Primary Prevention of Cardiovascular Disease in Diabetes Mellitus
Open accessAbstract
Type 2 diabetes mellitus (T2D) is a major risk factor for cardiovascular disease (CVD), the most common cause of death in T2D. Yet, <50% of U.S. adults with T2D meet recommended guidelines for CVD prevention. The burden of T2D is increasing: by 2050, approximately 1 in 3 U.S. individuals may have T2D, and patients with T2D will comprise an increasingly large proportion of the CVD population. The authors believe it is imperative that we expand the use of therapies proven to reduce CVD risk in patients with T2D. The authors summarize evidence and guidelines for lifestyle (exercise, nutrition, and weight management) and CVD risk factor (blood pressure, cholesterol and blood lipids, glycemic control, and the use of aspirin) management for the prevention of CVD among patients with T2D. The authors believe appropriate lifestyle and CVD risk factor management has the potential to significantly reduce the burden of CVD among patients with T2D.
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Support for lifestyle and health behavior management in type 2 diabetes and stable coronary disease has been extrapolated from primary prevention trials and from type 2 diabetes subgroups in secondary prevention coronary studies.
“Instead, evidence to support lifestyle and health behavior management for T2DM and stable CAD has been extrapolated from primary prevention trials and from subgroups of participants with T2DM from studies focusing on the secondary prevention of CAD.63,136”
From Clinical management of stable coronary artery disease in patients with type 2 diabetes mellitus: a scientific statement from the American Heart Association (2020) · cites this paper as [136]
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- Authors
- Newman, J. D., Schwartzbard, A. Z., Weintraub, H. S., Goldberg, I. J., & Berger, J. S.
- Affiliations
- NYU Langone Health (US)
- Corresponding author
- Newman, Jonathan D.
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 2017-08
- Volume
- 70
- Issue
- 7
- Pages
- 883-893
- ISSN
- 0735-1097 (ISSN-L)
- PMC
- PMC5656394
- OpenAlex
- W2744536672
- Cited by
- 205
- References
- 89
- Citations by year
- 2026: 10 · 2025: 13 · 2024: 28 · 2023: 22 · 2022: 57 · 2021: 18 · 2020: 21 · 2019: 14 · 2018: 20 · 2017: 2
- FWCI
- 2.27
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of the American College of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- American Heart Association (15MCPRP24480132)
- Amgen
- AstraZeneca
- Sanofi
- Gilead Sciences
- Amarin Corporation
- National Institutes of Health (HL114978)
- National Heart, Lung, and Blood Institute (P01HL092969, K23HL125991, HL-114978, R01HL114978)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health Promotion and Cardiovascular Prevention
- Keywords
- type 2 diabetes, cardiovascular disease prevention, primary prevention, lifestyle modification, physical activity, nutrition, weight management, blood pressure control, glycemic control, aspirin therapy, cardiovascular risk factors
- MeSH terms
- Cardiovascular Diseases, Diabetes Mellitus, Type 2, Humans, Morbidity, Primary Prevention, Risk Factors, Global Health
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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