The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.
The inflammatory markers CRP, IL-6, and IL-10 are associated with cognitive function—data from the Berlin Aging Study II
Abstract
Inflammation may be an underlying mechanism in cognitive decline. The present study investigated the relationship between cognitive function and the inflammatory markers C-reactive protein (CRP), interleukin (IL)-6, and IL-10 in a nonclinical sample of elderly adults. Serum levels of CRP, IL-6, and IL-10 were measured in n = 1312 elderly adults (60-85 years, 50.5% females) who underwent comprehensive neuropsychological testing. Multiple linear regression analysis was conducted and adjusted for various demographic and clinical factors. Levels of IL-6, IL-10, and CRP were negatively associated with a composite score of executive function and processing speed, whereas the IL-6 to IL-10 ratio was not predictive for executive function and processing speed. No associations were found between inflammatory markers and verbal episodic memory. These findings suggest a relationship between higher proinflammatory and anti-inflammatory activation of the innate immune system and executive function within the normal range. Further research is needed to examine the relevance of an inflammatory pathway as a potential therapeutic target.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“In humans, the distinguishing criteria for normal vs pathological aging are: central nervous system (CNS) injury, amyloid plaques (based on positron emission tomography (PET)), neurodegeneration, neuropsychiatric conditions, dementia, and impaired performance on cognitive tests (Arani et al, 2015;Fabbri et al, 2016;Tegeler et al, 2016).”
From Microglia Priming with Aging and Stress (2017) · cites this paper as Tegeler et al, 2016
In the citing paper
“For instance, a recent cross-sectional study investigating the association between inflammatory markers and executive functioning in an elderly population indicated an age-associated increase in the serum expression of C-reactive protein (CRP), IL-6 and IL-10.Elevated levels of these cytokines were inversely associated with executive performance on neuropsychological tests (Tegeler et al, 2016).”
From Microglia Priming with Aging and Stress (2017) · cites this paper as Tegeler et al, 2016
Citations
Cites
The CES-D Scale: A Self-Report Depression Scale for Research in the General Population
Radloff, L. S. (1977) · Applied Psychological Measurement · doi:10.1177/014662167700100306 · Cited by 53,267
Discovering Statistics Using SPSS
Field, A. P., & Miles, J. N. V. (2000) · Medical Entomology and Zoology · Cited by 28,269
A compendium of neuropsychological tests: administration, norms, and commentary
(1991) · Choice Reviews Online · doi:10.5860/choice.29-2400 · Cited by 6,118
A Compendium of Neuropsychological Tests: Administration, Norms, and Commentary
Levin, H. S. (1993) · Archives of Neurology · doi:10.1001/archneur.1993.00540050007005 · Cited by 4,796
The Neuropsychological Assessment
Ogden, J. A. (2005) · Oxford University Press eBooks · doi:10.1093/oso/9780195171358.003.0002 · Cited by 4,382
Chronic Subclinical Inflammation as Part of the Insulin Resistance Syndrome
Festa, A., D’Agostino, R., Howard, G., Mykkänen, L., Tracy, R. P., & Haffner, S. M. (2000) · Circulation · doi:10.1161/01.cir.102.1.42 · Cited by 2,366
Assessment of executive functions: Review of instruments and identification of critical issues.
