Gamma-aminobutyric acid as a bioactive compound in foods: A review

Diana, Marina; Quílez, Joan; Rafecas, Magdalena

doi:10.1016/j.jff.2014.07.004

Cited by 473GABA and Rice ResearchProbiotics and Fermented FoodsProtein Hydrolysis and Bioactive Peptides

Gamma-aminobutyric acid as a bioactive compound in foods: A review

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Diana, Marina, Quílez, Joan, Rafecas, Magdalena·2014·Journal of Functional Foods

DOI 10.1016/j.jff.2014.07.004

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GABA has physiological functions such as blood pressure regulation, diuretic effects, and insulin secretion, and may contribute to prevention of diabetes.
“GABA has several important physiological functions, such as blood pressure regulation, diuretic effects, and insulin secretion; hence, it may contribute to the prevention of diabetes [269,275].”
From Lactic Acid Bacteria in Raw-Milk Cheeses: From Starter Cultures to Probiotic Functions (2022) · cites this paper as [269]
GABA is the major inhibitory neurotransmitter of the central nervous system.
“GABA is the major inhibitory neurotransmitter of the central nervous system [269,272,273,274].”
From Lactic Acid Bacteria in Raw-Milk Cheeses: From Starter Cultures to Probiotic Functions (2022) · cites this paper as [269]

γ-Aminobutyric acid production by culturable bacteria from the human intestine
Barrett, E., Ross, R. P., O'Toole, P. W., Fitzgerald, G. F., & Stanton, C. (2012) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2012.05344.x · Cited by 1,156 · see citing works
Bioactive peptides from marine processing waste and shellfish: A review
Harnedy, P. A., & Fitzgerald, R. J. (2011) · Journal of Functional Foods · doi:10.1016/j.jff.2011.09.001 · Cited by 606 · see citing works
GABA and Its Agonists Improved Visual Cortical Function in Senescent Monkeys
Leventhal, A. G., Wang, Y., Pu, M., Zhou, Y., & Ma, Y. (2003) · Science · doi:10.1126/science.1082874 · Cited by 557 · see citing works
Glutamate and GABA systems as targets for novel antidepressant and mood-stabilizing treatments
Krystal, J. H., Sanacora, G., Blumberg, H., Anand, A., Charney, D. S., Marek, G., Epperson, C. N., Goddard, A., & Mason, G. F. (2002) · Molecular Psychiatry · doi:10.1038/sj.mp.4001021 · Cited by 553 · see citing works
Blood-pressure-lowering effect of a novel fermented milk containing γ-aminobutyric acid (GABA) in mild hypertensives
Inoue, K., Shirai, T., Ochiai, H., Kasao, M., Hayakawa, K., Kimura, M., & Sansawa, H. (2003) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1601555 · Cited by 546 · see citing works
GABA, ?-hydroxybutyric acid, and neurological disease
Wong, C. G. T., Bottiglieri, T., & Snead, O. C. (2003) · Annals of Neurology · doi:10.1002/ana.10696 · Cited by 489 · see citing works
Synthesis of γ-Aminobutyric Acid by Lactic Acid Bacteria Isolated from a Variety of Italian Cheeses
Siragusa, S., De Angelis, M., Di Cagno, R., Rizzello, C. G., Coda, R., & Gobbetti, M. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.01064-07 · Cited by 438 · see citing works
Relaxation and immunity enhancement effects of γ‐Aminobutyric acid (GABA) administration in humans
Abdou, A. M., Higashiguchi, S., Horie, K., Kim, M., Hatta, H., & Yokogoshi, H. (2006) · BioFactors · doi:10.1002/biof.5520260305 · Cited by 407 · see citing works
Production of γ-aminobutyric acid (GABA) by Lactobacillus paracasei isolated from traditional fermented foods
Komatsuzaki, N., Shima, J., Kawamoto, S., Momose, H., & Kimura, T. (2005) · Food Microbiology · doi:10.1016/j.fm.2005.01.002 · Cited by 391 · see citing works
Lactic acid bacterial cell factories for gamma-aminobutyric acid
Li, H., & Cao, Y. (2010) · Amino Acids · doi:10.1007/s00726-010-0582-7 · Cited by 345 · see citing works
Yoga Asana Sessions Increase Brain GABA Levels: A Pilot Study
Streeter, C. C., Jensen, J. E., Perlmutter, R., Cabral, H., Tian, H., Terhune, D. B., Ciraulo, D. A., & Renshaw, P. F. (2007) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2007.6338 · Cited by 343 · see citing works
Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1
Borden, L. A., Dhar, T. G. M., Smith, K. E., et al. (1994) · European Journal of Pharmacology Molecular Pharmacology · doi:10.1016/0922-4106(94)90089-2 · Cited by 335 · see citing works
Effect of a γ-aminobutyric acid-enriched dairy product on the blood pressure of spontaneously hypertensive and normotensive Wistar–Kyoto rats
Hayakawa, K., Kimura, M., Kasahaa, K., Matsumoto, K., Sansawa, H., & Yamori, Y. (2004) · British Journal Of Nutrition · doi:10.1079/bjn20041221 · Cited by 330 · see citing works
Effect of the Defatted Rice Germ Enriched with GABA for Sleeplessness, Depression, Autonomic Disorder by Oral Administration.
