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Structure of the CRISPR Interference Complex CSM Reveals Key Similarities with Cascade

Rouillon, Christophe, Zhou, Min, Zhang, Jing, Politis, Argyris, Beilsten-Edmands, Victoria, Cannone, Giuseppe, Graham, Shirley, Robinson, Carol V., Spagnolo, Laura, White, Malcolm F.·2013·Molecular Cell

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  • Type III-A and type III-B share the signature protein Cas10 and are unique in relation to other interference mechanisms because they target both RNA and DNA substrates.

    “Type III-A and type III-B share in common the signature protein of type III systems, Cas10, and are unique in relation to other interference mechanisms because they target both RNA and DNA substrates [48,49].”

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Metadata

Authors
Rouillon, C., Zhou, M., Zhang, J., Politis, A., Beilsten-Edmands, V., Cannone, G., Graham, S., Robinson, C. V., Spagnolo, L., & White, M. F.
Venue
Molecular Cell
Publisher
Elsevier BV
Published
2013-10
Volume
52
Issue
1
Pages
124-134
ISSN
1097-2765
Cited by
188
References
0
Language
en

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