Cited by 423Psychometric Methodologies and TestingAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesMental Health Research Topics

Validation of the depression item bank from the Patient-Reported Outcomes Measurement Information System (PROMIS) in a three-month observational study

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Pilkonis, Paul A., Yu, Lan, Dodds, Nathan E., Johnston, Kelly L., Maihoefer, Catherine C., Lawrence, Suzanne M.·2014·Journal of Psychiatric Research

Abstract

The Patient-Reported Outcomes Measurement Information System (PROMIS) is an NIH Roadmap initiative devoted to developing better measurement tools for assessing constructs relevant to the clinical investigation and treatment of all diseases-constructs such as pain, fatigue, emotional distress, sleep, physical functioning, and social participation. Following creation of item banks for these constructs, our priority has been to validate them, most often in short-term observational studies. We report here on a three-month prospective observational study with depressed outpatients in the early stages of a new treatment episode (with assessments at intake, one-month follow-up, and three-month follow-up). The protocol was designed to compare the psychometric properties of the PROMIS depression item bank (administered as a computerized adaptive test, CAT) with two legacy self-report instruments: the Center for Epidemiological Studies Depression scale (CESD; Radloff, 1977) and the Patient Health Questionnaire (PHQ-9; Spitzer et al., 1999). PROMIS depression demonstrated strong convergent validity with the CESD and the PHQ-9 (with correlations in a range from .72 to .84 across all time points), as well as responsiveness to change when characterizing symptom severity in a clinical outpatient sample. Identification of patients as "recovered" varied across the measures, with the PHQ-9 being the most conservative. The use of calibrations based on models from item response theory (IRT) provides advantages for PROMIS depression both psychometrically (creating the possibility of adaptive testing, providing a broader effective range of measurement, and generating greater precision) and practically (these psychometric advantages can be achieved with fewer items-a median of 4 items administered by CAT-resulting in less patient burden).

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  • The PROMIS depression scale has strong evidence of construct validity, having been validated against the CES-D, BDI-II, and PHQ-9.

    “There is strong evidence of construct validity for the PROMIS depression scale, which has been validated against the Center for Epidemiological Studies Depression Scale (CES-D), the Beck Depression Inventory (BDI-II), and the Patient Health Questionnaire (PHQ-9) (Choi et al., 2014; Pilkonis et al., 2014).”

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Research works printed but not linked: 2

  1. Choi SW Podrabsky T McKinney N Schalet BD Cook K Cella D PROSetta® Stone Analysis Report: a Rosetta Stone for Patient Reported Outcomes (Vol. 1) 2012 Chicago, IL Department of Medical Social Sciences, Feinberg School of Medicine, Northwestern University
  2. World Health Organization Constitution of the World Health Organization: Basic documents (46th ed.) 2007 Geneva Author

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Authors
Pilkonis, P. A., Yu, L., Dodds, N. E., Johnston, K. L., Maihoefer, C. C., & Lawrence, S. M.
Affiliations
University of Pittsburgh (US)
Corresponding author
Pilkonis, Paul A.
Venue
Journal of Psychiatric Research
Publisher
Elsevier BV
Published
2014-09
Volume
56
Pages
112-119
ISSN
0022-3956 (ISSN-L)
OpenAlex
W1976407136
Cited by
423
References
23
Citations by year
2026: 42 · 2025: 48 · 2024: 52 · 2023: 64 · 2022: 63 · 2021: 41 · 2020: 35 · 2019: 22 · 2018: 23 · 2017: 11 · 2016: 13 · 2015: 8 · 2014: 1
FWCI
13.82
Type
journal article
Language
en
Open access
Locations
  • Journal of Psychiatric Research (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institutes of Health (5u01ar057940-04)
  • National Institute of Arthritis and Musculoskeletal and Skin Diseases (U01AR052171, U01AR057956, U01AR057967, U01AR052186, U01-AR-057940, U01AR057936, U54AR057943, U01AR057929, U01AR052170, U01AR052158, U01AR052155, U01AR052177, U01AR052181, U01AR057954, U01AR057948, U54AR057926, U54AR057951)
Topics
  • Social Sciences › Decision Sciences › Management Science and Operations Research › Psychometric Methodologies and Testing
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
Keywords
depression measurement, computerized adaptive testing, convergent validity, responsiveness to change, CES-D, PHQ-9, symptom severity, recovery from depression, patient-reported outcomes, outpatients
MeSH terms
Adolescent, Adult, Aged, Aged, 80 and over, Calibration, Computers, Depressive Disorder, Female, Follow-Up Studies, Humans, Male, Middle Aged, Outpatients, Prospective Studies, Psychometrics, Young Adult, Self Report, Patient Outcome Assessment

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