The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Life-long endurance exercise in humans: circulating levels of inflammatory markers and leg muscle size.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“This is in line with two studies (Mikkelsen et al., 2013; Couppe et al., 2014) that reported greater muscle size of Masters endurance athletes than age-matched controls.”
From Comparison of Muscle Function, Bone Mineral Density and Body Composition of Early Starting and Later Starting Older Masters Athletes (2019) · cites this paper as Mikkelsen et al., 2013
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
2011 Compendium of Physical Activities: A Second Update of Codes and MET Values
AINSWORTH, B. E., HASKELL, W. L., HERRMANN, S. D., MECKES, N., BASSETT, D. R., TUDOR-LOCKE, C., GREER, J. L., VEZINA, J., WHITT-GLOVER, M. C., & LEON, A. S. (2011) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e31821ece12 · Cited by 6,317
Visser, M., Pahor, M., Taaffe, D. R., Goodpaster, B. H., Simonsick, E. M., Newman, A. B., Nevitt, M., & Harris, T. B. (2002) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/57.5.m326 · Cited by 1,294
C Reactive Protein Coronary Heart Disease Genetics Collaboration (CCGC) (2011) · BMJ · doi:10.1136/bmj.d548 · Cited by 642
Association between Physical Activity and Markers of Inflammation in a Healthy Elderly Population
Geffken, D. F., Cushman, M., Burke, G. L., Polak, J. F., Sakkinen, P. A., & Tracy, R. P. (2001) · American Journal of Epidemiology · doi:10.1093/aje/153.3.242 · Cited by 599
Taaffe, D. R., Harris, T. B., Ferrucci, L., Rowe, J., & Seeman, T. E. (2000) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/55.12.m709 · Cited by 438 · cited 3×
“…markers of inflammation: higher levels of physical activity are coupled to lower levels of circulating inflammatory markers in elderly individuals (Taaffe et al., 2000; Geffken et al., 2001; Wannamethee et al., 2002; Reuben et al., 2003; Colbert et al., 2004; Albert et al., 2004; Rahimi et al.,…”
BackgroundKohut, M. L., McCann, D. A., Russell, D. W., Konopka, D. N., Cunnick, J. E., Franke, W. D., Castillo, M. C., Reighard, A. E., & Vanderah, E. (2006) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2005.12.002 · Cited by 436
Ryanodine receptor oxidation causes intracellular calcium leak and muscle weakness in aging
Andersson, D. C., Betzenhauser, M. J., Reiken, S., Meli, A. C., Umanskaya, A., Xie, W., Shiomi, T., Zalk, R., Lacampagne, A., & Marks, A. R. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.05.014 · Cited by 424
Tanaka, H., & Seals, D. R. (2003) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00320.2003 · Cited by 275
Nicklas, B. J. (2005) · Canadian Medical Association Journal · doi:10.1503/cmaj.1040769 · Cited by 259
Glucose tolerance in young and older athletes and sedentary men
Seals, D. R., Hagberg, J. M., Allen, W. K., Hurley, B. F., Dalsky, G. P., Ehsani, A. A., & Holloszy, J. O. (1984) · Journal of Applied Physiology · doi:10.1152/jappl.1984.56.6.1521 · Cited by 228
Research works printed but not linked: 55
- Allin, 2010, C-reactive protein and the risk of cancer: a mendelian randomization study, J. Natl. Cancer Inst., 102, 202, 10.1093/jnci/djp459 · DOI
- Bruunsgaard, 1999, A high plasma concentration of TNF-alpha is associated with dementia in centenarians, J. Gerontol. A. Biol. Sci. Med. Sci., 54, M357, 10.1093/gerona/54.7.M357 · DOI · Paper page
- Bruunsgaard, 2000, Ageing, tumour necrosis factor-alpha (TNF-alpha) and atherosclerosis, Clin. Exp. Immunol., 121, 255, 10.1046/j.1365-2249.2000.01281.x · DOI · Paper page
- Burks, 2011, Losartan restores skeletal muscle remodeling and protects against disuse atrophy in sarcopenia, Sci. Transl. Med., 3, 10.1126/scitranslmed.3002227 · DOI
