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5mC Oxidation by Tet2 Modulates Enhancer Activity and Timing of Transcriptome Reprogramming during Differentiation
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“The more-open chromatin state agrees well with the previously reported global DNA hypomethylation caused by TET2 deficiency26 (Extended Data Fig. 1f) but is inconsistent with a predominant DNA 5mC oxidation function.”
From RNA m5C oxidation by TET2 regulates chromatin state and leukaemogenesis (2024) · cites this paper as [26]
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Cites
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InfluentialTet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
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InfluentialSelf-citationCharting a dynamic DNA methylation landscape of the human genome
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Loss of Tet Enzymes Compromises Proper Differentiation of Embryonic Stem Cells
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Metadata
- Authors
- Hon, G. C., Song, C.-X., Du, T., Jin, F., Selvaraj, S., Lee, A. Y., Yen, C.-A., Ye, Z., Mao, S.-Q., Wang, B.-A., Kuan, S., Edsall, L. E., Zhao, B. S., Xu, G.-L., He, C., & Ren, B.
- Venue
- Molecular Cell
- Publisher
- Elsevier BV
- Published
- 2014-10
- Volume
- 56
- Issue
- 2
- Pages
- 286-297
- ISSN
- 1097-2765
- PMC
- PMC4319980
- Cited by
- 344
- References
- 19
- Language
- en
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