Alcohol and Cardiovascular Health: The Dose Makes the Poison…or the Remedy
Abstract
Habitual light to moderate alcohol intake (up to 1 drink per day for women and 1 or 2 drinks per day for men) is associated with decreased risks for total mortality, coronary artery disease, diabetes mellitus, congestive heart failure, and stroke. However, higher levels of alcohol consumption are associated with increased cardiovascular risk. Indeed, behind only smoking and obesity, excessive alcohol consumption is the third leading cause of premature death in the United States. Heavy alcohol use (1) is one of the most common causes of reversible hypertension, (2) accounts for about one-third of all cases of nonischemic dilated cardiomyopathy, (3) is a frequent cause of atrial fibrillation, and (4) markedly increases risks of stroke-both ischemic and hemorrhagic. The risk-to-benefit ratio of drinking appears higher in younger individuals, who also have higher rates of excessive or binge drinking and more frequently have adverse consequences of acute intoxication (for example, accidents, violence, and social strife). In fact, among males aged 15 to 59 years, alcohol abuse is the leading risk factor for premature death. Of the various drinking patterns, daily low- to moderate-dose alcohol intake, ideally red wine before or during the evening meal, is associated with the strongest reduction in adverse cardiovascular outcomes. Health care professionals should not recommend alcohol to nondrinkers because of the paucity of randomized outcome data and the potential for problem drinking even among individuals at apparently low risk. The findings in this review were based on a literature search of PubMed for the 15-year period 1997 through 2012 using the search terms alcohol, ethanol, cardiovascular disease, coronary artery disease, heart failure, hypertension, stroke, and mortality. Studies were considered if they were deemed to be of high quality, objective, and methodologically sound.
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The relationship between alcohol use and cardiovascular disease outcomes is complex, as different dimensions play a role for different outcomes.
“The relationship between alcohol use and cardiovascular disease outcomes is complex, as different dimensions play a role for different outcomes 238, 239, 240.”
From The relationship between different dimensions of alcohol use and the burden of disease—an update (2017) · cites this paper as [239]
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Schooling, C. M., Sun, W., Ho, S. Y., Chan, W. M., Tham, M. K., Ho, K. S., Leung, G. M., & Lam, T. H. (2008) · PLoS ONE · doi:10.1371/journal.pone.0002370 · Cited by 35 · see citing works
Alcohol Consumption and the Incidence of Hypertension in a Mediterranean Cohort: The SUN Study
Núñez-Córdoba, J. M., Martínez‐González, M. Á., Bes‐Rastrollo, M., Toledo, E., Beunza, J. J., & Alonso, Á. (2009) · Revista Española de Cardiología (English Edition) · doi:10.1016/s1885-5857(09)72227-3 · Cited by 34 · see citing works
Alcohol Consumption and Risk of Heart Failure: A Meta-Analysis
Padilla, H. M., Gaziano, J. M., & Djoussé, L. (2010) · The Physician and Sportsmedicine · doi:10.3810/psm.2010.10.1812 · Cited by 33 · see citing works
Wakabayashi, I. (2010) · Angiology · doi:10.1177/0003319709358694 · Cited by 31 · see citing works
Mukamal, K. J., Girotra, S. R., & Mittleman, M. A. (2006) · American Heart Journal · doi:10.1016/j.ahj.2005.05.017 · Cited by 21 · see citing works
Sidorenkov, O., Nilssen, O., Nieboer, E., Kleshchinov, N., & Grjibovski, A. M. (2011) · International Journal of Epidemiology · doi:10.1093/ije/dyr145 · Cited by 20 · see citing works
