ABCA7 expression is associated with Alzheimer's disease polymorphism and disease status

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Chomczynski, P., & Sacchi, N. (1987) · Analytical Biochemistry · doi:10.1006/abio.1987.9999 · Cited by 65,240 · see citing works

Global prevalence of dementia: a Delphi consensus study

Ferri, C. P., Prince, M. J., Brayne, C., Brodaty, H., Fratiglioni, L., Ganguli, M., Hall, K. S., Hasegawa, K., Hendrie, H. C., Huang, Y., et al. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67889-0 · Cited by 5,336 · see citing works

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

Terry, R. D., Masliah, E., Salmon, D. P., Butters, N., DeTeresa, R., Hill, R., Hansen, L. A., & Katzman, R. (1991) · Annals of Neurology · doi:10.1002/ana.410300410 · Cited by 4,397 · see citing works

<i>TREM2</i> Variants in Alzheimer's Disease

Guerreiro, R., Wojtas, A., Bras, J., Carrasquillo, M., Rogaeva, E., Majounie, E., Cruchaga, C., Sassi, C., Kauwe, J. S. K., Younkin, S., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1211851 · Cited by 3,020 · see citing works

Variant of <i>TREM2</i> Associated with the Risk of Alzheimer's Disease

Jonsson, T., Stefansson, H., Steinberg, S., Jonsdottir, I., Jonsson, P. V., Snaedal, J., Bjornsson, S., Huttenlocher, J., Levey, A. I., Lah, J. J., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1211103 · Cited by 2,558 · see citing works

Alzheimer Disease in the US Population: Prevalence Estimates Using the 2000 Census

Hebert, L. E., Scherr, P. A., Bienias, J. L., Bennett, D. A., & Evans, D. A. (2003) · Archives of Neurology · doi:10.1001/archneur.60.8.1119 · Cited by 2,168 · see citing works

The single-step method of RNA isolation by acid guanidinium thiocyanate–phenol–chloroform extraction: twenty-something years on

Chomczyński, P., & Sacchi, N. (2006) · Nature Protocols · doi:10.1038/nprot.2006.83 · Cited by 2,084 · see citing works

Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset.

Brookmeyer, R., Gray, S. G., & Kawas, C. H. (1998) · American Journal of Public Health · doi:10.2105/ajph.88.9.1337 · Cited by 1,774 · see citing works

Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta

Griciuc, A., Serrano-Pozo, A., Parrado, A. R., Lesinski, A. N., Asselin, C. N., Mullin, K., Hooli, B., Choi, S. H., Hyman, B. T., & Tanzi, R. E. (2013) · Neuron · doi:10.1016/j.neuron.2013.04.014 · Cited by 1,004 · see citing works

Neuropathology of Alzheimer's Disease

Perl, D. P. (2010) · Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine · doi:10.1002/msj.20157 · Cited by 825 · see citing works

The question of familial meningiomas and schwannomas:

King, A. A., & Gutmann, D. H. (2000) · Neurology · doi:10.1212/wnl.54.1.4 · Cited by 814 · see citing works

Neuropathology and Cognitive Impairment in Alzheimer Disease: A Complex but Coherent Relationship

Nelson, P. T., Braak, H., & Markesbery, W. R. (2009) · Journal of Neuropathology &amp; Experimental Neurology · doi:10.1097/nen.0b013e3181919a48 · Cited by 643 · see citing works

Genetics and Beyond – The Transcriptome of Human Monocytes and Disease Susceptibility

Zeller, T., Wild, P. S., Szymczak, S., Rotival, M., Schillert, A., Castagné, R., Maouche, S., Germain, M., Lackner, K. J., Rossmann, H., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010693 · Cited by 584 · see citing works

CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology

Initiative, T. A. D. N., Bradshaw, E. M., Chibnik, L. B., Keenan, B. T., Ottoboni, L., Raj, T., Tang, A., Rosenkrantz, L. L., Imboywa, S., Lee, M., et al. (2013) · Nature Neuroscience · doi:10.1038/nn.3435 · Cited by 570 · see citing works