OKADA, T., Sugishita, T., Murakami, T., Murai, H., Saikusa, T., Horino, T., ONODA, A., Kajimoto, O., TAKAHASHI, R., & TAKAHASHI, T. (2000) · NIPPON SHOKUHIN KOGYO GAKKAISHI · doi:10.3136/nskkk.47.596 · Cited by 263 · see citing works
GABA controls the level of quorum-sensing signal in Agrobacterium tumefaciens
Chevrot, R., Rosen, R., Haudecoeur, E., Beury-Cirou, A., Shelp, B. J., Ron, E. Z., & Faure, D. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0600313103 · Cited by 259 · see citing works
Rapid Accumulation of γ-Aminobutyric Acid and Alanine in Soybean Leaves in Response to an Abrupt Transfer to Lower Temperature, Darkness, or Mechanical Manipulation
Wallace, W., Secor, J., & SCHRADER, L. E. (1984) · PLANT PHYSIOLOGY · doi:10.1104/pp.75.1.170 · Cited by 250 · see citing works
Use of sourdough fermentation and pseudo-cereals and leguminous flours for the making of a functional bread enriched of γ-aminobutyric acid (GABA)
Coda, R., Rizzello, C. G., & Gobbetti, M. (2009) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2009.12.010 · Cited by 248 · see citing works
Production of gamma-aminobutyric acid by Lactobacillus brevis NCL912 using fed-batch fermentation
Li, H., Qiu, T., Huang, G., & Cao, Y. (2010) · Microbial Cell Factories · doi:10.1186/1475-2859-9-85 · Cited by 242 · see citing works
Production of the secondary metabolites γ-aminobutyric acid and monacolin K by Monascus
Su, Y., Wang, J., Lin, T.-T., & Pan, T. (2003) · Journal of Industrial Microbiology & Biotechnology · doi:10.1007/s10295-002-0001-5 · Cited by 241 · see citing works
Effects of Germinated Brown Rice Extracts with Enhanced Levels of GABA on Cancer Cell Proliferation and Apoptosis
Oh, C., & Oh, S. (2004) · Journal of Medicinal Food · doi:10.1089/109662004322984653 · Cited by 240 · see citing works
Metabolism, enzymology and possible roles of 4-aminobutyrate in higher plants
Narayan, V. S., & Nair, P. M. (1990) · Phytochemistry · doi:10.1016/0031-9422(90)85081-p · Cited by 237 · see citing works
Antioxidant and antihypertensive properties of liquid and solid state fermented lentils
Torino, M. I., Limón, R. I., Martínez‐Villaluenga, C., Mäkinen, S., Pihlanto, A., Vidal-Valverde, C., & Frı́as, J. (2012) · Food Chemistry · doi:10.1016/j.foodchem.2012.09.015 · Cited by 236 · see citing works
Germinated brown rice as a value added rice product: A review
Patil, S. B., & Khan, M. K. (2011) · Journal of Food Science and Technology · doi:10.1007/s13197-011-0232-4 · Cited by 236 · see citing works
Production of gamma-aminobutyric acid (GABA) by Lactobacillus buchneri isolated from kimchi and its neuroprotective effect on neuronal cells.
Cho, Y. R., Chang, J. Y., & Chang, H. C. (2007) · PubMed · Cited by 232 · see citing works
Production of γ-aminobutyric acid in black raspberry juice during fermentation by Lactobacillus brevis GABA100
Kim, J. Y., Lee, M. Y., Ji, G. E., Lee, Y. S., & Hwang, K. T. (2009) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2008.12.028 · Cited by 230 · see citing works
GABA in the endocrine pancreas: cellular localization and function in normal and diabetic rats
Adeghate, E., & Ponery, A. S. (2002) · Tissue and Cell · doi:10.1054/tice.2002.0217 · Cited by 223 · see citing works
Antioxidant activity and γ-aminobutyric acid (GABA) content in sea tangle fermented by Lactobacillus brevis BJ20 isolated from traditional fermented foods
Lee, B.-J., Kim, J., Kang, Y.-M., Lim, J.-H., Kim, Y., Lee, M., Jeong, M., Ahn, C., & Je, J. (2010) · Food Chemistry · doi:10.1016/j.foodchem.2010.02.071 · Cited by 208 · see citing works
Behavioral, Psychotic, and Anxiety Disorders in Epilepsy: Etiology, Clinical Features, and Therapeutic Implications
Torta, R., & Keller, R. (1999) · Epilepsia · doi:10.1111/j.1528-1157.1999.tb00883.x · Cited by 196 · see citing works
Synthesis of angiotensin i-converting enzyme (ACE)-inhibitory peptides and γ-aminobutyric acid (GABA) during sourdough fermentation by selected lactic acid bacteria.
Rizzello, C. G., Cassone, A., Di Cagno, R., & Gobbetti, M. (2008) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf800512u · Cited by 179 · see citing works
Synthesis of γ-aminobutyric acid (GABA) by Lactobacillus plantarum DSM19463: functional grape must beverage and dermatological applications
Cagno, R. D., Mazzacane, F., Rizzello, C. G., Angelis, M. D., Giuliani, G., Méloni, M., Servi, B. D., & Gobbetti, M. (2009) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-009-2370-4 · Cited by 177 · see citing works
Production of γ-aminobutyric acid by Streptococcus salivarius subsp. thermophilus Y2 under submerged fermentation
Yang, S.-Y., Lü, F., Lu, Z., Bie, X., Jiao, Y., Sun, L.-J., & Yu, B. (2007) · Amino Acids · doi:10.1007/s00726-007-0544-x · Cited by 174 · see citing works
Production of γ-Aminobutyric Acid By Cheese Starters During Cheese Ripening
Nomura, M., Kimoto, H., Someya, Y., Furukawa, S., & Suzuki, I. (1998) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(98)75714-5 · Cited by 171 · see citing works
The nitrogen content of the tomato leaf apoplast increases during infection by Cladosporium fulvum
Solomon, P. S., & Oliver, R. P. (2001) · Planta · doi:10.1007/s004250000500 · Cited by 166 · see citing works
Effect of green tea rich in ?-aminobutyric acid on blood pressure of Dahl salt-sensitive rats
ABE, Y., UMEMURA, S., SUGIMOTO, K., HIRAWA, N., KATO, Y., YOKOYAMA, N., YOKOYAMA, T., IWAI, J., & ISHII, M. (1995) · American Journal of Hypertension · doi:10.1016/0895-7061(94)00141-w · Cited by 160 · see citing works
Effect of Microbial Fermentation on Content of Statin, GABA, and Polyphenols in Pu-Erh Tea
Jeng, K.-C. G., Chen, C., Fang, Y.-P., Hou, R. C., & Chen, Y.-S. (2007) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf071629p · Cited by 155 · see citing works
Accumulation ofγ-Aminobutyric Acid (Gaba) in the Rice Germ during Water Soaking
Saikusa, T., Horino, T., & Mori, Y. (1994) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.58.2291 · Cited by 153 · see citing works
Gamma-aminobutyric acid production in black soybean milk by Lactobacillus brevis FPA 3709 and the antidepressant effect of the fermented product on a forced swimming rat model
Ko, C. Y., Lin, H.-T. V., & Tsai, G. J. (2013) · Process Biochemistry · doi:10.1016/j.procbio.2013.02.021 · Cited by 149 · see citing works
Gamma-aminobutyric acid, a potential tumor suppressor for small airway-derived lung adenocarcinoma
Schuller, H. M., Al-Wadei, H. A. N., & Majidi, M. (2008) · Carcinogenesis · doi:10.1093/carcin/bgn041 · Cited by 143 · see citing works
Effects of steeping and anaerobic treatment on GABA (γ-aminobutyric acid) content in germinated waxy hull-less barley
Chung, H., Jang, S.-H., Cho, H. Y., et al. (2009) · LWT · doi:10.1016/j.lwt.2009.04.007 · Cited by 141 · see citing works
The Production of a NewTempeh-like Fermented Soybean Containing a High Level of γ-Aminobutyric Acid by Anaerobic Incubation withRhizopus
Aoki, H., Ichiyo, U. D. A., Tagami, K., Furuya, Y., Endo, Y., & Fujimoto, K. (2003) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.67.1018 · Cited by 141 · see citing works
The GABAa receptor-gated ion channel: Biochemical and pharmacological studies of structure and function
Schwartz, R. D. (1988) · Biochemical Pharmacology · doi:10.1016/0006-2952(88)90684-3 · Cited by 138 · see citing works
Cloning, sequencing and expression of a novel glutamate decarboxylase gene from a newly isolated lactic acid bacterium, Lactobacillus brevis OPK-3
Park, K.-B., & Oh, S. (2006) · Bioresource Technology · doi:10.1016/j.biortech.2006.01.004 · Cited by 134 · see citing works
Lactococcus lactis contains only one glutamate decarboxylase gene.
