The DOI matches its Crossref record; 55 of the 56 references it cites were found in a registry or an index.
Affective outcomes of virtual reality exposure therapy for anxiety and specific phobias: A meta-analysis
Abstract
Virtual reality exposure therapy (VRET) is an increasingly common treatment for anxiety and specific phobias. Lacking is a quantitative meta-analysis that enhances understanding of the variability and clinical significance of anxiety reduction outcomes after VRET. Searches of electronic databases yielded 52 studies, and of these, 21 studies (300 subjects) met inclusion criteria. Although meta-analysis revealed large declines in anxiety symptoms following VRET, moderator analyses were limited due to inconsistent reporting in the VRET literature. This highlights the need for future research studies that report uniform and detailed information regarding presence, immersion, anxiety and/or phobia duration, and demographics.
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“The heterogenicity of designs leads to inconsistent quantitative data gathering, making it impossible to achieve higher hierarchical evidence-based conclusions through systematic reviews and meta-analysis [135].”
From SAFEvR MentalVeRse.app: Development of a Free Immersive Virtual Reality Exposure Therapy for Acrophobia and Claustrophobia (2024) · cites this paper as [135]
In the citing paper
“it has shown its efficacy for treating specific phobias (including FP) in several studies (Botella et al., 2017; Parsons and Rizzo, 2008)”
From An Internet-based treatment for Flying Phobia using 360° images: Study protocol for a feasibility pilot study (2021) · cites this paper as Parsons and Rizzo, 2008
In the citing paper
“The aim of in vivo exposure treatment is to promote emotional regulation using systematic and controlled therapeutic exposure to traumatic stimuli [191].”
From Impact of Media-Induced Uncertainty on Mental Health: Narrative-Based Perspective. (2025) · cites this paper as [191]
In the citing paper
“This is especially impressive given that both groups received an active psychotherapy with documented efficacy for the treatment of terrorist-related chronic PTSD (Difede et al, 2007; Parsons and Rizzo, 2008).”
From D-cycloserine augmentation of exposure therapy for post-traumatic stress disorder: a pilot randomized clinical trial (2014) · cites this paper as Parsons and Rizzo, 2008
In the citing paper
“As in previous meta-analyses [9,10], the results further confirm VRET's potential in treating these problems.”
From Recent Progress in Virtual Reality Exposure Therapy for Phobias: A Systematic Review (2017) · cites this paper as [9]
Citations
Cites
Statistical Power Analysis for the Behavioral Sciences
Muller, K. E., & Cohen, J. (1989) · Technometrics · doi:10.2307/1270020 · Cited by 99,603
Statistical power analysis for the behavioral sciences
Cohen, J. (1990) · Computers Environment and Urban Systems · doi:10.1016/0198-9715(90)90050-4 · Cited by 65,417
Statistical Power Analysis for the Behavioral Sciences (2nd ed.).
Lachenbruch, P. A., & Cohen, J. (1989) · Journal of the American Statistical Association · doi:10.2307/2290095 · Cited by 37,421
Wasserman, S. S., Hedges, L. V., & Olkin, I. (1988) · Journal of Educational Statistics · doi:10.2307/1164953 · Cited by 10,377
The file drawer problem and tolerance for null results.
Rosenthal, R. (1979) · Psychological Bulletin · doi:10.1037/0033-2909.86.3.638 · Cited by 9,068
Cohen, J. (1992) · Psychological Bulletin · doi:10.1037//0033-2909.112.1.155 · Cited by 8,771
Measuring Presence in Virtual Environments: A Presence Questionnaire
Witmer, B. G., & Singer, M. J. (1998) · Presence: Teleoperators and Virtual Environments · doi:10.1162/105474698565686 · Cited by 6,371
Emotional processing of fear: Exposure to corrective information.
Foa, E. B., & Kozak, M. J. (1986) · Psychological Bulletin · doi:10.1037/0033-2909.99.1.20 · Cited by 5,396
The combination of estimates from different experiments
Cochran, W. G. (1954) · Biometrics · doi:10.2307/3001666 · Cited by 5,380
Statistical Methods for Meta-Analysis.
Freeman, P. R., Hedges, L. V., & Olkin, I. (1986) · Biometrics · doi:10.2307/2531069 · Cited by 4,840
Handbook of Psychotherapy and Behavior Change
Garfield, S. L., Bergin, A. E., & Dryden, W. (1987) · Journal of Cognitive Psychotherapy · doi:10.1891/0889-8391.1.4.264a · Cited by 3,998
The Handbook of Research Synthesis.
