Defining the behavioral phenotype in children with fetal alcohol spectrum disorders: A review

Kodituwakku, P.W.

doi:10.1016/j.neubiorev.2006.06.020

Cited by 359Prenatal Substance Exposure EffectsSubstance Abuse Treatment and OutcomesFetal and Pediatric Neurological Disorders

Defining the behavioral phenotype in children with fetal alcohol spectrum disorders: A review

Kodituwakku, P.W.·2007·Neuroscience & Biobehavioral Reviews

DOI 10.1016/j.neubiorev.2006.06.020

Open this paper in CoChat — free account

Abstract

While there exists a large body of literature on cognitive functions in children with prenatal alcohol exposure, it remains undetermined if these children exhibit a unique profile of cognitive-behavioral functioning or a behavioral phenotype. Researchers have consistently found that intellectual functioning, as assessed by IQ tests, of children with prenatal alcohol exposure is deficient. There is increasing evidence that prenatal alcohol exposure is associated with slow information processing and attentional problems, in particular inattentiveness. Studies examining specific cognitive abilities such as language, visual perception, and memory in alcohol-affected children have shown performance decrements associated with increased task complexity. Children with prenatal alcohol exposure have also been found to exhibit significant deficits in daily functional skills or adaptive behavior, with deficits in socialization becoming pronounced during adolescence. The above findings point to the conclusion that a generalized deficit in complex information processing constitutes the central cognitive-behavioral characteristic of children with prenatal alcohol exposure. Researchers have consistently documented that specific brain regions are more affected by alcohol than other regions. The problem of mapping focal anomalies of the brain with a generalized pattern of deficits can be solved by taking developmental processes into consideration.

Integrity signals

Registry

Crossref · 10.1016/j.neubiorev.2006.06.020

Cites

93 of 93 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Some of the key deficits in children with fetal alcohol spectrum disorders are in the domains of attention, information processing, and executive function.
“It has been established that some of the key deficits in children are in the domains of attention, information processing, and executive function (EF) [6].”
From Evaluation of a Custom-Developed Computer Game to Improve Executive Functioning in 4- to 6-Year-Old Children Exposed to Alcohol in Utero: Protocol for a Feasibility Randomized Controlled Trial (2019) · cites this paper as [6]

