The role of nitric oxide in cardiovascular diseases

The biochemistry of apoptosis

Hengartner, M. O. (2000) · Nature · doi:10.1038/35037710 · Cited by 5,779

Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly

Beckman, J. S., & Koppenol, W. H. (1996) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1996.271.5.c1424 · Cited by 5,513

Nitric oxide: an endogenous modulator of leukocyte adhesion.

Kubes, P., Suzuki, M., & Granger, D. N. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.11.4651 · Cited by 3,036

Diabetes and Atherosclerosis

Beckman, J. A., Creager, M. A., & Libby, P. (2002) · JAMA · doi:10.1001/jama.287.19.2570 · Cited by 2,765

Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells.

Garg, U. C., & Hassid, A. (1989) · Journal of Clinical Investigation · doi:10.1172/jci114081 · Cited by 2,154

Hypertension in mice lacking the gene for endothelial nitric oxide synthase

Huang, P. L., Huang, Z., Mashimo, H., Bloch, K. D., Moskowitz, M. A., Bevan, J. A., & Fishman, M. C. (1995) · Nature · doi:10.1038/377239a0 · Cited by 2,070

Hypercholesterolemia increases endothelial superoxide anion production.

Ohara, Y., Peterson, T. E., & Harrison, D. G. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116491 · Cited by 1,765

Platelets in atherothrombosis

Ruggeri, Z. M. (2002) · Nature Medicine · doi:10.1038/nm1102-1227 · Cited by 1,605

Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase

MacMicking, J. D., Nathan, C., Hom, G. J., Chartrain, N. A., Fletcher, D. S., Trumbauer, M. E., Stevens, K. A., Xie, Q. W., Sokol, K. A., Hutchinson, N. I., et al. (1995) · Cell · doi:10.1016/0092-8674(95)90085-3 · Cited by 1,445

ENDOGENOUS NITRIC OXIDE INHIBITS HUMAN PLATELET ADHESION TO VASCULAR ENDOTHELIUM

Radomski, M. W., Palmer, R. M. J., & Moncada, S. (1987) · The Lancet · doi:10.1016/s0140-6736(87)91481-4 · Cited by 1,437

REGULATORY EFFECTS OF ACUTE AND CHRONIC ENDURANCE EXERCISE ON NITRIC OXIDE AND REACTIVE OXYGEN SPECIES IN HUMAN CIRCULATING ANGIOGENIC CELLS

Jenkins, N. T. (2011) · University Libraries (University of Maryland)

A Maillard reaction product enhances eNOS activity in human endothelial cells

Schmitt, C. A., Heiß, E. H., Schachner, D., Aristei, Y., Severin, T., & Dirsch, V. M. (2010) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.200900330

Vascular actions of oleamide in health and disease

Hopps, J. J. (2013) · Nottingham ePrints (University of Nottingham)

PMCA as a regulator of calcium/calmodulin-dependent signal transduction pathways

Holton, M. (2009) · Wolverhampton Intellectual Repository and E-Theses (University of Wolverhampton)

Circulating Biomarkers Of Nitro-oxidative Stress In Young And Older Active And Inactive Men

Bjork, L., Jenkins, N. T., Witkowski, S., & Hagberg, J. M. (2010) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000384584.62912.b1

Association of Endothelial Nitric Oxide Synthase (Enos) Gene Polymorphism with Complications of Hbss in Ghanaian Sickle Cell Disease Patients

Antwi‐Boasiako, C. (2014)

Efeitos biomoduladores da pecticina da casca dos frutos de cacau (Theobroma Cacao l.) sobre macrófagos peritoneais de camundongos

Amorim, J. C. (2012) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)

Can restoration of endothelial insulin sensitivity rescue vascular function and repair in systemic insulin resistance

Sengupta, A. (2015) · White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)

Tetrahydrobiopterin attenuates ischemia-reperfusion injury following organ transplantation by targeting the nitric oxide synthase: investigations in an animal model

Cardini, B., Oberhuber, R., Hein, S. R., Watschinger, K., Hermann, M., Obrist, P., Werner‐Felmayer, G., Brandacher, G., Pratschke, J., Werner, E. R., et al. (2013) · Pteridines · doi:10.1515/pterid-2013-0006

Riesgo Cardiovascular en la Anorexia Nerviosa y en otras formas de Amenorrea Hipotalámica Funcional Relacionadas con la Desnutrición Cardiovascular risk in anorexia nerviosa and other forms of functional hypothalamic amenorrhea related to undernutrition