- Campbell, 2009, A yearlong exercise intervention decreases CRP among obese postmenopausal women, Med. Sci. Sports Exerc., 41, 1533, 10.1249/MSS.0b013e31819c7feb · DOI
- Colbert, 2004, Physical activity, exercise, and inflammatory markers in older adults: findings from the Health, Aging and Body Composition Study, J. Am. Geriatr. Soc., 52, 1098, 10.1111/j.1532-5415.2004.52307.x · DOI · Paper page
- Cordova, 2011, Long-term resistance training is associated with reduced circulating levels of IL-6, IFN-gamma and TNF-alpha in elderly women, Neuroimmunomodulation, 18, 165, 10.1159/000323396 · DOI
- Craig, 2003, International physical activity questionnaire: 12-country reliability and validity, Med. Sci. Sports Exerc., 35, 1381, 10.1249/01.MSS.0000078924.61453.FB · DOI · Paper page
- Donato, 2008, Aging is associated with greater nuclear NF kappa B, reduced I kappa B alpha, and increased expression of proinflammatory cytokines in vascular endothelial cells of healthy humans, Aging Cell, 7, 805, 10.1111/j.1474-9726.2008.00438.x · DOI · Paper page
- Dunn, 1979, Further development and automation of a high pressure liquid chromatography method for the determination of glycosylated hemoglobins, Metabolism, 28, 777, 10.1016/0026-0495(79)90185-9 · DOI
- Elosua, 2005, Association between physical activity, physical performance, and inflammatory biomarkers in an elderly population: the InCHIANTI study, J. Gerontol. A. Biol. Sci. Med. Sci., 60, 760, 10.1093/gerona/60.6.760 · DOI · Paper page
- Eugen-Olsen, 2010, Circulating soluble urokinase plasminogen activator receptor predicts cancer, cardiovascular disease, diabetes and mortality in the general population, J. Intern. Med., 268, 296, 10.1111/j.1365-2796.2010.02252.x · DOI · Paper page
- Faulkner, 2008, The aging of elite male athletes: age-related changes in performance and skeletal muscle structure and function, Clin. J. Sport Med., 18, 501, 10.1097/JSM.0b013e3181845f1c · DOI
- Fried, 2001, Frailty in older adults: evidence for a phenotype, J. Gerontol. A. Biol. Sci. Med. Sci., 56, M146, 10.1093/gerona/56.3.M146 · DOI · Paper page
- Galloway, 2002, Effect of aging on male and female master athletes’ performance in strength versus endurance activities, Am. J. Orthop. (Belle Mead, NJ), 31, 93
- Hagberg, 1998, Expanded blood volumes contribute to the increased cardiovascular performance of endurance-trained older men, J. Appl. Physiol., 85, 484, 10.1152/jappl.1998.85.2.484 · DOI
- Hammett, 2004, Effect of six months’ exercise training on C-reactive protein levels in healthy elderly subjects, J. Am. Coll. Cardiol., 44, 2411, 10.1016/j.jacc.2004.09.030 · DOI
- Harris, 1999, Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly, Am. J. Med., 106, 506, 10.1016/S0002-9343(99)00066-2 · DOI · Paper page
- Hawkins, 2001, A longitudinal assessment of change in VO2max and maximal heart rate in master athletes, Med. Sci. Sports Exerc., 33, 1744, 10.1097/00005768-200110000-00020 · DOI · Paper page
- Henriksson, 1995, Influence of exercise on insulin sensitivity, J. Cardiovasc. Risk, 2, 303, 10.1097/00043798-199508000-00004 · DOI
- Langkilde, 2011, Increased plasma soluble uPAR level is a risk marker of respiratory cancer in initially cancer-free individuals, Cancer Epidemiol. Biomarkers Prev., 20, 609, 10.1158/1055-9965.EPI-10-1009 · DOI
- Leon, 2001, Response of blood lipids to exercise training alone or combined with dietary intervention, Med. Sci. Sports Exerc., 33, S502, 10.1097/00005768-200106001-00021 · DOI · Paper page
- Li, 2001, Effect of tumor necrosis factor-alpha on skeletal muscle metabolism, Curr. Opin. Rheumatol., 13, 483, 10.1097/00002281-200111000-00005 · DOI