CHAN, R., SHUM, D., TOULOPOULOU, T., & CHEN, E. (2008) · Archives of Clinical Neuropsychology · doi:10.1016/j.acn.2007.08.010 · Cited by 1,401
Age-associated cognitive decline
Deary, I. J., Corley, J., Gow, A. J., Harris, S. E., Houlihan, L. M., Marioni, R. E., Penke, L., Rafnsson, S. B., & Starr, J. M. (2009) · British Medical Bulletin · doi:10.1093/bmb/ldp033 · Cited by 1,295
The metabolic syndrome, inflammation, and risk of cognitive decline
Yaffe, K. (2004) · JAMA · doi:10.1001/jama.292.18.2237 · Cited by 1,025
Cardiovascular risk factors and cognitive decline in middle-aged adults
Knopman, D., Boland, L. L., Mosley, T., Howard, G., Liao, D., Szklo, M., McGovern, P., & Folsom, A. R. (2001) · Neurology · doi:10.1212/wnl.56.1.42 · Cited by 883
Cited by
Sorted by citations
Microglia Priming with Aging and Stress
Niraula, A., Sheridan, J. F., & Godbout, J. P. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2016.185 · Cited by 398
Liu, X., Ma, Y., Ouyang, R., Zeng, Z., Zhan, Z., Lu, H., Cui, Y., Dai, Z., Luo, L., He, C., et al. (2020) · Journal of Neuroinflammation · doi:10.1186/s12974-020-01905-2 · Cited by 249
Sungkarat, S., Boripuntakul, S., Kumfu, S., Lord, S., & Chattipakorn, N. (2018) · Neurorehabilitation and Neural Repair · doi:10.1177/1545968317753682 · Cited by 167
Tang, Y., Fung, E., Xu, A., & Lan, H. Y. (2017) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/1440-1681.12758 · Cited by 146
Systemic Inflammation Mediates Age-Related Cognitive Deficits
Lin, T., Liu, G. A., Perez, E., Rainer, R. D., Febo, M., Cruz-Almeida, Y., & Ebner, N. C. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2018.00236 · Cited by 138
Progression of cognitive decline before and after incident stroke
Zheng, F., Yan, L., Zhong, B., Yang, Z., & Xie, W. (2019) · Neurology · doi:10.1212/wnl.0000000000007716 · Cited by 136
Potential Biomarkers for Post-Stroke Cognitive Impairment: A Systematic Review and Meta-Analysis
Kim, K. Y., Shin, K. Y., & Chang, K. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23020602 · Cited by 139
Microglia in Aging and Alzheimer’s Disease: A Comparative Species Review
Edler, M. K., Mhatre-Winters, I., & Richardson, J. R. (2021) · Cells · doi:10.3390/cells10051138 · Cited by 126
Lyon, D., Cohen, R. A., Chen, H., Kelly, D. L., McCain, N. L., Starkweather, A. R., Ahn, H. B., Sturgill, J., & Jackson‐Cook, C. K. (2016) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2016.11.002 · Cited by 112
High-sensitivity C-reactive protein and cognitive decline: the English Longitudinal Study of Ageing
Zheng, F., & Xie, W. (2017) · Psychological Medicine · doi:10.1017/s0033291717003130 · Cited by 103
Protein-C Reactive as Biomarker Predictor of Schizophrenia Phases of Illness? A Systematic Review
Orsolini, L., Sarchione, F., Vellante, F., Fornaro, M., Matarazzo, I., Martinotti, G., Valchera, A., Nicola, M. D., Carano, A., Giannantonio, M. D., et al. (2018) · Current Neuropharmacology · doi:10.2174/1570159x16666180119144538 · Cited by 102
Thompson, K. I., Chau, M., Lorenzetti, M. S., Hill-Bowen, L. D., Fins, A. I., & Tartar, J. L. (2022) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2022.945661 · Cited by 123
Glaucoma: from pathogenic mechanisms to retinal glial cell response to damage
Fernández‐Albarral, J. A., Ramirez, A. I., de Hoz, R., Matamoros, J. A., Salobrar‐García, E., Elvira‐Hurtado, L., López‐Cuenca, I., Sánchez-Puebla, L., Salazar, J. J., & Ramirez, J. M. (2024) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2024.1354569 · Cited by 105
Protective Effects of Sesamol on Systemic Inflammation and Cognitive Impairment in Aging Mice
Ren, B., Yuan, T., Zhang, X., Wang, L., Pan, J., Liu, Y., Zhao, B., Zhao, W., Liu, Z., & Liu, X. (2020) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.9b07598 · Cited by 68