Carter, M. D., Lee, J. H., Buchanan, D. M., Peterson, E. D., Tang, F., Reid, K. J., Spertus, J. A., Valtos, J., & O’Keefe, J. H. (2010) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2010.01.339 · Cited by 14 · see citing works
Self-citationAlcohol Consumption and Risk of Heart Failure
Gonçalves, A. (2015) · Digital Access to Scholarship at Harvard (DASH) (Harvard University) · Cited by 8 · see citing works
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The relationship between different dimensions of alcohol use and the burden of disease—an update
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Alcohol Consumption and Obesity: An Update
Traversy, G., & Chaput, J.-P. (2015) · Current Obesity Reports · doi:10.1007/s13679-014-0129-4 · Cited by 629 · see citing works
Potential Toxicity of Iron Oxide Magnetic Nanoparticles: A Review
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Connor, J. P., Haber, P. S., & Hall, W. D. (2016) · The Lancet · doi:10.1016/s0140-6736(15)00122-1 · Cited by 389 · see citing works
Cardiovascular risks and benefits of moderate and heavy alcohol consumption
Fernández‐Solà, J. (2015) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2015.91 · Cited by 359 · see citing works
Running as a Key Lifestyle Medicine for Longevity
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Yun, J.-S., & Ko, S.-H. (2021) · Metabolism · doi:10.1016/j.metabol.2021.154838 · Cited by 292 · see citing works
Alcohol and Atrial Fibrillation
Voskoboinik, A., Prabhu, S., Ling, L., Kalman, J. M., & Kistler, P. M. (2016) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2016.08.074 · Cited by 288 · see citing works
Metabolic Methanol: Molecular Pathways and Physiological Roles
Dorokhov, Y. L., Shindyapina, A. V., Sheshukova, E. V., & Komarova, T. V. (2015) · Physiological Reviews · doi:10.1152/physrev.00034.2014 · Cited by 226 · see citing works
Contribution of Red Wine Consumption to Human Health Protection
Snopek, L., Mlček, J., Sochorová, L., Baroň, M., Hlaváčová, I., Juríková, T., Kizek, R., Sedláčková, E., & Sochor, J. (2018) · Molecules · doi:10.3390/molecules23071684 · Cited by 224 · see citing works
3D-printed epifluidic electronic skin for machine learning–powered multimodal health surveillance
Song, Y., Tay, R. Y., Li, J., Xu, C., Min, J., Sani, E. S., Kim, G., Heng, W., Kim, I. H., & Gao, W. F. (2023) · Science Advances · doi:10.1126/sciadv.adi6492 · Cited by 221 · see citing works
Gibbs, B. B., Hivert, M., Jerome, G. J., Kraus, W. E., Rosenkranz, S. K., Schorr, E. N., Spartano, N. L., & Lobelo, F. (2021) · Hypertension · doi:10.1161/hyp.0000000000000196 · Cited by 198 · see citing works
Morin, D. P., Bernard, M. L., Madias, C. A., Rogers, P. A., Thihalolipavan, S., & Estes, N. A. M. (2016) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2016.08.022 · Cited by 196 · see citing works
Alcohol and CV Health: Jekyll and Hyde J-Curves
O’Keefe, E. L., DiNicolantonio, J. J., O’Keefe, J. H., & Lavie, C. J. (2018) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2018.02.001 · Cited by 183 · see citing works
Self-citationThe Effects of Ethanol on the Heart: Alcoholic Cardiomyopathy
Fernández‐Solà, J. (2020) · Nutrients · doi:10.3390/nu12020572 · Cited by 176 · see citing works
Promoting Successful Cognitive Aging: A Ten-Year Update
Krivanek, T. J., Gale, S. A., McFeeley, B. M., Nicastri, C. M., & Daffner, K. R. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-201462 · Cited by 181 · see citing works
Putative Role of Red Wine Polyphenols against Brain Pathology in Alzheimer’s and Parkinson’s Disease
Caruana, M., Cauchi, R. J., & Vassallo, N. (2016) · Frontiers in Nutrition · doi:10.3389/fnut.2016.00031 · Cited by 162 · see citing works
Alcohol’s Impact on the Cardiovascular System
