Cited by 529Mental Health Treatment and AccessAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesChronic Disease Management Strategies

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Depression-anxiety relationships with chronic physical conditions: results from the World Mental Health Surveys

Scott, K.M., Bruffaerts, R., Tsang, A., Ormel, J., Alonso, J., Angermeyer, M.C., Benjet, C., Bromet, E., de Girolamo, G., de Graaf, R., Gasquet, I., Gureje, O., Haro, J.M., He, Y., Kessler, R.C., Levinson, D., Mneimneh, Z.N., Oakley Browne, M.A., Posada-Villa, J., Stein, D.J., Takeshima, T., Von Korff, M.·2007·Journal of Affective Disorders

DOI 10.1016/j.jad.2007.01.015

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Abstract

Background Prior research on the association between affective disorders and physical conditions has been carried out in developed countries, usually in clinical populations, on a limited range of mental disorders and physical conditions, and has seldom taken into account the comorbidity between depressive and anxiety disorders.Methods Eighteen general population surveys were carried out among adults in 17 countries as part of the World Mental Health Surveys initiative (N=42, 249). DSM-IV depressive and anxiety disorders were assessed using face-to-face interviews with the Composite International Diagnostic Interview (CIDI 3.0). Chronic physical conditions were ascertained via a standard checklist. The relationship between mental disorders and physical conditions was assessed by considering depressive and anxiety disorders independently (depression without anxiety; anxiety without depression) and conjointly (depression plus anxiety).Results All physical conditions were significantly associated with depressive and/or anxiety disorders but there was variation in the strength of association (ORs 1.2-4.5). Non-comorbid depressive and anxiety disorders were associated in equal degree with physical conditions. Comorbid depressive-anxiety disorder was more strongly associated with several physical conditions than were single mental disorders.Limitations Physical conditions were ascertained via self report, though for a number of conditions this was self-report of diagnosis by a physician.Conclusions Given the prevalence and clinical consequences of the co-occurrence of mental and physical disorders, attention to their comorbidity should remain a clinical and research priority.

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Authors: Scott, K. M., Bruffaerts, R., Tsang, A., Ormel, J., Alonso, J., Angermeyer, M. C., Benjet, C., Bromet, E., de Girolamo, G., de Graaf, R., Gasquet, I., Gureje, O., Haro, J. M., He, Y., Kessler, R. C., Levinson, D., Mneimneh, Z. N., Oakley Browne, M. A., Posada-Villa, J., Stein, D. J., Takeshima, T., & Von Korff, M.
Affiliations: Victoria University of Wellington (NZ)
Universitair Ziekenhuis Leuven (BE)
Chinese University of Hong Kong (HK)
University Medical Center Groningen (NL)
Leipzig University (DE)
State University of New York (US)
Inserm (FR)
University College Hospital, Ibadan (NG)
Shanghai Mental Health Center (CN)
Harvard University (US)
Israel Ministry of Health (IL)
Institute for Development, Research, Advocacy and Applied Care (LB)
Groote Schuur Hospital (ZA)
Corresponding author: Scott, K.M.
ORCID: Bruffaerts, R.
Ormel, J.
Alonso, J.
Benjet, C.
Bromet, E.
Gureje, O.
Haro, J.M.
He, Y.
Kessler, R.C.
Stein, D.J.
Takeshima, T.
Venue: Journal of Affective Disorders
Publisher: Elsevier BV
Published: 2007-11
Volume: 103
Issue: 1-3
Pages: 113-120
ISSN: 0165-0327 (ISSN-L)
DOI: 10.1016/j.jad.2007.01.015
OpenAlex: W2067984600
Cited by: 529
References: 41
Citations by year: 2026: 12 · 2025: 26 · 2024: 21 · 2023: 25 · 2022: 42 · 2021: 37 · 2020: 29 · 2019: 30 · 2018: 30 · 2017: 30 · 2016: 39 · 2015: 27 · 2014: 36 · 2013: 30 · 2012: 19
FWCI: 32.61
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Journal of Affective Disorders (publishedVersion)
PubMed (publishedVersion)
University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion)
Funders: World Health Organization
National Institutes of Health (5r13mh066849-04, 5r01mh069864-04, 5r01mh070884-05)
National Institute of Mental Health (R13-MH-066849, R0 1-MH61905, R01‐MH070884, U01-MH-60220, R01MH061905, R01MH059575, U01MH060220, R01‐MH069864)
National Institute on Drug Abuse (R01DA016558)
Fogarty International Center (R01-TW006481)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Health Sciences › Medicine › Epidemiology › Chronic Disease Management Strategies
Keywords: depression, anxiety disorders, chronic physical illness, comorbidities, World Mental Health Surveys, general population
MeSH terms: Adult, Aged, Anxiety Disorders, Chronic Disease, Cross-Sectional Studies, Cross-Cultural Comparison, Major Depressive Disorder, Depressive Disorder, Major, Female, Health Surveys, Humans, Male, Middle Aged, Sick Role, Comorbidity, Dysthymic Disorder

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Depression-anxiety relationships with chronic physical conditions: results from the World Mental Health Surveys

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