The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Alterations in left ventricular structure and function in young healthy obese women
Open accessAbstract
Objectives This study was designed to determine the effects of obesity on left ventricular (LV) structure and function in young obese women.Background Severe prolonged obesity in older adults results in increased plasma volume, eccentric LV hypertrophy, and systolic and diastolic dysfunction. Obese women are at increased risk for the development of heart failure. However, the effects of the obesity on cardiac structure and function in young, otherwise-healthy women are controversial.Methods Fifty-one women were evaluated: 20 were obese (body mass index [BMI] > or =30 kg/m(2)) and 31 were non-obese (BMI <30 kg/m(2)). Left ventricular structure and systolic and diastolic function were assessed by two-dimensional echocardiography and tissue Doppler imaging, including the load-independent systolic myocardial velocity (Sm global) and early diastolic myocardial velocity (Em global), respectively. The effects of BMI on LV structure and function were assessed using multivariate regression analyses.Results Obese women had higher end-diastolic septal and posterior wall thickness, LV mass, and relative wall thickness than non-obese women; BMI values showed significant correlations with these variables (r = 0.58, p < 0.0001; r = 0.50, p < 0.0002; r = 0.52, p < 0.0001, and r = 0.40, p < 0.005, respectively). The Sm global and Em global were lower in obese women, suggesting systolic and diastolic function are decreased; both were negatively correlated with BMI (r = -0.43, p <. 002 and r = -0.61, p < 0.0001, respectively). Multivariate analysis showed BMI was the only independent predictor of relative wall thickness, Sm global, and Em global.Conclusions Obesity in young otherwise-healthy women is associated with concentric LV remodeling and decreased systolic and diastolic function. These early abnormalities in LV structure and function may have important implications for explaining the myocardial dysfunction that is associated with increased cardiovascular morbidity and mortality caused by obesity.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“In addition, the results indicate that both LV cavity size and wall thickness are increased in obese subjects compared with age-matched controls (22, 134, 151, 156, 242, 279, 377).”
From Cardiac remodeling in obesity (2008) · cites this paper as [279]
In the citing paper
“Many published studies have concluded that obesity is independently associated with LV hypertrophy (22, 28, 63, 72, 116, 235, 242, 266, 279, 284, 377).”
From Cardiac remodeling in obesity (2008) · cites this paper as [279]
In the citing paper
“The more recent data confirm the increased prevalence of LV hypertrophy in obese subjects.”
From Cardiac remodeling in obesity (2008) · cites this paper as [279]
In the citing paper
“Indeed, obese subjects have generally been found to have subclinical contractile abnormalities when assessed with the aforementioned techniques (21, 22, 71, 279, 377).”
From Cardiac remodeling in obesity (2008) · cites this paper as [279]
In the citing paper
“Similarly, E-wave deceleration times have been reported to be increased (274) or unchanged (279) in obese subjects.”
From Cardiac remodeling in obesity (2008) · cites this paper as [279]
In the citing paper
“Various authors have reported depressed LV ejection fraction (EF) (15, 68, 100), normal EF (22, 111, 116, 191, 242, 266, 279, 377), and supernormal EF (28, 155, 274, 375) in obese subjects.”
From Cardiac remodeling in obesity (2008) · cites this paper as [279]
In the citing paper
“More recently, however, several studies have found that LV ejection fraction is normal or even supranormal in the majority of obese subjects, even those with severe obesity (22, 28, 155, 191, 242, 274, 279, 375, 377).”
From Cardiac remodeling in obesity (2008) · cites this paper as [279]
In the citing paper
“Some studies have found reduced early diastolic (E-wave) velocities (155) while others have found them to be unchanged (242, 266, 274, 279, 314).”
From Cardiac remodeling in obesity (2008) · cites this paper as [279]
In the citing paper
“Using these approaches, at least two groups have reported evidence of reduced early diastolic tissue velocities and diastolic strain rate in obese compared with normal-weight subjects (279, 377).”
From Cardiac remodeling in obesity (2008) · cites this paper as [279]
In the citing paper
“Lastly, late diastolic (A-wave) velocities have been reported to be increased (28, 155, 242) or unchanged (266, 274, 279, 314).”
From Cardiac remodeling in obesity (2008) · cites this paper as [279]
In the citing paper
“Unfortunately, this relatively straightforward and logical hypothesis is complicated by the fact that multiple recent studies have shown a predominance of concentric geometry in obese patients (22, 63, 72, 279, 377).”