- Lund, 2011, Markers of chronic inflammation with short-term changes in physical activity, Med. Sci. Sports Exerc., 43, 578, 10.1249/MSS.0b013e3181f59dc4 · DOI
- Lutz, 2012, Sarcopenia, obesity, and natural killer cell immune senescence in aging: altered cytokine levels as a common mechanism, Aging (Albany, NY), 4, 535, 10.18632/aging.100482 · DOI · Paper page
- Lyngbaek, 2013, Cardiovascular risk prediction in the general population with use of suPAR, CRP, and Framingham Risk Score, Int. J. Cardiol., 167, 2904, 10.1016/j.ijcard.2012.07.018 · DOI
- Lyngbaek, 2013, CRP and suPAR are differently related to anthropometry and subclinical organ damage, Int. J. Cardiol., 167, 781, 10.1016/j.ijcard.2012.03.040 · DOI
- Mariani, 2006, Simultaneous evaluation of circulating chemokine and cytokine profiles in elderly subjects by multiplex technology: relationship with zinc status, Biogerontology, 7, 449, 10.1007/s10522-006-9060-8 · DOI
- Mosca, 1986, Automated determination of glycated hemoglobins with a new high-performance liquid chromatography analyzer, Clin. Chem., 32, 202, 10.1093/clinchem/32.1.202 · DOI
- Narici, 2010, Sarcopenia: characteristics, mechanisms and functional significance, Br. Med. Bull., 95, 139, 10.1093/bmb/ldq008 · DOI · Paper page
- Nicklas, 2008, Exercise training and plasma C-reactive protein and interleukin-6 in elderly people, J. Am. Geriatr. Soc., 56, 2045, 10.1111/j.1532-5415.2008.01994.x · DOI · Paper page
- Nordin, 2004, A multicentre study of reference intervals for haemoglobin, basic blood cell counts and erythrocyte indices in the adult population of the Nordic countries, Scand. J. Clin. Lab. Invest., 64, 385, 10.1080/00365510410002797 · DOI
- Ogawa, 2010, Resistance exercise training-induced muscle hypertrophy was associated with reduction of inflammatory markers in elderly women, Mediators Inflamm., 2010, 171023, 10.1155/2010/171023 · DOI
- Onambele-Pearson, 2010, Influence of exercise intensity in older persons with unchanged habitual nutritional intake: skeletal muscle and endocrine adaptations, Age (Dordr.), 32, 139, 10.1007/s11357-010-9141-0 · DOI
- Park, 2005, Relationship of obesity and visceral adiposity with serum concentrations of CRP, TNF-alpha and IL-6, Diabetes Res. Clin. Pract., 69, 29, 10.1016/j.diabres.2004.11.007 · DOI · Paper page
- Phillips, 2012, Resistance training reduces subclinical inflammation in obese, postmenopausal women, Med. Sci. Sports Exerc., 44, 2099, 10.1249/MSS.0b013e3182644984 · DOI
- Rahimi, 2005, Correlation of exercise capacity with high-sensitive C-reactive protein in patients with stable coronary artery disease, Am. Heart J., 150, 1282, 10.1016/j.ahj.2005.01.006 · DOI
- Rogers, 1990, Decline in VO2max with aging in master athletes and sedentary men, J. Appl. Physiol., 68, 2195, 10.1152/jappl.1990.68.5.2195 · DOI · Paper page
- Roubenoff, 2007, Physical activity, inflammation, and muscle loss, Nutr. Rev., 65, S208, 10.1301/nr.2007.dec.S208-S212 · DOI
- Ryan, 2000, Insulin resistance with aging: effects of diet and exercise, Sports Med., 30, 327, 10.2165/00007256-200030050-00002 · DOI · Paper page
- Sanchis-Gomar, 2013, Effects of acute exercise and allopurinol administration on soluble urokinase plasminogen activator receptor (suPAR), Clin. Lab., 59, 207, 10.7754/Clin.Lab.2012.120728 · DOI
- Schaap, 2009, Higher inflammatory marker levels in older persons: associations with 5-year change in muscle mass and muscle strength, J. Gerontol. A. Biol. Sci. Med. Sci., 64, 1183, 10.1093/gerona/glp097 · DOI · Paper page
- Schaap, 2006, Inflammatory markers and loss of muscle mass (sarcopenia) and strength, Am. J. Med., 119, 526, 10.1016/j.amjmed.2005.10.049 · DOI · Paper page