Untitled work
(1994) · DigitalGeorgetown (Georgetown University Library) · Cited by 10,542 · see citing works
Insensitivity to future consequences following damage to human prefrontal cortex
Bechara, A., Damasio, A. R., Damasio, H., & Anderson, S. W. (1994) · Cognition · doi:10.1016/0010-0277(94)90018-3 · Cited by 6,128 · see citing works
Descartes’ Error. Emotion, Reason and the Human Brain. New York (Grosset/Putnam) 1994.
Damasio, A. R. (1994) · Cited by 2,266 · see citing works
Risk Factors for Adverse Life Outcomes in Fetal Alcohol Syndrome and Fetal Alcohol Effects
STREISSGUTH, A. P., BOOKSTEIN, F. L., BARR, H. M., SAMPSON, P. D., O'MALLEY, K., & YOUNG, J. K. (2004) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/00004703-200408000-00002 · Cited by 1,195 · see citing works
Clinics in Developmental Medicine
Humphreys, P. (2013) · Elsevier eBooks · doi:10.1016/b978-1-4831-9649-7.50021-9 · Cited by 1,146 · see citing works
Emotion-related learning in patients with social and emotional changes associated with frontal lobe damage.
Rolls, E. T., Hornak, J., Wade, D., & McGrath, J. (1994) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.57.12.1518 · Cited by 1,005 · see citing works
Fetal alcohol syndrome: diagnosis, epidemiology, prevention, and treatment
(1997) · Choice Reviews Online · doi:10.5860/choice.34-2779 · Cited by 918 · see citing works
Analysis of the elements of attention: A neuropsychological approach
Mirsky, A. F., Anthony, B. J., Duncan, C. C., Ahearn, M. B., & Kellam, S. G. (1991) · Neuropsychology Review · doi:10.1007/bf01109051 · Cited by 874 · see citing works
A Review of the Neurobehavioral Deficits in Children with Fetal Alcohol Syndrome or Prenatal Exposure to Alcohol
Mattson, S. N., & Riley, E. P. (1998) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1998.tb03651.x · Cited by 608 · see citing works
Dissociating executive functions of the prefrontal cortex.
Robbins, T. W. (1996) · Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rstb.1996.0131 · Cited by 574 · see citing works
Moderate Prenatal Alcohol Exposure: Effects on Child IQ and Learning Problems at Age 7 1/2 Years
Streissguth, A. P., Barr, H. M., & Sampson, P. D. (1990) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1990.tb01224.x · Cited by 547 · see citing works
Brain dysmorphology in individuals with severe prenatal alcohol exposure
Archibald, S. L., Fennema‐Notestine, C., Gamst, A. C., Riley, E. P., Mattson, S. N., & Jernigan, T. L. (2001) · Developmental Medicine & Child Neurology · doi:10.1111/j.1469-8749.2001.tb00179.x · Cited by 510 · see citing works
A Review of the Neurobehavioral Deficits in Children with Fetal Alcohol Syndrome or Prenatal Exposure to Alcohol
Mattson, S. N., & Riley, E. P. (1998) · Alcoholism Clinical and Experimental Research · doi:10.1097/00000374-199804000-00001 · Cited by 486 · see citing works
Neuropsychiatric implications and long-term consequences of fetal alcohol spectrum disorders
Streissguth, A. P., & O’Malley, K. D. (2000) · Seminars in Clinical Neuropsychiatry · doi:10.1053/scnp.2000.6729 · Cited by 466 · see citing works
A Comparison of Children Affected by Prenatal Alcohol Exposure and Attention Deficit, Hyperactivity Disorder
Coles, C. D., Platzman, K. A., Raskind‐Hood, C. L., Brown, R. T., Falek, A., & Smith, I. E. (1997) · Alcoholism: Clinical and Experimental Research · doi:10.1111/j.1530-0277.1997.tb03743.x · Cited by 443 · see citing works
Executive Functioning and Working Memory in Fetal Alcohol Spectrum Disorder
Rasmussen, C. (2005) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000175040.91007.d0 · Cited by 374 · see citing works
Executive Functioning in Children With Heavy Prenatal Alcohol Exposure
Mattson, S. N., Goodman, A. M., Caine, C., Delis, D. C., & Riley, E. P. (1999) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1999.tb04077.x · Cited by 374 · see citing works
Neuropsychological comparison of alcohol-exposed children with or without physical features of fetal alcohol syndrome.
Mattson, S. N., Riley, E. P., Gramling, L., Delis, D. C., & Jones, K. L. (1998) · Neuropsychology · doi:10.1037//0894-4105.12.1.146 · Cited by 351 · see citing works
Neuropsychological Deficits in Adolescents with Fetal Alcohol Syndrome: Clinical Findings
Olson, H. C., Feldman, J. J., Streissguth, A. P., Sampson, P. D., & Bookstein, F. L. (1998) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1998.tb05909.x · Cited by 320 · see citing works
Effects of prenatal alcohol exposure at school age. I. Physical and cognitive development
Coles, C. D., Brown, R. T., Smith, I. E., Platzman, K. A., Erickson, S., & Falek, A. (1991) · Neurotoxicology and Teratology · doi:10.1016/0892-0362(91)90084-a · Cited by 314 · see citing works
Corpus Callosum Shape and Neuropsychological Deficits in Adult Males with Heavy Fetal Alcohol Exposure
Bookstein, F. L., Streissguth, A. P., Sampson, P. D., Connor, P. D., & Barr, H. M. (2002) · NeuroImage · doi:10.1006/nimg.2001.0977 · Cited by 309 · see citing works
Direct and Indirect Effects of Prenatal Alcohol Damage on Executive Function
Connor, P. D., Sampson, P. D., Bookstein, F. L., Barr, H. M., & Streissguth, A. P. (2000) · Developmental Neuropsychology · doi:10.1207/s1532694204connor · Cited by 303 · see citing works
Heavy prenatal alcohol exposure with or without physical features of fetal alcohol syndrome leads to IQ deficits
Mattson, S. N., Riley, E. P., Gramling, L., Delis, D. C., & Jones, K. L. (1997) · The Journal of Pediatrics · doi:10.1016/s0022-3476(97)70099-4 · Cited by 282 · see citing works
Attention Deficits in Children Exposed to Alcohol Prenatally
Nanson, J. L., & Hiscock, M. (1990) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1990.tb01223.x · Cited by 278 · see citing works
Intelligence, behavior, and dysmorphogenesis in the fetal alcohol syndrome: A report on 20 patients
Streissguth, A. P., Herman, C. S., & Smith, D. W. (1978) · The Journal of Pediatrics · doi:10.1016/s0022-3476(78)80420-x · Cited by 275 · see citing works
Comparison of Social Abilities of Children with Fetal Alcohol Syndrome to Those of Children with Similar IQ Scores and Normal Controls
Thomas, S. E., Kelly, S. J., Mattson, S. N., & Riley, E. P. (1998) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1998.tb03684.x · Cited by 270 · see citing works
Neuropsychological comparison of alcohol-exposed children with or without physical features of fetal alcohol syndrome.
Mattson, S. N., Riley, E. P., Gramling, L., et al. (1998) · Neuropsychology · doi:10.1037/0894-4105.12.1.146 · Cited by 267 · see citing works
Are developmental disorders like cases of adult brain damage? Implications from connectionist modelling
Thomas, M. S. C., & Karmiloff‐Smith, A. (2002) · Behavioral and Brain Sciences · doi:10.1017/s0140525x02000134 · Cited by 266 · see citing works
Mapping callosal morphology and cognitive correlates
Sowell, E. R., Mattson, S. N., Thompson, P. M., Jernigan, T. L., Riley, E. P., & Toga, A. W. (2001) · Neurology · doi:10.1212/wnl.57.2.235 · Cited by 254 · see citing works
Specific Impairments in Self‐Regulation in Children Exposed to Alcohol Prenatally
Kodituwakku, P. W., Handmaker, N. S., Cutler, S. K., Weathersby, E. K., & Handmaker, S. D. (1995) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1995.tb01024.x · Cited by 253 · see citing works
Self-citation
60??? and 72-Month Follow-up of Children Prenatally Exposed to Marijuana, Cigarettes, and Alcohol
Fried, P. A., CONNELL, C. M. O., & Watkinson, B. (1992) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/00004703-199212000-00001 · Cited by 251 · see citing works
Regional Brain Shape Abnormalities Persist into Adolescence after Heavy Prenatal Alcohol Exposure
