Inflammation in obesity, diabetes, and related disorders

Cites (422)

Items 201–400 of 415

1. Dynamic, M2-Like Remodeling Phenotypes of CD11c+ Adipose Tissue Macrophages During High-Fat Diet–Induced Obesity in Mice
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2. Quantitation, tissue distribution and proliferation kinetics of kupffer cells in normal rat liver
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3. Free Fatty Acids Induce a Proinflammatory Response in Islets via the Abundantly Expressed Interleukin-1 Receptor I
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4. Anakinra, a Recombinant Human Interleukin-1 Receptor Antagonist, Inhibits Apoptosis in Experimental Acute Myocardial Infarction
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5. Chronic tissue inflammation and metabolic disease
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6. IL-1 antagonism reduces hyperglycemia and tissue inflammation in the type 2 diabetic GK rat
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7. Salsalate Improves Glycemia and Inflammatory Parameters in Obese Young Adults
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8. Anti-Inflammatory Therapy With Canakinumab for the Prevention and Management of Diabetes
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9. Differential release of chromatin-bound IL-1α discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation
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10. Depletion of fat-resident Treg cells prevents age-associated insulin resistance
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11. Dapansutrile, an oral selective NLRP3 inflammasome inhibitor, for treatment of gout flares: an open-label, dose-adaptive, proof-of-concept, phase 2a trial
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12. β-cell loss and β-cell apoptosis in human type 2 diabetes are related to islet amyloid deposition
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13. Fructose stimulated de novo lipogenesis is promoted by inflammation
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14. Long-term treatment with interleukin-1β induces insulin resistance in murine and human adipocytes
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15. TNF-α Antagonism with Etanercept Decreases Glucose and Increases the Proportion of High Molecular Weight Adiponectin in Obese Subjects with Features of the Metabolic Syndrome
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16. LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes
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17. Predictors of Nonalcoholic Steatohepatitis and Advanced Fibrosis in Morbidly Obese Patients
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18. C-C Chemokine Receptor 2 (CCR2) Regulates the Hepatic Recruitment of Myeloid Cells That Promote Obesity-Induced Hepatic Steatosis
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19. Adipose Natural Killer Cells Regulate Adipose Tissue Macrophages to Promote Insulin Resistance in Obesity
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20. Anti-tumor necrosis factor-alpha blockade improves insulin resistance in patients with rheumatoid arthritis.
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21. M2 macrophages promote beta-cell proliferation by up-regulation of SMAD7
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22. Molecular aspects of fructose metabolism and metabolic disease
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23. MiR-690, an exosomal-derived miRNA from M2-polarized macrophages, improves insulin sensitivity in obese mice
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24. Mechanisms of hypoxia signalling: new implications for nephrology
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25. The disposal of an oral glucose load in patients with non-insulin-dependent diabetes
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26. Hematopoietic-Derived Galectin-3 Causes Cellular and Systemic Insulin Resistance
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27. Effects of Gevokizumab on Glycemia and Inflammatory Markers in Type 2 Diabetes
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28. Nonalcoholic Fatty Liver Disease in Severely Obese Subjects
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29. Ocular Anti-VEGF Therapy for Diabetic Retinopathy: The Role of VEGF in the Pathogenesis of Diabetic Retinopathy
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30. Adipose-resident group 1 innate lymphoid cells promote obesity-associated insulin resistance
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31. Use of Salsalate to Target Inflammation in the Treatment of Insulin Resistance and Type 2 Diabetes
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32. Testosterone and insulin resistance in the metabolic syndrome and T2DM in men
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33. Dietary fructose improves intestinal cell survival and nutrient absorption
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34. Pharmacologic Targeting of Hypoxia-Inducible Factors
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35. Metabolic and Vascular Effects of Tumor Necrosis Factor-α Blockade with Etanercept in Obese Patients with Type 2 Diabetes
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36. Senescent vascular smooth muscle cells drive inflammation through an interleukin-1α-dependent senescence-associated secretory phenotype
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37. Skeletal muscle insulin resistance: role of mitochondria and other ROS sources
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38. Monounsaturated Fatty Acid–Enriched High-Fat Diets Impede Adipose NLRP3 Inflammasome–Mediated IL-1β Secretion and Insulin Resistance Despite Obesity
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39. Expansion of Islet-Resident Macrophages Leads to Inflammation Affecting β Cell Proliferation and Function in Obesity
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40. Hepatocyte-derived extracellular vesicles promote endothelial inflammation and atherogenesis via microRNA-1
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41. The Pathophysiological Role of Microglia in Dynamic Surveillance, Phagocytosis and Structural Remodeling of the Developing CNS
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42. Hyperphosphorylation of Tau Associates With Changes in Its Function Beyond Microtubule Stability
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43. Disruption of Hypoxia-Inducible Factor 1 in Adipocytes Improves Insulin Sensitivity and Decreases Adiposity in High-Fat Diet–Fed Mice
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44. Connective tissue growth factor: a fibrogenic master switch in fibrotic liver diseases
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45. Inducible MicroRNA-223 Down-Regulation Promotes TLR-Triggered IL-6 and IL-1β Production in Macrophages by Targeting STAT3
    Qingyun Chen, Hui Wang, Yang Liu, Yinjing Song, Lihua Lai, Quan Han, Xuetao Cao, Qingqing Wang · 2012 · PLoS ONE
46. Interorgan communication by exosomes, adipose tissue, and adiponectin in metabolic syndrome
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47. Microglial activation correlates in vivo with both tau and amyloid in Alzheimer’s disease
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48. Skeletal muscle insulin resistance: role of inflammatory cytokines and reactive oxygen species
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49. Effects of Etanercept in Patients With the Metabolic Syndrome
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50. Diabetic nephropathy – is this an immune disorder?
