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ASCL1- and DLX2-induced GABAergic neurons from hiPSC-derived NPCs
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“Disease-agnostic analyses reveal that transcription factors and nucleic acid binding proteins are overwhelmingly driven by LOF mutations, whereas signaling molecules, enzymes, receptors and transporters more frequently incur dominant GOF mutations55.”
From Phenotypic complexities of rare heterozygous neurexin-1 deletions (2025) · cites this paper as [55]
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Lim, L., Mi, D., Llorca, A., & Marín, O. (2018) · Neuron · doi:10.1016/j.neuron.2018.10.009 · Cited by 714 · cited 1×
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Cited by
Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants
Zhang, S., Zhang, H., Zhou, Y., Qiao, M., Zhao, S., Kozlova, A., Shi, J., Sanders, A. R., Wang, G., Luo, K., et al. (2020) · Science · doi:10.1126/science.aay3983 · Cited by 127
Self-citationPhenotypic complexities of rare heterozygous neurexin-1 deletions
Fernando, M. B., Fan, Y., Zhang, Y., Tokolyi, A., Murphy, A. N., Kammourh, S., Deans, P. J. M., Ghorbani, S., Onatzevitch, R., Pero, A., et al. (2025) · Nature · doi:10.1038/s41586-025-08864-9 · Cited by 30
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Metadata
- Authors
- Barretto, N., Zhang, H., Powell, S. K., Fernando, M. B., Zhang, S., Flaherty, E. K., Ho, S.-M., Slesinger, P. A., Duan, J., & Brennand, K. J.
- Venue
- Journal of Neuroscience Methods
- Publisher
- Elsevier BV
- Published
- 2020-03
- Volume
- 334
- Pages
- 108548
- ISSN
- 0165-0270
- PMC
- PMC7426253
- Cited by
- 45
- References
- 4
- Language
- en
- Funders
- National Institute of Mental Health
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- Barretto, N., Zhang, H., Powell, S. K., Fernando, M. B., Zhang, S., Flaherty, E. K., Ho, S.-M., Slesinger, P. A., Duan, J., & Brennand, K. J. (2020). ASCL1- and DLX2-induced GABAergic neurons from hiPSC-derived NPCs. Journal of Neuroscience Methods. https://doi.org/10.1016/j.jneumeth.2019.108548
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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