- Sennels, 2012, Rhythmic 24-hour variations of frequently used clinical biochemical parameters in healthy young males--the Bispebjerg study of diurnal variations, Scand. J. Clin. Lab. Invest., 72, 287, 10.3109/00365513.2012.662281 · DOI
- Sennels, 2011, Diurnal variation of hematology parameters in healthy young males: the Bispebjerg study of diurnal variations, Scand. J. Clin. Lab. Invest., 71, 532, 10.3109/00365513.2011.602422 · DOI
- Stowe, 2010, Plasma cytokine levels in a population-based study: relation to age and ethnicity, J. Gerontol. A. Biol. Sci. Med. Sci., 65, 429, 10.1093/gerona/glp198 · DOI
- Tarpenning, 2004, Endurance training delays age of decline in leg strength and muscle morphology, Med. Sci. Sports Exerc., 36, 74, 10.1249/01.MSS.0000106179.73735.A6 · DOI
- Toth, 2006, Immune activation is associated with reduced skeletal muscle mass and physical function in chronic heart failure, Int. J. Cardiol., 109, 179, 10.1016/j.ijcard.2005.06.006 · DOI
- Valentine, 2009, Stronger relationship between central adiposity and C-reactive protein in older women than men, Menopause, 16, 84, 10.1097/gme.0b013e31817fcb8f · DOI
- Vieira, 2009, Reduction in trunk fat predicts cardiovascular exercise training-related reductions in C-reactive protein, Brain Behav. Immun., 23, 485, 10.1016/j.bbi.2009.01.011 · DOI
- Vogel, 2009, Health benefits of physical activity in older patients: a review, Int. J. Clin. Pract., 63, 303, 10.1111/j.1742-1241.2008.01957.x · DOI · Paper page
- Wannamethee, 2002, Physical activity and hemostatic and inflammatory variables in elderly men, Circulation, 105, 1785, 10.1161/hc1502.107117 · DOI
- Wiswell, 2001, Relationship between physiological loss, performance decrement, and age in master athletes, J. Gerontol. A. Biol. Sci. Med. Sci., 56, M618, 10.1093/gerona/56.10.M618 · DOI · Paper page
- Yataco, 1997, Relationship of body composition and cardiovascular fitness to lipoprotein lipid profiles in master athletes and sedentary men, Aging (Milano), 9, 88
- Yu, 2009, Associations of physical activity with inflammatory factors, adipocytokines, and metabolic syndrome in middle-aged and older chinese people, Circulation, 119, 2969, 10.1161/CIRCULATIONAHA.108.833574 · DOI
Cited by
Exercise Attenuates the Major Hallmarks of Aging
Garatachea, N., Pareja-Galeano, H., Sanchis-Gomar, F., Santos-Lozano, A., Fiuza-Luces, C., Morán, M., Emanuele, E., Joyner, M. J., & Lucia, A. (2015) · Rejuvenation Research · doi:10.1089/rej.2014.1623 · Cited by 413
Lipid modulation of skeletal muscle mass and function
Lipina, C., & Hundal, H. S. (2017) · Journal of Cachexia, Sarcopenia and Muscle · doi:10.1002/jcsm.12144 · Cited by 247
Aging Hallmarks: The Benefits of Physical Exercise
Rebelo-Marques, A., De Sousa Lages, A., Andrade, R., Ribeiro, C. F., Mota-Pinto, A., Carrilho, F., & Espregueira-Mendes, J. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00258 · Cited by 246
Muscle morphology and performance in master athletes: A systematic review and meta-analyses
Mckendry, J., Breen, L., Shad, B. J., & Greig, C. A. (2018) · Ageing Research Reviews · doi:10.1016/j.arr.2018.04.007 · Cited by 111
Piasecki, J., Ireland, A., Piasecki, M., Deere, K., Hannam, K., Tobias, J., & McPhee, J. S. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.01050 · Cited by 24
Metadata
- Authors
- Mikkelsen, U. R., Couppé, C., Karlsen, A., Grosset, J. F., Schjerling, P., Mackey, A. L., Klausen, H. H., Magnusson, S. P., & Kjær, M.
- Venue
- Mechanisms of Ageing and Development
- Publisher
- Elsevier BV
- Published
- 2013-11
- Volume
- 134
- Issue
- 11-12
- Pages
- 531-540
- ISSN
- 0047-6374
- Cited by
- 96
- References
- 13
- Language
- en
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.