The DOI matches its Crossref record; 125 of the 127 references it cites were found in a registry or an index.
Oligosaccharides from land plants and algae: production and applications in therapeutics and biotechnology
Abstract
Since the past decades, oligosaccharides are considered for their potential biological activities. To exploit them, it was essential to obtain pure molecules in large amounts. Several strategies were developed to produce specific sugar sequences with specific substitution patterns from land plants and algae polysaccharides. Then, pure oligosaccharides were analyzed for their potential biological activities and relations between oligomers structure and function were tackled. First they can be health beneficial molecules when they are added to the diet to enhance the growth of probiotic bacteria, in that case, oligomers that resist to the digestive process are used as specific substrate for the growth of health beneficial bacteria. In other cases, oligomers have to interact with receptors on cells. In this instance, a specific conformation is needed to allow the sugar sequence to establish specific linkages with the receptor. So, to be adapted to the receptor, the oligosaccharides have to present specific groups to the receptor, there, the polymerization degree of oligosaccharides as well as the flexibility of the glycosidic linkages has to be considered.
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“Some prebiotics (or prebiotic candidates) naturally occurring in seaweeds are saccharides presenting a degree of polymerization (DP) within 2 and 9 (sometimes within 8 and 20). Some researchers consider up to 25 sugar residues [122].”
From The Potential of Seaweeds as a Source of Functional Ingredients of Prebiotic and Antioxidant Value (2019) · cites this paper as [122]
In the citing paper
“The use of free radicals is another effective technique for the hydrolysis of polysaccharides, since it does not affect the structure of the compounds when it is correctly performed [122].”
From The Potential of Seaweeds as a Source of Functional Ingredients of Prebiotic and Antioxidant Value (2019) · cites this paper as [122]
In the citing paper
“phosphoric acid is capable of effectively hydrolyzing polysaccharides of some algae species, such as Chlorella vulgaris and Spirulina platensis [128], mostly composed of uronic acids and giving rise to interesting oligosaccharides with potential prebiotic properties [122].”
From The Potential of Seaweeds as a Source of Functional Ingredients of Prebiotic and Antioxidant Value (2019) · cites this paper as [122]
Citations
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Cited by
Sorted by citations
Algae as nutritional and functional food sources: revisiting our understanding.
Wells, M. L., Potin, P., Craigie, J. S., Raven, J. A., Merchant, S. S., Helliwell, K. E., Smith, A. G., Camire, M. E., & Brawley, S. H. (2017) · Journal of Applied Phycology · doi:10.1007/s10811-016-0974-5 · Cited by 1,562
Lordan, S., Ross, R. P., & Stanton, C. (2011) · Marine Drugs · doi:10.3390/md9061056 · Cited by 779
Shukla, P. S., Mantin, E. G., Adil, M., Bajpai, S., Critchley, A. T., & Prithiviraj, B. (2019) · Frontiers in Plant Science · doi:10.3389/fpls.2019.00655 · Cited by 630
Prebiotics from marine macroalgae for human and animal health applications
O’Sullivan, L., Murphy, B., McLoughlin, P., Duggan, P., Lawlor, P. G., Hughes, H., & Gardiner, G. E. (2010) · Marine Drugs · doi:10.3390/md8072038 · Cited by 421
Emergent Sources of Prebiotics: Seaweeds and Microalgae
De Jesus Raposo, M., De Morais, A., & De Morais, R. (2016) · Marine Drugs · doi:10.3390/md14020027 · Cited by 331
Metadata
- Authors
- Courtois, J.
- Affiliations
- Université de Picardie Jules Verne (FR)
- Corresponding author
- Courtois, Josiane
- Venue
- Current Opinion in Microbiology
- Publisher
- Elsevier BV
- Published
- 2009-06
- Volume
- 12
- Issue
- 3
- Pages
- 261-273
- ISSN
- 1369-5274 (ISSN-L)
- OpenAlex
- W2014100699
- Cited by
- 176
- References
- 127
- Citations by year
- 2026: 5 · 2025: 3 · 2024: 10 · 2023: 16 · 2022: 10 · 2021: 9 · 2020: 17 · 2019: 7 · 2018: 12 · 2017: 13 · 2016: 15 · 2015: 17 · 2014: 9 · 2013: 10 · 2012: 10
- FWCI
- 0.87
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Current Opinion in Microbiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Microbial Metabolites in Food Biotechnology
- Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Polysaccharides and Plant Cell Walls
- Keywords
- oligosaccharides, land plants, algae, polysaccharide degradation, oligosaccharide production, structure-function relationship, probiotic bacteria, prebiotics, receptor binding, degree of polymerization, therapeutics, biotechnology
- MeSH terms
- Biotechnology, Humans, Oligosaccharides, Plants, Therapeutics, Eukaryota
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