Howel, D., Cooper, H., & Hedges, L. V. (1995) · Biometrics · doi:10.2307/2533295 · Cited by 3,657
Quantitative Synthesis in Systematic Reviews
Lau, J., Ioannidis, J. P. A., & Schmid, C. H. (1997) · Annals of Internal Medicine · doi:10.7326/0003-4819-127-9-199711010-00008 · Cited by 2,517 · cited 1×
“In general, p-values less than 0.01 for the Q-statistic are considered to indicate significant differences across studies ( Lau, Ioannidis, & Schmid, 1997 ).”
MethodInfluentialComorbidity of anxiety and unipolar mood disorders
Mineka, S., Watson, D., & Clark, L. A. (1998) · Annual Review of Psychology · doi:10.1146/annurev.psych.49.1.377 · Cited by 1,573
Emotion, plasticity, context, and regulation: Perspectives from affective neuroscience.
Davidson, R. J., Jackson, D. C., & Kalin, N. H. (2000) · Psychological Bulletin · doi:10.1037/0033-2909.126.6.890 · Cited by 1,322 · cited 1×
“Over-excitation and deprivation can influence the affective system and may induce changes in the emotional circuitry of the brain that can contribute to stress-related psychopathology ( Davidson, Jackson, & Kalin, 2000 ).”
BackgroundModulating emotional responses: effects of a neocortical network on the limbic system
Hariri, A. R., Bookheimer, S. Y., & Mazziotta, J. C. (2000) · NeuroReport · doi:10.1097/00001756-200001170-00009 · Cited by 1,277
The neuroanatomical and neurochemical basis of conditioned fear
Fendt, M., & Fanselow, M. S. (1999) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(99)00016-0 · Cited by 1,092
Effectiveness of computer-generated (virtual reality) graded exposure in the treatment of acrophobia
(1995) · American Journal of Psychiatry · doi:10.1176/ajp.152.4.626 · Cited by 694
Virtual Reality Exposure Therapy for Vietnam Veterans With Posttraumatic Stress Disorder
Rothbaum, B. O., Hodges, L. F., Ready, D. J., Graap, K. M., & Alarcón, R. D. (2001) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v62n0808 · Cited by 531
Heim, C., & Nemeroff, C. B. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00224-3 · Cited by 502
A controlled study of virtual reality exposure therapy for the fear of flying.
Rothbaum, B. O., Hodges, L., Smith, S., Lee, J. H., & Price, L. (2000) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.68.6.1020 · Cited by 501
How meta-analysis increases statistical power.
Cohn, L. D., & Becker, B. J. (2003) · Psychological Methods · doi:10.1037/1082-989x.8.3.243 · Cited by 500
Virtual reality exposure therapy of anxiety disorders: A review
Krijn, M., Emmelkamp, P. M. G., Olafsson, R. P., & Biemond, R. (2004) · Clinical Psychology Review · doi:10.1016/j.cpr.2004.04.001 · Cited by 492
Virtual reality in the treatment of spider phobia: a controlled study
Garcia-Palacios, A., Hoffman, H., Carlin, A., Furness, T. A., & Botella, C. (2002) · Behaviour Research and Therapy · doi:10.1016/s0005-7967(01)00068-7 · Cited by 490
Virtual reality treatment versus exposure in vivo: a comparative evaluation in acrophobia
Emmelkamp, P. M. G., Krijn, M., Hulsbosch, A. M., de Vries, S., Schuemie, M. J., & van der Mast, C. A. P. G. (2002) · Behaviour Research and Therapy · doi:10.1016/s0005-7967(01)00023-7 · Cited by 475
Klinger, E., Bouchard, S., Légeron, P., Roy, S., Lauer, F., Chemin, I., & Nugues, P. (2005) · CyberPsychology & Behavior · doi:10.1089/cpb.2005.8.76 · Cited by 327
Treatment of acrophobia in virtual reality: The role of immersion and presence
Krijn, M., Emmelkamp, P. M. G., Biemond, R., de Wilde de Ligny, C., Schuemie, M. J., & van der Mast, C. A. P. G. (2004) · Behaviour Research and Therapy · doi:10.1016/s0005-7967(03)00139-6 · Cited by 320 · cited 3×
“Additionally, virtual reality system characteristics may moderate the level of presence felt (Krijn et al., 2004a).”