Nomura, M., Nakajima, I., Fujita, Y., Kobayashi, M., Kimoto, H., Suzuki, I., & Aso, H. (1999) · Microbiology · doi:10.1099/13500872-145-6-1375 · Cited by 130 · see citing works
Kinetic differences between the isoforms of glutamate decarboxylase: implications for the regulation of GABA synthesis
Battaglioli, G., Liu, H., & Martin, D. L. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.01910.x · Cited by 126 · see citing works
Production of .GAMMA.-Aminobutyric Acid from Alcohol Distillery Lees by Lactobacillus brevis IFO-12005.
Yokoyama, S., HIRAMATSU, J., & HAYAKAWA, K. (2002) · Journal of Bioscience and Bioengineering · doi:10.1263/jbb.93.95 · Cited by 126 · see citing works
Anti-Hypertensive Effect of γ-Aminobutyric Acid (GABA)-Rich<i>Chlorella</i>on High-Normal Blood Pressure and Borderline Hypertension in Placebo-Controlled Double Blind Study
Shimada, M., Hasegawa, T., Nishimura, C., Kan, H., Kanno, T., Nakamura, T., & Matsubayashi, T. (2009) · Clinical and Experimental Hypertension · doi:10.1080/10641960902977908 · Cited by 124 · see citing works
Production of γ-aminobutyric acid from alcohol distillery lees by Lactobacillus brevis IFO-12005
Yokoyama, S., HIRAMATSU, J., & Hayakawa, K. (2002) · Journal of Bioscience and Bioengineering · doi:10.1016/s1389-1723(02)80061-5 · Cited by 123 · see citing works
γ-Aminobutyric acid : a constituent of the potato tuber?
Steward, F. C. (1949) · Science · Cited by 122 · see citing works
Manufacture of a functional fermented milk enriched of Angiotensin-I Converting Enzyme (ACE)-inhibitory peptides and γ-amino butyric acid (GABA)
Nejati, F., Rizzello, C. G., Cagno, R. D., Sheikh‐Zeinoddin, M., Diviccaro, A., Minervini, F., & Gobbetti, M. (2012) · LWT · doi:10.1016/j.lwt.2012.09.017 · Cited by 121 · see citing works
Psychological stress-reducing effect of chocolate enriched with γ-aminobutyric acid (GABA) in humans: assessment of stress using heart rate variability and salivary chromogranin A.
Nakamura, H., Takishima, T., Kometani, T., & Yokogoshi, H. (2009) · International Journal of Food Sciences and Nutrition · doi:10.1080/09637480802558508 · Cited by 116 · see citing works
Germinated Brown Rice Extract Shows a Nutraceutical Effect in the Recovery of Chronic Alcohol-Related Symptoms
Oh, S., Soh, J., & Cha, Y. (2003) · Journal of Medicinal Food · doi:10.1089/109662003322233512 · Cited by 110 · see citing works
Differences between GABA levels in Alzheimer's disease and Down syndrome with Alzheimer-like neuropathology
Seidl, R., Cairns, N. J., Singewald, N., Kaehler, S. T., & Lübec, G. (2001) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s002100000346 · Cited by 109 · see citing works
Glutamic acid and gamma-aminobutyric acid neurotransmitters in central control of breathing
Kazemi, H., & Hoop, B. (1991) · Journal of Applied Physiology · doi:10.1152/jappl.1991.70.1.1 · Cited by 108 · see citing works
Biosynthesis of γ-aminobutyric acid (GABA) using immobilized whole cells of Lactobacillus brevis.
Huang, J., Mei, L.-H., Wu, H., & Lin, D.-Q. (2007) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-006-9311-5 · Cited by 107 · see citing works
Medium optimization for production of gamma-aminobutyric acid by Lactobacillus brevis NCL912
Li, H., Qiu, T., Gao, D., & Cao, Y. (2009) · Amino Acids · doi:10.1007/s00726-009-0355-3 · Cited by 105 · see citing works
Accumulation of γ‐aminobutyric acid in nodulated soybean in response to drought stress
Serraj, R., Shelp, B. J., & Sinclair, T. R. (1998) · Physiologia Plantarum · doi:10.1034/j.1399-3054.1998.1020111.x · Cited by 105 · see citing works
Thyroid hormone and γ-aminobutyric acid (GABA) interactions in neuroendocrine systems
Wiens, S. C., & Trudeau, V. L. (2006) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/j.cbpa.2006.01.033 · Cited by 105 · see citing works
Antihypertensive Effect of a γ-Aminobutyric Acid Rich Tomato Cultivar ‘DG03-9’ in Spontaneously Hypertensive Rats
Yoshimura, M., Toyoshi, T., Sano, A., Izumi, T., Fujii, T., Konishi, C., Inai, S., Matsukura, C., Fukuda, N., Ezura, H., et al. (2009) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf903008t · Cited by 101 · see citing works
Wound healing activity of gamma-aminobutyric Acid (GABA) in rats.