Beydoun, M. A., Dore, G. A., Canas, J. A., Liang, H., Beydoun, H. A., Evans, M. K., & Zonderman, A. B. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2018.00313 · Cited by 67
Gao, X., Coull, B. A., Lin, X., Vokonas, P., Spiro, A., Hou, L., Schwartz, J. D., & Baccarelli, A. (2021) · Nature Aging · doi:10.1038/s43587-021-00060-4 · Cited by 67
Wennberg, A. M. V., Hagen, C. E., Machulda, M. M., Knopman, D. S., Petersen, R. C., & Mielke, M. M. (2018) · The Journals of Gerontology Series A · doi:10.1093/gerona/gly217 · Cited by 64
Body mass and cognitive decline are indirectly associated via inflammation among aging adults
Bourassa, K., & Sbarra, D. A. (2017) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2016.09.023 · Cited by 61
Manji, Z., Rojas, A., Wang, W., Dingledine, R. J., Varvel, N. H., & Ganesh, T. (2019) · Journal of Alzheimer s Disease · doi:10.3233/jad-180678 · Cited by 65
Chen, J., Doyle, M. F., Fang, Y., Mez, J., Crane, P. K., Scollard, P., ADSP Data Harmonization Consortium Cognitive Harmonization Core, Satizabal, C. L., Alosco, M. L., Qiu, W. Q., et al. (2023) · Aging Cell · doi:10.1111/acel.13955 · Cited by 56
Sleep disturbances and inflammatory biomarkers in schizophrenia: focus on sex differences
Lee, E. E., Ancoli-Israel, S., Eyler, L. T., Tu, X. M., Palmer, B. W., Irwin, M. R., & Jeste, D. V. (2019) · The American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2018.09.017 · Cited by 58
Inflammaging and Brain: Curcumin and Its Beneficial Potential as Regulator of Microglia Activation
Cianciulli, A., Calvello, R., Ruggiero, M., & Panaro, M. A. (2022) · Molecules · doi:10.3390/molecules27020341 · Cited by 60
Zhang, D., Li, N., Wang, Y., Lu, W., Zhang, Y., Chen, Y., Deng, X., & Yu, X. (2019) · International Immunopharmacology · doi:10.1016/j.intimp.2019.03.003 · Cited by 58
Cognitive Impairment in Adult Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis
Hopkins, C. W. P., Powell, N., Norton, C., Dumbrill, J. L., Hayee, B., & Moulton, C. D. (2021) · Journal of the Academy of Consultation-Liaison Psychiatry · doi:10.1016/j.psym.2020.10.002 · Cited by 57
Fard, M. T., Savage, K. M., & Stough, C. K. K. (2022) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2022.105870 · Cited by 56
Predictors of cognitive decline in older individuals without dementia: An updated meta‐analysis
Feng, L., Wang, Y., Zeng, D., Wang, M., & Duan, X. (2023) · Annals of Clinical and Translational Neurology · doi:10.1002/acn3.51740 · Cited by 52
Inflammation, Cognition, and White Matter in Older Adults: An Examination by Race
Boots, E. A., Castellanos, K. J., Zhan, L., Barnes, L. L., Tussing-Humphreys, L. M., Deoni, S., & Lamar, M. (2020) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2020.553998 · Cited by 50
Tian, H., Li, G., Xu, G., Liu, J., Wan, X., Zhang, J., Xie, S., Cheng, J. R., & Gao, S. (2020) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-020-01128-9 · Cited by 52
Vitamin K status and inflammation are associated with cognition in older Irish adults
Kiely, A.-M., Ferland, G., Ouliass, B., O’Toole, P. W., Purtill, H., & O’Connor, E. M. (2018) · Nutritional Neuroscience · doi:10.1080/1028415x.2018.1536411 · Cited by 51
Titus, J., Bray, N. W., Kamkar, N., Camicioli, R. M., Nagamatsu, L. S., Speechley, M. R., & Montero‐Odasso, M. (2021) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2021.111431 · Cited by 51
Cytokines are associated with longitudinal changes in cognitive performance among urban adults
Beydoun, M. A., Weiss, J., Obhi, H. K., Beydoun, H. A., Dore, G. A., Liang, H., Evans, M. K., & Zonderman, A. B. (2019) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2019.04.027 · Cited by 45
Common Pathogenetic Mechanisms Underlying Aging and Tumor and Means of Interventions
Shen, W., He, J., Hou, T., Si, J., & Chen, S. (2022) · Aging and Disease · doi:10.14336/ad.2021.1208 · Cited by 45
