Protective Role of Mitochondrial Peroxiredoxin III against UVB-Induced Apoptosis of Epidermal Keratinocytes

How mitochondria produce reactive oxygen species

Murphy, M. P. (2009) · Biochemical Journal · doi:10.1042/bj20081386 · Cited by 8,207 · see citing works

Reactive oxygen species, cellular redox systems, and apoptosis

Circu, M. L., & Aw, T. Y. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2009.12.022 · Cited by 3,340 · see citing works

Mitochondrial control of cell death

Kroemer, G., & Reed, J. C. (2000) · Nature Medicine · doi:10.1038/74994 · Cited by 3,103 · see citing works

Mitochondrial diseases in man and mouse

Wallace, D. C. (1999) · Science · doi:10.1126/science.283.5407.1482 · Cited by 3,060 · see citing works

Physiological Roles of Mitochondrial Reactive Oxygen Species

Sena, L. A., & Chandel, N. S. (2012) · Molecular Cell · doi:10.1016/j.molcel.2012.09.025 · Cited by 2,632 · see citing works

Mitochondrial fusion and fission in cell life and death

Westermann, B. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3013 · Cited by 2,002 · see citing works

Chemistry and biology of reactive oxygen species in signaling or stress responses

Dickinson, B. C., & Chang, C. J. (2011) · Nature Chemical Biology · doi:10.1038/nchembio.607 · Cited by 1,821 · see citing works

Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations

Kalyanaraman, B., Darley-Usmar, V. M., Davies, K. J. A., Dennery, P. A., Forman, H. J., Grisham, M. B., Mann, G. E., Moore, K. P., Roberts, L. J., & Ischiropoulos, H. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.09.030 · Cited by 1,795 · see citing works

Mitochondrial ROS Signaling in Organismal Homeostasis

Shadel, G. S., & Horvath, T. L. (2015) · Cell · doi:10.1016/j.cell.2015.10.001 · Cited by 1,353 · see citing works

Mitochondria

Newmeyer, D. D., & Ferguson-Miller, S. M. (2003) · Cell · doi:10.1016/s0092-8674(03)00116-8 · Cited by 1,268 · see citing works

Mitochondrial Oxidative Stress: Implications for Cell Death

Orrenius, S., Gogvadze, V. G., & Zhivotovsky, B. (2006) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.47.120505.105122 · Cited by 1,266 · see citing works

Genetically encoded fluorescent indicator for intracellular hydrogen peroxide

Belousov, V. V., Fradkov, A. F., Lukyanov, K. A., Staroverov, D. B., Shakhbazov, K., Terskikh, A. V., & Lukyanov, S. (2006) · Nature Methods · doi:10.1038/nmeth866 · Cited by 1,260 · see citing works

Measurement of Mitochondrial Membrane Potential Using Fluorescent Rhodamine Derivatives

Scaduto, R. C., & Grotyohann, L. W. (1999) · Biophysical Journal · doi:10.1016/s0006-3495(99)77214-0 · Cited by 1,232 · see citing works

Oxidative Stress in the Pathogenesis of Skin Disease

Bickers, D. R., & Athar, M. (2006) · Journal of Investigative Dermatology · doi:10.1038/sj.jid.5700340 · Cited by 1,092 · see citing works

UV-induced skin damage

Ichihashi, M., Ueda, M., Budiyanto, A., Bito, T., Oka, M., Fukunaga, M., Tsuru, K., & Horikawa, T. (2003) · Toxicology · doi:10.1016/s0300-483x(03)00150-1 · Cited by 970 · see citing works

Cytochrome c release from mitochondria proceeds by a two-step process

Ott, M., Robertson, J. D., Gogvadze, V. G., Zhivotovsky, B., & Orrenius, S. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.241655498 · Cited by 955 · see citing works

Intracellular messenger function of hydrogen peroxide and its regulation by peroxiredoxins

Rhee, S. G., Kang, S. W., Jeong, W., Chang, T.-S., Yang, K., & Woo, H. A. (2005) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2005.02.004 · Cited by 709 · see citing works

Peroxiredoxins: guardians against oxidative stress and modulators of peroxide signaling

Perkins, A., Nelson, K. J., Parsonage, D., Poole, L. B., & Karplus, P. A. (2015) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2015.05.001 · Cited by 648 · see citing works

Mitochondrial peroxiredoxin involvement in antioxidant defence and redox signalling

Cox, A. G., Winterbourn, C. C., & Hampton, M. B. (2009) · Biochemical Journal · doi:10.1042/bj20091541 · Cited by 530 · see citing works

A Palette of Fluorescent Probes with Varying Emission Colors for Imaging Hydrogen Peroxide Signaling in Living Cells