High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1

McNeish, J. D., Aiello, R. J., Guyot, D. J., Turi, T., Gabel, C. A., Aldinger, C. E., Hoppe, K. L., Roach, M. L., Royer, L. J., de Wet, J., et al. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.8.4245 · Cited by 539 · see citing works

Estimated Prevalence of Alzheimer's Disease in the United States

Evans, D. A. (1990) · Milbank Quarterly · doi:10.2307/3350099 · Cited by 356 · see citing works

Lack of ABCA1 Considerably Decreases Brain ApoE Level and Increases Amyloid Deposition in APP23 Mice

Koldamova, R., Staufenbiel, M., & Lefterov, I. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m504513200 · Cited by 350 · see citing works

Expression of Novel Alzheimer’s Disease Risk Genes in Control and Alzheimer’s Disease Brains

Karch, C. M., Jeng, A. T., Nowotny, P., Cady, J., Cruchaga, C., & Goate, A. M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0050976 · Cited by 328 · see citing works

CD33 Alzheimer’s risk-altering polymorphism, CD33 expression, and exon 2 splicing

Malik, M., Simpson, J. F., Parikh, I., Wilfred, B. R., Fardo, D. W., Nelson, P. T., & Estus, S. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.1224-13.2013 · Cited by 262 · see citing works

The genetics and neuropathology of Alzheimer’s disease

Schellenberg, G. D., & Montine, T. J. (2012) · Acta Neuropathologica · doi:10.1007/s00401-012-0996-2 · Cited by 242 · see citing works

Role of ATP‐binding cassette transporters in brain lipid transport and neurological disease

Kim, W. S., Weickert, C. S., & Garner, B. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.05099.x · Cited by 237 · see citing works

Evidence for impaired amyloid β clearance in Alzheimer's disease

Wildsmith, K. R., Holley, M., Savage, J. C., Skerrett, R., & Landreth, G. E. (2013) · Alzheimer s Research & Therapy · doi:10.1186/alzrt187 · Cited by 234 · see citing works

ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophages

Jehle, A. W., Gardai, S. J., Li, S., Linsel‐Nitschke, P., Morimoto, K., Janssen, W. J., Vandivier, R. W., Wang, N., Greenberg, S., Dale, B. M., et al. (2006) · The Journal of Cell Biology · doi:10.1083/jcb.200601030 · Cited by 213 · see citing works

Deletion ofAbca7Increases Cerebral Amyloid-β Accumulation in the J20 Mouse Model of Alzheimer's Disease

Kim, W. S., Li, H., Ruberu, K. R., Chan, S. L., Elliott, D. A., Low, J. K., Cheng, D., Karl, T., & Garner, B. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.4165-12.2013 · Cited by 209 · see citing works

ATP-binding Cassette Transporter A7 (ABCA7) Binds Apolipoprotein A-I and Mediates Cellular Phospholipid but Not Cholesterol Efflux

Wang, N., Lan, D., Gerbod-Giannone, M. C., Linsel‐Nitschke, P., Jehle, A. W., Chen, W., Martinez, L. O., & Tall, A. R. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m307831200 · Cited by 202 · see citing works

Human ABCA7 Supports Apolipoprotein-mediated Release of Cellular Cholesterol and Phospholipid to Generate High Density Lipoprotein

Abe-Dohmae, S., Ikeda, Y., Matsuo, M., Hayashi, M., Okuhira, K., Ueda, K., & Yokoyama, S. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m309888200 · Cited by 190 · see citing works

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

Allen, M., Zou, F., Chai, H. S., Younkin, C. S., Crook, J. E., Pankratz, V. S., Carrasquillo, M. M., Rowley, C. N., Nair, A., Middha, S., et al. (2012) · Neurology · doi:10.1212/wnl.0b013e3182605801 · Cited by 164 · see citing works

β-Amyloid Induces Local Neurite Degeneration in Cultured Hippocampal Neurons: Evidence for Neuritic Apoptosis