Sowell, E. R. (2002) · Cerebral Cortex · doi:10.1093/cercor/12.8.856 · Cited by 244 · see citing works
Abnormal Development of the Cerebellar Vermis in Children Prenatally Exposed to Alcohol: Size Reduction in Lobules I–V
Sowell, E. R., Jernigan, T. L., Mattson, S. N., Riley, E. P., Sobel, D. F., & Jones, K. L. (1996) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1996.tb01039.x · Cited by 241 · see citing works
Population-based case-control study of teratogenic potential of corticosteroids.
Czeizel, A., & Rockenbauer, M. (1997) · Teratology · doi:10.1002/(sici)1096-9926(199711)56:5 · Cited by 235 · see citing works
Children with Fetal Alcohol Syndrome are impaired at place learning but not cued-navigation in a virtual Morris water task
Hamilton, D. A., Kodituwakku, P. W., Sutherland, R. J., & Savage, D. D. (2003) · Behavioural Brain Research · doi:10.1016/s0166-4328(03)00028-7 · Cited by 232 · see citing works
Self-citation
Verbal Learning and Memory in Children with Fetal Alcohol Syndrome
Mattson, S. N., Riley, E. P., Delis, D. C., Stern, C., & Jones, K. L. (1996) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1996.tb05256.x · Cited by 228 · see citing works
Attention, distraction and reaction time at age 7 years and prenatal alcohol exposure.
Streissguth, A. P., Barr, H. M., Sampson, P. D., Parrish-Johnson, J. C., Kirchner, G. L., & Martin, D. C. (1986) · PubMed · Cited by 217 · see citing works
Spatial locations gone awry: Object and spatial memory deficits in children with fetal alcohol syndrome
Uecker, A., & Nadel, L. (1996) · Neuropsychologia · doi:10.1016/0028-3932(95)00096-8 · Cited by 212 · see citing works
Voxel-based morphometric analyses of the brain in children and adolescents prenatally exposed to alcohol
Sowell, E. R., Thompson, P. M., Mattson, S. N., Tessner, K. D., Jernigan, T. L., Riley, E. P., & Toga, A. W. (2001) · Neuroreport · doi:10.1097/00001756-200103050-00018 · Cited by 198 · see citing works
IQ at age 4 in relation to maternal alcohol use and smoking during pregnancy.
Streissguth, A. P., Barr, H. M., Sampson, P. D., Darby, B. L., & al, E. (1989) · Developmental Psychology · doi:10.1037/0012-1649.25.1.3 · Cited by 192 · see citing works
Neuropsychological Deficits in Fetal Alcohol Syndrome and Fetal Alcohol Effects
Conry, J. (1990) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1990.tb01222.x · Cited by 186 · see citing works
Drinking During Pregnancy Decreases Word Attack and Arithmetic Scores on Standardized Tests: Adolescent Data From a Population‐Based Prospective Study
Streissguth, A. P., Barr, H. M., Olson, H. C., Sampson, P. D., Bookstein, F. L., & Burgess, D. M. (1994) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1994.tb00009.x · Cited by 183 · see citing works
Verbal and Visuospatial Learning and Memory Function in Children With Moderate Prenatal Alcohol Exposure
Willford, J. A., Richardson, G. A., Leech, S. L., & Day, N. L. (2004) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000117868.97486.2d · Cited by 181 · see citing works
Maternal alcohol use and neonatal habituation assessed with the Brazelton scale.
Streissguth, A. P., Barr, H. M., & Martin, D. C. (1983) · PubMed · Cited by 175 · see citing works
Cognitive Deficits in Nonretarded Adults with Fetal Alcohol Syndrome
Kerns, K. A., Don, A. J., Mateer, C. A., & Streissguth, A. P. (1997) · Journal of Learning Disabilities · doi:10.1177/002221949703000612 · Cited by 174 · see citing works
Psychiatric Illness in a Clinical Sample of Children with Prenatal Alcohol Exposure
O’Connor, M. J., Shah, B., Whaley, S. E., Cronin, P., Gunderson, B. H., & Graham, J. M. (2002) · The American Journal of Drug and Alcohol Abuse · doi:10.1081/ada-120015880 · Cited by 174 · see citing works
Relation of Maternal Age and Pattern of Pregnancy Drinking to Functionally Significant Cognitive Deficit in Infancy
Jacobson, J. L., Jacobson, S. W., Sokol, R. J., & Ager, J. W. (1998) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1998.tb03659.x · Cited by 171 · see citing works
Auditory and Visual Sustained Attention in Adolescents Prenatally Exposed to Alcohol
Coles, C. D., Platzman, K. A., Lynch, M. E., & Freides, D. (2002) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2002.tb02533.x · Cited by 168 · see citing works
Impairments of number processing induced by prenatal alcohol exposure
Kopera-Frye, K., Dehaene, S., & Streissguth, A. P. (1996) · Neuropsychologia · doi:10.1016/0028-3932(96)00043-7 · Cited by 162 · see citing works
Maternal Alcohol Use and Neonatal Habituation Assessed with the Brazelton Scale
Streissguth, A. P., Barr, H. M., & Martin, D. C. (1983) · Child Development · doi:10.2307/1129667 · Cited by 158 · see citing works
Comparison of the Adaptive Functioning of Children Prenatally Exposed to Alcohol to a Nonexposed Clinical Sample
Whaley, S. E., O'Connor, M. J., & Gunderson, B. H. (2001) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2001.tb02311.x · Cited by 157 · see citing works
Fetal Alcohol Syndrome: A Case Report of Neuropsychological, MRI, and EEG Assessment of Two Children
Mattson, S. N., Riley, E. P., Jernigan, T. L., Ehlers, C. L., Delis, D. C., Jones, K. L., Stern, C., Johnson, K. A., Hesselink, J. R., & Bellugi, U. (1992) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1992.tb01909.x · Cited by 156 · see citing works
Midline corpus callosum is a neuroanatomical focus of fetal alcohol damage
Bookstein, F. L., Sampson, P. D., Connor, P. D., & Streissguth, A. P. (2002) · The Anatomical Record · doi:10.1002/ar.10110 · Cited by 154 · see citing works
Geometric morphometrics of corpus callosum and subcortical structures in the fetal‐alcohol‐affected brain
Bookstein, F. L., Sampson, P. D., Streissguth, A. P., & Connor, P. D. (2001) · Teratology · doi:10.1002/tera.1044 · Cited by 154 · see citing works
Verbal and nonverbal fluency in children with heavy prenatal alcohol exposure.
Schonfeld, A. M., Mattson, S. N., Lang, A. R., Delis, D. C., & Riley, E. P. (2001) · Journal of Studies on Alcohol · doi:10.15288/jsa.2001.62.239 · Cited by 150 · see citing works
Relation of prenatal alcohol exposure to cognitive processing speed and efficiency in childhood.
Burden, M. J., Jacobson, S., & Jacobson, J. L. (2005) · Alcoholism: Clinical and Experimental Research · doi:10.1097/01.alc.0000175036.34076.a0 · Cited by 144 · see citing works
Acquisition and Retention of Verbal and Nonverbal Information in Children With Heavy Prenatal Alcohol Exposure
Mattson, S. N., & Roebuck, T. M. (2002) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2002.tb02617.x · Cited by 140 · see citing works
Relation of Maternal Age and Pattern of Pregnancy Drinking to Functionally Significant Cognitive Deficit in Infancy
Jacobson, J. L., Jacobson, S. W., Sokol, R. J., & Ager, J. W. (1998) · Alcoholism Clinical and Experimental Research · doi:10.1097/00000374-199804000-00009 · Cited by 139 · see citing works
Patterns of Cognitive-Motor Development in Children With Fetal Alcohol Syndrome From a Community in South Africa
Adnams, C. M., Kodituwakku, P. W., Hay, A., Molteno, C. D., Viljoen, D. L., & May, P. A. (2001) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2001.tb02250.x · Cited by 137 · see citing works
Self-citation
Mapping Cortical Gray Matter Asymmetry Patterns in Adolescents with Heavy Prenatal Alcohol Exposure
Sowell, E. R. (2002) · NeuroImage · doi:10.1006/nimg.2002.1328 · Cited by 137 · see citing works
Implicit and explicit memory functioning in children with heavy prenatal alcohol exposure
Mattson, S. N., & Riley, E. P. (1999) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617799555082 · Cited by 136 · see citing works
A Fetal Alcohol Behavior Scale