Fiszlejder, L., & Pablo, M. F. (2012)

Phosphodiesterase-5 Inhibitors in Cardioprotection

Thirunavukkarasu, M., & Ponnusamy, M. (2013) · CRC Press eBooks · doi:10.1201/b14663-28

Nitric Oxide Synthase and Olive Oil Hydroxytyrosol in Endothelial Cells

Schmitt, C. A., & Dirsch, V. M. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-374420-3.00138-8

Chronic Hyperhomocysteinemia Increases Inflammatory Markers in Hippocampus and Serum of Rats

Barcelos, R. R. (2012)

Rekrutierung von Immunzellen in das perivaskuläre Fettgewebe bei Adipositas – Bedeutung von Leptin

Herzberg, S. (2018) · doi:10.53846/goediss-6900

The Effect of Southern Indigenous Vegetables on Anti-inflammation

Seetapong, P. (2016) · PSU Knowledge Bank (Prince of Songkla University)

Animal model and therapeutic prospects for left ventricular hypertrophy and associated renal complicationPreprint

Ahmad, A., Riaz, Z., Sattar, M. Z. A., Khan, S. A., John, E. J., Arshad, S., Shah, S. T. A., Rafiq, M., Azam, M., & Qamar, R. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/638353

Mecanismos envolvidos no remodelamento vascular promovido pelo tratamento com omeprazol

Nogueira, R. C. (2019) · doi:10.11606/d.17.2019.tde-12072019-113549

Metabolismo de lípidos y disfunción endotelial en pacientes diabéticos tipo 2 tratados con insulina o hipoglucemiantes orales

Marra, C. A., de Bioquímica, C., & Molecular, B. (2013)

Efeitos da taurina em células endoteliais expostas in vitro á restrição de aminoácidos

Mendonça, K. C. P. (2020) · doi:10.47749/t/unicamp.2020.1161370

Biological activity of anthocyanins and their phenolic degradation products and metabolites in human vascular endothelial cells

Edwards, M. (2013) · UEA Digital Repository (University of East Anglia)

References

(2018) · Wiley eBooks · doi:10.1002/9781118829875.refs

Engineering and Sport Exercising

(2013) · Apple Academic Press eBooks · doi:10.1201/b15763-6

Caracterização farmacológica de doadores de sulfeto de hidrogênio (H2S) na resposta vasomotora in vitro de anéis de artéria mesentérica de camundongos.

Marques, L. A. D. C. (2020) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.42.2020.tde-05012021-145806

An Investigation into the Effects of Ubiquinone on Inflammation, Diabetic Myopathy and Endotheliopathy, and CBC Parameters in Diabetic Rats

Jbrael, Y. J., & Hamad, B. K. (2023) · Ibn AL- Haitham Journal For Pure and Applied Science · doi:10.30526/36.2.2976

Characteristics of bioactive molecules with antioxidant and biological activities of some medicinal and edible plants

Ouerfelli, M. (2021) · UPCommons institutional repository (Universitat Politècnica de Catalunya) · doi:10.5821/dissertation-2117-367332

Evaluation of the Effects of Vitamin C in Prognosis of Patients with Sepsis in Zanjan Vali- e-Asr Hospital in 2020

Karami, A., Fallahpour, F., Motamed, N., & Jafari, M. R. (2023) · Journal of Advances in Medical and Biomedical Research · doi:10.30699/jambs.31.147.364

Reatividade de acetatos trinucleares de rutênio com ligantes nitrito e óxido nítrico em meio aquoso

Barbosa, H. E. (2023) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.59.2023.tde-04122023-172715

Comorbidity of upper urinary tract stones and cardiovascular pathology: risk factors and common pathophysiological mechanisms

Кірієнко, Т. В., & Boyko, A. (2023) · Bukovinian Medical Herald · doi:10.24061/2413-0737.27.4.108.2023.19

How a Plant-Based Diet (PBD) Reduces In-Stent Restenosis (ISR) and Stent Thrombosis (ST)

Mulijono, D. (2024) · Cardiology Open Access · doi:10.33140/coa.09.01.05 · Cited by 4

Role of phenolic acids in treatment and prevention of cardiovascular diseases

Queiroz, M., Matos, P., Sena, C. M., Figueirinha, A., & Ramos, F. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-18538-0.00001-9

Matrix Gla Protein and Nitric Oxide Synthase‐3 Genetic Variants in Chronic Kidney Disease and Their Relation with Cardiovascular Risk

Priyadarshini, G., Parameswaran, S., Sahoo, J., Selvarajan, S., Ananthakrishnan, R., & Rajappa, M. (2024) · International Journal of Nephrology · doi:10.1155/2024/3850055

Analysis of the Immunomodulator Profile of Secondary Metabolites Derived from Streptomyces sp.

