Review on the role of hippocampus in autism spectrum disorder: recent insights into neuropathology, genetics, and emerging therapeutic strategies

Global prevalence of autism: A systematic review update

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Synaptic, transcriptional and chromatin genes disrupted in autism

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Prevalence and Characteristics of Autism Spectrum Disorder Among Children Aged 8 Years — Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2020

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Autism

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Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism

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Neuroglial activation and neuroinflammation in the brain of patients with autism

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De novo mutations revealed by whole-exome sequencing are strongly associated with autism

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FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism

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Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism

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Human emotion and memory: Interactions of the amygdala and hippocampal complex

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Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits

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Early brain development in infants at high risk for autism spectrum disorder

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Fmr1 knockout mice: A model to study fragile X mental retardation

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Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits

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Excitatory/Inhibitory Balance and Circuit Homeostasis in Autism Spectrum Disorders

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The hippocampal CA2 region is essential for social memory

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Birth defects after maternal exposure to corticosteroids: Prospective cohort study and meta-analysis of epidemiological studies

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Neuroanatomic observations of the brain in autism: a review and future directions

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Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice

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Coherent theta oscillations and reorganization of spike timing in the hippocampal- prefrontal network upon learning

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Prefrontal–hippocampal interactions in episodic memory

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Neuron Number and Size in Prefrontal Cortex of Children With Autism

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Microglial Activation and Increased Microglial Density Observed in the Dorsolateral Prefrontal Cortex in Autism

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Action potential generation requires a high sodium channel density in the axon initial segment

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Hippocampal–prefrontal input supports spatial encoding in working memory

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Common circuit defect of excitatory-inhibitory balance in mouse models of autism

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Mutations causing syndromic autism define an axis of synaptic pathophysiology

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The serotonin system in autism spectrum disorder: From biomarker to animal models

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Microglial Activation in Young Adults With Autism Spectrum Disorder

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Amygdala inputs to the ventral hippocampus bidirectionally modulate social behavior

Felix-Ortiz, A. C., & Tye, K. M. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.4257-13.2014 · Cited by 473 · see citing works

Zscan4 regulates telomere elongation and genomic stability in ES cells

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The influence of neuroinflammation in Autism Spectrum Disorder

Matta, S. M., Hill‐Yardin, E. L., & Crack, P. J. (2019) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2019.04.037 · Cited by 414 · see citing works

Maternal periconceptional folic acid intake and risk of autism spectrum disorders and developmental delay in the CHARGE (CHildhood Autism Risks from Genetics and Environment) case-control study

Schmidt, R. J., Tancredi, D. J., Ozonoff, S., Hansen, R. L., Hartiala, J., Allayee, H., Schmidt, L. C., Tassone, F., & Hertz-Picciotto, I. (2012) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.110.004416 · Cited by 408 · see citing works

Altered cerebellar connectivity in autism and cerebellar-mediated rescue of autism-related behaviors in mice

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Pathogenic SYNGAP1 Mutations Impair Cognitive Development by Disrupting Maturation of Dendritic Spine Synapses

Clement, J. P., Aceti, M., Creson, T. K., Ozkan, E. D., Shi, Y., Reish, N. J., Almonte, A. G., Miller, B. H., Wiltgen, B. J., Miller, C. A., et al. (2012) · Cell · doi:10.1016/j.cell.2012.08.045 · Cited by 385 · see citing works

AnkyrinG is required for maintenance of the axon initial segment and neuronal polarity

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CHD8 haploinsufficiency results in autistic-like phenotypes in mice

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Intranasal oxytocin versus placebo in the treatment of adults with Autism Spectrum Disorders: A randomized controlled trial

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Translating Dosage Compensation to Trisomy 21

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Homozygous HOXA1 mutations disrupt human brainstem, inner ear, cardiovascular and cognitive development

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Safety and efficacy of cognitive training plus epigallocatechin-3-gallate in young adults with Down's syndrome (TESDAD): a double-blind, randomised, placebo-controlled, phase 2 trial

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Truncating mutations in NRXN2 and NRXN1 in autism spectrum disorders and schizophrenia

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Loss of Predominant Shank3 Isoforms Results in Hippocampus-Dependent Impairments in Behavior and Synaptic Transmission

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Epigallocatechin‐3‐gallate, a DYRK1A inhibitor, rescues cognitive deficits in D own syndrome mouse models and in humans

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Dysregulation and restoration of translational homeostasis in fragile X syndrome

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Innate immune dysfunction and neuroinflammation in autism spectrum disorder (ASD)

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Effects of Lactobacillus plantarum PS128 on Children with Autism Spectrum Disorder in Taiwan: A Randomized, Double-Blind, Placebo-Controlled Trial

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Exome sequencing of 457 autism families recruited online provides evidence for autism risk genes

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Serotonin facilitates GABAergic transmission in the CA1 region of rat hippocampus in vitro.