Streissguth, A. P., Bookstein, F. L., Barr, H. M., Press, S., & Sampson, P. D. (1998) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1998.tb03656.x · Cited by 127 · see citing works
Auditory and Visual Sustained Attention in Adolescents Prenatally Exposed to Alcohol
Coles, C. D., Platzman, K. A., Lynch, M. E., & Freides, D. (2002) · Alcoholism Clinical and Experimental Research · doi:10.1097/00000374-200202000-00015 · Cited by 127 · see citing works
Executive Functioning in Preschool-Age Children Prenatally Exposed to Alcohol, Cocaine, and Marijuana
Noland, J. S., Singer, L. T., Arendt, R. E., Minnes, S., Short, E. J., & Bearer, C. F. (2003) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000060525.10536.f6 · Cited by 113 · see citing works
Comparison of the Adaptive Functioning of Children Prenatally Exposed to Alcohol to a Nonexposed Clinical Sample
Whaley, S. E., Connor, M. J. O., & Gunderson, B. H. (2001) · Alcoholism Clinical and Experimental Research · doi:10.1097/00000374-200107000-00011 · Cited by 112 · see citing works
Hearing, Speech, Language, and Vestibular Disorders in the Fetal Alcohol Syndrome: A Literature Review
Church, M. W., & Kaltenbach, J. A. (1997) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1997.tb03796.x · Cited by 111 · see citing works
Specificity of Neurobehavioral Outcomes Associated with Prenatal Alcohol Exposure
Jacobson, S. W. (1998) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1998.tb03654.x · Cited by 103 · see citing works
Fetal alcohol syndrome: A description of oral motor, articulatory, short-term memory, grammatical, and semantic abilities
Becker, M., Warr-Leeper, G. A., & Leeper, H. A. (1990) · Journal of Communication Disorders · doi:10.1016/0021-9924(90)90016-r · Cited by 102 · see citing works
Developmental Neuropsychiatry.
Chun, R. W. M. (1998) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-199801000-00015 · Cited by 101 · see citing works
Emotion-related learning in individuals prenatally exposed to alcohol: an investigation of the relation between set shifting, extinction of responses, and behavior
Kodituwakku, P. W., May, P. A., Clericuzio, C. L., & Weers, D. C. (2001) · Neuropsychologia · doi:10.1016/s0028-3932(01)00002-1 · Cited by 100 · see citing works
Self-citation
Twelve year follow-up of children exposed to alcohol in utero
Autti‐Rämö, I. (2000) · Developmental Medicine & Child Neurology · doi:10.1017/s0012162200000748 · Cited by 92 · see citing works
Prenatal exposure to alcohol and school problems in late childhood: A longitudinal prospective study
Olson, H. C., Sampson, P. D., Barr, H. M., Streissguth, A. P., & Bookstein, F. L. (1992) · Development and Psychopathology · doi:10.1017/s0954579400000821 · Cited by 92 · see citing works
Executive Functioning in Preschool‐Age Children Prenatally Exposed to Alcohol, Cocaine, and Marijuana
Noland, J. S., Singer, L. T., Arendt, R. E., et al. (2003) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2003.tb04401.x · Cited by 86 · see citing works
Follow-Up Studies of Children with Fetal Alcohol Syndrome
Spohr, H. L., & Steinhausen, H. (1987) · Neuropediatrics · doi:10.1055/s-2008-1052428 · Cited by 82 · see citing works
Neurobehavioral Characteristics of Children with Fetal Alcohol Spectrum Disorders in Communities from Italy: Preliminary Results
Kodituwakku, P. W., Coriale, G., Fiorentino, D., Aragón, A. S., Kalberg, W. O., Buckley, D. G., Gossage, J. P., Ceccanti, M., & May, P. A. (2006) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2006.00187.x · Cited by 81 · see citing works
Self-citation
Prenatal Alcohol Exposure and Language Development
Greene, T., Emhart, C. B., Martier, S., Sokol, R., & Ager, J. (1990) · Alcoholism: Clinical and Experimental Research · doi:10.1111/j.1530-0277.1990.tb01842.x · Cited by 77 · see citing works
Classifying children with heavy prenatal alcohol exposure using measures of attention
LEE, K. T., Mattson, S. N., & Riley, E. P. (2004) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617704102142 · Cited by 73 · see citing works
Communication effects of prenatal alcohol exposure
Abkarian, G. G. (1992) · Journal of Communication Disorders · doi:10.1016/0021-9924(92)90017-q · Cited by 68 · see citing works
Neuropsychological Deficits in Adolescents with Fetal Alcohol Syndrome
Olson, H. C., Feldman, J. J., Streissguth, A. P., Sampson, P. D., & Bookstein, F. L. (1998) · Alcoholism Clinical and Experimental Research · doi:10.1097/00000374-199812000-00016 · Cited by 68 · see citing works
A Multiple-Level, Comprehensive Approach to the Prevention of Fetal Alcohol Syndrome (FAS) and Other Alcohol-Related Birth Defects (ARBD)
May, P. A. (1995) · International Journal of the Addictions · doi:10.3109/10826089509104417 · Cited by 65 · see citing works
Prenatal exposure to moderate levels of ethanol can have long-lasting effects on learning and memory in adult offspring
Sutherland, R. J., McDonald, R. J., & Savage, D. D. (2000) · Psychobiology · doi:10.3758/bf03332012 · Cited by 63 · see citing works
Perinatal substance abuse: Research findings and clinical implications
Lione, A. (1993) · Reproductive Toxicology · doi:10.1016/0890-6238(93)90276-d · Cited by 63 · see citing works
Letter and Category Fluency in Children With Fetal Alcohol Syndrome From a Community in South Africa
Kodituwakku, P. W., Adnams, C. M., Hay, A., Kitching, A. E., Burger, E., Kalberg, W. O., Viljoen, D. L., & May, P. A. (2006) · Journal of Studies on Alcohol · doi:10.15288/jsa.2006.67.502 · Cited by 63 · see citing works
Self-citation
Learning following prenatal alcohol exposure: performance on verbal and visual multitrial tasks
Kaemingk, K. L., Mulvaney, S. A., & Halverson, P. T. (2003) · Archives of Clinical Neuropsychology · doi:10.1093/arclin/18.1.33 · Cited by 60 · see citing works
Interhemispheric Transfer in Children with Heavy Prenatal Alcohol Exposure
Roebuck, T. M., Mattson, S. N., & Riley, E. P. (2002) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2002.tb02494.x · Cited by 58 · see citing works
Alcohol Use in Primiparous Women Older Than 30 Years of Age: Relation to Infant Development
O’Connor, M. J., Brill, N., & Sigman, M. (1986) · PEDIATRICS · doi:10.1542/peds.78.3.444 · Cited by 52 · see citing works
Fractionated Simple and Choice Reaction Time in Children with Prenatal Exposure to Alcohol
Simmons, R. W., Wass, T. S., Thomas, J. D., & Riley, E. P. (2002) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2002.tb02686.x · Cited by 49 · see citing works
Global — local processing in children prenatally exposed to alcohol
Mattson, S. N., Gramling, L., Riley, E. P., Delis, D. C., & Jones, K. L. (1996) · Child Neuropsychology · doi:10.1080/09297049608402249 · Cited by 49 · see citing works
Prenatal Alcohol Exposure and Development at Preschool Age: Main Results of a French Study
Larroque, B., & Kaminski, M. (1998) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1998.tb03652.x · Cited by 47 · see citing works
Perinatal substance abuse : research findings and clinical implications
Sonderegger, T. B. (1992) · Johns Hopkins University Press eBooks · Cited by 42 · see citing works
Condray, R., and Steinhauer, S.R. (2002). The residual normality assumption and models of cognition in schizophrenia. Commentary on M. Thomas and A. Karmiloff-Smith, "Are developmental disorders like cases of adult brain damage? Implications from connectionist modelling." Behavioral and Brain Sciences, 25:753-754. Title: The Residual Normality Assumption and Models of Cognition in Schizophrenia
Condray, R., & Steinhauer, S. R. (2002) · Cited by 16 · see citing works
The beauty of models for developmental disorders
Briscoe, J. (2002) · Behavioral and Brain Sciences · doi:10.1017/s0140525x02220130 · Cited by 1 · see citing works
Untitled work
(2000) · doi:10.1002/(sici)1098-1063(2000)10:1