Roerecke, M. (2021) · Nutrients · doi:10.3390/nu13103419 · Cited by 170 · see citing works
Capítulo 1 - Conceituação, Epidemiologia e Prevenção Primária
Malachias, M. V. B., Souza, W., Plavnik, F. L., Rodrigues, C., Brandão, A., Neves, M. F., Bortolotto, L. A., Franco, R., Figueiredo, C., Jardim, P., et al. (2016) · Arquivos Brasileiros de Cardiologia · doi:10.5935/abc.20160151 · Cited by 140 · see citing works
Impact of age, clinical conditions, and lifestyle on routine semen parameters and sperm kinematics
Verón, G. L., Tissera, A. D., Bello, R., Beltramone, F., Estofan, G. M., Molina, R. I., & Vazquez-Levin, M. H. (2018) · Fertility and Sterility · doi:10.1016/j.fertnstert.2018.03.016 · Cited by 122 · see citing works
Kabwama, S. N., Ndyanabangi, S., Mutungi, G. N., Wesonga, R., Bahendeka, S., & Guwatudde, D. (2016) · Global Health Action · doi:10.3402/gha.v9.31302 · Cited by 118 · see citing works
Alcoholic cardiomyopathy: What is known and what is not known
Mirijello, A., Tarli, C., Vassallo, G. A., Sestito, L., Antonelli, M., D’Angelo, C., Ferrulli, A., Cosmo, S. D., Gasbarrini, A., & Addolorato, G. (2017) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2017.06.014 · Cited by 116 · see citing works
Cardiovascular effects of alcohol consumption
Rehm, J. T., & Roerecke, M. (2017) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2017.06.002 · Cited by 113 · see citing works
Lifestyle Medicine and the Management of Cardiovascular Disease
Doughty, K. N., Pilar, N. X. D., Audette, A., & Katz, D. L. (2017) · Current Cardiology Reports · doi:10.1007/s11886-017-0925-z · Cited by 104 · see citing works
Alcohol Effects on Cardiac Function
Gardner, J. D., & Mouton, A. J. (2015) · Comprehensive physiology · doi:10.1002/cphy.c140046 · Cited by 102 · see citing works
Toxicology and the biological role of methanol and ethanol: Current view
Pohanka, M. (2015) · Biomedical Papers · doi:10.5507/bp.2015.023 · Cited by 95 · see citing works
Draijer, R., de Graaf, Y., Slettenaar, M., de Groot, E., & Wright, C. (2015) · Nutrients · doi:10.3390/nu7053138 · Cited by 95 · see citing works
Quantifying the contribution of alcohol to cardiomyopathy: A systematic review
Rehm, J., Hasan, O. S. M., Imtiaz, S., & Neufeld, M. (2017) · Alcohol · doi:10.1016/j.alcohol.2017.01.011 · Cited by 92 · see citing works
Saha, B., Bruneau, J. C., Kodys, K., & Szabó, G. (2015) · The Journal of Immunology · doi:10.4049/jimmunol.1402190 · Cited by 93 · see citing works
A Clinician’s Guide for Trending Cardiovascular Nutrition Controversies
Freeman, A. M., Morris, P. B., Aspry, K. E., Gordon, N. F., Barnard, N. D., Esselstyn, C. B., Ros, E., Devries, S. R., O’Keefe, J. H., Miller, M. J., et al. (2018) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2018.05.030 · Cited by 93 · see citing works
Self-citationChang, K. J., Thach, M. L., & Olsen, J. E. (2016) · Wine Economics and Policy · doi:10.1016/j.wep.2016.09.001 · Cited by 80 · see citing works
Comportamentos em saúde e o controle da hipertensão arterial: resultados do ELSI-BRASIL
Firmo, J. O. A., Peixoto, S. V., Filho, A. I. D. L., Júnior, P. R. B. D. S., de Andrade, F. B., Lima‐Costa, M. F., & Mambrini, J. V. D. M. (2019) · Cadernos de Saúde Pública · doi:10.1590/0102-311x00091018 · Cited by 72 · see citing works
André, S., Andreozzi, F., Overstraeten, C. V., Youssef, S. B., Bold, I., Carlier, S., Gruwez, A., Bruyneel, A.-V., & Bruyneel, M. (2020) · Respiratory Research · doi:10.1186/s12931-020-1284-7 · Cited by 72 · see citing works
Passaglia, P., Ceron, C. S., Mecawi, A. S., Antunes‐Rodrigues, J., Coelho, E. B., & Tirapelli, C. R. (2015) · Vascular Pharmacology · doi:10.1016/j.vph.2015.04.002 · Cited by 67 · see citing works
Risk of cardiovascular diseases in relation to substance use disorders.
