Treatment credibility, expectancy, and preference: Prediction of treatment engagement and outcome in a randomized clinical trial of hatha yoga vs. health education as adjunct treatments for depression
Open accessAbstract
Background Hatha yoga may be helpful for alleviating depression symptoms. The purpose of this analysis is to determine whether treatment program preference, credibility, or expectancy predict engagement in depression interventions (yoga or a control class) or depression symptom severity over time.Methods This is a secondary analysis of a randomized controlled trial (RCT) of hatha yoga vs. a health education control group for treatment of depression. Depressed participants (n = 122) attended up to 20 classes over a period of 10 weeks, and then completed additional assessments after 3 and 6 months. We assessed treatment preference prior to randomization, and treatment credibility and expectancy after participants attended their first class. Treatment "concordance" indicated that treatment preference matched assigned treatment.Results Treatment credibility, expectancy, and concordance were not associated with treatment engagement. Treatment expectancy moderated the association between treatment group and depression. Depression severity over time differed by expectancy level for the yoga group but not for the health education group. Controlling for baseline depression, participants in the yoga group with an average or high expectancy for improvement showed lower depression symptoms across the acute intervention and follow-up period than those with a low expectancy for improvement. There was a trend for a similar pattern for credibility. Concordance was not associated with treatment outcome.Limitations This is a secondary, post-hoc analysis and should be considered hypothesis-generating.Conclusions Results suggest that expectancy improves the likelihood of success only for a intervention thought to actively target depression (yoga) and not a control intervention.
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Uebelacker (2018) presents study data with a line graph rather than exact numbers, and it was hard to abstract.
“Uebelacker (2018) presents study data with a line graph rather than exact numbers, and we find it hard to abstract it [61]”
From The effectiveness of mindfulness yoga on patients with major depressive disorder: a systematic review and meta-analysis of randomized controlled trials (2023) · cites this paper as [61]
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- Authors
- Uebelacker, L. A., Weinstock, L. M., Battle, C. L., Abrantes, A. M., & Miller, I. W.
- Affiliations
- Brown University (US)
- Corresponding author
- Uebelacker, Lisa A.
- Venue
- Journal of Affective Disorders
- Publisher
- Elsevier BV
- Published
- 2018-10
- Volume
- 238
- Pages
- 111-117
- ISSN
- 0165-0327 (ISSN-L)
- PMC
- PMC6901089
- OpenAlex
- W2806472702
- Cited by
- 25
- References
- 23
- Citations by year
- 2026: 3 · 2025: 6 · 2024: 6 · 2023: 1 · 2022: 4 · 2021: 3 · 2020: 1 · 2019: 1
- FWCI
- 1.47
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Affective Disorders (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (R01NR012005)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Life Sciences › Neuroscience › Cognitive Neuroscience › Pain Management and Placebo Effect
- Keywords
- hatha yoga, depression, treatment credibility, treatment expectancy, treatment preferences, treatment engagement, treatment concordance, health education, depression severity, treatment outcome prediction
- MeSH terms
- Adult, Depression, Female, Humans, Male, Middle Aged, Patient Education as Topic, Patient Participation, Yoga, Treatment Outcome, Patient Preference
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