Flagged first, then by citations

Sorted by citations

Fetal Alcohol Spectrum Disorders: Neuropsychological and Behavioral Features
Mattson, S. N., Crocker, N., & Nguyen, T. T. (2011) · Neuropsychology Review · doi:10.1007/s11065-011-9167-9 · Cited by 615 · see citing works
Prenatal alcohol exposure: Fetal programming and later life vulnerability to stress, depression and anxiety disorders
Hellemans, K. G. C., Sliwowska, J. H., Verma, P., & Weinberg, J. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2009.06.004 · Cited by 344 · see citing works
Misdiagnosis and Missed Diagnoses in Foster and Adopted Children With Prenatal Alcohol Exposure
Chasnoff, I. J., Wells, A. M., & King, L. (2015) · PEDIATRICS · doi:10.1542/peds.2014-2171 · Cited by 337 · see citing works
Prenatal Alcohol Exposure: Foetal Programming, the Hypothalamic‐Pituitary‐Adrenal Axis and Sex Differences in Outcome
Weinberg, J., Sliwowska, J. H., Lan, N., & Hellemans, K. G. C. (2008) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2008.01669.x · Cited by 329 · see citing works
Neurocognitive profile in children with fetal alcohol spectrum disorders
Kodituwakku, P. W. (2009) · Developmental Disabilities Research Reviews · doi:10.1002/ddrr.73 · Cited by 261 · see citing works
Self-citation
Developmental malformation of the corpus callosum: a review of typical callosal development and examples of developmental disorders with callosal involvement
Paul, L. K. (2010) · Journal of Neurodevelopmental Disorders · doi:10.1007/s11689-010-9059-y · Cited by 259 · see citing works
Neuroimaging and fetal alcohol spectrum disorders
Norman, A. L., Crocker, N., Mattson, S. N., & Riley, E. P. (2009) · Developmental Disabilities Research Reviews · doi:10.1002/ddrr.72 · Cited by 253 · see citing works
Magnetic Resonance Imaging Outcomes From a Comprehensive Magnetic Resonance Study of Children With Fetal Alcohol Spectrum Disorders
Astley, S. J., Aylward, E., Olson, H. C., Kerns, K. A., Brooks, A., Coggins, T. E., Davies, J. K., Dorn, S., Gendler, B., Jirikowic, T., et al. (2009) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2009.01004.x · Cited by 243 · see citing works
Executive function deficits in children with fetal alcohol spectrum disorders (FASD) measured using the Cambridge Neuropsychological Tests Automated Battery (CANTAB)
Green, C. R., Mihic, A., Nikkel, S. M., Stade, B. C., Rasmussen, C., Munoz, D. P., & Reynolds, J. N. (2009) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2008.01990.x · Cited by 236 · see citing works
Stress during development: Impact on neuroplasticity and relevance to psychopathology
Fumagalli, F., Molteni, R., Racagni, G., & Riva, M. A. (2007) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2007.01.002 · Cited by 218 · see citing works
Effects of prenatal alcohol exposure on hippocampal volume, verbal learning, and verbal and spatial recall in late childhood
Willoughby, K. A., Sheard, E. D., NASH, K., & ROVET, J. F. (2008) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617708081368 · Cited by 206 · see citing works
Psychiatric conditions associated with prenatal alcohol exposure
O’Connor, M. J., & Paley, B. (2009) · Developmental Disabilities Research Reviews · doi:10.1002/ddrr.74 · Cited by 197 · see citing works
High-throughput classification of clinical populations from natural viewing eye movements
Tseng, P.-H., Cameron, I. G. M., Pari, G., Reynolds, J. N., Munoz, D. P., & Itti, L. (2012) · Journal of Neurology · doi:10.1007/s00415-012-6631-2 · Cited by 168 · see citing works
Intellectual disability: definition, etiological factors, classification, diagnosis, treatment and prognosis
Katz, G., & Lazcano-Ponce, E. C. (2008) · Salud Pública de México · doi:10.1590/s0036-36342008000800005 · Cited by 169 · see citing works
Social Cognitive and Emotion Processing Abilities of Children With Fetal Alcohol Spectrum Disorders: A Comparison With Attention Deficit Hyperactivity Disorder
Greenbaum, R., Stevens, S. A., Nash, K., Koren, G., & ROVET, J. F. (2009) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2009.01003.x · Cited by 159 · see citing works
The impact of prenatal alcohol exposure on social, cognitive and affective behavioral domains: Insights from rodent models
Marquardt, K., & Brigman, J. L. (2016) · Alcohol · doi:10.1016/j.alcohol.2015.12.002 · Cited by 149 · see citing works
Choline supplementation in children with fetal alcohol spectrum disorders: a randomized, double-blind, placebo-controlled trial
Wozniak, J. R., Fuglestad, A. J., Eckerle, J. K., Fink, B. A., Hoecker, H. L., Boys, C. J., Radke, J. P., Kroupina, M., Miller, N. C., Brearley, A. M., et al. (2015) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.114.099168 · Cited by 131 · see citing works
Microstructural Corpus Callosum Anomalies in Children With Prenatal Alcohol Exposure: An Extension of Previous Diffusion Tensor Imaging Findings
Wozniak, J. R., Muetzel, R. L., Mueller, B. A., Petrenko, C. L. M., Freerks, M. A., Ward, E. E., Nelson, M. L., Chang, P., & Lim, K. O. (2009) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2009.01021.x · Cited by 130 · see citing works
Intervention for individuals with fetal alcohol spectrum disorders: Treatment approaches and case management
Paley, B., & O’Connor, M. J. (2009) · Developmental Disabilities Research Reviews · doi:10.1002/ddrr.67 · Cited by 121 · see citing works
Prenatal exposure to moderate levels of ethanol alters social behavior in adult rats: Relationship to structural plasticity and immediate early gene expression in frontal cortex
Hamilton, D. A., Akers, K. G., Rice, J. P., Johnson, T. E., Candelaria‐Cook, F. T., Maes, L. I., Rosenberg, M. J., Valenzuela, C. F., & Savage, D. D. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2009.10.012 · Cited by 118 · see citing works
Abnormal Cortical Thickness Alterations in Fetal Alcohol Spectrum Disorders and Their Relationships with Facial Dysmorphology
Yang, Y., Roussotte, F. F., Kan, E., Sulik, K. K., Mattson, S. N., Riley, E. P., Jones, K. L., Adnams, C. M., May, P. A., O'Connor, M. J., et al. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhr193 · Cited by 117 · see citing works
Improving executive functioning in children with fetal alcohol spectrum disorders
Nash, K., Stevens, S., Greenbaum, R., Weiner, J., Koren, G., & Rovet, J. (2015) · Child Neuropsychology · doi:10.1080/09297049.2014.889110 · Cited by 113 · see citing works
Developmental cortical thinning in fetal alcohol spectrum disorders
Zhou, D., Lebel, C. A., Lepage, C., Rasmussen, C., Evans, A. C., Wyper, K., Pei, J. R., Andrew, G., Massey, A., Massey, D., et al. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2011.06.026 · Cited by 112 · see citing works
Effects of prenatal alcohol exposure (PAE): insights into FASD using mouse models of PAE
Petrelli, B., Weinberg, J., & Hicks, G. G. (2018) · Biochemistry and Cell Biology · doi:10.1139/bcb-2017-0280 · Cited by 111 · see citing works
The effects of low to moderate alcohol consumption and binge drinking in early pregnancy on executive function in 5‐year‐old children
Skogerbø, Å., Kesmodel, U., Wimberley, T., Støvring, H., Bertrand, J., Landrø, N., & Mortensen, E. L. (2012) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.2012.03397.x · Cited by 112 · see citing works
Review of Rodent Models of Attention Deficit Hyperactivity Disorder
Regan, S. L., Williams, M. T., & Vorhees, C. (2021) · Neuroscience and Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.11.041 · Cited by 96 · see citing works
Prenatal Alcohol Exposure, FASD, and Child Behavior: A Meta-analysis
Tsang, T. W., Lucas, B. R., Olson, H. C., Pinto, R. Z., & Elliott, E. J. (2016) · PEDIATRICS · doi:10.1542/peds.2015-2542 · Cited by 106 · see citing works
Validation of the fetal alcohol spectrum disorder (FASD) 4-Digit Diagnostic Code.
Astley, S. J. (2013) · PubMed · Cited by 105 · see citing works
Reproductive Toxicology and Teratology of Abused Toluene
Hannigan, J. H., & Bowen, S. E. (2010) · Systems Biology in Reproductive Medicine · doi:10.3109/19396360903377195 · Cited by 103 · see citing works
Chronic exposure to ethanol of male mice before mating produces attention deficit hyperactivity disorder‐like phenotype along with epigenetic dysregulation of dopamine transporter expression in mouse offspring
Kim, P., Choi, C. S., Park, J. H., Joo, S. H., Kim, S. Y., Ko, H. M., Kim, K. C., Jeon, S. J., Park, S. H., Han, S., et al. (2014) · Journal of Neuroscience Research · doi:10.1002/jnr.23275 · Cited by 100 · see citing works
A 14-year retrospective maternal report of alcohol consumption in pregnancy predicts pregnancy and teen outcomes
Hannigan, J. H., Chiodo, L. M., Sokol, R. J., Janisse, J. J., Ager, J. W., Greenwald, M. K., & Delaney‐Black, V. (2009) · Alcohol · doi:10.1016/j.alcohol.2009.03.003 · Cited by 99 · see citing works
Animal models of fetal alcohol spectrum disorders: Impact of the social environment
Kelly, S. J., Goodlett, C. R., & Hannigan, J. H. (2009) · Developmental Disabilities Research Reviews · doi:10.1002/ddrr.69 · Cited by 97 · see citing works
Sleep Problems in Children with Fetal Alcohol Spectrum Disorders
Chen, M. L., Olson, H. C., Picciano, J. F., Starr, J. R., & Owens, J. A. (2012) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.2038 · Cited by 97 · see citing works
Neuropsychological Study of FASD in a Sample of American Indian Children: Processing Simple Versus Complex Information