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The physiology of the axon initial segment

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Maternal Loss of Ube3a Produces an Excitatory/Inhibitory Imbalance through Neuron Type-Specific Synaptic Defects

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Decreased GABAA receptors and benzodiazepine binding sites in the anterior cingulate cortex in autism

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Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain

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Chromatin accessibility: biological functions, molecular mechanisms and therapeutic application

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Progress and roadblocks in the search for brain-based biomarkers of autism and attention-deficit/hyperactivity disorder

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Prediction in autism spectrum disorder: A systematic review of empirical evidence

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Association between the oxytocin receptor gene and amygdalar volume in healthy adults

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Salience Network Connectivity in Autism Is Related to Brain and Behavioral Markers of Sensory Overresponsivity

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Clinically Significant Anxiety in Children with Autism Spectrum Disorder and Varied Intellectual Functioning

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A Diffusion Tensor Imaging Study in Children With ADHD, Autism Spectrum Disorder, OCD, and Matched Controls: Distinct and Non-Distinct White Matter Disruption and Dimensional Brain-Behavior Relationships

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Mutations in Prickle Orthologs Cause Seizures in Flies, Mice, and Humans

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Bisphenol A Exposure in Children With Autism Spectrum Disorders

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mTOR-related synaptic pathology causes autism spectrum disorder-associated functional hyperconnectivity

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The neuropathology of autism: A systematic review of post-mortem studies of autism and related disorders

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Sonic Hedgehog Signaling and Hippocampal Neuroplasticity

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Behavioral and Neuroanatomical Phenotypes in Mouse Models of Autism

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The Calsyntenins—A Family of Postsynaptic Membrane Proteins with Distinct Neuronal Expression Patterns

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The global prevalence of autism spectrum disorder in children: a systematic review and meta-analysis

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Reconsidering animal models used to study autism spectrum disorder: Current state and optimizing future

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Decreased GAD65 mRNA levels in select subpopulations of neurons in the cerebellar dentate nuclei in autism: an in situ hybridization study

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DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity

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Mice with reduced NMDA receptor expression: more consistent with autism than schizophrenia?

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SYNGAP1: Mind the Gap

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Differential Local Connectivity and Neuroinflammation Profiles in the Medial Prefrontal Cortex and Hippocampus in the Valproic Acid Rat Model of Autism

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Risk of Autism after Prenatal Topiramate, Valproate, or Lamotrigine Exposure

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Relationship Between Sonic Hedgehog Protein, Brain-Derived Neurotrophic Factor and Oxidative Stress in Autism Spectrum Disorders

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Mapping axon initial segment structure and function by multiplexed proximity biotinylation

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Non-synaptic function of the autism spectrum disorder-associated gene SYNGAP1 in cortical neurogenesis

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HippoBellum: Acute Cerebellar Modulation Alters Hippocampal Dynamics and Function

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Disruption of the non-canonical Wnt gene PRICKLE2 leads to autism-like behaviors with evidence for hippocampal synaptic dysfunction

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Rescue of maternal immune activation-induced behavioral abnormalities in adult mouse offspring by pathogen-activated maternal Treg cells

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Social Deficits and Cerebellar Degeneration in Purkinje Cell Scn8a Knockout Mice

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Single-nucleotide polymorphism analysis accurately predicts multiple impairments in hippocampal activity and memory performance in a murine model of idiopathic autism

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White-Matter fiber tract and resting-state functional connectivity abnormalities in young children with autism spectrum disorder

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Arg209Lys and Gln508His missense variants in Rabphilin 3A cause pre- and post-synaptic dysfunctions at excitatory glutamatergic synapses

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Calcitriol Modulates Hippocampal Axon Guidance Through Enhanced EfnA4 ‐Mediated PI3K / AKT Signaling in an Autism Mouse Model

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Diffusion trajectory of atypical morphological development in autism spectrum disorder

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Genetic machinery which accompanies metaplasticity operates differentially in experimental model of autism

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Lean-NET-Based Local Brain Connectome Analysis for Autism Spectrum Disorder Classification

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Alterations in Amygdala and Hippocampal Volumes in Autism Spectrum Disorder: Meta-analysis

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P-Rex Rac-GEFs

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Decomposing the genetic risk of autism spectrum disorder into discrete molecular subtypes underlie clinical heterogeneity based on transcriptome profile

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Trigonelline attenuates valproic acid-induced autism-like behaviours in rats: histopathological changes of the hippocampus, modulation of gene expressions related to neuroinflammation and blood-brain barrier permeability

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Effects of hydroethanolic extract of Crassocephalum crepidioides leaves on a mouse model of fetal alcohol-related behavioral and neurobiological alterations induced by prenatal ethanol exposure

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The molecular footprint of valproic acid in human hippocampal organoid

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Insights into the structure and function of the hippocampus: implications for the pathophysiology and treatment of autism spectrum disorder

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