Dickinson, B. C., Huynh, C., & Chang, C. J. (2010) · Journal of the American Chemical Society · doi:10.1021/ja1014103 · Cited by 513 · see citing works

Mitochondrial oxidative stress causes mitochondrial fragmentation via differential modulation of mitochondrial fission–fusion proteins

Wu, S., Zhou, F., Zhang, Z., & Xing, D. (2011) · FEBS Journal · doi:10.1111/j.1742-4658.2011.08010.x · Cited by 420 · see citing works

Mechanisms of Photoaging and Cutaneous Photocarcinogenesis, and Photoprotective Strategies with Phytochemicals

Bosch, R., Philips, N., Suárez-Pérez, J., Juarranz, A., Devmurari, A., Chalensouk-Khaosaat, J., & González, S. (2015) · Antioxidants · doi:10.3390/antiox4020248 · Cited by 407 · see citing works

Peroxiredoxin III, a Mitochondrion-specific Peroxidase, Regulates Apoptotic Signaling by Mitochondria

Chang, T.-S., Cho, C.-S., Park, S., Yu, S., Kang, S. W., & Rhee, S. G. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m407707200 · Cited by 388 · see citing works

Mitochondrial phospholipid hydroperoxide glutathione peroxidase inhibits the release of cytochrome c from mitochondria by suppressing the peroxidation of cardiolipin in hypoglycaemia-induced apoptosis

Nomura, K., Imai, H., Koumura, T., Kobayashi, T., & Nakagawa, Y. (2000) · Biochemical Journal · doi:10.1042/0264-6021:3510183 · Cited by 373 · see citing works

UVB Light Stimulates Production of Reactive Oxygen Species

Heck, D. E., Vetrano, A. M., Mariano, T. M., & Laskin, J. D. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.c300048200 · Cited by 370 · see citing works

10N‐Nonyl acridine orange interacts with cardiolipin and allows the quantification of this phospholipid in isolated mitochondria

Petit, J., Maftah, A. A., Ratinaud, M., & Julien, R. (1992) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1992.tb17285.x · Cited by 334 · see citing works

Oxidative stress in malignant melanoma and non-melanoma skin cancer

Sander, C. S., Hamm, F., Elsner, P. U., & Thiele, J. J. (2003) · British Journal of Dermatology · doi:10.1046/j.1365-2133.2003.05303.x · Cited by 300 · see citing works

The Role of Antioxidants in Skin Cancer Prevention and Treatment

Godic, A., Poljšak, B., Adamic, M., & Dahmane, R. (2014) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2014/860479 · Cited by 293 · see citing works

Overexpression of Mitochondrial Peroxiredoxin-3 Prevents Left Ventricular Remodeling and Failure After Myocardial Infarction in Mice

Matsushima, S., Ide, T., Yamato, M., Matsusaka, H., Hattori, F., Ikeuchi, M., Kubota, T., Sunagawa, K., Hasegawa, Y., Kurihara, T., et al. (2006) · Circulation · doi:10.1161/circulationaha.105.582239 · Cited by 262 · see citing works

Photocarcinogenesis: an overview

Black, H. S., deGruijl, F. R., Forbes, P. D., Cleaver, J. E., Ananthaswamy, H. N., DeFabo, E. C., Ullrich, S. E., & Tyrrell, R. M. (1997) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/s1011-1344(97)00021-3 · Cited by 258 · see citing works

Mitochondrial phospholipid hydroperoxide glutathione peroxidase inhibits the release of cytochrome c from mitochondria by suppressing the peroxidation of cardiolipin in hypoglycaemia-induced apoptosis

Nomura, K., Imai, H., Koumura, T., et al. (2000) · Biochemical Journal · doi:10.1042/bj3510183 · Cited by 255 · see citing works

Loss of Molecular Interaction between Cytochrome c and Cardiolipin Due to Lipid Peroxidation

Shidoji, Y., Hayashi, K., KOMURA, S., Ohishi, N., & Yagi, K. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.1410 · Cited by 250 · see citing works

Mechanisms of photodamage of the skin and its functional consequences for skin ageing

Trautinger, F. (2001) · Clinical and Experimental Dermatology · doi:10.1046/j.1365-2230.2001.00893.x · Cited by 210 · see citing works

Feedback Control of Adrenal Steroidogenesis via H2O2-Dependent, Reversible Inactivation of Peroxiredoxin III in Mitochondria

Kil, I. S., Lee, S. K., Ryu, K. W., Woo, H. A., Hu, M., Bae, S. H., & Rhee, S. G. (2012) · Molecular Cell · doi:10.1016/j.molcel.2012.05.030 · Cited by 184 · see citing works