From Cardiac remodeling in obesity (2008) · cites this paper as [279]
Citations
Cites
Recommendations for Quantitation of the Left Ventricle by Two-Dimensional Echocardiography
Schiller, N. B., Shah, P. M., Crawford, M., DeMaria, A. N., Devereux, R. B., Feigenbaum, H., Gutgesell, H. P., Reichek, N., Sahn, D. J., Schnittger, I., et al. (1989) · Journal of the American Society of Echocardiography · doi:10.1016/s0894-7317(89)80014-8 · Cited by 8,110
Obesity and the risk of heart failure
Kenchaiah, S., Evans, J. C., Levy, D., Wilson, P. W. F., Benjamin, E. J., Larson, M. G., Kannel, W. B., & Vasan, R. S. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa020245 · Cited by 3,093
Quiñones, M. A., Otto, C. M., Stoddard, M. F., Waggoner, A. D., & Zoghbi, W. A. (2002) · Journal of the American Society of Echocardiography · doi:10.1067/mje.2002.120202 · Cited by 2,132
Self-citationAnnual Deaths Attributable to Obesity in the United States
Allison, D. B. (1999) · JAMA · doi:10.1001/jama.282.16.1530 · Cited by 1,863
Sohn, D., Chai, I.-H., Lee, D., Kim, H. C., Kim, H.-S., Oh, B., Lee, M.-M., Park, Y.-B., Choi, Y., Seo, J. D., et al. (1997) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(97)88335-0 · Cited by 1,555
Nishimura, R. A., & Tajik, A. J. (1997) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(97)00144-7 · Cited by 1,257
Obesity cardiomyopathy: pathophysiology and evolution of the clinical syndrome
Alpert, M. A. (2001) · The American Journal of the Medical Sciences · doi:10.1097/00000441-200104000-00003 · Cited by 795
Prognosis of left ventricular geometric patterns in the Framingham heart study
Krumholz, H. M., Larson, M. G., & Levy, D. A. (1995) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(94)00473-4 · Cited by 537
Wang, M., Yip, G. W., Wang, A. Y.-M., Zhang, Y., Ho, P. Y., Tse, M. K., Lam, P. K. W., & Sanderson, J. E. (2003) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(02)02921-2 · Cited by 428
Verdecchia, P., Schillaci, G., Borgioni, C., Ciucci, A., Battistelli, M., Bartoccini, C., Santucci, A., Santucci, C., Reboldi, G., & Porcellati, C. (1995) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(94)00424-o · Cited by 408
Flagged first, then by citations
Research works printed but not linked: 1
- Alpert, 1995, Relation of duration of morbid obesity to left ventricular mass, systolic function, and diastolic filling, and effect of weight loss, Am J Cardiol, 76, 1194, 10.1016/S0002-9149(99)80338-5 · DOI · Paper page
Cited by
Sorted by citations
Poirier, P., Giles, T. D., Bray, G. A., Hong, Y., Stern, J. S., Pi-Sunyer, F. X., & Eckel, R. H. (2006) · Circulation · doi:10.1161/circulationaha.106.171016 · Cited by 3,165
Myocardial Fatty Acid Metabolism in Health and Disease
Lopaschuk, G. D., Ussher, J. R., Folmes, C. D. L., Jaswal, J. S., & Stanley, W. C. (2010) · Physiological Reviews · doi:10.1152/physrev.00015.2009 · Cited by 2,228
Klein, S., Burke, L. E., Bray, G. A., Blair, S., Allison, D. B., Pi-Sunyer, X., Hong, Y., & Eckel, R. H. (2004) · Circulation · doi:10.1161/01.cir.0000145546.97738.1e · Cited by 934
Abel, E. D., Litwin, S. E., & Sweeney, G. (2008) · Physiological Reviews · doi:10.1152/physrev.00017.2007 · Cited by 736
Alterations of Left Ventricular Myocardial Characteristics Associated With Obesity
Wong, C. Y., O’Moore-Sullivan, T., Leano, R., Byrne, N., Beller, E., & Marwick, T. H. (2004) · Circulation · doi:10.1161/01.cir.0000147184.13872.0f · Cited by 713
Peterson, L. R., Herrero, P., Schechtman, K. B., Racette, S. B., Waggoner, A. D., Kisrieva-Ware, Z., Dence, C., Klein, S., Marsala, J., Meyer, T., et al. (2004) · Circulation · doi:10.1161/01.cir.0000127959.28627.f8 · Cited by 656