BackgroundBrief Virtual Reality Therapy for Public Speaking Anxiety
Harris, S. R., Kemmerling, R. L., & North, M. M. (2002) · CyberPsychology & Behavior · doi:10.1089/109493102321018187 · Cited by 314
Exposure therapy for posttraumatic stress disorder
Rothbaum, B. O., & Schwartz, A. C. (2002) · American Journal of Psychotherapy · doi:10.1176/appi.psychotherapy.2002.56.1.59 · Cited by 313
Cognitive behavioral therapy for public-speaking anxiety using virtual reality for exposure
Anderson, P. L., Zimand, E., Hodges, L. F., & ROTHBAUM, B. O. (2005) · Depression and Anxiety · doi:10.1002/da.20090 · Cited by 289
Ogles, B. M., Lunnen, K. M., & Bonesteel, K. (2001) · Clinical Psychology Review · doi:10.1016/s0272-7358(99)00058-6 · Cited by 255
Virtual Reality Treatment in Acrophobia: A Comparison with Exposure in Vivo
Emmelkamp, P. M. G., Bruynzeel, M., Drost, L., & van der Mast, C. P. A. G. (2001) · CyberPsychology & Behavior · doi:10.1089/109493101300210222 · Cited by 241
Rothbaum, B. O., Anderson, P., Zimand, E., Hodges, L., Lang, D., & Wilson, J. (2006) · Behavior Therapy · doi:10.1016/j.beth.2005.04.004 · Cited by 240
Repeated exposure of flight phobics to flights in virtual reality
Mühlberger, A., Herrmann, M. J., Wiedemann, G., Ellgring, H., & Pauli, P. (2001) · Behaviour Research and Therapy · doi:10.1016/s0005-7967(00)00076-0 · Cited by 187
Effectiveness of virtual reality exposure in the treatment of arachnophobia using 3D games
Bouchard, S., Côté, S., St-Jacques, J., Robillard, G., & Renaud, P. (2006) · Technology and Health Care · doi:10.3233/thc-2006-14103 · Cited by 156
The Way in Which Intervention Studies Have "Personality" and Why It Is Important to Meta-Analysis
Lipsey, M. W., & Wilson, D. B. (2001) · Evaluation & the Health Professions · doi:10.1177/016327870102400302 · Cited by 152
Virtual reality exposure therapy for the treatment of fear of flying: A controlled investigation.
Maltby, N., Kirsch, I., Mayers, M., & Allen, G. J. (2002) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.70.5.1112 · Cited by 147
Vincelli, F., Anolli, L., Bouchard, S., Wiederhold, B. K., Zurloni, V., & Riva, G. (2003) · CyberPsychology & Behavior · doi:10.1089/109493103322011632 · Cited by 145
Interfaces that heal: coupling real and virtual objects to treat spider phobia
Hoffman, H. G., Garcia-Palacios, A., Carlin, A., Furness III, T. A., & Botella-Arbona, C. (2003) · International Journal of Human-Computer Interaction · doi:10.1207/s15327590ijhc1602_08 · Cited by 144
Advances in statistical methods for meta‐analysis
Hedges, L. V. (1984) · New Directions for Program Evaluation · doi:10.1002/ev.1376 · Cited by 142
Virtual reality for psychotherapy: Current reality and future possibilities.
Glanz, K., Rizzo, A., & Graap, K. M. (2003) · Psychotherapy · doi:10.1037/0033-3204.40.1-2.55 · Cited by 142
Self-citationEffectiveness of Virtual Environment Desensitization in the Treatment of Agoraphobia
North, M. M., North, S. M., & Coble, J. R. (1996) · PRESENCE Virtual and Augmented Reality · doi:10.1162/pres.1996.5.3.346 · Cited by 127
Virtual Reality and Psychotherapy
Botella, C., Soledad, Q., Baños, R., Perpiñá, C., García‐Palacios, A., & Giuseppe, R. (2004) · Studies in health technology and informatics · doi:10.3233/978-1-60750-943-1-37 · Cited by 121
Neuroanatomical aspects of cognitive-behavioural therapy response in obsessive-compulsive disorder
Schwartz, J. M. (1998) · The British Journal of Psychiatry · doi:10.1192/s0007125000297882 · Cited by 116
Lessons Learned From 600 Virtual Reality Sessions
Wiederhold, B. K., & Wiederhold, M. D. (2000) · CyberPsychology & Behavior · doi:10.1089/10949310050078841 · Cited by 111
Côté, S., & Bouchard, S. (2005) · Applied Psychophysiology and Biofeedback · doi:10.1007/s10484-005-6379-x · Cited by 109
Emmelkamp, P. M. G. (1986) · UvA-DARE (University of Amsterdam) · Cited by 106
Treating psychological and phsyical disorders with VR
Hodges, L. F., Anderson, P. L., Burdea, G., Hoffmann, H., & ROTHBAUM, B. O. (2001) · IEEE Computer Graphics and Applications · doi:10.1109/38.963458 · Cited by 105
Definition of a VR-Based Protocol to Treat Social Phobia
Roy, S., Klinger, É., Légeron, P., Lauer, F., Chemin, I., & Nugues, P. (2003) · CyberPsychology & Behavior · doi:10.1089/109493103322278808 · Cited by 97
Virtual reality exposure therapy for the treatment of fear of flying: A controlled investigation.
