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Higher‐order oligomerization promotes localization of SPOP to liquid nuclear speckles

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Androgen Receptor Is the Key Transcriptional Mediator of the Tumor Suppressor SPOP in Prostate Cancer

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MATH/BTB CRL3 Receptors Target the Homeodomain-Leucine Zipper ATHB6 to Modulate Abscisic Acid Signaling

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Evidence for Molecular Differences in Prostate Cancer between African American and Caucasian Men

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Truncated ERG Oncoproteins from TMPRSS2-ERG Fusions Are Resistant to SPOP-Mediated Proteasome Degradation

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TRIM28 protects TRIM24 from SPOP-mediated degradation and promotes prostate cancer progression

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Stabilizing mutations of KLHL24 ubiquitin ligase cause loss of keratin 14 and human skin fragility

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Absolute Amounts and Status of the Nrf2-Keap1-Cul3 Complex within Cells

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Sequence-based drug design as a concept in computational drug design

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Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

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SPOP regulates prostate epithelial cell proliferation and promotes ubiquitination and turnover of c-MYC oncoprotein

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Prostate Cancer-associated SPOP mutations enhance cancer cell survival and docetaxel resistance by upregulating Caprin1-dependent stress granule assembly

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Exome sequencing of hepatoblastoma reveals novel mutations and cancer genes in the Wnt pathway and ubiquitin ligase complex

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Survey of the 2009 commercial optical biosensor literature

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ILF3 is a substrate of SPOP for regulating serine biosynthesis in colorectal cancer

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Succination of Keap1 and Activation of Nrf2-Dependent Antioxidant Pathways in FH-Deficient Papillary Renal Cell Carcinoma Type 2

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The diverse roles of SPOP in prostate cancer and kidney cancer

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Dominant Noonan syndrome-causing LZTR1 mutations specifically affect the Kelch domain substrate-recognition surface and enhance RAS-MAPK signaling

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Aberrant phase separation and cancer

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Time-resolved Global and Chromatin Proteomics during Herpes Simplex Virus Type 1 (HSV-1) Infection

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Ubiquitin–proteasome system and the role of its inhibitors in cancer therapy

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Post-Translational Modifications of H2A Histone Variants and Their Role in Cancer

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Recognition of the Diglycine C-End Degron by CRL2KLHDC2 Ubiquitin Ligase

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The emerging role of speckle-type POZ protein (SPOP) in cancer development

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Small-Molecule Targeting of E3 Ligase Adaptor SPOP in Kidney Cancer

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SPOP mutations promote p62/SQSTM1-dependent autophagy and Nrf2 activation in prostate cancer

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Fbw7 dimerization determines the specificity and robustness of substrate degradationPreprint

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The novel BET‐CBP/p300 dual inhibitor NEO2734 is active in SPOP mutant and wild‐type prostate cancer

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CUL3-KBTBD6/KBTBD7 Ubiquitin Ligase Cooperates with GABARAP Proteins to Spatially Restrict TIAM1-RAC1 Signaling

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GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme

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SPOP-mediated ubiquitination and degradation of PDK1 suppresses AKT kinase activity and oncogenic functions

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CUL3 E3 ligases in plant development and environmental response

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AMPK Promotes SPOP-Mediated NANOG Degradation to Regulate Prostate Cancer Cell Stemness

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Dimerization quality control ensures neuronal development and survival

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Dysregulation of INF2-mediated mitochondrial fission in SPOP-mutated prostate cancer

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SPOP-containing complex regulates SETD2 stability and H3K36me3-coupled alternative splicing

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Functional analysis of Cullin 3 E3 ligases in tumorigenesis

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Neddylation inhibition induces glutamine uptake and metabolism by targeting CRL3SPOP E3 ligase in cancer cells

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1Department of Structural Biology

Ligases, O. B.-C. U., Miller, D. J., Walden, H., Duda, D. M., Seyedin, S. N., Hoggard, T., Harper, J. W., White, K. P., & Schulman, B. A. (2015)

Insights into BTB-Cul3 Ubiquitin Ligases from the Structures of SPOP-Substrate Complexes

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Structural basis of high-order oligomerization of the cullin-3 adaptor SPOP

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