Ivins, K. J., Bui, E. T. N., & Cotman, C. W. (1998) · Neurobiology of Disease · doi:10.1006/nbdi.1998.0228 · Cited by 164 · see citing works

Quantitation of ATP-binding cassette subfamily-A transporter gene expression in primary human brain cells

Kim, W., Guillemin, G., Glaros, E., Lim, C. K., & Garner, B. (2006) · NeuroReport · doi:10.1097/01.wnr.0000221833.41340.cd · Cited by 158 · see citing works

Genetic Susceptibility for Alzheimer Disease Neuritic Plaque Pathology

Shulman, J. M., Chen, K., Keenan, B. T., Chibnik, L. B., Fleisher, A., Thiyyagura, P., Roontiva, A., Aubin, C., Patsopoulos, N. A., Corneveaux, J. J., et al. (2013) · JAMA Neurology · doi:10.1001/jamaneurol.2013.2815 · Cited by 156 · see citing works

Abca7 Null Mice Retain Normal Macrophage Phosphatidylcholine and Cholesterol Efflux Activity despite Alterations in Adipose Mass and Serum Cholesterol Levels

Kim, W. S., Fitzgerald, M. L., Kang, K., Okuhira, K., Bell, S. A., Manning, J. J., Koehn, S. L., Lu, N., Moore, K. J., & Freeman, M. W. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m412602200 · Cited by 137 · see citing works

ATP‐binding cassette transporter A7 regulates processing of amyloid precursor protein in vitro

Chan, S. L., Kim, W. S., Kwok, J. B., Hill, A. F., Cappai, R., Rye, K., & Garner, B. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05433.x · Cited by 133 · see citing works

The role of ABCB1 and ABCA1 in beta-amyloid clearance at the neurovascular unit in Alzheimer's disease

ElAli, A., & Rivest, S. (2013) · Frontiers in Physiology · doi:10.3389/fphys.2013.00045 · Cited by 109 · see citing works

ABCA1 influences neuroinflammation and neuronal death

Karasinska, J. M., de Haan, W., Franciosi, S., Ruddle, P., Fan, J., Kruit, J. K., Stukas, S., Lütjohann, D., Gutmann, D. H., Wellington, C. L., et al. (2013) · Neurobiology of Disease · doi:10.1016/j.nbd.2013.01.018 · Cited by 104 · see citing works

The role of ATP-binding cassette transporter A1 in Alzheimer's disease and neurodegeneration

Koldamova, R., Fitz, N. F., & Lefterov, I. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2010.02.010 · Cited by 102 · see citing works

Pathological Substrates of Cognitive Decline in Alzheimer&amp;rsquo;s Disease

Giannakopoulos, P., K&ouml;vari, E., Gold, G., von Gunten, A., Hof, P. R., & Bouras, C. (2009) · Frontiers of Neurology and Neuroscience · doi:10.1159/000197881 · Cited by 101 · see citing works

A common polymorphism decreases low-density lipoprotein receptor exon 12 splicing efficiency and associates with increased cholesterol

Zhu, H., Tucker, H. M., Grear, K. E., et al. (2007) · Human Molecular Genetics · doi:10.1093/hmg/ddm124 · Cited by 99 · see citing works

Genetics of Clusterin Isoform Expression and Alzheimer's Disease Risk

Ling, I., Bhongsatiern, J., Simpson, J. F., Fardo, D. W., & Estus, S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0033923 · Cited by 75 · see citing works

Roles of ATP-Binding Cassette Transporter A7 in Cholesterol Homeostasis and Host Defense System

Tanaka, N., Abe-Dohmae, S., Iwamoto, N., & Yokoyama, S. (2011) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.6726 · Cited by 73 · see citing works

Alzheimer's-type neuropathology in the precuneus is not increased relative to other areas of neocortex across a range of cognitive impairment

Nelson, P. T., Abner, E. L., Scheff, S. W., Schmitt, F. A., Kryscio, R. J., Jicha, G. A., Smith, C. D., Patel, E., & Markesbery, W. R. (2009) · Neuroscience Letters · doi:10.1016/j.neulet.2008.11.006 · Cited by 70 · see citing works