Han, D., Kim, H.-Y., Lee, H., et al. (2007) · PubMed · Cited by 99 · see citing works
Fermented goats’ milk produced with selected multiple starters as a potentially functional food
Minervini, F., Bilancia, M. T., Siragusa, S., Gobbetti, M., & Caponio, F. (2009) · Food Microbiology · doi:10.1016/j.fm.2009.03.008 · Cited by 99 · see citing works
ACE-inhibitory activity and gamma-aminobutyric acid content of fermented skim milk by Lactobacillus helveticus isolated from Xinjiang koumiss in China
Sun, T., Zhao, S., Wang, H., Cai, C., Chen, Y., & Zhang, H. (2008) · European Food Research and Technology · doi:10.1007/s00217-008-0969-9 · Cited by 98 · see citing works
Effect of cheese containing gamma-aminobutyric acid-producing lactic acid bacteria on blood pressure in men
Pouliot-Mathieu, K., Gardner-Fortier, C., Lemieux, S., St-Gelais, D., Champagne, C. P., & Vuillemard, J.-C. (2013) · PharmaNutrition · doi:10.1016/j.phanu.2013.06.003 · Cited by 96 · see citing works
Antihypertensive effect of mulberry leaf aqueous extract containing γ-aminobutyric acid in spontaneously hypertensive rats
Yang, N.-C., Jhou, K.-Y., & Tseng, C. (2011) · Food Chemistry · doi:10.1016/j.foodchem.2011.11.143 · Cited by 96 · see citing works
Plasma concentrations of gamma-aminobutyric acid (GABA) and mood disorders: a blood test for manic depressive disease?
Petty, F. (1994) · Clinical Chemistry · doi:10.1093/clinchem/40.2.296 · Cited by 95 · see citing works
Determination and Comparison of γ-Aminobutyric Acid (GABA) Content in Pu-erh and Other Types of Chinese Tea
Zhao, M., Ma, Y., Wei, Z., Yuan, W.-X., Li, Y., Zhang, C., Xue, X., & Zhou, H. (2011) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf104601v · Cited by 94 · see citing works
Plasma GABA levels correlate with aggressiveness in relatives of patients with unipolar depressive disorder
Bjork, J. M., Moeller, F. G., Kramer, G. L., Kram, M., Surís, A., Rush, A. J., & Petty, F. (2001) · Psychiatry Research · doi:10.1016/s0165-1781(01)00220-7 · Cited by 92 · see citing works
Basic Mechanisms of Gabitril (Tiagabine) and Future Potential Developments
Meldrum, B. S., & Chapman, A. G. (1999) · Epilepsia · doi:10.1111/j.1528-1157.1999.tb02087.x · Cited by 92 · see citing works
Synthesis of γ-aminobutyric acid by expressing Lactobacillus brevis-derived glutamate decarboxylase in the Corynebacterium glutamicum strain ATCC 13032
Shi, F., & Li, Y. (2011) · Biotechnology Letters · doi:10.1007/s10529-011-0723-4 · Cited by 91 · see citing works
Influence of preprocessing methods and fermentation of adzuki beans on γ-aminobutyric acid (GABA) accumulation by lactic acid bacteria
Liao, W.-C., Wang, C., Shyu, Y., Yu, R., & Ho, K.-C. (2013) · Journal of Functional Foods · doi:10.1016/j.jff.2013.03.006 · Cited by 86 · see citing works
The Osmolyte Strategy of Normal Human Keratinocytes in Maintaining Cell Homeostasis
Warskulat, U., Reinen, A., Grether‐Beck, S., Krutmann, J., & Häussinger, D. (2004) · Journal of Investigative Dermatology · doi:10.1111/j.0022-202x.2004.23313.x · Cited by 85 · see citing works
Effects of dietary glutamine and gamma-aminobutyric acid on meat colour, pH, composition, and water-holding characteristic in broilers under cyclic heat stress
Dai, S., Gao, F., Xinglian, X., et al. (2012) · British Poultry Science · doi:10.1080/00071668.2012.719148 · Cited by 85 · see citing works
Antihypertensive Effects of Lactobacillus-Fermented Milk Orally Administered to Spontaneously Hypertensive Rats
Liu, C. F., Tung, Y. T., Wu, C. L., Lee, B., Hsu, W.-H., & Pan, T. (2011) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf104985v · Cited by 83 · see citing works
Germinated brown rice regulates hepatic cholesterol metabolism and cardiovascular disease risk in hypercholesterolaemic rats
Imam, M. U., Ishaka, A., Ooi, D. J., Zamri, N. D. M., Sarega, N., Ismail, M., & Esa, N. M. (2014) · Journal of Functional Foods · doi:10.1016/j.jff.2014.03.013 · Cited by 80 · see citing works
Isolation of γ-aminobutyric acid-producing bacteria and optimization of fermentative medium
Lu, X., Chen, Z., Gu, Z., & Han, Y. (2008) · Biochemical Engineering Journal · doi:10.1016/j.bej.2008.03.005 · Cited by 80 · see citing works
Evaluation of γ- aminobutyric acid, phytate and antioxidant activity of tempeh-like fermented oats (Avena sativa L.) prepared with different filamentous fungi
Cai, S., Gao, F., Zhang, X., et al. (2012) · Journal of Food Science and Technology · doi:10.1007/s13197-012-0748-2 · Cited by 77 · see citing works
Manganese deficiency leads to elevated amino acid pools in citric acid accumulating Aspergillus niger
Kubicek, C. P., Hampel, W. A., & R�hr, M. (1979) · Archives of Microbiology · doi:10.1007/bf00403504 · Cited by 76 · see citing works
Relieving Occupational Fatigue by Consumption of a Beverage Containing γ-Amino Butyric Acid
Kanehira, T., Nakamura, Y., Nakamura, K., Horie, K., Noriko, H., FURUGORI, K., Sauchi, Y., & Yokogoshi, H. (2011) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.57.9 · Cited by 75 · see citing works
Neurospora crassa conidial germination: role of endogenous amino acid pools
Schmit, J. C., & Brody, S. (1975) · Journal of Bacteriology · doi:10.1128/jb.124.1.232-242.1975 · Cited by 74 · see citing works
Stimulation of γ-Aminobutyric Acid Synthesis Activity in Brown Rice by a Chitosan/Glutamic Acid Germination Solution and Calcium/Calmodulin