Gan, W.-Q., Buxton, J., Scheuermeyer, F., Palis, H., Zhao, B., Desai, R., Janjua, N., & Slaunwhite, A. (2021) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2021.109132 · Cited by 57 · see citing works
Role of autophagy and regulatory mechanisms in alcoholic cardiomyopathy
Wang, S., & Ren, J. T. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2018.03.016 · Cited by 64 · see citing works
Rehm, J. T., Shield, K. D., Roerecke, M., & Gmel, G. E. (2016) · BMC Public Health · doi:10.1186/s12889-016-3026-9 · Cited by 63 · see citing works
Moderate Beer Intake and Cardiovascular Health in Overweight Individuals
Padró, T., Muñoz‐García, N., Vilahur, G., Chagas, P., Deyà, A., Antonijoan, R. M., & Badimón, L. (2018) · Nutrients · doi:10.3390/nu10091237 · Cited by 63 · see citing works
Sasot, G., Martínez‐Huélamo, M., Vallverdú‐Queralt, A., Mercader-Martí, M., Estruch, R., & Lamuela-Raventós, R. M. (2017) · Food Research International · doi:10.1016/j.foodres.2017.01.020 · Cited by 61 · see citing works
Klaming, R., Annese, J., Veltman, D. J., & Comijs, H. C. (2017) · Aging, Neuropsychology, and Cognition · doi:10.1080/13825585.2016.1226746 · Cited by 59 · see citing works
Health Effects of Red Wine Consumption: A Narrative Review of an Issue That Still Deserves Debate
Lombardo, M., Feraco, A., Camajani, E., Caprio, M., & Armani, A. (2023) · Nutrients · doi:10.3390/nu15081921 · Cited by 59 · see citing works
Joo, Y. S., Koh, H. B., Nam, K. H., Lee, S., Kim, J., Lee, C., Yun, H., Park, J. T., Kang, E. W., Chang, T. I., et al. (2019) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2019.06.014 · Cited by 59 · see citing works
Zheng, Q., Lin, W., Liu, C.-G., Zhou, Y., Chen, T.-H., Zhang, L.-Q., Zhang, X.-H., Yu, S., Wu, Q., Jin, Z., et al. (2020) · BMC Public Health · doi:10.1186/s12889-020-08630-8 · Cited by 46 · see citing works
A scoping review on consumer behaviour related to wine and health
Deroover, K., Siegrist, M., Brain, K., McIntyre, J., & Bucher, T. (2021) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2021.03.057 · Cited by 61 · see citing works
Effects of Age Discrimination on Self-perceptions of Aging and Cancer Risk Behaviors
Hooker, K. A., Mejía, S. T., Phibbs, S. C., Tan, E. J., & Stevens, J. (2019) · The Gerontologist · doi:10.1093/geront/gny183 · Cited by 55 · see citing works
Wallach, J. D., Serghiou, S., Chu, L., Egilman, A. C., Vasiliou, V., Ross, J. S., & Ioannidis, J. P. A. (2020) · BMC Medical Research Methodology · doi:10.1186/s12874-020-0914-6 · Cited by 55 · see citing works
Huang, C., Zhan, J., Liu, Y., Li, D., Wang, S.-Q., & He, Q. (2014) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2014.05.014 · Cited by 53 · see citing works
He, Y., Qiu, H., Wang, W., Lin, Y., & Ho, K. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.170639 · Cited by 51 · see citing works
Jorge, E., Lopez‐Valeiras, E., & Sánchez, M. B. G. (2020) · Journal of Cleaner Production · doi:10.1016/j.jclepro.2020.120601 · Cited by 51 · see citing works
The Association of Alcohol Consumption with Glaucoma and Related Traits
Stuart, K. V., Luben, R., Warwick, A., Madjedi, K. M., Patel, P. J., Biradar, M. I., Sun, Z., Chia, M. A., Pasquale, L. R., Wiggs, J. L., et al. (2022) · Ophthalmology Glaucoma · doi:10.1016/j.ogla.2022.11.008 · Cited by 49 · see citing works
Moderate alcohol consumption and atherosclerosis
Huang, Y., Li, Y., Zheng, S., Yang, X., Wang, T., & Zeng, J. (2017) · Wiener klinische Wochenschrift · doi:10.1007/s00508-017-1235-6 · Cited by 49 · see citing works