Self-citationCardiovascular consequences of metabolic syndrome
Tune, J. D., Goodwill, A. G., Sassoon, D., & Mather, K. J. (2017) · Translational research · doi:10.1016/j.trsl.2017.01.001 · Cited by 645
Impact of Obesity and the Obesity Paradox on Prevalence and Prognosis in Heart Failure
Lavie, C. J., Alpert, M., Arena, R. A., Mehra, M. R., Milani, R. V., & Ventura, H. O. (2013) · JACC Heart Failure · doi:10.1016/j.jchf.2013.01.006 · Cited by 617
The medical complications of obesity
Malnick, S. D. H. (2006) · QJM · doi:10.1093/qjmed/hcl085 · Cited by 579
The pathophysiology of hypertension in patients with obesity
DeMarco, V. G., Aroor, A. R., & Sowers, J. R. (2014) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2014.44 · Cited by 545
Altered Respiratory Physiology in Obesity
Parameswaran, K., Todd, D. C., & Soth, M. (2006) · Canadian Respiratory Journal · doi:10.1155/2006/834786 · Cited by 527
Boudina, S., Sena, S., O’Neill, B. T., Tathireddy, P., Young, M. E., & Abel, E. D. (2005) · Circulation · doi:10.1161/circulationaha.105.554360 · Cited by 502
Transgenic Expression of Fatty Acid Transport Protein 1 in the Heart Causes Lipotoxic Cardiomyopathy
Chiu, H.-C., Kovács, A. D., Blanton, R. M., Han, X., COURTOIS, M. R., Weinheimer, C. J., Yamada, K. A., Brunet, S., Xu, H., Nerbonne, J. M., et al. (2004) · Circulation Research · doi:10.1161/01.res.0000154079.20681.b9 · Cited by 470
Childhood Obesity and Cardiovascular Dysfunction
Coté, A. T., Harris, K. C., Panagiotopoulos, C., Sandor, G. G. S., & Devlin, A. M. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.07.042 · Cited by 456
Borlaug, B. A., Jensen, M. D., Kitzman, D. W., Lam, C. S. P., Obokata, M., & Rider, O. J. (2023) · Cardiovascular Research · doi:10.1093/cvr/cvac120 · Cited by 450
Role of changes in cardiac metabolism in development of diabetic cardiomyopathy
An, D., & Rodrigues, B. B. (2006) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00278.2006 · Cited by 449
Adiposity of the Heart*, Revisited
McGavock, J., Victor, R. G., Unger, R. H., & Szczepaniak, L. S. (2006) · Annals of Internal Medicine · doi:10.7326/0003-4819-144-7-200604040-00011 · Cited by 391
Obesity cardiomyopathy: evidence, mechanisms, and therapeutic implications
Ren, J. T., Wu, N. N., Wang, S., Sowers, J. R., & Zhang, Y. (2021) · Physiological Reviews · doi:10.1152/physrev.00030.2020 · Cited by 388
Effect of Obesity and Overweight on Left Ventricular Diastolic Function
Russo, C., Jin, Z., Homma, S., Rundek, T., Elkind, M. S. V., Sacco, R. L., & Di Tullio, M. R. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2010.10.042 · Cited by 361
The Impact of Obesity on the Left Ventricle
Turkbey, E. B., McClelland, R. L., Kronmal, R. A., Burke, G. L., Bild, D. E., Tracy, R. P., Arai, A. E., Lima, J. A. C., & Bluemke, D. A. (2010) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2009.10.012 · Cited by 352
Cardiac Energy Metabolism in Obesity
Lopaschuk, G. D., Folmes, C. D. L., & Stanley, W. C. (2007) · Circulation Research · doi:10.1161/circresaha.107.150417 · Cited by 309
Effects of Obesity on Cardiovascular Hemodynamics, Cardiac Morphology, and Ventricular Function
Alpert, M., Omran, J., & Bostick, B. P. (2016) · Current Obesity Reports · doi:10.1007/s13679-016-0235-6 · Cited by 301
Obesity and Heart Failure: Focus on the Obesity Paradox
Carbone, S., Lavie, C. J., & Arena, R. A. (2017) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2016.11.001 · Cited by 298