Oh, S. (2003) · BMB Reports · doi:10.5483/bmbrep.2003.36.3.319 · Cited by 74 · see citing works
γ -Aminobutyric Acid (GABA) Content of Selected Uncooked Foods
Oh, S., Moon, Y.-J., & Oh, C. (2003) · Preventive Nutrition and Food Science · doi:10.3746/jfn.2003.8.1.075 · Cited by 70 · see citing works
A role for glutamate decarboxylase during tomato ripening: the characterisation of a cDNA encoding a putative glutamate decarboxylase with a calmodulin-binding site
Gallego, P. P. F., Whotton, L., Picton, S. J., et al. (1995) · Plant Molecular Biology · doi:10.1007/bf00020887 · Cited by 69 · see citing works
Spanish cheese screening and selection of lactic acid bacteria with high gamma-aminobutyric acid production
Diana, M., Tres, A., Quı́lez, J., Llombart, M., & Rafecas, M. (2013) · LWT · doi:10.1016/j.lwt.2013.11.027 · Cited by 66 · see citing works
Self-citation
Purification and Characterization of Glutamate Decarboxylase of Lactobacillus brevis CGMCC 1306 Isolated from Fresh Milk
Huang, J., Mei, L., Sheng, Q., Yao, S., & Lin, D. (2007) · Chinese Journal of Chemical Engineering · doi:10.1016/s1004-9541(07)60051-2 · Cited by 64 · see citing works
GABA content and GAD activity in colon tumors taken from patients with colon cancer or from xenografted human colon cancer cells growing as s.c. tumors in athymic nu/nu mice.
Kleinrok, Z., Matuszek, M., Jesipowicz, J., et al. (1998) · PubMed · Cited by 63 · see citing works
Antihypertensive and Natriuretic Effects of Less-Sodium Soy Sauce Containing γ-Aminobutyric Acid in Spontaneously Hypertensive Rats
Yamakoshi, J., Fukuda, S., SATOH, T., 辻亮平, SAITO, M., Obata, A., Matsuyama, A., Kikuchi, M., & Kawasaki, T. (2007) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.60424 · Cited by 62 · see citing works
Hypotensive Effect of Fermented Milk Containing .GAMMA.-Aminobutyric Acid (GABA) in Subjects with High Normal Blood Pressure
Kajimoto, O., Hirata, H., Nakagawa, S., et al. (2004) · NIPPON SHOKUHIN KOGYO GAKKAISHI · doi:10.3136/nskkk.51.79 · Cited by 62 · see citing works
Production and Characterization of Kimchi with Enhanced Levels of γ-Aminobutyric Acid
Seok, J.-H., Park, K. B., Kim, Y. H., Bae, M.-J., & Lee, M. K. (2008) · Food Science and Biotechnology · Cited by 61 · see citing works
Microbial and chemical properties of aji-no-susu, a traditional fermented fish with rice product in the Noto Peninsula, Japan
Kuda, T., Tanibe, R., Mori, M., Take, H., Michihata, T., Yano, T., Takahashi, H., & Kimura, B. (2009) · Fisheries Science · doi:10.1007/s12562-009-0175-0 · Cited by 60 · see citing works
Enhancement of γ-aminobutyric acid in a fermented red seaweed beverage by starter culture Lactobacillus plantarum DW12
Kantachote, D., Ratanaburee, A., Charernjiratrakul, W., Penjamras, P., & Chaiyasut, C. (2011) · Electronic Journal of Biotechnology · doi:10.2225/vol14-issue3-fulltext-2 · Cited by 59 · see citing works
Alpha-linolenic acid: A promising nutraceutical for the prevention of stroke
Nguemeni, C., Gouix, E., Bourourou, M., Heurteaux, C., & Blondeau, N. (2013) · PharmaNutrition · doi:10.1016/j.phanu.2012.12.002 · Cited by 59 · see citing works
Rapid glutamate decarboxylase assay for detection of Escherichia coli
Rice, E. W., Johnson, C. H., Dunnigan, M. E., et al. (1993) · Applied and Environmental Microbiology · doi:10.1128/aem.59.12.4347-4349.1993 · Cited by 58 · see citing works
Accumulation of γ-Aminobutyric Acid in Rice Germ Using Protease
Zhang, H., Hui-yuan, Y., & Chen, F. (2006) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.70.1160 · Cited by 58 · see citing works
GABA-synthesizing enzyme, GAD67, from dermal fibroblasts: Evidence for a new skin function
Ito, K., Tanaka, K., Yukinobu, N., Hasegawa, J., & Ueno, H. (2006) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2006.09.017 · Cited by 57 · see citing works
The role of GABA-ergic system in human mammary gland pathology and in growth of transplantable murine mammary cancer.
Opolski, A., Mazurkiewicz, M., Wietrzyk, J., et al. (2000) · PubMed · Cited by 55 · see citing works
Treatment of Germinated Wheat to Increase Levels of GABA and IP6 Catalyzed by Endogenous Enzymes
Nagaoka, H. (2005) · Biotechnology Progress · doi:10.1021/bp0496777 · Cited by 55 · see citing works
Antihypertensive effect of γ‐amino butyric acid enriched soy products in spontaneously hypertensive rats
Shizuka, F., Kido, Y., Nakazawa, T., Kitajima, H., Aizawa, C., Kayamura, H., & Ichijo, N. (2004) · BioFactors · doi:10.1002/biof.5520220133 · Cited by 53 · see citing works
Treatment strategies for a rheumatoid arthritis patient with interstitial lung disease
Kelly, C. A., & Saravanan, V. (2008) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656560802591430 · Cited by 53 · see citing works
Comparison of gamma-aminobutyric acid production in Thai rice grains
Jannoey, P., Niamsup, H., Lumyong, S., Suzuki, T., Katayama, T., & Chairote, G. (2009) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-009-0168-2 · Cited by 53 · see citing works
Selection of γ‐aminobutyric acid‐producing lactic acid bacteria and their potential as probiotics for use as starter cultures in T hai fermented sausages ( N ham)
Ratanaburee, A., Kantachote, D., Charernjiratrakul, W., & Sukhoom, A. (2013) · International Journal of Food Science & Technology · doi:10.1111/ijfs.12098 · Cited by 52 · see citing works
Effects of cultivar and culture conditions on γ‐aminobutyric acid accumulation in germinated fava beans ( Vicia faba L.)