Nrf2 establishes a glutathione-mediated gradient of UVB cytoprotection in the epidermis

Schäfer, M., Dütsch, S., auf dem Keller, U., Navid, F., Schwarz, A., Johnson, D. A., Johnson, J. A., & Werner, S. (2010) · Genes & Development · doi:10.1101/gad.568810 · Cited by 175 · see citing works

TheGpx1Gene Encodes Mitochondrial Glutathione Peroxidase in the Mouse Liver

Esworthy, R. S., Ho, Y., & Chu, F. (1997) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1997.9901 · Cited by 165 · see citing works

Preparation and use of MitoPY1 for imaging hydrogen peroxide in mitochondria of live cells

Dickinson, B. C., Lin, V., & Chang, C. J. (2013) · Nature Protocols · doi:10.1038/nprot.2013.064 · Cited by 163 · see citing works

Peroxiredoxin 3 Is a Key Molecule Regulating Adipocyte Oxidative Stress, Mitochondrial Biogenesis, and Adipokine Expression

Huh, J. Y., Kim, Y., Jeong, J., Park, J., Kim, I., Huh, K. H., Kim, Y. S., Woo, H. A., Rhee, S. G., Lee, K., et al. (2011) · Antioxidants and Redox Signaling · doi:10.1089/ars.2010.3766 · Cited by 157 · see citing works

Involvement of UVB-induced reactive oxygen species in TGF-β biosynthesis and activation in keratinocytes

Wang, H., & Kochevar, I. E. (2004) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2004.12.005 · Cited by 139 · see citing works

A primer on peroxiredoxin biochemistry

Karplus, P. A. (2014) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2014.10.009 · Cited by 131 · see citing works

Import into Mitochondria of Phospholipid Hydroperoxide Glutathione Peroxidase Requires a Leader Sequence

Arai, M., Imai, H., Sumi, D., Imanaka, T., Takano, T., Chiba, N., & Nakagawa, Y. (1996) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1996.1525 · Cited by 129 · see citing works

Role of mitochondria in ultraviolet-induced oxidative stress

Gniadecki, R., Thorn, T., Vičanová, J., Petersen, A., & Wulf, H. C. (2000) · Journal of Cellular Biochemistry · doi:10.1002/1097-4644(20010201)80:2 · Cited by 121 · see citing works

Protective Effects of Catalase Overexpression on UVB-induced Apoptosis in Normal Human Keratinocytes

Rezvani, H. R., Mazurier, F., Cario, M., Pain, C., Ged, C., Taı̈eb, A., & de Verneuil, H. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m600536200 · Cited by 120 · see citing works

Hypoxia-inducible Factor-1α, a Key Factor in the Keratinocyte Response to UVB Exposure

Rezvani, H. R., Dedieu, S., North, S., Belloc, F., Rossignol, R., Letellier, T., de Verneuil, H., Taı̈eb, A., & Mazurier, F. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m611397200 · Cited by 97 · see citing works

Apoptosis signal regulating kinase-1 connects reactive oxygen species to p38 MAPK-induced mitochondrial apoptosis in UVB-irradiated human keratinocytes

Laethem, A. V., Nys, K., Kelst, S. V., Claerhout, S., Ichijo, H., Vandenheede, J. R., Garmyn, M., & Agostinis, P. (2006) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2006.07.007 · Cited by 87 · see citing works

High levels of 8-hydroxy-2′-deoxyguanosine appear in normal human epidermis after a single dose of ultraviolet radiation

AHMED, N. U., UEDA, M., Nikaido, O., Osawa, T., & Ichihashi, M. (1999) · British Journal of Dermatology · doi:10.1111/j.1365-2133.1999.02653.x · Cited by 75 · see citing works

A role for human mitochondrial complex II in the production of reactive oxygen species in human skin

Anderson, A., Bowman, A., Boulton, S. J., Manning, P., & Birch-Machin, M. A. (2014) · Redox Biology · doi:10.1016/j.redox.2014.08.005 · Cited by 65 · see citing works

Mytoe: automatic analysis of mitochondrial dynamics

Lihavainen, E., Mäkelä, J., Spelbrink, J. N., & Ribeiro, A. S. (2012) · Bioinformatics · doi:10.1093/bioinformatics/bts073 · Cited by 64 · see citing works

UVB Radiation Induces Apoptosis in Keratinocytes by Activating a Pathway Linked to “BLT2-Reactive Oxygen Species”

Ryu, H.-C., Kim, C.-M., Kim, J., Chung, J., & Kim, J. (2010) · Journal of Investigative Dermatology · doi:10.1038/jid.2009.436 · Cited by 62 · see citing works

An improved method for culture of epidermal keratinocytes from newborn mouse skin

Häkkinen, L., Koivisto, L., & Larjava, H. (2001) · Methods in Cell Science · doi:10.1023/a:1016385109922 · Cited by 60 · see citing works

Quantification and Characterization of UVB-Induced Mitochondrial Fragmentation in Normal Primary Human Keratinocytes

Jugé, R., Breugnot, J., Silva, C. D., Bordes, S., Closs, B., & Aouacheria, A. (2016) · Scientific Reports · doi:10.1038/srep35065 · Cited by 60 · see citing works

Peroxiredoxin III protects pancreatic ß cells from apoptosis.