Habibi, J., Aroor, A. R., Sowers, J. R., Jia, G., Hayden, M. R., Garro, M., Barron, B. J., Mayoux, E., Rector, R. S., Whaley‐Connell, A. T., et al. (2017) · Cardiovascular Diabetology · doi:10.1186/s12933-016-0489-z · Cited by 267
Obesity and heart failure: epidemiology, pathophysiology, clinical manifestations, and management
Alpert, M., Lavie, C. J., Agrawal, H., Aggarwal, K. B., & Kumar, S. (2014) · Translational research · doi:10.1016/j.trsl.2014.04.010 · Cited by 258
Mizuguchi, Y., Oishi, Y., Miyoshi, H., Íuchi, A., Nagase, N., & Oki, T. (2008) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2008.07.016 · Cited by 245
Brown, A. J. M., Gandy, S. J., McCrimmon, R. J., Houston, J. G., Struthers, A. D., & Lang, C. C. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehaa419 · Cited by 245
Impact of Obesity and Weight Loss on Cardiac Performance and Morphology in Adults
Alpert, M., Omran, J., Mehra, A., & Ardhanari, S. (2013) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2013.09.003 · Cited by 243
Maladaptive immune and inflammatory pathways lead to cardiovascular insulin resistance
Aroor, A. R., McKarns, S. C., DeMarco, V. G., Jia, G., & Sowers, J. R. (2013) · Metabolism · doi:10.1016/j.metabol.2013.07.001 · Cited by 243
Obesity cardiomyopathy: pathogenesis and pathophysiology
Wong, C. Y., & Marwick, T. H. (2007) · Nature Clinical Practice Cardiovascular Medicine · doi:10.1038/ncpcardio0943 · Cited by 243
Daimon, M., Watanabe, H., Abe, Y., Hirata, K., Hozumi, T., Ishii, K., Ito, H., Iwakura, K., Izumi, C., Matsuzaki, M., et al. (2008) · Circulation Journal · doi:10.1253/circj.cj-08-0171 · Cited by 233
Avelar, E., Cloward, T. V., Walker, J. M., Farney, R. J., Strong, M., Pendleton, R. C., Segerson, N., Adams, T. D., Gress, R. E., Hunt, S. C., et al. (2007) · Hypertension · doi:10.1161/01.hyp.0000251711.92482.14 · Cited by 228
Obesity and Cardiac Remodeling in Adults: Mechanisms and Clinical Implications
Alpert, M. A., Karthikeyan, K., Abdullah, O., & Ghadban, R. (2018) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2018.07.012 · Cited by 221
Cardiorespiratory Fitness and Short-term Complications After Bariatric Surgery
McCullough, P. A., Gallagher, M. J., deJong, A., Sandberg, K. R., Trivax, J. E., Alexander, D., Kasturi, G. C., Jafri, S. M. A., Krause, K. R., Chengelis, D. L., et al. (2006) · CHEST Journal · doi:10.1378/chest.130.2.517 · Cited by 222
Management of cardiovascular diseases in patients with obesity
Lavie, C. J., Arena, R., Alpert, M. A., Milani, R. V., & Ventura, H. O. (2018) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2017.108 · Cited by 218
Aessopos, A., Farmakis, D. T., Deftereos, S., Tsironi, M., Tassiopoulos, S. T., Moyssakis, I. E., & Karagiorga, M. (2005) · CHEST Journal · doi:10.1378/chest.127.5.1523 · Cited by 216
Aurigemma, G. P., SIMONE, G. D., & Fitzgibbons, T. P. (2013) · Circulation Cardiovascular Imaging · doi:10.1161/circimaging.111.964627 · Cited by 214
Lambert, E., Sari, C. I., Dawood, T., Nguyen, J., McGrane, M., Eikelis, N., Chopra, R., Wong, C., Chatzivlastou, K., Head, G., et al. (2010) · Hypertension · doi:10.1161/hypertensionaha.110.155663 · Cited by 209
Role of estrogen in diastolic dysfunction
Zhao, Z., Wang, H., Jessup, J. A., Lindsey, S. H., Chappell, M. C., & Groban, L. (2014) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00859.2013 · Cited by 209
Lifetime risk: childhood obesity and cardiovascular risk
Ayer, J. G., Charakida, M., Deanfield, J. E., & Celermajer, D. S. (2015) · European Heart Journal · doi:10.1093/eurheartj/ehv089 · Cited by 191
The Obesity Paradox: Fact or Fiction?
