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Recent advancements in nanotechnological strategies in selection, design and delivery of biomolecules for skin regeneration
Abstract
Skin is a very complex organ and hence designing a bioengineered skin model replicating the essential physiological characteristics for replacing the diseased or damaged parts has been a challenging goal for many. Newer technologies for satisfying most of the criteria are being attempted with the copious efforts of biologists, engineers, physiologists, using multitude of features in combination. Amongst them nanotechnology based biomaterials have gained prominence owing to the enhanced pharmacokinetics, bio-distribution profile, extended half-life and reduced side effects. Designing a matrix that can be assimilated into the body during the regeneration and delivering the essential pharmacological agents in a temporal and spatially specific manner is a tremendous goal. This review essentially deals with the various approaches for designing a multidisciplinary translational smart matrix for addressing the various skin related ailments.
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“Generally, hydrophilic small drugs prefer paracellular routes, while hydrophobic drug molecules prefer to be absorbed via transcellular routes.98,99”
From Current Advances in Chitosan Nanoparticles Based Oral Drug Delivery for Colorectal Cancer Treatment (2022) · cites this paper as [98]
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Current Advances in Chitosan Nanoparticles Based Oral Drug Delivery for Colorectal Cancer Treatment
Choukaife, H., Seyam, S., Alallam, B., Doolaanea, A. A., & Alfatama, M. (2022) · International Journal of Nanomedicine · doi:10.2147/ijn.s375229 · Cited by 127
Metadata
- Authors
- Korrapati, P. S., Karthikeyan, K., Satish, A., Krishnaswamy, V. R., Venugopal, J. R., & Ramakrishna, S.
- Venue
- Materials Science and Engineering: C
- Publisher
- Elsevier BV
- Published
- 2016-10
- Volume
- 67
- Pages
- 747-765
- ISSN
- 0928-4931
- Cited by
- 102
- References
- 7
- Language
- en
- Update notices
- erratum (2016-11-01)
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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