Cited by 1,202Artificial Intelligence in Healthcare and EducationArtificial Intelligence in HealthcareMachine Learning in Healthcare

Artificial intelligence in cardiology

Open access
Johnson, Kipp W., Torres Soto, Jessica, Glicksberg, Benjamin S., Shameer, Khader, Miotto, Riccardo, Ali, Mohsin, Ashley, Euan, Dudley, Joel T.·2018·Journal of the American College of Cardiology

Abstract

Artificial intelligence and machine learning are poised to influence nearly every aspect of the human condition, and cardiology is not an exception to this trend. This paper provides a guide for clinicians on relevant aspects of artificial intelligence and machine learning, reviews selected applications of these methods in cardiology to date, and identifies how cardiovascular medicine could incorporate artificial intelligence in the future. In particular, the paper first reviews predictive modeling concepts relevant to cardiology such as feature selection and frequent pitfalls such as improper dichotomization. Second, it discusses common algorithms used in supervised learning and reviews selected applications in cardiology and related disciplines. Third, it describes the advent of deep learning and related methods collectively called unsupervised learning, provides contextual examples both in general medicine and in cardiovascular medicine, and then explains how these methods could be applied to enable precision cardiology and improve patient outcomes.

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Research works printed but not linked: 4

  1. Konstam MA, Hill JA, Kovacs RJ, et al. The ac- ademic medical system: reinvention to survive the revolution in health care. J Am Coll Cardiol 2017; 69:1305-12.
  2. Steyerberg EW, Eijkemans MJ, Harrell FE Jr., Habbema JD. Prognostic modelling with logistic regression analysis: a comparison of selection and estimation methods in small data sets. Stat Med 2000;19:1059-79.
  3. Harrell FE. How To Do Bad Biomarker Research. Vanderbilt Center For Quantitative Sci- ences Workshop, Nashville, Tennessee, 2015.
  4. Narula S, Shameer K, Salem Omar AM, Dudley JT, Sengupta PP. Reply: Deep learning with unsupervised feature in echocardiographic imag- ing. J Am Coll Cardiol 2017;69:2101-2.

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Authors
Johnson, K. W., Torres Soto, J., Glicksberg, B. S., Shameer, K., Miotto, R., Ali, M., Ashley, E., & Dudley, J. T.
Affiliations
  • Mount Sinai Health System (US)
  • Northwell Health (US)
  • Stanford Medicine (US)
Corresponding author
Dudley, Joel T.
Venue
Journal of the American College of Cardiology
Publisher
Elsevier BV
Published
2018-06
Volume
71
Issue
23
Pages
2668-2679
ISSN
0735-1097 (ISSN-L)
OpenAlex
W2807593075
Cited by
1,202
References
50
Citations by year
2026: 134 · 2025: 176 · 2024: 180 · 2023: 147 · 2022: 198 · 2021: 156 · 2020: 111 · 2019: 83 · 2018: 16
FWCI
2.03
Type
journal article
Language
en
Open access
Locations
  • Journal of the American College of Cardiology (publishedVersion, cc-by)
  • PubMed (publishedVersion)
Funders
  • AstraZeneca
  • GlaxoSmithKline
  • F. Hoffmann-La Roche
  • LAM Therapeutics
  • National Institutes of Health (UL1TR000067)
  • National Cancer Institute (U54-CA189201-02, U54CA189201)
  • National Institute of Diabetes and Digestive and Kidney Diseases (R01DK098242)
  • National Center for Advancing Translational Sciences
  • Janssen Pharmaceuticals
  • Common Fund
Topics
  • Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
  • Health Sciences › Health Professions › Health Information Management › Artificial Intelligence in Healthcare
  • Physical Sciences › Computer Science › Artificial Intelligence › Machine Learning in Healthcare
Keywords
artificial intelligence in cardiology, machine learning, cardiology, predictive modeling, feature selection, dichotomization, supervised learning algorithms, deep learning, unsupervised learning, precision cardiology, clinical applications of AI
MeSH terms
Machine Learning, Algorithms, Artificial Intelligence, Cardiology, Cardiovascular Diseases, Humans

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