Habbu, A., Lakkis, N. M., & Dokainish, H. (2006) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2006.04.039 · Cited by 184
Fuentes, L. D. L., Brown, A. L., Mathews, S. J., Waggoner, A. D., Soto, P. F., Gropler, R. J., & Dávila‐Román, V. G. (2006) · European Heart Journal · doi:10.1093/eurheartj/ehl526 · Cited by 176
Self-citationRider, O. J., Apps, A. P., Miller, J. J. J. J., Lau, J. Y. C., Lewis, A., Peterzan, M. A., Dodd, M. S., Lau, A. Z., Trumper, C., Gallagher, F. A., et al. (2020) · Circulation Research · doi:10.1161/circresaha.119.316260 · Cited by 172
Ciccarelli, M., Chuprun, J. K., Rengo, G., Gao, E., Wei, Z., Peroutka, R. J., Gold, J. I., Gumpert, A. M., Chen, M., Otis, N. J., et al. (2011) · Circulation · doi:10.1161/circulationaha.110.988642 · Cited by 171
Ernande, L., Rietzschel, E. R., Bergerot, C., Buyzere, M. D., Schnell, F., Groisne, L., Ovize, M., Croisille, P., Moulin, P., Gillebert, T. C., et al. (2010) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2010.09.007 · Cited by 169
Impact of Gender on the Myocardial Metabolic Response to Obesity
Peterson, L. R., Soto, P. F., Herrero, P., Mohammed, B. S., Avidan, M. S., Schechtman, K. B., Dence, C. S., & Gropler, R. J. (2008) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2008.05.004 · Cited by 163
Self-citationGoland, S., Shimoni, S., Zornitzki, T., Knobler, H., Azoulai, O., Lutaty, G., Melzer, E., Orr, A., Caspi, A., & Malnick, S. D. H. (2006) · Journal of Clinical Gastroenterology · doi:10.1097/01.mcg.0000225668.53673.e6 · Cited by 163
von Bibra, H., & Sutton, M. S. J. (2010) · Diabetologia · doi:10.1007/s00125-010-1682-3 · Cited by 158
Wilson, C. R., Tran, M. K., Salazar, K. L., Young, M. E., & Taegtmeyer, H. (2007) · Biochemical Journal · doi:10.1042/bj20070392 · Cited by 156
Goudis, C. A., Korantzopoulos, P. G., Ntalas, I. V., Kallergis, E. M., & Ketikoglou, D. G. (2015) · Journal of Cardiology · doi:10.1016/j.jjcc.2015.04.002 · Cited by 154
Pericardial, But Not Hepatic, Fat by CT Is Associated With CV Outcomes and Structure
Shah, R. V., Anderson, A. M., Ding, J., Budoff, M. J., Rider, O. J., Petersen, S. E., Jensen, M. K., Koch, M., Allison, M., Kawel‐Boehm, N., et al. (2017) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2016.10.024 · Cited by 153
Woodiwiss, A. J., Libhaber, C. D., Majane, O. H. I., Libhaber, E., Maseko, M. J., & Norton, G. R. (2008) · American Journal of Hypertension · doi:10.1038/ajh.2008.252 · Cited by 151
Cardiac structure and function are altered in adults with non-alcoholic fatty liver disease
Hallsworth, K., Hollingsworth, K. G., Thoma, C., Jakovljević, D. G., MacGowan, G. A., Anstee, Q. M., Taylor, R., Day, C. P., & Trenell, M. I. (2012) · Journal of Hepatology · doi:10.1016/j.jhep.2012.11.015 · Cited by 149
Fuentes, L. D. L., Waggoner, A. D., Mohammed, B. S., Stein, R. I., Miller, B. V., Foster, G. D., Wyatt, H. R., Klein, S. B., & Dávila‐Román, V. G. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.07.054 · Cited by 146
Self-citationClinical Phenotypes in Heart Failure With Preserved Ejection Fraction
Samson, R., Jaiswal, A., Ennezat, P. V., Cassidy, M. M., & Jemtel, T. H. L. (2016) · Journal of the American Heart Association · doi:10.1161/jaha.115.002477 · Cited by 149
Effects of Catecholamine Stress on Diastolic Function and Myocardial Energetics in Obesity
Rider, O. J., Francis, J. M., Ali, M. K., Holloway, C. J., Pegg, T. J., Robson, M. D., Tyler, D. J., Byrne, J. P., Clarke, K., & Neubauer, S. (2012) · Circulation · doi:10.1161/circulationaha.111.069518 · Cited by 143
Manifestations and mechanisms of myocardial lipotoxicity in obesity