Li, Y., Bai, Q., Jin, X., Wen, H., & Gu, Z. (2009) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.3778 · Cited by 52 · see citing works
Gamma-aminobutyric acid-producing abilities of lactococcal strains isolated from old-style cheese starters
Lacroix, N., St‐Gelais, D., Champagne, C. P., & Vuillemard, J.-C. (2013) · Dairy Science and Technology · doi:10.1007/s13594-013-0127-4 · Cited by 52 · see citing works
The amino acid sequence of glutamate decarboxylase from Escherichia coli
Maras, B., Sweeney, G. E., Barra, D., Bossa, F., & John, R. A. (1992) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1992.tb16609.x · Cited by 50 · see citing works
Enhancement of γ-aminobutyric acid production in Chungkukjang by applying a Bacillus subtilis strain expressing glutamate decarboxylase from Lactobacillus brevis
Park, K.-B., & Oh, S. (2006) · Biotechnology Letters · doi:10.1007/s10529-006-9112-9 · Cited by 50 · see citing works
Isolation of Marine Yeasts Collected from the Pacific Ocean Showing a High Production of γ-Aminobutyric Acid
MASUDA, K., Guo, X., Uryu, N., Hagiwara, T., & Watabe, S. (2008) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.80544 · Cited by 50 · see citing works
Elevated γ‐Aminobutyric Acid Levels Attenuate the Metabolic Response to Biateral Ischemia
Abel, M. S., & McCandless, D. W. (1992) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1992.tb09780.x · Cited by 49 · see citing works
Cloning of the gene for glutamate decarboxylase and its expression during conidiation in Neurospora crassa
Hao, R., & Schmit, J. C. (1993) · Biochemical Journal · doi:10.1042/bj2930735 · Cited by 49 · see citing works
Purification and characterization of glutamate decarboxylase from cowpea
Johnson, B. S., Singh, N. K., Cherry, J. H., et al. (1997) · Phytochemistry · doi:10.1016/s0031-9422(97)00236-7 · Cited by 48 · see citing works
Gamma-aminobutyric acid improves oxidative stress and function of the thyroid in high-fat diet fed mice
Xie, Z., Xia, S., & Le, G. (2014) · Journal of Functional Foods · doi:10.1016/j.jff.2014.03.003 · Cited by 47 · see citing works
Use ofLactococcus lactisto enrich sourdough bread with γ-aminobutyric acid
Bhanwar, S., Bamnia, M., Ghosh, M., & Ganguli, A. (2012) · International Journal of Food Sciences and Nutrition · doi:10.3109/09637486.2012.700919 · Cited by 45 · see citing works
Increasing the bio-active compounds contents by optimizing the germination conditions of Southern Thai Brown Rice
Banchuen, J., Thammarutwasik, P., Ooraikul, B., et al. (2010) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 45 · see citing works
Enhancement of γ-Amminobutyric Acid Production by Lactobacillus sakei B2-16 Expressing Glutamate Decarboxylase from Lactobacillus plantarum ATCC 14917
Kook, M. (2010) · Journal of the Korean Society for Applied Biological Chemistry · doi:10.3839/jksabc.2010.123 · Cited by 45 · see citing works
GABA Receptor molecules of insects
Anthony, N. M., Harrison, J. B., & Sattelle, D. B. (1993) · Birkhäuser Basel eBooks · doi:10.1007/978-3-0348-7265-2_8 · Cited by 44 · see citing works
In situ production of γ-aminobutyric acid in breakfast cereals
Joye, I. J., Lamberts, L., Brijs, K., & Delcour, J. A. (2011) · Food Chemistry · doi:10.1016/j.foodchem.2011.04.090 · Cited by 44 · see citing works
Effects of culture conditions on γ-aminobutyric acid accumulation during germination of foxtail millet (Setaria italica L.)
Bai, Q., Fan, G., Gu, Z., et al. (2008) · European Food Research and Technology · doi:10.1007/s00217-008-0920-0 · Cited by 44 · see citing works
Establishment of an Efficient Fermentation System of Gamma-Aminobutyric Acid by a Lactic Acid Bacterium, Enterococcus avium G-15, Isolated from Carrot Leaves
Tamura, T., Noda, M., Ozaki, M., Maruyama, M., Matoba, Y., Kumagai, T., & Sugiyama, M. (2010) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.33.1673 · Cited by 43 · see citing works
Study on quality components and sleep-promoting effect of GABA Maoyecha tea
Wu, C., Huang, Y., Lai, X., Lai, R., Zhao, W., Zhang, M., & Zhao, W. (2014) · Journal of Functional Foods · doi:10.1016/j.jff.2014.02.013 · Cited by 42 · see citing works
A New Probiotic Cheddar Cheese with High ACE-Inhibitory Activity and γ-Aminobutyric Acid Content Produced with Koumiss-Derived Lactobacillus casei Zhang
Wang, H. K., Dong, C., Chen, Y. F., Cui, L. M., & Zhang, H. P. (2010) · University of Zagreb University Computing Centre (SRCE) · Cited by 42 · see citing works
Protective role of γ-aminobutyric acid against chronic renal failure in rats
Sasaki, S., Yokozawa, T., Cho, E. J., et al. (2006) · Journal of Pharmacy and Pharmacology · doi:10.1211/jpp.58.11.0013 · Cited by 41 · see citing works
Manufacture of Processed Brown Rice Enriched with GABA Accumulation Using High Pressure Treatment. Part I. Accumulation of GABA in Brown Rice by High Pressure Treatment.