Degerud, E., Ariansen, I., Ystrøm, E., Graff‐Iversen, S., Høiseth, G., Mørland, J. G., Smith, G. D., & Næss, Ø. (2018) · PLoS Medicine · doi:10.1371/journal.pmed.1002476 · Cited by 48 · see citing works
Health Lifestyles in Late Middle Age
Cockerham, W. C., Wolfe, J. D., & Bauldry, S. (2019) · Research on Aging · doi:10.1177/0164027519884760 · Cited by 47 · see citing works
Shen, C., Wang, C., Han, S., Wang, Z., Dong, Z., Zhao, X., Wang, P., Zhu, H., Sun, X., Ma, X., et al. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2016.11.016 · Cited by 47 · see citing works
D'Alessandro, A., Lampignano, L., & Pergola, G. D. (2019) · Nutrients · doi:10.3390/nu11061296 · Cited by 48 · see citing works
Nutrición y salud cardiovascular
Berciano, S., & Ordovás, J. M. (2014) · Revista Española de Cardiología · doi:10.1016/j.recesp.2014.05.003 · Cited by 44 · see citing works
Risk of cardiac death among cancer survivors in the United States: a SEER database analysis
Abdel-Rahman, O. M. (2017) · Expert Review of Anticancer Therapy · doi:10.1080/14737140.2017.1344099 · Cited by 44 · see citing works
Manolis, T. A., Manolis, A. S., & Manolis, A. S. (2018) · Alcohol · doi:10.1016/j.alcohol.2018.08.011 · Cited by 45 · see citing works
Brellenthin, A. G., & Lee, D.-C. (2018) · Progress in Preventive Medicine · doi:10.1097/pp9.0000000000000018 · Cited by 46 · see citing works
Poppitt, S. D. (2015) · Nutrients · doi:10.3390/nu7085304 · Cited by 42 · see citing works
Temporal Trends in Substance Use and Cardiovascular Disease–Related Mortality in the United States
Minhas, A. M. K., Kewcharoen, J., Hall, M. E., Warraich, H. J., Greene, S. J., Shapiro, M. D., Michos, E. D., Sauer, A. J., & Abramov, D. (2024) · Journal of the American Heart Association · doi:10.1161/jaha.123.030969 · Cited by 41 · see citing works
Using Physical Activity to Enhance Health Outcomes Across the Life Span
Roychowdhury, D. (2020) · Journal of Functional Morphology and Kinesiology · doi:10.3390/jfmk5010002 · Cited by 44 · see citing works
Gomes, J. M. G., Fabrini, S. P., & Alfenas, R. D. C. G. (2016) · Archives of Endocrinology and Metabolism · doi:10.1590/2359-3997000000206 · Cited by 39 · see citing works
Alcohol Consumption and Risk of Incident Frailty: The English Longitudinal Study of Aging
Kojima, G., Jivraj, S., Iliffe, S., Falcaro, M., Liljas, A. E. M., & Walters, K. R. (2018) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2018.10.011 · Cited by 39 · see citing works
Richard, E., Kritz‐Silverstein, D. C., Laughlin, G. A., Fung, T. T., Barrett-Connor, E. L., & McEvoy, L. K. (2017) · Journal of Alzheimer s Disease · doi:10.3233/jad-161153 · Cited by 38 · see citing works
Capítulo 3 - Avaliação Clínica e Complementar
Malachias, M. V. B., Souza, W., Plavnik, F. L., Rodrigues, C., Brandão, A., Neves, M. F., Bortolotto, L. A., Franco, R., Figueiredo, C., Jardim, P., et al. (2016) · Arquivos Brasileiros de Cardiologia · doi:10.5935/abc.20160153 · Cited by 36 · see citing works
Sexual Dysfunction in Heart Failure Patients
Jaarsma, T., Fridlund, B., & Mårtensson, J. (2014) · Current Heart Failure Reports · doi:10.1007/s11897-014-0202-z · Cited by 36 · see citing works
Barr, T., Girke, T., Sureshchandra, S., Nguyen, C., Grant, K. A., & Messaoudi, I. (2015) · The Journal of Immunology · doi:10.4049/jimmunol.1501527 · Cited by 36 · see citing works