Sletten, A. C., Peterson, L. R., & Schaffer, J. E. (2018) · Journal of Internal Medicine · doi:10.1111/joim.12728 · Cited by 148
Self-citationReddy, Y. N. V., Lewis, G. D., Shah, S. J., Obokata, M., Abou-Ezzedine, O. F., Fudim, M., Sun, J.-L., Chakraborty, H., McNulty, S., LeWinter, M. M., et al. (2019) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2018.11.037 · Cited by 141
Favorable Changes in Cardiac Geometry and Function Following Gastric Bypass Surgery
Owan, T., Avelar, E., Morley, K., Jiji, R. S., Hall, N. L., Krezowski, J. T., Gallagher, J., Williams, Z., Preece, K., Gundersen, N., et al. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2010.10.017 · Cited by 142
Obesity and Pulmonary Hypertension: A Review of Pathophysiologic Mechanisms
Friedman, S. E., & Andrus, B. W. (2012) · Journal of Obesity · doi:10.1155/2012/505274 · Cited by 130
Dhuper, S., Abdullah, R. A., Weichbrod, L., Mahdi, E. S., & Cohen, H. W. (2010) · Obesity · doi:10.1038/oby.2010.134 · Cited by 127
Cardiac remodeling in a rat model of diet-induced obesity
Leopoldo, A. S., Sugizaki, M. M., Lima‐Leopoldo, A. P., do Nascimento, A. F., Luvizotto, R. D. A. M., de Campos, D. H. S., Okoshi, K., Dal‐Pai‐Silva, M., Padovani, C. R., & Cicogna, A. C. (2010) · Canadian Journal of Cardiology · doi:10.1016/s0828-282x(10)70440-2 · Cited by 129
Obesity and Cardiovascular Disease
Obeng-Gyimah, E. K., & Sam, F. (2014) · Humana Press eBooks · doi:10.1007/978-1-62703-770-9_18 · Cited by 126
Chen, D., Li, X., Zhang, L., Zhu, M., & Gao, L. (2018) · Journal of Cellular Biochemistry · doi:10.1002/jcb.27068 · Cited by 125
Adaptation and maladaptation of the heart in obesity
Harmancey, R., Wilson, C. R., & Taegtmeyer, H. (2008) · Hypertension · doi:10.1161/hypertensionaha.108.110031 · Cited by 121
Russo, C. A., Jin, Z., Homma, S., Rundek, T., Elkind, M. S. V., Sacco, R. L., & Tullio, M. R. D. (2010) · European Journal of Heart Failure · doi:10.1093/eurjhf/hfq022 · Cited by 116
Impact of obesity on cardiac metabolism, fibrosis, and function
Mahajan, R., Lau, D. H., & Sanders, P. (2014) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2014.09.005 · Cited by 109
Manrique, C. M., DeMarco, V. G., Aroor, A. R., Mugerfeld, I., Garro, M., Habibi, J., Hayden, M. R., & Sowers, J. R. (2013) · Endocrinology · doi:10.1210/en.2013-1256 · Cited by 106
Fotbolcu, H., Yakar, T., Duman, D., Karaahmet, T., Tigen, K., Çevik, C., Kurtoğlu, Ü., & Dindar, İ. (2010) · PubMed · Cited by 104
Arnold, J. M. O., Howlett, J. G., Ducharme, A., Ezekowitz, J. A., Gardner, M. J., Giannetti, N., Haddad, H. A., Heckman, G. A., Isaac, D., Jong, P., et al. (2008) · Canadian Journal of Cardiology · doi:10.1016/s0828-282x(08)70545-2 · Cited by 103
Pagé, A., Dumesnil, J. G., Clavel, M.-A., Chan, K. L., Teo, K. K., Tam, J. W., Mathieu, P., Després, J.-P., & Pibarot, P. (2010) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.11.083 · Cited by 102
Tümüklü, M. M., Etikán, Í., Kısacık, B., & Kayıkçıoğlu, M. (2007) · Echocardiography · doi:10.1111/j.1540-8175.2007.00484.x · Cited by 102
Borradaile, N. M., & Schaffer, J. E. (2005) · Current Hypertension Reports · doi:10.1007/s11906-005-0035-y · Cited by 99
Leichman, J. G., Wilson, E. B., Scarborough, T. K., Aguilar, D. A., Miller, C. C., Yu, S. C., Algahim, M. F., Reyes, M., Moody, F. G., & Taegtmeyer, H. (2008) · The American Journal of Medicine · doi:10.1016/j.amjmed.2008.06.033 · Cited by 100
Acar, G., Akçay, A., Sökmen, A., Özkaya, M., Güler, E., Sokmen, G., Kaya, H., Nacar, A. B., & Tuncer, C. (2009) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2009.03.028 · Cited by 97
Obesity: Effects on Cardiovascular Disease and its Diagnosis