Aragón, A. S., Kalberg, W. O., Buckley, D. G., Barela‐Scott, L. M., Tabachnick, B. G., & May, P. A. (2008) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2008.00802.x · Cited by 94 · see citing works
Neuropyschological and behavioral outcomes from a comprehensive magnetic resonance study of children with fetal alcohol spectrum disorders.
Astley, S. J., Olson, H. C., Kerns, K. A., Brooks, A., Aylward, E., Coggins, T. E., Davies, J. K., Dorn, S., Gendler, B., Jirikowic, T., et al. (2009) · PubMed · Cited by 92 · see citing works
Choline supplementation mitigates trace, but not delay, eyeblink conditioning deficits in rats exposed to alcohol during development
Thomas, J. D., & Tran, T. D. (2011) · Hippocampus · doi:10.1002/hipo.20925 · Cited by 91 · see citing works
Mechanisms of Ethanol-Induced Death of Cerebellar Granule Cells
Luo, J. (2010) · The Cerebellum · doi:10.1007/s12311-010-0219-0 · Cited by 86 · see citing works
Executive Functioning in Children and Adolescents Prenatally Exposed to Alcohol: A Meta-Analytic Review
Khoury, J. E., Milligan, K., & Girard, T. A. (2015) · Neuropsychology Review · doi:10.1007/s11065-015-9289-6 · Cited by 85 · see citing works
Prevalence and profile of Neurodevelopment and Fetal Alcohol Spectrum Disorder (FASD) amongst Australian Aboriginal children living in remote communities
Fitzpatrick, J. P., Latimer, J., Olson, H. C., Carter, M., Oscar, J., Lucas, B. R., Doney, R., Salter, C., Try, J., Hawkes, G., et al. (2017) · Research in Developmental Disabilities · doi:10.1016/j.ridd.2017.04.001 · Cited by 84 · see citing works
Maternal voluntary drinking in C57BL/6J mice: Advancing a model for fetal alcohol spectrum disorders
Kleiber, M. L., Wright, E., & Singh, S. M. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.05.005 · Cited by 83 · see citing works
Neurodevelopmental Functioning in Children With FAS, pFAS, and ARND
Chasnoff, I. J., Wells, A. M., Telford, E., Schmidt, C., & Messer, G. (2010) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/dbp.0b013e3181d5a4e2 · Cited by 82 · see citing works
Prenatal alcohol exposure: An assessment strategy for the legal context
Brown, N. N., Burd, L., Grant, T. M., Edwards, W., Adler, R. S., & Streissguth, A. P. (2015) · International Journal of Law and Psychiatry · doi:10.1016/j.ijlp.2015.08.019 · Cited by 80 · see citing works
Evaluating the psycholegal abilities of young offenders with fetal alcohol spectrum disorder.
McLachlan, K., Roesch, R. G., Viljoen, J. L., & Douglas, K. S. (2013) · Law and Human Behavior · doi:10.1037/lhb0000037 · Cited by 79 · see citing works
Effects of prenatal tobacco, alcohol and marijuana exposure on processing speed, visual–motor coordination, and interhemispheric transfer
Willford, J. A., Chandler, L. S., Goldschmidt, L., & Day, N. L. (2010) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2010.06.004 · Cited by 78 · see citing works
Autism characteristics in children with fetal alcohol spectrum disorders
Stevens, S. A., Nash, K., Koren, G., & ROVET, J. F. (2012) · Child Neuropsychology · doi:10.1080/09297049.2012.727791 · Cited by 77 · see citing works
Ethanol Affects Differentiation‐Related Pathways and Suppresses Wnt Signaling Protein Expression in Human Neural Stem Cells
Vangipuram, S. D., & Lyman, W. D. (2011) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2011.01682.x · Cited by 75 · see citing works
Adaptive behaviour in children and adolescents with foetal alcohol spectrum disorders: a comparison with specific learning disability and typical development
Fagerlund, Å., Autti‐Rämö, I., Kalland, M., Santtila, P., Hoyme, H. E., Mattson, S. N., & Korkman, M. (2012) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-012-0256-y · Cited by 75 · see citing works
Magnetic resonance spectroscopy outcomes from a comprehensive magnetic resonance study of children with fetal alcohol spectrum disorders
Astley, S. J., Richards, T. L., Aylward, E., Olson, H. C., Kerns, K. A., Brooks, A., Coggins, T. E., Davies, J. K., Dorn, S., Gendler, B., et al. (2009) · Magnetic Resonance Imaging · doi:10.1016/j.mri.2009.01.003 · Cited by 74 · see citing works
Effects of moderate prenatal ethanol exposure and age on social behavior, spatial response perseveration errors and motor behavior
Hamilton, D. A., Barto, D., Rodriguez, C. I., Magcalas, C. M., Fink, B. C., Rice, J. P., Bird, C. W., Davies, S., & Savage, D. D. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.04.029 · Cited by 73 · see citing works
Embryonic alcohol exposure impairs associative learning performance in adult zebrafish
Fernandes, Y., Tran, S., Abraham, E., & Gerlai, R. T. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.02.035 · Cited by 73 · see citing works
Embryonic Alcohol Exposure Impairs the Dopaminergic System and Social Behavioral Responses in Adult Zebrafish
Fernandes, Y., Rampersad, M., & Gerlai, R. T. (2015) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyu089 · Cited by 73 · see citing works
Prenatal Ethanol Exposure Disrupts Intraneocortical Circuitry, Cortical Gene Expression, and Behavior in a Mouse Model of FASD
Shawa, H. E., Abbott, C. W., & Huffman, K. J. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.3721-13.2013 · Cited by 72 · see citing works
Fishing for Fetal Alcohol Spectrum Disorders: Zebrafish as a Model for Ethanol Teratogenesis
Lovely, C. B., Fernandes, Y., & Eberhart, J. K. (2016) · Zebrafish · doi:10.1089/zeb.2016.1270 · Cited by 71 · see citing works
A neurodevelopmental framework for the development of interventions for children with fetal alcohol spectrum disorders
Kodituwakku, P. W. (2009) · Alcohol · doi:10.1016/j.alcohol.2009.10.009 · Cited by 70 · see citing works
Self-citation
Is prenatal alcohol exposure related to inattention and hyperactivity symptoms in children? Disentangling the effects of social adversity
Rodriguez, A., Olsen, J., Kotimaa, A., Kaakinen, M., Moilanen, I., Henriksen, T. B., Línnet, K., Miettunen, J., Obel, C., Taanila, A. M., et al. (2009) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2009.02071.x · Cited by 69 · see citing works
The impact of an ADHD co-morbidity on the diagnosis of FASD.
Rasmussen, C., Benz, J., Pei, J. R., Andrew, G., Schuller, G., Abele-Webster, L., Alton, C., & Lord, L. (2010) · PubMed · Cited by 67 · see citing works
Fine Motor Skills in Children With Prenatal Alcohol Exposure or Fetal Alcohol Spectrum Disorder
Doney, R., Lucas, B. R., Jones, T., Howat, P. A., Sauer, K., & Elliott, E. J. (2014) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/dbp.0000000000000107 · Cited by 66 · see citing works
Functional magnetic resonance imaging outcomes from a comprehensive magnetic resonance study of children with fetal alcohol spectrum disorders
Astley, S. J., Aylward, E., Olson, H. C., Kerns, K. A., Brooks, A., Coggins, T. E., Davies, J. K., Dorn, S., Gendler, B., Jirikowic, T., et al. (2009) · Journal of Neurodevelopmental Disorders · doi:10.1007/s11689-009-9004-0 · Cited by 65 · see citing works
From Research to Practice: An Integrative Framework for the Development of Interventions for Children with Fetal Alcohol Spectrum Disorders
Kodituwakku, P. W., & Kodituwakku, E. L. (2011) · Neuropsychology Review · doi:10.1007/s11065-011-9170-1 · Cited by 65 · see citing works
Self-citation
Sexual dimorphism of volume reduction but not cognitive deficit in fetal alcohol spectrum disorders: A combined diffusion tensor imaging, cortical thickness and brain volume study
Treit, S., Chen, Z., Zhou, D., Baugh, L., Rasmussen, C., Andrew, G., Pei, J. R., & Beaulieu, C. (2017) · NeuroImage Clinical · doi:10.1016/j.nicl.2017.05.006 · Cited by 63 · see citing works
Caudate Volume Predicts Neurocognitive Performance in Youth with Heavy Prenatal Alcohol Exposure
Fryer, S. L., Mattson, S. N., Jernigan, T. L., Archibald, S. L., Jones, K. L., & Riley, E. P. (2012) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2012.01811.x · Cited by 62 · see citing works
Cognitive and Behavioral Profiles of Children with Fetal Alcohol Spectrum Disorders
Kodituwakku, P. W., & Kodituwakku, E. L. (2014) · Current Developmental Disorders Reports · doi:10.1007/s40474-014-0022-6 · Cited by 61 · see citing works
Self-citation
Deficits in trace fear conditioning in a rat model of fetal alcohol exposure: dose–response and timing effects
Hunt, P. S., Jacobson, S. E., & Torok, E. J. (2009) · Alcohol · doi:10.1016/j.alcohol.2009.08.004 · Cited by 60 · see citing works
Impact of a Social Skills Intervention on the Hostile Attributions of Children With Prenatal Alcohol Exposure
Keil, V., Paley, B., Frankel, F., & O’Connor, M. J. (2009) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2009.01086.x · Cited by 60 · see citing works
Caregiver needs and stress in caring for individuals with fetal alcohol spectrum disorder
Bobbitt, S. A., Baugh, L. A., Andrew, G., Cook, J. L., Green, C. R., Pei, J. R., & Rasmussen, C. (2016) · Research in Developmental Disabilities · doi:10.1016/j.ridd.2016.03.002 · Cited by 60 · see citing works
Cortical morphology in children with alcohol‐related neurodevelopmental disorder
Rajaprakash, M., Chakravarty, M. M., Lerch, J. P., & ROVET, J. F. (2013) · Brain and Behavior · doi:10.1002/brb3.191 · Cited by 59 · see citing works
Postnatal day 7 ethanol treatment causes persistent reductions in adult mouse brain volume and cortical neurons with sex specific effects on neurogenesis
Coleman, L. G., Oğuz, İ., Lee, J., Styner, M. A., & Crews, F. T. (2012) · Alcohol · doi:10.1016/j.alcohol.2012.01.003 · Cited by 59 · see citing works