Gouveia, S. D. S. A., Santos, D. C. P., de Almeida, I. A., & de Miranda, R. D. C. M. (2024) · Revista de Gestão Social e Ambiental · doi:10.24857/rgsa.v18n10ed.esp-002

Covalently immobilized recombinant humanized collagen type III (rhCol III) for enhanced anticoagulation and endothelialization

Zhang, T., Li, L., Wang, Z., Luo, R., Li, Y., Wang, Y., & Zhang, X. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.147744

Atmospheric reactive oxygen and nitrogen species and their effects on air quality and human health

Yu, H. (2025) · Comprehensive analytical chemistry · doi:10.1016/bs.coac.2025.08.005

Binge drinking as a potential cardiometabolic risk factor during adolescence in rats: novel protective antinitrosative mechanism of folic acid via caveolin-1

Gallego‐López, M. D. C., Nogales, F., Herrera, I. R., Carreras, O., & Ojeda, M. L. (2025) · Hypertension Research · doi:10.1038/s41440-025-02455-x

Gut microbiota–derived polyamine pathways associated with mean blood pressure

Ikagawa, Y., Okamoto, S., Taniguchi, K., Mizoguchi, R., Hashimoto, A., Imamura, R., Arakawa, H., Ogura, K., Yanagihara, M., Tsujiguchi, H., et al. (2025) · Hypertension Research · doi:10.1038/s41440-025-02490-8

The antidepressant properties of selected methylene blue analogues

Delport, A. (2014)

High Glucose and Human Endothelial Cell Ageing

Bowers, L.-L. (2009) · OpenGrey (Institut de l'Information Scientifique et Technique)

On the Cellular Basis of Aerobic Fitness : Intensity-Dependence and Time-Course of Cardiomyocyte and Endothelial Adaptations to Exercise Training

Kemi, O. J. (2005) · BIBSYS Brage (BIBSYS (Norway))

Additional file 1 of Deciphering the benefits and intensity levels of primary metabolites from Allium macrostemon Bunge and Allium chinense G. Don

Qin, Z., Li, Y., Liu, D., Hua, Y., Lv, Y., Zhang, X., 范才莲, & Yang, J. (2024) · Figshare · doi:10.6084/m9.figshare.26749490

Biology of Extracellular Matrix in Pulmonary Vascular Pathology Associated with Chronic Lung Diseases

Yanagihara, T., Otsubo, K., & Kolb, M. R. J. (2025) · Respiratory medicine · doi:10.1007/978-3-032-03581-3_4

Assessment of Nitric Oxide Release In Vitro via Low-Level Daylight-Equivalent Blue or Red Light Irradiation

Hazell, G., Khazova, M., & O’Mahoney, P. (2026) · Antioxidants · doi:10.3390/antiox15020232

Préconditionnement myocardique et diabéte : effets aigus des AGEs sur le préconditionnement induit par la stimulation des récepteurs β1-adrénergiques et purinergiques. Rôle de la vitamine B6 (Pyridoxal-5- phosphate et pyridoxamine)

Alouane, L. (2012) · theses.fr (ABES) · doi:10.70675/daadca28z0435z40b0z91f6zc366c49c0b24

Caractérisation de la fonction micro et macrovasculaire chez les enfants drépanocytaires SS et SC : les effets de l'activité physique, du stress oxydant et les conséquences sur la sévérité clinique

Möckesch, B. (2017) · theses.fr (ABES) · doi:10.70675/c699856bzd341z459dzba46z662979e0db5a

Blackcurrant anthocyanin induces activation of NO pathway : role of sodium glucose cotransporter 1 and 2

Lee, H.-H. (2018) · theses.fr (ABES) · doi:10.70675/01af62dfzd4a2z462fz9af0z66d5873040e9

UHPLC-MS/MS-based Untargeted Metabolomics Reveals Changes in Metabolites of Ligusticum chuanxiong During Irradiation