Wolf, G., Aumann, N., Michalska, M., Bast, A., Sonnemann, J., Beck, J., Lendeckel, U., Newsholme, P., & Walther, R. (2010) · Journal of Endocrinology · doi:10.1677/joe-09-0455 · Cited by 58 · see citing works

Mitochondrial H2O2 signaling is controlled by the concerted action of peroxiredoxin III and sulfiredoxin: Linking mitochondrial function to circadian rhythm

Rhee, S. G., & Kil, I. S. (2016) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2016.10.011 · Cited by 57 · see citing works

Protective Role of Copper, Zinc Superoxide Dismutase Against UVB-Induced Injury of the Human Keratinocyte Cell Line HaCaT

Sasaki, H., Akamatsu, H., & Horio, T. (2000) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2000.00914.x · Cited by 54 · see citing works

Differential role of hydrogen peroxide in UV-induced signal transduction

Ding, M., Lia, J., Leonard, S. S., Shi, X., Costa, M., Castranova, V., Vallyathan, V., & Huang, C. (2002) · Molecular and Cellular Biochemistry · doi:10.1023/a:1015901232124 · Cited by 51 · see citing works

Peroxiredoxin III and Sulfiredoxin Together Protect Mice from Pyrazole-Induced Oxidative Liver Injury

Bae, S. H., Sung, S. H., Lee, H., Kang, H. T., Lee, S. K., Oh, S. Y., Woo, H. A., Kil, I. S., & Rhee, S. G. (2012) · Antioxidants and Redox Signaling · doi:10.1089/ars.2011.4334 · Cited by 50 · see citing works

Starting and propagating apoptotic signals in UVB irradiated keratinocytes

Laethem, A. V., Garmyn, M., & Agostinis, P. (2009) · Photochemical & Photobiological Sciences · doi:10.1039/b813346h · Cited by 49 · see citing works

Peroxiredoxin is Ubiquitously Expressed in Rat Skin: Isotype-Specific Expression in the Epidermis and Hair Follicle

Lee, J. E., Kwon, B. D., Lee, J.-B., Won, Y., Kim, Y. P., Lee, S., Chae, H. Z., & Ahn, K. Y. (2000) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2000.00177.x · Cited by 31 · see citing works

Mitochondrial H2O2 signaling is controlled by the concerted action of peroxiredoxin III and sulfiredoxin: Linking mitochondrial function to circadian rhythm

Rhee, S. G., & Kil, I. S. (2016) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2016.07.029 · Cited by 22 · see citing works

Studies on the nature of superoxide dismutase activity in sheep liver subcellular fractions.

Konstantinova, S. G., & Russanov, E. (1988) · PubMed · Cited by 5 · see citing works

113 Immortalized N/TERT keratinocytes: An excellent and versatile alternative for primary keratinocytes in experimental dermatological research

Smits, J. G. A., Niehues, H., Rikken, G., et al. (2017) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2017.07.423 · Cited by 2 · see citing works

Effect of Yinxieling Prescription and Its Modified Prescriptions on Keratinocyte HaCaT Proliferation

Lu, C. (2011) · Guangzhou Zhongyiyao Daxue xuebao · Cited by 1 · see citing works

Wound healing promoting activity of Earthworm, Eutyphoeus gammiei (Beddard): in vitro studies on human skin keratinocyte cell line (HaCat).

Saha, S., Bhattacharjee, D., Saha, A., et al. (2018) · Journal of Drug Delivery and Therapeutics · doi:10.22270/jddt.v8i6.2036 · Cited by 1 · see citing works

Screening of Xerosis Inhibitor from Seaweed Extracts Using HaCaT Keratinocyte

Yoon, S.-J., Khan, M. N. A., Kang, J.-Y., et al. (2010) · Han-gug hae-yang ba-i-o haghoeji/Han-guk haeyang baio hakoeji

Expression and function of connexin in normal and transformed human keratinocytes in culture

Fitzgerald, D. J., Fusenig, N. E., Boukamp, P., et al. (1994) · Carcinogenesis · doi:10.1093/carcin/15.9.1859 · Cited by 47 · see citing works