Helical apolipoproteins of high-density lipoprotein enhance phagocytosis by stabilizing ATP-binding cassette transporter A7

Tanaka, N., Abe-Dohmae, S., Iwamoto, N., Fitzgerald, M. L., & Yokoyama, S. (2010) · Journal of Lipid Research · doi:10.1194/jlr.m006049 · Cited by 63 · see citing works

Sex-dependent association of a common low-density lipoprotein receptor polymorphism with RNA splicing efficiency in the brain and Alzheimer’s disease

Zou, F., Gopalraj, R. K., Lok, J., Zhu, H., Ling, I.-F., Simpson, J. F., Tucker, H. M., Kelly, J. F., Younkin, S. G., Dickson, D. W., et al. (2007) · Human Molecular Genetics · doi:10.1093/hmg/ddm365 · Cited by 58 · see citing works

HMG-CoA reductase inhibitors enhance phagocytosis by upregulating ATP-binding cassette transporter A7

Tanaka, N., Abe-Dohmae, S., Iwamoto, N., Fitzgerald, M. L., & Yokoyama, S. (2011) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2011.06.031 · Cited by 50 · see citing works

Thinking Outside the Box: Alzheimer-Type Neuropathology That Does Not Map Directly Onto Current Consensus Recommendations

Nelson, P. T., Kukull, W. A., & Frosch, M. P. (2010) · Journal of Neuropathology &amp; Experimental Neurology · doi:10.1097/nen.0b013e3181d8db07 · Cited by 37 · see citing works

Novel mutations of ABCA1 transporter in patients with Tangier disease and familial HDL deficiency

Fasano, T., Zanoni, P., Rabacchi, C., Pisciotta, L., Favari, E., Adorni, M. P., Deegan, P. B., Park, A. J., Hlaing, T., Feher, M. D., et al. (2012) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2012.08.005 · Cited by 36 · see citing works

Role of SFRS13A in low-density lipoprotein receptor splicing

Ling, I., & Estus, S. (2010) · Human Mutation · doi:10.1002/humu.21244 · Cited by 23 · see citing works

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Alzheimer Disease Genetics Consortium (ADGC), Kunkle, B. W., The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), Genetic and Environmental Risk in AD/Defining Genetic, P. A. E. R. F. A. D. C. (., Grenier-Boley, B., Sims, R., Bis, J. C., Damotte, V., Naj, A. C., et al. (2019) · Nature Genetics · doi:10.1038/s41588-019-0358-2 · Cited by 2,946 · see citing works

Alzheimer’s Disease Risk Genes and Mechanisms of Disease Pathogenesis

Karch, C. M., & Goate, A. M. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2014.05.006 · Cited by 1,357 · see citing works

The genetic landscape of Alzheimer disease: clinical implications and perspectives

Van Cauwenberghe, C., Van Broeckhoven, C., & Sleegers, K. (2016) · Genetics in Medicine · doi:10.1038/gim.2015.117 · Cited by 863 · see citing works

Late onset Alzheimer’s disease genetics implicates microglial pathways in disease risk

Efthymiou, A. G., & Goate, A. M. (2017) · Molecular Neurodegeneration · doi:10.1186/s13024-017-0184-x · Cited by 562 · see citing works

Microglial genes regulating neuroinflammation in the progression of Alzheimer's disease

Villegas-Llerena, C., Phillips, A., Garcia-Reitboeck, P., Hardy, J., & Pocock, J. M. (2016) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2015.10.004 · Cited by 270 · see citing works

Genetics ignite focus on microglial inflammation in Alzheimer’s disease

Malik, M., Parikh, I., Vasquez, J. B., Smith, C., Tai, L., Bu, G., LaDu, M. J., Fardo, D. W., Rebeck, G. W., & Estus, S. (2015) · Molecular Neurodegeneration · doi:10.1186/s13024-015-0048-1 · Cited by 161 · see citing works

Mutations in ABCA7 in a Belgian cohort of Alzheimer's disease patients: a targeted resequencing study