Mathew, B., Francis, L., Kayalar, A. Ö., & Cone, J. (2008) · The Journal of the American Board of Family Medicine · doi:10.3122/jabfm.2008.06.080080 · Cited by 97
Orhan, A. L., Uslu, N., Dayı, Ş. Ü., Nurkalem, Z., Uzun, F., Erer, H. B., Hasdemir, H., Emre, A., Karakuş, G., Soran, O. Z., et al. (2010) · Echocardiography · doi:10.1111/j.1540-8175.2009.01024.x · Cited by 93
Altered mitochondrial metabolism in the insulin‐resistant heart
Makrecka‐Kuka, M., Liepinsh, E., Murray, A. J., Lemieux, H., Dambrova, M., Tepp, K., Puurand, M., Käämbre, T., Han, W. H., de Goede, P., et al. (2019) · Acta Physiologica · doi:10.1111/apha.13430 · Cited by 93
Willens, H. J., Chakko, S. C., Byers, P. M., Chirinos, J. A., Labrador, E., Castrillon, J. C., & Lowery, M. H. (2005) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2005.02.029 · Cited by 92
Adrenergic receptors and metabolism: role in development of cardiovascular disease
Ciccarelli, M., Santulli, G., Pascale, V., Trimarco, B., & Iaccarino, G. (2013) · Frontiers in Physiology · doi:10.3389/fphys.2013.00265 · Cited by 89
New developments in the pathogenesis of obesity-induced hypertension
Kotsis, V., Nilsson, P. M., Grassi, G. M., Mancia, G., Redón, J., Luft, F., Schmieder, R. E., Engeli, S., Stabouli, S., Antza, C., et al. (2015) · Journal of Hypertension · doi:10.1097/hjh.0000000000000645 · Cited by 91
Retained Metabolic Flexibility of the Failing Human Heart
Watson, W. D., Green, P. G., Lewis, A., Arvidsson, P. M., Maria, G. L. D., Arheden, H., Heiberg, E., Clarke, W. T., Rodgers, C. T., Valkovič, L., et al. (2023) · Circulation · doi:10.1161/circulationaha.122.062166 · Cited by 88
Obesity Cardiomyopathy: Is It a Reality? An Ultrasonic Tissue Characterization Study
Bello, V. D., Santini, F., Cori, A. D., Pucci, A. B. F., Palagi, C., Donne, M. G. D., Fierabracci, P., Marsili, A., Talini, E., Giannetti, M., et al. (2006) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2006.03.033 · Cited by 87
Dinh, W., Lankisch, M., Nickl, W., Scheyer, D., Scheffold, T., Kramer, F., Krahn, T., Klein, R. M., Barroso, M. C., & Füth, R. (2010) · Cardiovascular Diabetology · doi:10.1186/1475-2840-9-63 · Cited by 87
Comparative Impact of Morbid Obesity vs Heart Failure on Cardiorespiratory Fitness
Gallagher, M. J., Franklin, B. A., Ehrman, J. K., Keteyian, S. J., Brawner, C. A., deJong, A., & McCullough, P. A. (2005) · CHEST Journal · doi:10.1378/chest.127.6.2197 · Cited by 82
Toit, E. F. D., Nabben, M., & Lochner, A. (2005) · Basic Research in Cardiology · doi:10.1007/s00395-005-0528-5 · Cited by 80
Sex differences in myocardial oxygen and glucose metabolism
Peterson, L. R., Soto, P. F., Herrero, P., Schechtman, K. B., Dence, C. S., & Gropler, R. J. (2007) · Journal of Nuclear Cardiology · doi:10.1016/j.nuclcard.2007.03.001 · Cited by 80
Self-citationLin, C. H., Kurup, S., Herrero, P., Schechtman, K. B., Eagon, J. C., Klein, S., Dávila‐Román, V. G., Stein, R. I., Dorn, G. W., Gropler, R. J., et al. (2011) · Obesity · doi:10.1038/oby.2011.186 · Cited by 80
Self-citationEffects of weight loss on myocardial energetics and diastolic function in obesity
Rider, O. J., Francis, J. M., Tyler, D. J., Byrne, J. P., Clarke, K., & Neubauer, S. (2012) · International journal of cardiac imaging · doi:10.1007/s10554-012-0174-6 · Cited by 83
Fatty Acids and Insulin Modulate Myocardial Substrate Metabolism in Humans With Type 1 Diabetes
Peterson, L. R., Herrero, P., McGill, J. B., Schechtman, K. B., Kisrieva-Ware, Z., Lesniak, D., & Gropler, R. J. (2007) · Diabetes · doi:10.2337/db07-1199 · Cited by 79