Rehm, J. T., Anderson, P., Prieto, J. A. A., Armstrong, I. J., Aubin, H., Bachmann, M., Bastús, N. B., Brotons, C., Burton, R., Cardoso, M., et al. (2017) · BMC Medicine · doi:10.1186/s12916-017-0934-1 · Cited by 36 · see citing works
Alcohol Intake and Arterial Hypertension: Retelling of a Multifaceted Story
Vacca, A., Bulfone, L., Cicco, S., Brosolo, G., Porto, A. D., Soardo, G., Catena, C., & Sechi, L. A. (2023) · Nutrients · doi:10.3390/nu15040958 · Cited by 38 · see citing works
Low Vs. High Alcohol: Central Benefits Vs. Detriments
Tizabi, Y., Getachew, B., Ferguson, C. L., Csoka, A. B., Thompson, K. M., Gómez-Paz, A., Kučerová, J., & Taylor, R. E. (2018) · Neurotoxicity Research · doi:10.1007/s12640-017-9859-x · Cited by 35 · see citing works
Prevalence of Lebanese stroke survivors: A comparative pilot study
Lahoud, N., Salameh, P., Saleh, N., & Hosseini, H. (2015) · Journal of Epidemiology and Global Health · doi:10.1016/j.jegh.2015.10.001 · Cited by 33 · see citing works
Logue, M. W., Miller, M. W., Sherva, R., Zhang, R., Harrington, K. M., Fonda, J. R., Merritt, V. C., Panizzon, M. S., Hauger, R. L., Wolf, E. J., et al. (2022) · Alzheimer s & Dementia · doi:10.1002/alz.12870 · Cited by 34 · see citing works
Yang, Q., He, Y., Cai, D.-P., Yang, X., & Xu, H. (2016) · Scientific Reports · doi:10.1038/srep35463 · Cited by 32 · see citing works
Kawasoe, S., Kubozono, T., Yoshifuku, S., Ojima, S., Miyata, M., Miyahara, H., Maenohara, S., & Ohishi, M. (2018) · Circulation Journal · doi:10.1253/circj.cj-18-0508 · Cited by 32 · see citing works
Are Sustainable Consumers Health Conscious? A Segmentation Study of Wine Consumers
Ghvanidze, S., Velikova, N., Dodd, T. H., & Oldewage-Theron, W. H. (2019) · Journal of Food Products Marketing · doi:10.1080/10454446.2019.1640160 · Cited by 33 · see citing works
Georgescu, O. Ş., Martin, L., Târtea, G. C., Rotaru-Zăvăleanu, A. D., Dinescu, S. N., Vasile, R. C., Greșiță, A., Gheorman, V., Aldea, M., & Dinescu, V. C. (2024) · Life · doi:10.3390/life14091134 · Cited by 37 · see citing works
Udo, T., Vásquez, E., & Shaw, B. A. (2015) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2015.10.008 · Cited by 31 · see citing works
Catena, C., Colussi, G., Verheyen, N., Novello, M., Fagotto, V., Soardo, G., & Sechi, L. A. (2016) · Hypertension · doi:10.1161/hypertensionaha.116.08145 · Cited by 31 · see citing works
Nonpharmacologic management of hypertension
Ozemek, C., Phillips, S. A., Popović, D., Laddu, D., Fancher, I. S., Arena, R. A., & Lavie, C. J. (2017) · Current Opinion in Cardiology · doi:10.1097/hco.0000000000000406 · Cited by 31 · see citing works
Self-citationJongenelis, M. I., Pratt, I., Slevin, T. J., Chikritzhs, T. N., Liang, W., & Pettigrew, S. (2018) · Health Education Research · doi:10.1093/her/cyy025 · Cited by 31 · see citing works
Microbiota for production of wine with enhanced functional components
James, A., Yao, T., Ke, H., & Wang, Y. (2023) · Food Science and Human Wellness · doi:10.1016/j.fshw.2023.02.008 · Cited by 30 · see citing works
Date Fruits as Raw Material for Vinegar and Non-Alcoholic Fermented Beverages
Cantadori, E., Brugnoli, M., Centola, M., Uffredi, E., Colonello, A., & Gullo, M. (2022) · Foods · doi:10.3390/foods11131972 · Cited by 30 · see citing works
Capítulo 14 – Crise Hipertensiva
Malachias, M. V. B., Souza, W., Plavnik, F. L., Rodrigues, C., Brandão, A., Neves, M. F., Bortolotto, L. A., Franco, R., Figueiredo, C., Jardim, P., et al. (2016) · Arquivos Brasileiros de Cardiologia · doi:10.5935/abc.20160164 · Cited by 30 · see citing works