Jia, X., Gao, P., Wang, Y., Fu, Y., Xu, P., & Huang, M. (2026) · Applied Biochemistry and Biotechnology · doi:10.1007/s12010-026-05629-6

Nitric oxide supplementation during extracorporeal resuscitation drives oxidative–inflammatory signaling and metabolic suppression in the post–cardiac arrest heart

Salama, A. B. M., Linardi, D., Mani, R., Tessari, M. M., Ou, Q., Salem, Y. Y., Abdulsaboor, A., Shaker, A. M., Gebreil, A., Elbakri, A., et al. (2026) · Molecular Medicine · doi:10.1186/s10020-026-01468-7

Impact of systemic diseases on periodontal remodeling: Mechanisms, mediators, and clinical relevance

Wolf, M. F., Schulze‐Späte, U., Dyke, T. E. V., Wolfart, S., Dietrich, T., Ortíz, A., Wu, Z., & Jankowski, J. (2026) · Periodontology 2000 · doi:10.1111/prd.70048 · Cited by 1

Dietary Nitrate Bioactivation at the Diet–Microbiota–Host Interface: The Enterosalivary Cycle, Food Matrix, Microbial Determinants and Health Implications—A Narrative Review Supported by a Structured Literature Search

Buzatu, G.-D., Dodocioiu, A. M., Ciupeanu-Călugăru, E. D., Rădulescu, D., & Trasca, E.-T. (2026) · Nutrients · doi:10.3390/nu18172841

Unravelling the Therapeutic Potential of Cysteine for Cardiovascular Health

Zainalabidin, S., Ravindran, G., Ghani, M. A. A., Azman, A. Z., Ping, C. Y., Ahmad, A. A., Yusof, N. L. M., & Jubaidi, F. F. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27188412

The effects of chronic beetroot juice supplementation with resistance training on skeletal muscle mitochondrial and redox markers in middle-aged and older adults

Mueller, B. J., McIntosh, M. C., Tiede, D., Anglin, D. A., Kontos, G. J., Lewis, D. T., Goodlett, M. D., Frugé, A. D., Mobley, C. B., Judd, R. L., et al. (2026) · European Journal of Applied Physiology · doi:10.1007/s00421-026-06460-x · Cited by 1

Nitric Oxide Signaling in Cardiovascular Disease: Redox Dysregulation, Biomarkers, and Therapeutic Challenges

Alagh, K., Zalzal, R. N., Kumar, A., Xiong, Y., Xia, Z., & Kamra, K. (2026) · Antioxidants · doi:10.3390/antiox15111390

Adiponectin : a novel circulating anti-thrombotic factor in humans?

Yousaf, T. A. (2011) · Repository@Hull (Worktribe) (University of Hull)

Mechanisms responsible for homocysteine mediated damage to human endothelial cells : the role of oxidative stress in atherogenesis

Alkhoury, K. (2009) · OpenGrey (Institut de l'Information Scientifique et Technique)

Long-term heme synthesis inhibition: vascular implications

Benjamin, C. D. (2008)

Mecanismos de sintese e degradação do radical oxido nitrico pela mitocondria de Arabidopsis thaliana

Wulff, A. (2008) · doi:10.47749/t/unicamp.2008.428267

Nitric oxide and pathogenic mechanisms involved in the development of vascular diseases

Napoli, C., & Ignarro, L. J. (2009) · Archives of Pharmacal Research · doi:10.1007/s12272-009-1801-1 · Cited by 281

Nitric Oxide in the Pathogenesis of Cardiac Disease

Raij, L. R. (2006) · Journal of Clinical Hypertension · doi:10.1111/j.1524-6175.2006.06025.x · Cited by 59

“Nitric Oxide Deficiency” in Cardiovascular Diseases: Cardiovascular Protection by Restoration of Endothelial Nitric Oxide Production

Kauser, K. Z., & Rubanyi, G. M. (2002) · CRC Press eBooks · doi:10.1201/b12626-1

NITRIC OXIDE-DEPENDENT ENDOTHELIAL FUNCTION AND CARDIOVASCULAR DISEASE

Desjardins, F., & Balligand, J. (2006) · Acta Clinica Belgica · doi:10.1179/acb.2006.052 · Cited by 86

Role of nitric oxide in cardiovascular disease: focus on the endothelium

Cannon, R. O. (1998) · Clinical Chemistry · doi:10.1093/clinchem/44.8.1809 · Cited by 346