Belyaeva, V., Wachner, S., Gyoergy, A., Emtenani, S., Gridchyn, I., Akhmanova, M., Linder, M., Roblek, M., Sibilia, M. C., & Siekhaus, D. E. (2022) · PLoS Biology · doi:10.1371/journal.pbio.3001494 · Cited by 23
The Yin‐Yang roles of protease‐activated receptors in inflammatory signalling and diseases
Zhuo, X., Wu, Y., Fu, X., Liang, X., Xiang, Y., Li, J., Mao, C., & Jiang, Y. (2022) · FEBS Journal · doi:10.1111/febs.16406 · Cited by 25
Chu, P., Tzeng, Y. T., Tsui, K., Chu, C.-Y., & Li, C. (2022) · Aging · doi:10.18632/aging.203933 · Cited by 24
The ‘reversibility’ of chronic atrophic gastritis after the eradication of Helicobacter pylori
Yang, H., Zhou, X., & Hu, B. (2022) · Postgraduate Medicine · doi:10.1080/00325481.2022.2063604 · Cited by 27
Mai, R., Bai, T., Luo, X., & Wu, G. (2022) · BMC Gastroenterology · doi:10.1186/s12876-022-02328-4 · Cited by 26
Predictive value of neutrophil-to-lymphocyte ratio for distant metastasis in gastric cancer patients
Zhang, X., Wang, X., Li, W., Sun, T., Diao, D., & Dang, C. (2022) · Scientific Reports · doi:10.1038/s41598-022-14379-4 · Cited by 24
Zhou, B., Lu, J., Beck, J. D., MOSS, K. L., Prizment, A. E., Demmer, R. T., Rodriguez, K. A. P., Joshu, C. E., Michaud, D. S., & Platz, E. A. (2022) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-22-0601 · Cited by 24
Banna, G. L., Friedlaender, A., Tagliamento, M., Mollica, V., Cortellini, A., Rebuzzi, S. E., Prelaj, A., Naqash, A. R., Auclin, É., Garetto, L., et al. (2022) · Current Oncology Reports · doi:10.1007/s11912-022-01335-8 · Cited by 26
BTN3A: A Promising Immune Checkpoint for Cancer Prognosis and Treatment
Kone, A.-S., Ssi, S. A., Sahraoui, S., & Badou, A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232113424 · Cited by 25
Peng, Y., Yin, D., Li, X., Wang, K., Li, W., Huang, Y., Liu, X., Ren, Z., Yang, X., Zhang, Z., et al. (2023) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-023-04572-x · Cited by 24
Luo, D., Chen, X., Dai, Y., Kuang, F. L., Kang, M., Li, B., & Su, S. (2023) · International Journal of Surgery · doi:10.1097/js9.0000000000000332 · Cited by 24
The “sweet” path to cancer: focus on cellular glucose metabolism
Iacobini, C., Vitale, M., Pugliese, G., & Menini, S. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1202093 · Cited by 23
Jia, M., Lu, R., Liu, C., Zhou, X., Li, P., & Zhang, S. (2023) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.3c03355 · Cited by 24
Lipid metabolism analysis in esophageal cancer and associated drug discovery
Jiao, R., Jiang, W. B., Xu, K., Luo, Q., Wang, L., & Zhao, C. (2023) · Journal of Pharmaceutical Analysis · doi:10.1016/j.jpha.2023.08.019 · Cited by 25
Johnson, M. O., Bell, A., Lauing, K. L., Ladomersky, E., Zhai, L., Penco-Campillo, M., Shah, Y., Mauer, E. A., Xiu, J., Nicolaides, T. P., et al. (2023) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-23-0834 · Cited by 25
Kim, T. W. (2023) · Nutrients · doi:10.3390/nu15245092 · Cited by 24
The Past and Future of Inflammation as a Target to Cancer Prevention
Antonucci, L., & Karin, M. (2024) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-23-0423 · Cited by 26
Landscape of exosomes to modified exosomes: a state of the art in cancer therapy
Mirgh, D., Sonar, S., Ghosh, S., Adhikari, M. D., Subramaniyan, V., Gorai, S., & Anand, K. (2024) · RSC Advances · doi:10.1039/d4ra04512b · Cited by 26
Liu, P., Zhang, X., Li, Z., Wei, L., Qiu, P., Liu, C., Wu, Y., Yan, Q., & Ma, J. (2020) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2020.01.158 · Cited by 24
Ko, C., Fang, K., Hsu, C., Lee, Y., Chang, G., Huang, E. I., Tsai, M., & Tsai, Y. (2021) · Head & Neck · doi:10.1002/hed.26738 · Cited by 25