Self-citationBostick, B., Habibi, J., DeMarco, V. G., Jia, G., Domeier, T. L., Lambert, M. D., Aroor, A. R., Nistala, R., Bender, S. B., Garro, M., et al. (2015) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00898.2014 · Cited by 79
Peterson, L. R., Saeed, I. M., McGill, J. B., Herrero, P., Schechtman, K. B., Gunawardena, R., Recklein, C. L., Coggan, A. R., DeMoss, A. J., Dence, C. S., et al. (2011) · Obesity · doi:10.1038/oby.2011.208 · Cited by 77
Self-citationRayner, J. J., Banerjee, R., Holloway, C. J., Lewis, A., Peterzan, M. A., Francis, J. M., Neubauer, S., & Rider, O. J. (2017) · International Journal of Obesity · doi:10.1038/ijo.2017.239 · Cited by 78
Heart of the matter: Coronary dysfunction in metabolic syndrome
Berwick, Z. C., Dick, G. M., & Tune, J. D. (2011) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2011.06.025 · Cited by 78
Myocardial substrate metabolism in obesity
Rider, O. J., Cox, P., Tyler, D. J., Clarke, K., & Neubauer, S. (2012) · International Journal of Obesity · doi:10.1038/ijo.2012.170 · Cited by 76
Haufe, S., Utz, W., Engeli, S., Kast, P., Böhnke, J., Pofahl, M., Traber, J., Haas, V., Hermsdorf, M., Mähler, A., et al. (2012) · Hypertension · doi:10.1161/hypertensionaha.111.178616 · Cited by 73
Dalen, H., Thorstensen, A., Romundstad, P., Aase, S. A., Støylen, A., & VATTEN, L. J. (2011) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2010.12.010 · Cited by 73
Kang, S., Fan, H., Li, J., Fan, L., Miao, A., Bao, Y., Wu, L., Zhu, Y., Dai-fu, Z., & Liu, Z. (2010) · European Heart Journal · doi:10.1093/eurheartj/ehq296 · Cited by 73
Mundy, A. L., Haas, E., Bhattacharya, I., Widmer, C. C., Kretz, M., Hofmann‐Lehmann, R., Minotti, R., & Barton, M. (2006) · Cardiovascular Research · doi:10.1016/j.cardiores.2006.11.019 · Cited by 75
Russo, C. A., Sera, F., Jin, Z., Palmieri, V., Homma, S., Rundek, T., Elkind, M. S. V., Sacco, R. L., & Tullio, M. R. D. (2016) · European Journal of Heart Failure · doi:10.1002/ejhf.521 · Cited by 70
Metadata
- Authors
- Peterson, L. R., Waggoner, A. D., Schechtman, K. B., Meyer, T., Gropler, R. J., Barzilai, B., & Dávila-Román, V. G.
- Affiliations
- Washington University in St. Louis (US)
- Corresponding author
- Peterson, Linda R
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 2004-04
- Volume
- 43
- Issue
- 8
- Pages
- 1399-1404
- ISSN
- 0735-1097 (ISSN-L)
- OpenAlex
- W2126975783
- Cited by
- 449
- References
- 28
- Citations by year
- 2026: 4 · 2025: 8 · 2024: 7 · 2023: 13 · 2022: 16 · 2021: 14 · 2020: 15 · 2019: 13 · 2018: 15 · 2017: 22 · 2016: 28 · 2015: 21 · 2014: 30 · 2013: 25 · 2012: 25
- FWCI
- 17.21
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of the American College of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Aging (R01 AG 15466, R01AG015466)
- National Heart, Lung, and Blood Institute (P01-HL13581, R01 HL 58878, R01HL058878, R01HL071782, K24 HL67002, R01HL71782, K24HL067002)
- National Center for Research Resources (M01-RR00036, M01RR000036)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (5K12HD145902)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Disease and Adiposity
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Effects of Exercise
- Keywords
- obesity, left ventricular structure, left ventricular function, young women, body mass index, concentric remodeling, left ventricular hypertrophy, systolic dysfunction, diastolic dysfunction, myocardial velocity, heart failure risk
- MeSH terms
- Adult, Diastole, Echocardiography, Female, Heart Ventricles, Humans, Obesity, Body Mass Index, Multivariate Analysis, Ventricular Function, Ventricular Dysfunction, Left, Ventricular Remodeling
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