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51. Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress
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52. TREM2and Neurodegenerative Disease
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53. Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity
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54. Blocking IL-6 trans-signaling prevents high-fat diet-induced adipose tissue macrophage recruitment but does not improve insulin resistance
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55. Effects of infliximab treatment on insulin resistance in patients with rheumatoid arthritis and ankylosing spondylitis
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56. T Cell–Derived IL-22 Amplifies IL-1β–Driven Inflammation in Human Adipose Tissue: Relevance to Obesity and Type 2 Diabetes
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57. Leptin modulates β cell expression of IL-1 receptor antagonist and release of IL-1β in human islets
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58. Salicylate (Salsalate) in Patients With Type 2 Diabetes: A Randomized Trial
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59. Preclinical Models for Studying NASH-Driven HCC: How Useful Are They?
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60. Diet-induced obesity in mice causes changes in immune responses and bone loss manifested by bacterial challenge
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61. Interleukin-1 Blockade in Recently Decompensated Systolic Heart Failure
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62. Mechanisms of Alzheimer’s Disease Pathogenesis and Prevention: The Brain, Neural Pathology, N-methyl-D-aspartate Receptors, Tau Protein and Other Risk Factors
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63. Local proliferation of macrophages in adipose tissue during obesity-induced inflammation
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64. Increased Immune Cell Infiltration of the Exocrine Pancreas: A Possible Contribution to the Pathogenesis of Type 1 Diabetes
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65. Islet-associated macrophages in type 2 diabetes
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66. The dynamics of monocytes and microglia in Alzheimer’s disease
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67. Myokines in insulin resistance and type 2 diabetes
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68. Selective Inhibition of Hypoxia-Inducible Factor 1α Ameliorates Adipose Tissue Dysfunction
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69. Emerging Biomarkers, Tools, and Treatments for Diabetic Polyneuropathy
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70. Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes
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71. Muscle inflammatory response and insulin resistance: synergistic interaction between macrophages and fatty acids leads to impaired insulin action
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72. Microglia and CNS Interleukin-1: Beyond Immunological Concepts
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73. Islet inflammation in type 2 diabetes
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74. Lipid-Induced Hepatocyte-Derived Extracellular Vesicles Regulate Hepatic Stellate Cells via MicroRNA Targeting Peroxisome Proliferator-Activated Receptor-γ
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75. Islet Inflammation and Fibrosis in a Spontaneous Model of Type 2 Diabetes, the GK Rat
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76. No Increased Insulin Sensitivity after a Single Intravenous Administration of a Recombinant Human Tumor Necrosis Factor Receptor: Fc Fusion Protein in Obese Insulin-Resistant Patients
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77. The Role of Inflammation in β-cell Dedifferentiation
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78. Intestinal Dendritic Cells in Health and Gut Inflammation
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79. Gut-associated IgA+ immune cells regulate obesity-related insulin resistance
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80. Colonic Pro-inflammatory Macrophages Cause Insulin Resistance in an Intestinal Ccl2/Ccr2-Dependent Manner
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81. Reciprocal control of inflammatory cytokines, IL-1 and IL-6, and β-amyloid production in cultures
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82. Pro‐Inflammatory macrophages increase in skeletal muscle of high fat‐Fed mice and correlate with metabolic risk markers in humans
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83. Portal fibrosis and hepatic steatosis in morbidly obese subjects: A spectrum of nonalcoholic fatty liver disease
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84. Amyloid β and Amylin Fibrils Induce Increases in Proinflammatory Cytokine and Chemokine Production by THP‐1 Cells and Murine Microglia
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85. Lack of Interleukin-1 Receptor I (IL-1RI) Protects Mice From High-Fat Diet–Induced Adipose Tissue Inflammation Coincident With Improved Glucose Homeostasis
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86. Effect of extracellular vesicles of human adipose tissue on insulin signaling in liver and muscle cells
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87. Adipose Type One Innate Lymphoid Cells Regulate Macrophage Homeostasis through Targeted Cytotoxicity
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88. Type I Interferon Responses Drive Intrahepatic T Cells to Promote Metabolic Syndrome
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89. Roles of Chemokines and Chemokine Receptors in Obesity-Associated Insulin Resistance and Nonalcoholic Fatty Liver Disease
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90. Double-Blind, Randomized Study Evaluating the Glycemic and Anti-inflammatory Effects of Subcutaneous LY2189102, a Neutralizing IL-1β Antibody, in Patients With Type 2 Diabetes
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91. “Sweet death”: Fructose as a metabolic toxin that targets the gut-liver axis
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92. Phase 1B, Randomized, Double-Blinded, Dose Escalation, Single-Center, Repeat Dose Safety and Pharmacodynamics Study of the Oral NLRP3 Inhibitor Dapansutrile in Subjects With NYHA II–III Systolic Heart Failure
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93. Adipose Tissue Hypoxia, Inflammation, and Fibrosis in Obese Insulin-Sensitive and Obese Insulin-Resistant Subjects
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94. Intermuscular and perimuscular fat expansion in obesity correlates with skeletal muscle T cell and macrophage infiltration and insulin resistance
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95. Deficiency of the Leukotriene B4 Receptor, BLT-1, Protects against Systemic Insulin Resistance in Diet-Induced Obesity
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96. Fasting and refeeding differentially regulate NLRP3 inflammasome activation in human subjects
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97. Spatial and Temporal Mapping of Human Innate Lymphoid Cells Reveals Elements of Tissue Specificity
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98. Characterization of Distinct Subpopulations of Hepatic Macrophages in HFD/Obese Mice
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99. Overexpression of Il6 leads to hyperinsulinaemia, liver inflammation and reduced body weight in mice
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