Indoor environmental interventions for furry pet allergens, pest allergens, and mold: looking to the future
Open accessAbstract
Over the last 2 to 3 decades, significant advances have been made in understanding the role that indoor allergen exposures play with regard to respiratory health. Multiple studies have confirmed that sensitization and exposure to indoor allergens can be a risk factor for asthma morbidity. Environmental interventions targeting key indoor allergens have been evaluated with the aims of examining their causal effects on asthma-related outcomes and identifying clinically efficacious interventions to incorporate into treatment recommendations. Historically, it appeared that the most successful intervention, as performed in the Inner-City Asthma Study, was individually tailored, targeting multiple allergens in a predominantly low-income, minority, and urban pediatric population. Recent studies suggest that single-allergen interventions may be efficacious when targeting the most clinically relevant allergen for a population. In this article, we review recent literature on home environmental interventions and their effects on specific indoor allergen levels and asthma-related outcomes.
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About 95-100% of inner-city households and schools have measurable levels of mouse allergen.
“Approximately 95–100% of inner-city households and schools contain measurable levels of this allergen (34,38,39,40,41,42).”
From Indoor Allergen Interventions in Homes and Schools for Managing Asthma (2025) · cites this paper as [34]
The Mouse allergen section says mouse allergen in settled dust is “virtually ubiquitous” in some low-income urban communities, which supports the claim's general point about homes. It does not give a 95–100% figure or establish that prevalence for inner-city schools, and it limits the observation to some communities. (LLM, conf=0.85)
Experimental — accuracy not yet measuredCockroach allergens such as Bla g 1, Bla g 2, and Per a 1 are found in cockroach saliva, debris, secretions, and feces.
“Cockroach allergens, including Bla g 1 and Bla g 2 from the German cockroach and Per a 1 from the American cockroach, are present in cockroach saliva, debris, secretions, and feces (33,34,35).”
From Indoor Allergen Interventions in Homes and Schools for Managing Asthma (2025) · cites this paper as [34]
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“However, recent studies in Baltimore and New York City have suggested that cockroach allergen may be less clinically important than mouse allergen in these populations.(2,38) It is important to note, however, that the lack of population-level clinical effect of cockroach allergen does not mean that an individual in th…”
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Home Assessment and Remediation
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Flagged first, then by citations
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Aeroallergen Exposure and Spread in the Modern Era.
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Indoor Allergen Interventions in Homes and Schools for Managing Asthma
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SENSIBILIZAÇÃO DA BLOMIA TROPICALIS EM PACIENTES ASMÁSTICOS EM SÃO LUÍS E REGIÕES METROPOLITANA
de Brito, P. O. L., Duarte, T. D., Lima, J. L. D. C., Pereira, C. Z. K. D. P. C., Azevedo, C. R., Pereira, M. G., & Falcai, Â. (2019) · Revista Ceuma Perspectivas · doi:10.24863/rccp.v30i2.149
Allergie au chat chez l’enfant : du diagnostic à la prise en charge
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Edwards-Salmon, S. E. (2025) · Springer eBooks · doi:10.1007/978-3-031-93455-1_35
- Authors
- Ahluwalia, S. K., & Matsui, E. C.
- Affiliations
- Uniformed Services University of the Health Sciences (US)
- Johns Hopkins University (US)
- Corresponding author
- Matsui, Elizabeth C.
- ORCID
- Matsui, Elizabeth C.
- Venue
- The Journal of Allergy and Clinical Immunology: In Practice
- Publisher
- Elsevier BV
- Published
- 2018-01
- Volume
- 6
- Issue
- 1
- Pages
- 9-19
- ISSN
- 2213-2198 (ISSN-L)
- PMC
- PMC5763515
- OpenAlex
- W2781960999
- Cited by
- 62
- References
- 99
- Citations by year
- 2025: 10 · 2024: 2 · 2023: 9 · 2022: 11 · 2021: 6 · 2020: 7 · 2019: 11 · 2018: 6
- FWCI
- 0.79
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- The Journal of Allergy and Clinical Immunology In Practice (acceptedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Allergy and Infectious Diseases (K24AI114769, U01AI083238)
- National Institute of Environmental Health Sciences (R01ES023447, R01ES026170)
- Topics
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Indoor Air Quality and Microbial Exposure
- Health Sciences › Medicine › Physiology › Asthma and respiratory diseases
- Health Sciences › Medicine › Immunology and Allergy › Allergic Rhinitis and Sensitization
- Keywords
- indoor allergens, house dust mites, molds, asthma, environmental interventions, allergen reduction, asthma morbidity, childhood asthma, allergen sensitization
- MeSH terms
- Animal Fur, Allergens, Animals, Asthma, Child, Cockroaches, Environmental Exposure, Fungi, Humans, Hypersensitivity, Risk Factors, Urban Population, Treatment Outcome, Air Pollution, Indoor, Pets
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