Kinefuchi, M., SEKIYA, M., Yamazaki, A., et al. (1999) · NIPPON SHOKUHIN KOGYO GAKKAISHI · doi:10.3136/nskkk.46.323 · Cited by 40 · see citing works
Production and Characterization of GABA Rice Yogurt
Park, K.-B., & Oh, S. (2005) · Food Science and Biotechnology · Cited by 39 · see citing works
Isolation, characterization, and utilization of γ-aminobutyric acid (GABA)-producing lactic acid bacteria from Myanmar fishery products fermented with boiled rice
Thwe, S. M., Kobayashi, T., Luan, T., Shirai, T., Onodera, M., Hamada‐Sato, N., & Imada, C. (2011) · Fisheries Science · doi:10.1007/s12562-011-0328-9 · Cited by 39 · see citing works
Dietary γ-Aminobutyric Acid Affects the Brain Protein Synthesis Rate in Ovariectomized Female Rats
Tujioka, K., Ohsumi, M., Horie, K., Kim, M., HAYASE, K., & Yokogoshi, H. (2009) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.55.75 · Cited by 37 · see citing works
Cloning and Nucleotide Sequence of the Glutamate Decarboxylase-encoding GenegadAfromAspergillus oryzae
Kato, Y., Kato, Y., Furukawa, K., et al. (2002) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.66.2600 · Cited by 36 · see citing works
Isolation and characterization of Dioclea altissima var. megacarpa seed lectin
Moreira, R. D. A., Monteiro‐Moreira, A. C. D. O., Horta, A. C. G., et al. (1997) · Phytochemistry · doi:10.1016/s0031-9422(97)00262-8 · Cited by 36 · see citing works
Gaba and hepatocellular carcinoma
Minuk, G. Y. (2000) · Molecular and Cellular Biochemistry · doi:10.1023/a:1007062802164 · Cited by 36 · see citing works
GABA tea ameliorates cerebral cortex apoptosis and autophagy in streptozotocin-induced diabetic rats
Huang, C., Kuo, W., Wang, H. F., Lin, C.-J., Lin, Y.-M., Chen, J.-L., Kuo, C., Chen, P. K., & Lin, J.-Y. (2013) · Journal of Functional Foods · doi:10.1016/j.jff.2013.11.020 · Cited by 35 · see citing works
The Effects of γ-Aminobutyric Acid, Vinegar, and Dried Bonito on Blood Pressure in Normotensive and Mildly or Moderately Hypertensive Volunteers
Tanaka, H., Watanabe, K., Ma, M., et al. (2009) · Journal of Clinical Biochemistry and Nutrition · doi:10.3164/jcbn.09-04 · Cited by 35 · see citing works
Dynamics of γ-aminobutyric acid in wheat flour bread making
Lamberts, L., Joye, I. J., Beliën, T., & Delcour, J. A. (2011) · Food Chemistry · doi:10.1016/j.foodchem.2011.08.004 · Cited by 33 · see citing works
Potential of PSA-NCAM in neuron-glial plasticity in the adult hypothalamus: Role of noradrenergic and GABAergic neurotransmitters
Parkash, J., & Kaur, G. (2007) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2007.07.005 · Cited by 26 · see citing works
Modulation of GABA Receptors Expressed inXenopusOocytes by 13- l -Hydoxylinoleic Acid and Food Additives
Aoshima, H., & Tenpaku, Y. (1997) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.61.2051 · Cited by 26 · see citing works
Ornithine and glutamate decarboxylases catalyse an oxidative deamination of their alpha-methyl substrates.
Bertoldi, M., Carbone, V., & Voltattorni, C. B. (1999) · PubMed · Cited by 25 · see citing works
Effects of GABA supplementation on blood pressure and safety in adults with mild hypertension
Matsubara, F., Ueno, H., Tadano, K., et al. (2002) · Yakuri to chiryō · Cited by 24 · see citing works
GABA, a New Player in the Plant Mating Game
Yang, Z. (2003) · Developmental Cell · doi:10.1016/s1534-5807(03)00236-3 · Cited by 22 · see citing works
Effects of Autogenic Training and Antihypertensive Agents on Circadian and Circaseptan Variation of Blood Pressure
Watanabe, Y., Cornélissen, G., Watanabe, M., et al. (2003) · Clinical and Experimental Hypertension · doi:10.1081/ceh-120024984 · Cited by 22 · see citing works
Effects of Vegetable Containing Gamma-Aminobutyric Acid on the Cardiac Autonomic Nervous System in Healthy Young People
Okita, Y., Nakamura, H., Kouda, K., et al. (2009) · Journal of PHYSIOLOGICAL ANTHROPOLOGY · doi:10.2114/jpa2.28.101 · Cited by 22 · see citing works
Effects of co-culturing LAB on GABA production
Watanabe, Y., Hayakawa, K., & Ueno, H. (2011) · Medical Entomology and Zoology · Cited by 21 · see citing works
Utilization of Barley or Wheat Bran to Bioconvert Glutamate to γ‐Aminobutyric Acid (GABA)
Jin, W., Kim, M., & Kim, K. (2013) · Journal of Food Science · doi:10.1111/1750-3841.12234 · Cited by 20 · see citing works
Muscimol binding and GABA receptors
DeFeudis, F. V. (1981) · Drug Development Research · doi:10.1002/ddr.430010202 · Cited by 20 · see citing works
Progesterone, GABA and mood disorders in women
Rapkin, A. J. (1999) · Archives of Women s Mental Health · doi:10.1007/s007370050041 · Cited by 19 · see citing works
Physicochemical and functional characteristics of a novel fermented pepper (Capsiccum annuum L.) leaves-based beverage using lactic acid bacteria
Song, Y., Shin, N., & Baik, S. (2013) · Food Science and Biotechnology · doi:10.1007/s10068-014-0025-4 · Cited by 18 · see citing works
Identification of High γ-Aminobutyric Acid Producing Marine Yeast Strains by Physiological and Biochemical Characteristics and Gene Sequence Analyses
Guo, X., Hitoshi, A. O. K. I., Hagiwara, T., et al. (2009) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.90014 · Cited by 17 · see citing works
Hypotension and hypothalamic depression produced by intracerebroventricular injections of GABA in spontaneously hypertensive rats.