Rehm, J. T., Prieto, J. A. A., Beier, M., Duhot, D., Rossi, A., Schulte, B., Zarco, J., Aubin, H., Bachmann, M., Grimm, C. J., et al. (2016) · BMC Family Practice · doi:10.1186/s12875-016-0529-5 · Cited by 30 · see citing works
Justice, M., Ferrugia, A., Beidler, J., Penprase, J. C., Cintora, P., Erwin, D., Medrano, O., Brasser, S. M., & Hong, M. Y. (2018) · Alcohol and Alcoholism · doi:10.1093/alcalc/agy079 · Cited by 29 · see citing works
Knapper, J. T., Ghasemzadeh, N., Khayata, M., Patel, S. P., Quyyumi, A. A., Mendis, S., Mensah, G. A., Taubert, K. A., & Sperling, L. S. (2015) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2015.07.008 · Cited by 29 · see citing works
Daily alcohol consumption and sickness absence in the GAZEL cohort
Morois, S., Airagnes, G., Lemogne, C., Leclerc, A., Limosin, F., Goldberg, S., Herquelot, É., Goldberg, M., & Zins, M. (2017) · European Journal of Public Health · doi:10.1093/eurpub/ckx012 · Cited by 28 · see citing works
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The Prognostic Factors of Alcoholic Cardiomyopathy
Fang, W., Luo, R., Tang, Y., Hua, W., Fu, M. L. X., Chen, W., Lai, L. F., & Li, X. (2018) · Medicine · doi:10.1097/md.0000000000011744 · Cited by 28 · see citing works
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Research trends and hotspots of post-stroke cognitive impairment: a bibliometric analysis
Chi, X., Fan, X., Fu, G.-J., Liu, Y., Zhang, Y., & Shen, W. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1184830 · Cited by 29 · see citing works
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Alcohol Use and Breast Cancer Survival among Participants in the Women's Health Initiative
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“The Bottle Is My Wife”: Exploring Reasons Why Men Drink Alcohol in Ugandan Fishing Communities
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Increased Mortality in Hip Fracture Patients Living Alone: A NOREPOS Study
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- Authors
- O’Keefe, J. H., Bhatti, S. K., Bajwa, A., DiNicolantonio, J. J., & Lavie, C. J.
- Affiliations
- Saint Luke's Hospital (US)
- The University of Queensland (AU)
- Corresponding author
- O’Keefe, James H.
- Venue
- Mayo Clinic Proceedings
- Publisher
- Elsevier BV
- Published
- 2014-03
- Volume
- 89
- Issue
- 3
- Pages
- 382-393
- ISSN
- 0025-6196 (ISSN-L)
- OpenAlex
- W2042273266
- Semantic Scholar
- fb99861a75849bf01ecd526f770d9df083ecff23
- Cited by
- 406
- References
- 96
- Citations by year
- 2026: 20 · 2025: 20 · 2024: 27 · 2023: 41 · 2022: 31 · 2021: 33 · 2020: 43 · 2019: 22 · 2018: 39 · 2017: 35 · 2016: 40 · 2015: 42 · 2014: 13
- FWCI
- 6.12
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Mayo Clinic Proceedings (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Pharmacology › Coffee research and impacts
- Keywords
- alcohol consumption, cardiovascular health, moderate drinking, heavy drinking, binge drinking, coronary artery disease, stroke, hypertension, congestive heart failure, diabetes mellitus, premature mortality, red wine, atrial fibrillation, non-ischemic dilated cardiomyopathy, risk-benefit ratio
- MeSH terms
- Alcohol Drinking, Ethanol, Alcoholic Beverages, Cardiotonic Agents, Cardiovascular Diseases, Dose-Response Relationship, Drug, Humans, Primary Prevention, Risk Factors, United States, Health Behavior, Secondary Prevention
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