Pseudomalabsorption de L-thyroxine: une forme de pathomimie
Abstract
Introduction Thyroxine supplementation of patients with hypothyroidism is usually simple. A few patients, however, continue to present elevated TSH levels despite large doses of L-thyroxine.Case We report the case of a 71-year-old women who had had a thyroidectomy 10 years earlier and had since been hospitalized repeatedly for profound hypothyroidism. Despite her consistent claims of good adherence to her treatment regimen, we considered the diagnosis of L-thyroxine pseudomalabsorption and confirmed it by thyroid hormone absorption tests.Discussion L-thyroxine pseudomalabsorption due to concealed poor treatment adherence should be considered after ruling out drug or dietary interference and true organic malabsorption. Diagnosis of this factitious disease can be confirmed by L-thyroxine absorption tests.
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A completely normal result in the LT4 absorption test in individuals suspected of having malabsorption is strongly suggestive of pseudomalabsorption.
“A completely normal result in the LT4 absorption test in individuals suspected of having malabsorption is strongly suggestive of pseudomalabsorption (130).”
From Levothyroxine: conventional and novel drug delivery formulations. (2023) · cites this paper as [130]
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- Authors
- Molines, L., Fromont, I., Morlet-Barla, N., Nogueira, J.-P., Valéro, R., & Vialettes, B.
- Affiliations
- Hôpital de la Timone (FR)
- Corresponding author
- Molines, Laurent
- Venue
- La Presse Médicale
- Publisher
- Elsevier BV
- Published
- 2007-10
- Volume
- 36
- Issue
- 10
- Pages
- 1390-1394
- ISSN
- 0032-7867 (ISSN-L)
- 0755-4982
- OpenAlex
- W2084002483
- Cited by
- 10
- References
- 45
- Citations by year
- 2023: 1 · 2022: 1 · 2018: 1 · 2017: 1 · 2016: 1 · 2014: 2 · 2013: 1 · 2012: 1
- FWCI
- 0.24
- Type
- journal article
- Language
- fr
- Open access
- closed
- Locations
- La Presse Médicale (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Keywords
- hypothyroidism, thyroxine replacement, treatment non-adherence, TSH elevation, factitious disorder, thyroidectomy
- MeSH terms
- Aged, Diagnosis, Differential, Factitious Disorders, Female, Goiter, Nodular, Humans, Hypothyroidism, Intestinal Absorption, Malabsorption Syndromes, Patient Compliance, Thyroidectomy, Thyroxine, Time Factors
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