Social Information Processing Skills in Children with Histories of Heavy Prenatal Alcohol Exposure
Petrenko, C. L. M., Bjorkquist, O. A., Price, J. M., Mattson, S. N., & Riley, E. P. (2009) · Research on Child and Adolescent Psychopathology · doi:10.1007/s10802-009-9313-5 · Cited by 58 · see citing works
The Relation Between Mathematics and Working Memory in Young Children With Fetal Alcohol Spectrum Disorders
Rasmussen, C., & Bisanz, J. (2010) · The Journal of Special Education · doi:10.1177/0022466909356110 · Cited by 58 · see citing works
Impairment of social behaviour persists two years after embryonic alcohol exposure in zebrafish: A model of fetal alcohol spectrum disorders
Fernandes, Y., Rampersad, M., & Gerlai, R. T. (2015) · Behavioural Brain Research · doi:10.1016/j.bbr.2015.05.060 · Cited by 58 · see citing works
Self-regulation therapy increases frontal gray matter in children with fetal alcohol spectrum disorder: evaluation by voxel-based morphometry
Soh, D. W., Skocic, J., Nash, K., Stevens, S. A., Turner, G. R., & ROVET, J. F. (2015) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2015.00108 · Cited by 56 · see citing works
Oculomotor control in children with fetal alcohol spectrum disorders assessed using a mobile eye‐tracking laboratory
Green, C. R., Mihic, A., Brien, D. C., Armstrong, I. T., Nikkel, S. M., Stade, B. C., Rasmussen, C., Munoz, D. P., & Reynolds, J. N. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.06668.x · Cited by 56 · see citing works
Cingulate gyrus morphology in children and adolescents with fetal alcohol spectrum disorders
Bjorkquist, O. A., Fryer, S. L., Reiss, A. L., Mattson, S. N., & Riley, E. P. (2010) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2009.10.004 · Cited by 55 · see citing works
Verbal and Nonverbal Memory in Adults Prenatally Exposed to Alcohol
Coles, C. D., Lynch, M. E., Kable, J. A., Johnson, K. C., & Goldstein, F. C. (2010) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2010.01162.x · Cited by 55 · see citing works
Teratology: From science to birth defects prevention
Rasmussen, S. A., Erickson, J. D., Reef, S. E., & Ross, D. S. (2008) · Birth Defects Research Part A Clinical and Molecular Teratology · doi:10.1002/bdra.20506 · Cited by 55 · see citing works
Mental Health and Affect Regulation Impairment in Fetal Alcohol Spectrum Disorder (FASD): Results from the Canadian National FASD Database
Temple, V. K., Cook, J. L., Unsworth, K., Rajani, H., & Mela, M. (2019) · Alcohol and Alcoholism · doi:10.1093/alcalc/agz049 · Cited by 55 · see citing works
Fetal alcohol exposure leads to abnormal olfactory bulb development and impaired odor discrimination in adult mice
Akers, K. G., Kushner, S. A., Leslie, A. T. F. S., Clarke, L., van der Kooy, D., Lerch, J. P., & Frankland, P. W. (2011) · Molecular Brain · doi:10.1186/1756-6606-4-29 · Cited by 54 · see citing works
The Impact of Fetal Alcohol Spectrum Disorders on Families: Evaluation of a Family Intervention Program
Leenaars, L. S., Denys, K., Henneveld, D., & Rasmussen, C. (2011) · Community Mental Health Journal · doi:10.1007/s10597-011-9425-6 · Cited by 51 · see citing works
Developmental Ethanol Exposure Leads to Dysregulation of Lipid Metabolism and Oxidative Stress in Drosophila
Logan-Garbisch, T., Bortolazzo, A., Luu, P., Ford, A. C., Do, D., Khodabakhshi, P., & French, R. L. (2014) · G3 Genes Genomes Genetics · doi:10.1534/g3.114.015040 · Cited by 51 · see citing works
Salivary cortisol levels are elevated in the afternoon and at bedtime in children with prenatal alcohol exposure
Keiver, K., Bertram, C. P., Orr, A. P., & Clarren, S. K. (2014) · Alcohol · doi:10.1016/j.alcohol.2014.11.004 · Cited by 48 · see citing works
Effects of one- and three-day binge alcohol exposure in neonatal C57BL/6 mice on spatial learning and memory in adolescence and adulthood
Wagner, J. L., Zhou, F., & Goodlett, C. R. (2014) · Alcohol · doi:10.1016/j.alcohol.2013.12.001 · Cited by 48 · see citing works
The Clinical Utility and Specificity of Parent Report of Executive Function among Children with Prenatal Alcohol Exposure
Nguyen, T. T., Glass, L., Coles, C. D., Kable, J. A., May, P. A., Kalberg, W. O., Sowell, E. R., Jones, K. L., Riley, E. P., Mattson, S. N., et al. (2014) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617714000599 · Cited by 48 · see citing works
Intrahippocampal administration of an NMDA-receptor antagonist impairs spatial discrimination reversal learning in weanling rats
Watson, D. J., & Stanton, M. E. (2009) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2009.02.005 · Cited by 49 · see citing works
Exploring the Complexity of Intellectual Disability in Fetal Alcohol Spectrum Disorders
Chokroborty-Hoque, A., Alberry, B., & Singh, S. M. (2014) · Frontiers in Pediatrics · doi:10.3389/fped.2014.00090 · Cited by 46 · see citing works
Up-regulation of Siah1 by ethanol triggers apoptosis in neural crest cells through p38 MAPK-mediated activation of p53 signaling pathway
Yuan, F., Chen, X., Liu, J., Feng, W., Wu, X., & Chen, S. (2016) · Archives of Toxicology · doi:10.1007/s00204-016-1746-3 · Cited by 45 · see citing works
Are Brain and Cognitive Reserve Shaped by Early Life Circumstances?
de Rooij, S. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.825811 · Cited by 38 · see citing works
A Metric of Maternal Prenatal Risk Drinking Predicts Neurobehavioral Outcomes in Preschool Children
Chiodo, L. M., Janisse, J. J., Delaney‐Black, V., Sokol, R. J., & Hannigan, J. H. (2009) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2008.00878.x · Cited by 46 · see citing works
Social Perspective Taking and Empathy in Children with Fetal Alcohol Spectrum Disorders
Stevens, S. A., Dudek, J., Nash, K., Koren, G., & ROVET, J. F. (2015) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617714001088 · Cited by 45 · see citing works
Neurobehavioral, neurologic, and neuroimaging characteristics of fetal alcohol spectrum disorders
Glass, L., Ware, A. L., & Mattson, S. N. (2014) · Handbook of clinical neurology · doi:10.1016/b978-0-444-62619-6.00025-2 · Cited by 45 · see citing works
Neuropsychological deficits associated with heavy prenatal alcohol exposure are not exacerbated by ADHD.
Glass, L., (CIFASD), C. I. O. F. A. S. D., Ware, A. L., Crocker, N., Deweese, B. N., Coles, C. D., Kable, J. A., May, P. A., Kalberg, W. O., Sowell, E. R., et al. (2013) · Neuropsychology · doi:10.1037/a0033994 · Cited by 44 · see citing works
A Functional Magnetic Resonance Imaging Study of Spatial Working Memory in Children with Prenatal Alcohol Exposure: Contribution of Familial History of Alcohol Use Disorders
Norman, A. L., O’Brien, J. W., Spadoni, A. D., Tapert, S. F., Jones, K. L., Riley, E. P., & Mattson, S. N. (2012) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2012.01880.x · Cited by 44 · see citing works
Long-term Reductions in the Population of GABAergic Interneurons in the Mouse Hippocampus following Developmental Ethanol Exposure
Bird, C. W., Taylor, D. H., Pinkowski, N. J., Chavez, G. J., & Valenzuela, C. F. (2018) · Neuroscience · doi:10.1016/j.neuroscience.2018.05.003 · Cited by 43 · see citing works
Effects of exposure to moderate levels of ethanol during prenatal brain development on dendritic length, branching, and spine density in the nucleus accumbens and dorsal striatum of adult rats
Rice, J. P., Suggs, L. E., Lusk, A. V., Parker, M. O., Candelaria‐Cook, F. T., Akers, K. G., Savage, D. D., & Hamilton, D. A. (2012) · Alcohol · doi:10.1016/j.alcohol.2011.11.008 · Cited by 43 · see citing works
Clinical improvements in adopted children with fetal alcohol spectrum disorders through neurodevelopmentally informed clinical intervention: A pilot study
Zarnegar, Z., Hambrick, E. P., Perry, B. D., Azen, S. P., & Peterson, C. (2016) · Clinical Child Psychology and Psychiatry · doi:10.1177/1359104516636438 · Cited by 43 · see citing works
Moderate Maternal Alcohol Exposure on Gestational Day 12 Impacts Anxiety-Like Behavior in Offspring
Rouzer, S. K., Cole, J. M., Johnson, J. M., Varlinskaya, E. I., & Diaz, M. R. (2017) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2017.00183 · Cited by 43 · see citing works
Cognitive aspects of fetal alcohol spectrum disorder
Davis, K. M., Gagnier, K. R., Moore, T. E., & Todorow, M. (2012) · Wiley Interdisciplinary Reviews Cognitive Science · doi:10.1002/wcs.1202 · Cited by 43 · see citing works
Diving into the world of alcohol teratogenesis: a review of zebrafish models of fetal alcohol spectrum disorder
Fernandes, Y., Buckley, D. M., & Eberhart, J. K. (2017) · Biochemistry and Cell Biology · doi:10.1139/bcb-2017-0122 · Cited by 42 · see citing works
Intellectual disability across the lifespan
Klein-Tasman, B., & Janke, K. M. (2010) · Cambridge University Press eBooks · doi:10.1017/cbo9780511674815.018 · Cited by 41 · see citing works
Prenatal Alcohol Exposure, Adaptive Function, and Entry into Adult Roles in a Prospective Study of Young Adults
Lynch, M. E., Kable, J., & Coles, C. (2015) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2015.07.008 · Cited by 38 · see citing works
The effects of low to moderate alcohol consumption and binge drinking in early pregnancy on behaviour in 5‐year‐old children: a prospective cohort study on 1628 children
Skogerbø, Å., Kesmodel, U., Denny, C., Kjaersgaard, M., Wimberley, T., Landrø, N., & Mortensen, E. L. (2013) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.12208 · Cited by 41 · see citing works

