Quantifying the contribution of alcohol to cardiomyopathy: A systematic review
Abstract
Alcohol has a direct toxic impact on the heart, and while there is an ICD code for alcoholic cardiomyopathy, the burden of alcohol-attributable cardiomyopathy is not clear. For the usual estimation of this burden via population-attributable fractions, one would need to determine the risk relationships, i.e., average risk associated with different dimensions of alcohol exposure. The most important among these risk relationships is the dose-response relationship with different levels of average alcohol consumption. To establish risk relationships, we systematically searched for all studies on dose-response relationships, directly and indirectly, via reviews. The results did not permit computation of pooled estimates through meta-analyses. There were clear indications that heavy drinking (≥80 g per day) over several years was linked to high risk of cardiomyopathy, with greater lifetime exposure of alcohol linked to higher risks. Some studies indicated potential effects of patterns of drinking as well. As such, the global quantification of alcohol-attributable cardiomyopathy will have to rely on other methods than those used conventionally.
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Alcoholic cardiomyopathy (I42.6) as a cause of death is available in approximately half of the countries as a cause of death.
“For example, alcoholic cardiomyopathy (I42.6) as a cause of death is available in approximately half of the countries as a cause of death 39, and thus could be included as part of alcohol attributable mortality in these countries.”
From The relationship between different dimensions of alcohol use and the burden of disease—an update (2017) · cites this paper as [39]
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Rosenberg, M., & Frey, N. (2010) · Der Kardiologe · doi:10.1007/s12181-009-0218-x · Cited by 2 · see citing works
Patologie cardiache alcool-correlate
Correale, M., Laonigro, I., Altomare, E., et al. (2009) · Giornale italiano di cardiologia · doi:10.1714/588.6937 · Cited by 1 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
The relationship between different dimensions of alcohol use and the burden of disease—an update
Rehm, J., Gmel, G. E., Gmel, G., Hasan, O. S. M., Imtiaz, S., Popova, S., Probst, C., Roerecke, M., Room, R., Samokhvalov, A. V., et al. (2017) · Addiction · doi:10.1111/add.13757 · Cited by 1,204 · see citing works
Self-citationRehm, J., & Room, R. (2017) · Nordic Studies on Alcohol and Drugs · doi:10.1177/1455072517704795 · Cited by 31 · see citing works
Self-citation
- Authors
- Rehm, J., Hasan, O. S. M., Imtiaz, S., & Neufeld, M.
- Affiliations
- Centre for Addiction and Mental Health (CA)
- Corresponding author
- Rehm, Jürgen
- Venue
- Alcohol
- Publisher
- Elsevier BV
- Published
- 2017-06
- Volume
- 61
- Pages
- 9-15
- ISSN
- 0741-8329 (ISSN-L)
- OpenAlex
- W2605612208
- Cited by
- 92
- References
- 111
- Citations by year
- 2026: 8 · 2025: 12 · 2024: 10 · 2023: 8 · 2022: 11 · 2021: 14 · 2020: 6 · 2019: 11 · 2018: 6 · 2017: 6
- FWCI
- 1.27
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Alcohol (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Keywords
- alcoholic cardiomyopathy, population attributable fraction, dose-response relationship, heavy drinking, drinking patterns, alcohol consumption, cardiovascular risk
- MeSH terms
- Adult, Age Factors, Alcohol Drinking, Ethanol, Alcoholism, Dose-Response Relationship, Drug, Ethnicity, Female, Humans, Male, Cardiomyopathies, Risk Factors, Sex Factors, World Health Organization
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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