Identification and validation of an immune-related gene pairs signature for three urologic cancers
Xie, B., Li, K., Zhang, H., Lai, G., Li, D., & Zhong, X. (2022) · Aging · doi:10.18632/aging.203886 · Cited by 23
Kan, L. L., Chan, B. C.-L., Leung, P., & Wong, C. K. (2023) · Molecules · doi:10.3390/molecules28155804 · Cited by 24
Yang, X., & Wu, C. (2024) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2024.12410 · Cited by 23
Anti-Inflammatory and Cytotoxic Compounds Isolated from Plants of Euphorbia Genus
Rojas-Jiménez, S., Cisneros, M. G. V., Salinas-Sánchez, D. O., Pérez‐Ramos, J., Sánchez‐Pérez, L., Pérez‐Gutiérrez, S., & Campos‐Xolalpa, N. (2024) · Molecules · doi:10.3390/molecules29051083 · Cited by 23
Cao, X., Li, L., Hu, J., Zhu, S., Song, S., Kong, S., Zhou, L., & Huang, Y. (2024) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2024.109804 · Cited by 23
Chen, Q., Zhai, B., Li, J., Wang, H. Z., Liu, Z., Shi, R., Wu, H., Xu, Y., & Ji, S. (2024) · Scientific Reports · doi:10.1038/s41598-024-82976-6 · Cited by 23
Gut dysbiosis in cancer immunotherapy: microbiota-mediated resistance and emerging treatments
Eiman, L., Moazzam, K., Anjum, S., Kausar, H., Sharif, E. A. M., & Ibrahim, W. N. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1575452 · Cited by 28
Noman, A. M., Sultan, M. T., Zafar, S., Maaz, M., Mazhar, A., Hussain, M., Imran, M., Mujtaba, A., Hussain, M. T., Alsagaby, S. A., et al. (2025) · Food Science & Nutrition · doi:10.1002/fsn3.70936 · Cited by 23
Li, C., Zhou, S., Chen, S., Xu, Z., Xue, Q., Wang, H., Liu, T., Chen, W., Feng, J., Chen, J., et al. (2025) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2025.124458 · Cited by 23
Cancer vs. SARS-CoV-2 induced inflammation, overlapping functions, and pharmacological targeting
Subbarao, S. A. (2021) · Inflammopharmacology · doi:10.1007/s10787-021-00796-w · Cited by 24
Heterogeneity of Colorectal Cancer Progression: Molecular Gas and Brakes
Gaiani, F., Marchesi, F., Negri, F., Greco, L., Malesci, A., de’Angelis, G. L., & Laghi, L. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22105246 · Cited by 24
Salem, A. Z., Medhat, D., Fathy, S. A., Mohamed, M. R., El-Khayat, Z., & El‐Daly, S. M. (2021) · Molecular Biology Reports · doi:10.1007/s11033-021-06683-5 · Cited by 23
Wróblewska, J. P., Lach, M., Kulcenty, K. I., Galus, Ł., Suchorska, W. M., Rösel, D., Brábek, J., & Marszałek, A. (2021) · Cancers · doi:10.3390/cancers13133334 · Cited by 23
Doxycycline Attenuates Cancer Cell Growth by Suppressing NLRP3-Mediated Inflammation
Al-Saadi, A., Tezcan, G., Garanina, E. E., Hamza, S., McIntyre, A., Rizvanov, A. A., & Khaiboullina, S. F. (2021) · Pharmaceuticals · doi:10.3390/ph14090852 · Cited by 23
Han, T., Zuo, Z., Qu, M., Zhou, Y., Li, Q., & Wang, H. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.748993 · Cited by 24
Shiah, S., Chou, S.-T., & Chang, J. (2021) · Cancers · doi:10.3390/cancers13225604 · Cited by 26
Anticancer natural products targeting immune checkpoint protein network
Chun, K., Kim, D., Raut, P. K., & Surh, Y. (2021) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2021.11.006 · Cited by 24
Old is new again: Emergence of thromboembolic complications in cancer patients on immunotherapy
McCrae, K. R., Swaidani, S., Diaz-Montero, C. M., & Khorana, A. A. (2022) · Thrombosis Research · doi:10.1016/j.thromres.2022.01.006 · Cited by 23
Wu, H., Li, W., Hao, M., Wang, Y., Xue, L., Ju, C., & Zhang, C. (2022) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2022.114380 · Cited by 23
The RAGE/multiligand axis: a new actor in tumor biology
