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Cited by 296

The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.

Anti-inflammatory properties of α- and γ-tocopherol

Open access
Reiter, Elke, Jiang, Qing, Christen, Stephan·2007·Molecular Aspects of Medicine
DOI 10.1016/j.mam.2007.01.003
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Abstract

Natural vitamin E consists of four different tocopherol and four different tocotrienol homologues (alpha,beta, gamma, delta) that all have antioxidant activity. However, recent data indicate that the different vitamin E homologues also have biological activity unrelated to their antioxidant activity. In this review, we discuss the anti-inflammatory properties of the two major forms of vitamin E, alpha-tocopherol (alphaT) and gamma-tocopherol (gammaT), and discuss the potential molecular mechanisms involved in these effects. While both tocopherols exhibit anti-inflammatory activity in vitro and in vivo, supplementation with mixed (gammaT-enriched) tocopherols seems to be more potent than supplementation with alphaT alone. This may explain the mostly negative outcomes of the recent large-scale interventional chronic disease prevention trials with alphaT only and thus warrants further investigation.

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Metadata

Authors
Reiter, E., Jiang, Q., & Christen, S.
Venue
Molecular Aspects of Medicine
Publisher
Elsevier BV
Published
2007-10
Volume
28
Issue
5-6
Pages
668-691
ISSN
0098-2997 (ISSN-L)
DOI
10.1016/j.mam.2007.01.003
OpenAlex
W2006154113
Cited by
296
References
8
FWCI
7.30
Type
journal article
Language
en
Open access
green

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