Lifetime costs of perinatal anxiety and depression
Open accessAbstract
Background Anxiety and depression are common among women during pregnancy and the year after birth. The consequences, both for the women themselves and for their children, can be considerable and last for many years. This study focuses on the economic consequences, aiming to estimate the total costs and health-related quality of life losses over the lifetime of mothers and their children.Method A pathway or decision modelling approach was employed, based on data from previous studies. Systematic and pragmatic literature reviews were conducted to identify evidence of impacts of perinatal anxiety and depression on mothers and their children.Results The present value of total lifetime costs of perinatal depression (anxiety) was £75,728 (£34,811) per woman with condition. If prevalence estimates were applied the respective cost of perinatal anxiety and depression combined was about £8500 per woman giving birth; for the United Kingdom, the aggregated costs were £6.6 billion. The majority of the costs related to adverse impacts on children and almost a fifth were borne by the public sector.Limitations The method was exploratory in nature, based on a diverse range of literature and encountered important data gaps.Conclusions Findings suggest the need to allocate more resources to support women with perinatal mental illness. More research is required to understand the type of interventions that can reduce long-term negative effects for both mothers and offspring.
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Peripartum depression is associated with poor health-related quality of life and, in extreme cases, loss of life through suicide.
“For mothers, PPD is associated with poor health-related quality of life and in extreme cases loss of life through suicide.11”
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- Authors
- Bauer, A., Knapp, M., & Parsonage, M.
- Affiliations
- London School of Economics and Political Science (GB)
- Centre for Mental Health (GB)
- Corresponding author
- Bauer, Annette
- Venue
- Journal of Affective Disorders
- Publisher
- Elsevier BV
- Published
- 2016-03
- Volume
- 192
- Pages
- 83-90
- ISSN
- 0165-0327 (ISSN-L)
- OpenAlex
- W2216037864
- Cited by
- 382
- References
- 63
- Citations by year
- 2026: 38 · 2025: 57 · 2024: 60 · 2023: 72 · 2022: 40 · 2021: 38 · 2020: 35 · 2019: 17 · 2018: 12 · 2017: 8 · 2016: 4
- FWCI
- 8.56
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Affective Disorders (publishedVersion)
- PubMed (publishedVersion)
- London School of Economics and Political Science Research Online (London School of Economics and Political Science) (submittedVersion)
- London School of Economics and Political Science Theses Online (London School of Economics and Political Science) (submittedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Keywords
- perinatal anxiety, perinatal depression, lifetime costs, health-related quality of life, maternal mental health, child outcomes, economic burden, public sector costs, decision models, perinatal mental disorders
- MeSH terms
- Adult, Anxiety, Costs and Cost Analysis, Depression, Female, United Kingdom, Humans, Pregnancy, Pregnancy Complications, Quality of Life, Prevalence, Perinatal Care, Young Adult
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