Maltby, N., Kirsch, I., Mayers, M., et al. (2002) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.70.5.1112 · Cited by 97
Wilhelm, F. H., Pfaltz, M. C., Gross, J. J., Mauss, I. B., Kim, S. I., & Wiederhold, B. K. (2005) · Applied Psychophysiology and Biofeedback · doi:10.1007/s10484-005-6383-1 · Cited by 81
Effects of Group Experiential Cognitive Therapy for the Treatment of Panic Disorder with Agoraphobia
Choi, Y.-H., Vincelli, F., Riva, G., Wiederhold, B. K., Lee, J.-H., & Park, K.-H. (2005) · CyberPsychology & Behavior · doi:10.1089/cpb.2005.8.387 · Cited by 74
Current status of virtual reality exposure therapy in anxiety disorders: editorial review.
Pull, C. B. (2005) · PubMed · Cited by 66
The Application of Virtual Reality to the Treatment of PTSD Following the WTC Attack
Difede, J., Cukor, J., Patt, I. S., Giosan, C., & Hoffman, H. G. (2006) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1364.052 · Cited by 57
Raedt, R. D. (2006) · Scandinavian Journal of Psychology · doi:10.1111/j.1467-9450.2006.00511.x · Cited by 32
Research works printed but not linked: 1
- 2005, Current Opinion in Psychiatry, 18, 7
Cited by
Sorted by citations
Virtual reality in neuroscience research and therapy
Bohil, C. J., Alicea, B., & Biocca, F. A. (2011) · Nature Reviews Neuroscience · doi:10.1038/nrn3122 · Cited by 1,108
Katzman, M. A., Bleau, P., Blier, P., Chokka, P., Kjernisted, K., Van Ameringen, M., & the Canadian Anxiety Guidelines Initiative Group on behalf of the Anxiety Disorders Association of Canada/Association Canadienne des troubles anxieux and McGill University (2014) · BMC Psychiatry · doi:10.1186/1471-244x-14-s1-s1 · Cited by 1,090
“Exposure-based treatments All specific phobias [57,311,312]”
BackgroundDiemer, J., Alpers, G. W., Peperkorn, H. M., Shiban, Y., & Mühlberger, A. (2015) · Frontiers in Psychology · doi:10.3389/fpsyg.2015.00026 · Cited by 959
Carl, E., Stein, A. T., Levihn-Coon, A., Pogue, J. R., Rothbaum, B., Emmelkamp, P., Asmundson, G. J. G., Carlbring, P., & Powers, M. B. (2019) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2018.08.003 · Cited by 889
The use of virtual reality technology in the treatment of anxiety and other psychiatric disorders
Maples-Keller, J. L., Bunnell, B. E., Kim, S.-J., & Rothbaum, B. O. (2017) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000138 · Cited by 862
“…treatment research has been conducted for anxiety disorders, and broadly, results suggest the VRE is related to large declines in anxiety symptoms, 12 demonstrates similar efficacy compared to traditional exposure interventions, has a powerful real-life impact, and demonstrates good stability of…”
Result
Metadata
- Authors
- Parsons, T. D., & Rizzo, A. A.
- Affiliations
- University of Southern California (US)
- Corresponding author
- Parsons, Thomas D.
- Venue
- Journal of Behavior Therapy and Experimental Psychiatry
- Publisher
- Elsevier BV
- Published
- 2008-09
- Volume
- 39
- Issue
- 3
- Pages
- 250-261
- ISSN
- 0005-7916 (ISSN-L)
- OpenAlex
- W2080509533
- Cited by
- 994
- References
- 56
- Citations by year
- 2026: 38 · 2025: 56 · 2024: 63 · 2023: 51 · 2022: 59 · 2021: 69 · 2020: 83 · 2019: 101 · 2018: 84 · 2017: 53 · 2016: 50 · 2015: 47 · 2014: 43 · 2013: 42 · 2012: 34
- FWCI
- 3.16
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Behavior Therapy and Experimental Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Computer Science › Human-Computer Interaction › Virtual Reality Applications and Impacts
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Keywords
- virtual reality exposure therapy, anxiety disorders, specific phobia, anxiety reduction, treatment outcomes, presence, immersion
- MeSH terms
- Anxiety Disorders, Forecasting, Humans, Implosive Therapy, Phobic Disorders, Research Design, Stress Disorders, Post-Traumatic, User-Computer Interface, Treatment Outcome, Sample Size
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