Cuyvers, E., De Roeck, A., Van den Bossche, T., Van Cauwenberghe, C., Bettens, K., Vermeulen, S., Mattheijssens, M., Peeters, K., Engelborghs, S., Vandenbulcke, M., et al. (2015) · The Lancet Neurology · doi:10.1016/s1474-4422(15)00133-7 · Cited by 152 · see citing works

<i>ABCA7</i> frameshift deletion associated with Alzheimer disease in African Americans

Cukier, H. N., Kunkle, B. W., Vardarajan, B. N., Rolati, S., Hamilton-Nelson, K. L., Kohli, M. A., Whitehead, P. L., Dombroski, B. A., Van Booven, D., Lang, R., et al. (2016) · Neurology Genetics · doi:10.1212/nxg.0000000000000079 · Cited by 100 · see citing works

An intronic VNTR affects splicing of ABCA7 and increases risk of Alzheimer’s disease

On Behalf of the BELNEU Consortium, De Roeck, A., Duchateau, L., Van Dongen, J., Cacace, R., Bjerke, M., Van den Bossche, T., Cras, P., Vandenberghe, R., De Deyn, P. P., et al. (2018) · Acta Neuropathologica · doi:10.1007/s00401-018-1841-z · Cited by 93 · see citing works

Amyloid-beta uptake by blood monocytes is reduced with ageing and Alzheimer’s disease

Chen, S.-H., Tian, D.-Y., Shen, Y.-Y., Cheng, Y., Fan, D.-Y., Sun, H.-L., He, C.-Y., Sun, P.-Y., Bu, X.-L., Zeng, F., et al. (2020) · Translational Psychiatry · doi:10.1038/s41398-020-01113-9 · Cited by 89 · see citing works

Deleterious ABCA7 mutations and transcript rescue mechanisms in early onset Alzheimer’s disease

On behalf of the European Early-Onset Dementia (EU EOD) consortium, De Roeck, A., Van den Bossche, T., van der Zee, J., Verheijen, J., De Coster, W., Van Dongen, J., Dillen, L., Baradaran-Heravi, Y., Heeman, B., et al. (2017) · Acta Neuropathologica · doi:10.1007/s00401-017-1714-x · Cited by 74 · see citing works

Genetic risk factors for Alzheimer disease: emerging roles of microglia in disease pathomechanisms

Takatori, S., Wang, W., Iguchi, A., & Tomita, T. (2019) · Advances in Experimental Medicine and Biology · doi:10.1007/978-3-030-05542-4_5 · Cited by 44 · see citing works

High-density lipoprotein-related cholesterol metabolism in Alzheimer's disease

Pedrini, S., Chatterjee, P., Hone, E., & Martins, R. N. (2021) · Journal of Neurochemistry · doi:10.1111/jnc.15170 · Cited by 22 · see citing works

Casual Genes of Schizophrenia Detected by Genome-Wide Association Study (GWAS)

栄, 高. (2014) · Journal of Nihon University Medical Association · doi:10.4264/numa.73.106

Evaluating three strategies of genome‐wide association analysis for integrating data from multiple populations

Zhong, Z., Li, G., Xu, Z., Zeng, H., Teng, J., Feng, X., Diao, S., Gao, Y., Li, J., & Zhang, Z. (2024) · Animal Genetics · doi:10.1111/age.13394 · Cited by 5 · see citing works

Alcohol Dependence Genetics: Lessons Learned From Genome-Wide Association Studies (GWAS) and Post-GWAS Analyses

Hart, A. B., & Kranzler, H. R. (2015) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.12792 · Cited by 119 · see citing works

A genome-wide association study (GWAS) for myopia susceptibility in chicks

Huang, Y. S., Kee, C., Yip, S. P., et al. (2017) · Investigative Ophthalmology & Visual Science

Genome-wide studies of primary open-angle glaucoma

Eliseeva, N., & Churnosov, M. I. (2020) · Russian Annals of Ophthalmology · doi:10.17116/oftalma2020136051129 · Cited by 7 · see citing works