Sasaki, S., Lee, L.-C., Nakamura, Y., et al. (1986) · Japanese Circulation Journal-english Edition · doi:10.1253/jcj.50.1140 · Cited by 17 · see citing works
Contents of .GAMMA.-Aminobutyric Acid (GABA) in Potatoes and Processed Potato Products
Nakamura, K., Nara, K., Noguchi, T., et al. (2006) · NIPPON SHOKUHIN KOGYO GAKKAISHI · doi:10.3136/nskkk.53.514 · Cited by 16 · see citing works
A SIMPLE METHOD FOR RAPID SCREENING OF BACTERIA WITH GLUTAMATE DECARBOXYLASE ACTIVITIES
Yang, S.-Y., Lu, Z., Lü, F., Bie, X., SUN, L., & Zeng, X. (2006) · Journal of Rapid Methods & Automation in Microbiology · doi:10.1111/j.1745-4581.2006.00054.x · Cited by 16 · see citing works
A membrane form of brain L-glutamate decarboxylase: identification, isolation, and its relation to insulin-dependent mellitus.
Nathan, B., Bao, J., Hsu, C. C., Aguilar, P., Wu, R., Yarom, M., Kuo, C. Y., & Wu, J. ‐. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.1.242 · Cited by 16 · see citing works
Development of GABA-enhanced Lactic Acid Beverage using Sugar Cane and its Functionality
Hirose, N., Ujihara, K., TERUYA, R., et al. (2008) · NIPPON SHOKUHIN KOGYO GAKKAISHI · doi:10.3136/nskkk.55.209 · Cited by 13 · see citing works
Antihypertensive Effects of GABA-Enriched Potato Snacks in Spontaneously Hypertensive Rats
Noguchi, T., Nakamura, K., Nagai, T., et al. (2007) · NIPPON SHOKUHIN KOGYO GAKKAISHI · doi:10.3136/nskkk.54.75 · Cited by 13 · see citing works
Antihypertensive Effect of Honey-Based Beverage Containing Fermented Rice Bran in Spontaneously Hypertensive Rats
Hiwatashi, K., Narisawa, A., Hokari, M., et al. (2010) · NIPPON SHOKUHIN KOGYO GAKKAISHI · doi:10.3136/nskkk.57.40 · Cited by 13 · see citing works
Effects of anti-hypertension and intestinal microflora of spontaneously hypertensive rats fed gamma- aminobutyric acid-enriched Chingshey purple sweet potato fermented milk by lactic acid bacteria
Tsai, C., Chiu, T., Ho, C.-Y., Lin, P., & Wu, T.-Y. (2013) · Cited by 13 · see citing works
Effect of protein and lactulose on the production of gamma-aminobutyric acid by faecal Escherichia coli.
Mardini, H. A., al Jumaili, B., Record, C. O., et al. (1991) · Gut · doi:10.1136/gut.32.9.1007 · Cited by 10 · see citing works
Effect of pH, temperature and salinity on the production of gamma aminobutyric acid (GABA) from amines by marine bacteria
Mountfort, D. O., & Pybus, V. (1992) · FEMS Microbiology Ecology · doi:10.1111/j.1574-6941.1992.tb01660.x · Cited by 10 · see citing works
The influence of fig proteases on the inhibition of angiotensin I‐converting and GABA formation in meat
Li, J., IZUMIMOTO, M., YONEHARA, M., et al. (2009) · Animal Science Journal · doi:10.1111/j.1740-0929.2009.00682.x · Cited by 7 · see citing works
Stability of Gamma-Aminobutyric Acid in Fruit Juice during Storage
Shimizu, T., & Sawai, Y. (2008) · food preservation science · doi:10.5891/jafps.34.145 · Cited by 5 · see citing works
Ornithine and glutamate decarboxylases catalyse an oxidative deamination of their α-methyl substrates
Bertoldi, M., Carbone, V., & Voltattorni, C. B. (1999) · Biochemical Journal · doi:10.1042/0264-6021:3420509 · Cited by 5 · see citing works
Accumulation of γ-aminobutyric acid and transcription of glutamate decarboxylase in Brassica juncea (L.) Czern.
Kim, Y. B., Lee, M., Kim, S., et al. (2013) · Cited by 4 · see citing works
Development of Laozao enriched with GABA
Cheng, Y. (2008) · Food Science and Technology International · Cited by 4 · see citing works
Production of γ-aminobutylic acid by lactic acid bacteria
Enterprises, M. (1997) · Journal of Fermentation and Bioengineering · doi:10.1016/s0922-338x(97)82554-8 · Cited by 4 · see citing works
Effect of Porphyra Extract on Blood Pressure in Spontaneously Hypertensive Rats
Umekawa, H., Tatsuno, T., Wang, Y., et al. (2008) · NIPPON SHOKUHIN KOGYO GAKKAISHI · doi:10.3136/nskkk.55.502 · Cited by 3 · see citing works

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Authors: Diana, M., Quílez, J., & Rafecas, M.
Affiliations: Europastry (Spain) (ES)
Corresponding author: Diana, Marina
Venue: Journal of Functional Foods
Publisher: Elsevier BV
Published: 2014-09
Volume: 10
Pages: 407-420
ISSN: 1756-4646 (ISSN-L)
DOI: 10.1016/j.jff.2014.07.004
OpenAlex: W1990867868
Cited by: 473
References: 158
Citations by year: 2026: 29 · 2025: 43 · 2024: 42 · 2023: 63 · 2022: 68 · 2021: 51 · 2020: 60 · 2019: 29 · 2018: 40 · 2017: 20 · 2016: 19 · 2015: 8
FWCI: 18.31
Type: journal article
Language: en
Open access: green
doaj.org
Licence: cc-by-sa
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Journal of Functional Foods (publishedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders: Europastry, S.A., through the grant program of the Centre for Industrial Technological Development IDI-20110755.
Topics: Life Sciences › Agricultural and Biological Sciences › Plant Science › GABA and Rice Research
Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Hydrolysis and Bioactive Peptides
Keywords: GABA, bioactive compounds, lactic acid bacteria, fermented foods, antihypertensive effect, GABA synthesis, functional foods, health benefits

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