A Review of the Neurobehavioral Deficits in Children with Fetal Alcohol Syndrome or Prenatal Exposure to Alcohol
Mattson, S. N., & Riley, E. P. (1998) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1998.tb03651.x · Cited by 608 · see citing works
Cognitive and Behavioral Effects of Prenatal Alcohol Exposure
Kodituwakku, P. W., Segall, J. M., & Beatty, G. K. (2011) · Future Neurology · doi:10.2217/fnl.11.4 · Cited by 26 · see citing works
Self-citation
Teratogenic effects of alcohol on brain and behaviour
Mattson, S. N., Amy, P. D., Schoenfeld, M., Riley, E. P., & Ph., D. (2001)
Teratogenic effects of alcohol on brain and behavior.
Mattson, S. N., Schoenfeld, A. M., & Riley, E. P. (2001) · PubMed · Cited by 310 · see citing works
Higher functioning children with prenatal alcohol exposure: Is there a specific neurocognitive profile?
Quattlebaum, J., & O’Connor, M. J. (2012) · Child Neuropsychology · doi:10.1080/09297049.2012.713466 · Cited by 48 · see citing works

Authors: Kodituwakku, P. W.
Affiliations: University of New Mexico (US)
Corresponding author: Kodituwakku, P.W.
ORCID: Kodituwakku, P.W.
Venue: Neuroscience & Biobehavioral Reviews
Publisher: Elsevier BV
Published: 2007-01
Volume: 31
Issue: 2
Pages: 192-201
ISSN: 0149-7634 (ISSN-L)
DOI: 10.1016/j.neubiorev.2006.06.020
OpenAlex: W2089055897
Cited by: 359
References: 92
Citations by year: 2026: 4 · 2025: 4 · 2024: 5 · 2023: 11 · 2022: 7 · 2021: 13 · 2020: 15 · 2019: 15 · 2018: 17 · 2017: 18 · 2016: 28 · 2015: 28 · 2014: 29 · 2013: 26 · 2012: 27
FWCI: 2.59
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Neuroscience & Biobehavioral Reviews (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Substance Exposure Effects
Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Fetal and Pediatric Neurological Disorders
Keywords: fetal alcohol spectrum disorders, prenatal alcohol exposure, behavioral phenotypes, intellectual functioning, inattention, attention deficits, information processing deficits, adaptive behavior, socialization deficits, language deficits, visual perception, memory impairment, developmental processes
MeSH terms: Animals, Behavioral Symptoms, Child, Cognition, Female, Humans, Language, Learning, Male, Models, Biological, Phenotype, Pregnancy, Problem Solving, Visual Perception, Fetal Alcohol Spectrum Disorders

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Defining the behavioral phenotype in children with fetal alcohol spectrum disorders: A review

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Cites

Cited by

Related

Record

About these checks