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Structure of the CRISPR Interference Complex CSM Reveals Key Similarities with Cascade
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Type III-A and type III-B share the signature protein Cas10 and are unique in relation to other interference mechanisms because they target both RNA and DNA substrates.
“Type III-A and type III-B share in common the signature protein of type III systems, Cas10, and are unique in relation to other interference mechanisms because they target both RNA and DNA substrates [48,49].”
From CRISPR-Cas: Converting A Bacterial Defence Mechanism into A State-of-the-Art Genetic Manipulation Tool (2019) · cites this paper as [48]
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Metadata
- Authors
- Rouillon, C., Zhou, M., Zhang, J., Politis, A., Beilsten-Edmands, V., Cannone, G., Graham, S., Robinson, C. V., Spagnolo, L., & White, M. F.
- Venue
- Molecular Cell
- Publisher
- Elsevier BV
- Published
- 2013-10
- Volume
- 52
- Issue
- 1
- Pages
- 124-134
- ISSN
- 1097-2765
- PMC
- PMC3807668
- Cited by
- 188
- References
- 0
- Language
- en
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