Armando Rojas, R., Schneider, I., Lindner, C., González, I., & Morales, M. A. (2022) · Bioscience Reports · doi:10.1042/bsr20220395 · Cited by 24
Zhang, G.-H. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.975762 · Cited by 22
The prospect of tumor microenvironment-modulating therapeutical strategies
Eulberg, D., Frömming, A., Lapid, K., Mangasarian, A., & Barak, A. F. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.1070243 · Cited by 24
Fan, R., Chen, Y., Xu, G., Pan, W. Q., Lv, Y., & Zhang, Z. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.996312 · Cited by 23
ETV7 reduces inflammatory responses in breast cancer cells by repressing the TNFR1/NF-κB axis
Meškytė, E. M., Pezzè, L., Bartolomei, L., Forcato, M., Bocci, I. A., Bertalot, G., Barbareschi, M., Oliveira‐Ferrer, L., Bisio, A., Bicciato, S., et al. (2023) · Cell Death and Disease · doi:10.1038/s41419-023-05718-y · Cited by 23
CBD Inhibits In Vivo Development of Human Breast Cancer Tumors
García-Morales, L., Mendoza-Rodríguez, M., Tapia-Ramı́rez, J., & Meza, I. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241713235 · Cited by 23
Zhang, M., Lu, Y., Sun, H., Hou, C., Zhou, Z., Liu, X., Zhou, Q., Li, Z., & Yin, Y. (2023) · Translational Oncology · doi:10.1016/j.tranon.2023.101804 · Cited by 23
Brazilin-Ce nanoparticles attenuate inflammation by de/anti-phosphorylation of IKKβ
Li, S., Wang, K., Jiang, K., Xing, D., Deng, R., Xu, Y., Ding, Y., Guan, H., Chen, L., Wang, D., et al. (2024) · Biomaterials · doi:10.1016/j.biomaterials.2023.122466 · Cited by 23
Yu, D.-W., Li, Q., Cheng, L., Yang, P., Sun, W., Peng, Y., Hu, J., Wu, J., Gong, J., & Zhong, G. (2021) · American Journal of Epidemiology · doi:10.1093/aje/kwab131 · Cited by 23
Inflammation and diet: Focus on mental and cognitive health
Hepsomali, P., & Coxon, C. (2022) · Advances in Clinical and Experimental Medicine · doi:10.17219/acem/152350 · Cited by 22
Metadata
- Authors
- Greten, F. R., & Grivennikov, S. I.
- Affiliations
- Goethe University Frankfurt (DE)
- Fox Chase Cancer Center (US)
- Corresponding author
- Greten, Florian R.
- Grivennikov, Sergei I.
- Venue
- Immunity
- Publisher
- Elsevier BV
- Published
- 2019-07
- Volume
- 51
- Issue
- 1
- Pages
- 27-41
- ISSN
- 1074-7613 (ISSN-L)
- PMC
- PMC6831096
- OpenAlex
- W2959497269
- Cited by
- 3,806
- References
- 178
- Citations by year
- 2026: 457 · 2025: 640 · 2024: 753 · 2023: 715 · 2022: 664 · 2021: 397 · 2020: 163 · 2019: 16
- FWCI
- 26.79
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Immunity (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (R01CA227629, CA218133)
- Pew Scholar in Biomedical Sciences
- US-Israel BSF
- NIH (P30 CA-006927)
- Georg-Speyer-Haus
- LOEWE Center Frankfurt Cancer Institute (III L 5 - 519/03/03.001 - (0015), FOR2438: Gr1916/11-1, SFB 815, 1177, 1292)
- German Federal Ministry of Health
- Ministry of Higher Education, Research and the Arts of the State of Hessen
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Immune cells in cancer
- Health Sciences › Medicine › Pharmacology (medical) › Inflammatory mediators and NSAID effects
- Health Sciences › Medicine › Oncology › Cancer Immunotherapy and Biomarkers
- Keywords
- tumor inflammation, tumor inflammatory microenvironment, carcinogenesis, tumor initiation, tumor progression, metastasis, tumor-stroma interactions, cellular plasticity, tissue homeostasis, tissue repair, cancer therapy
- MeSH terms
- Animals, Chronic Disease, Homeostasis, Humans, Infections, Inflammation, Neoplasms, Neovascularization, Pathologic, Wound Healing, Autoimmunity, Tumor Microenvironment, Carcinogenesis
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review