Cellular mechanisms in brain aging: Focus on physiological and pathological aging
Aguilar‐Hernández, L., Alejandre‐Aguilar, R., Morales‐Medina, J. C., Iannitti, T., & Flores, G. (2022) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2022.102210 · Cited by 45
Sleep, inflammation and cognitive function in middle-aged and older adults: A population-based study
Hu, M., Shu, X., Feng, H., & Xiao, L. D. (2021) · Journal of Affective Disorders · doi:10.1016/j.jad.2021.02.013 · Cited by 42
New neovascular age‐related macular degeneration is associated with systemic leucocyte activity
Subhi, Y., & Sørensen, T. L. (2016) · Acta Ophthalmologica · doi:10.1111/aos.13330 · Cited by 38
Németh, E., Vig, K., Rácz, K., Koritsánszky, K. B., Ronkay, K. I., Hamvas, F. P., Borbély, C., Eőry, A., Merkely, B. P., & Gál, J. (2017) · BMC Anesthesiology · doi:10.1186/s12871-017-0408-1 · Cited by 38
Cardiometabolic dysregulation and cognitive decline: potential role of depressive symptoms
Schmitz, N., Deschênes, S. S., Burns, R. J., Danna, S. M., Franco, O. H., Ikram, M. A., Mika Kivimaki, B., Singh‐Manoux, A., & Tiemeier, H. W. (2018) · The British Journal of Psychiatry · doi:10.1192/bjp.2017.26 · Cited by 37
Hartman, S. J., Weiner, L. S., Nelson, S. H., Natarajan, L., Patterson, R. E., Palmer, B. W., Parker, B. A., & Sears, D. D. (2019) · JMIR Cancer · doi:10.2196/13150 · Cited by 34
Serre-Miranda, C., Roque, S., Santos, N. C., Costa, P., Sousa, N., Palha, J. A., & Correia‐Neves, M. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.02045 · Cited by 32
Immune senescence and biomarkers profile of Bambuí aged population-based cohort
Torres, K. C. L., Rezende, V. B. D., Lima-Silva, M. L., Santos, L. J. D. S., Costa, C. G., Mambrini, J. V. D. M., Peixoto, S. V., Tarazona-Santos, E., Martins Filho, O. A., Lima-Costa, M. F., et al. (2018) · Experimental Gerontology · doi:10.1016/j.exger.2017.12.006 · Cited by 30
Cognitive Impairment in Zambians With HIV Infection and Pulmonary Tuberculosis
Hestad, K. A., Chinyama, J., Anitha, M. J., Ngoma, M. S., McCutchan, J. A., Franklin, D. R., & Heaton, R. K. (2018) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000001880 · Cited by 28
Adewuyi, E. O., O’Brien, E. K., Porter, T., & Laws, S. M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232416199 · Cited by 34
Spooner, R. K., Taylor, B. K., Moshfegh, C. M., Ahmad, I. M., Dyball, K. N., Emanuel, K. M., Schlichte, S. L., Schantell, M. D., May, P. E., O’Neill, J., et al. (2021) · EBioMedicine · doi:10.1016/j.ebiom.2021.103487 · Cited by 28
Chen, R., Zhao, B., Huang, J., Zhang, M., Wang, Y., Fu, J., Liang, H., & Zhan, H. (2024) · The Journal of Prevention of Alzheimer s Disease · doi:10.14283/jpad.2024.65 · Cited by 30
Klinedinst, B. S., Pappas, C. A., Le, S. T., Yu, S., Wang, Q., Wang, L., Allenspach‐Jorn, K., Mochel, J. P., & Willette, A. A. (2019) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2019.09.008 · Cited by 28
Fard, M. T., Cribb, L., Nolidin, K., Savage, K. M., Wesnes, K. A., & Stough, C. K. K. (2020) · Behavioural Brain Research · doi:10.1016/j.bbr.2020.112502 · Cited by 28
Mekli, K., Lophatananon, A., Maharani, A., Nazroo, J. Y., & Muir, K. R. (2023) · PLoS ONE · doi:10.1371/journal.pone.0288045 · Cited by 28
Inflammatory Markers Associated with Physical Frailty and Cognitive Impairment
Pan, Y., & Ma, L. (2024) · Aging and Disease · doi:10.14336/ad.2024.0258 · Cited by 29
Benedetto, S. D., Gaetjen, M., & Müller, L. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20040990 · Cited by 27
T cell phenotypes associated with insulin resistance: results from the Berlin Aging Study II
Sbierski‐Kind, J., Goldeck, D., Buchmann, N., Spranger, J., Volk, H., Steinhagen‐Thiessen, E., Pawelec, G., Demuth, I., & Spira, D. (2020) · Immunity & Ageing · doi:10.1186/s12979-020-00211-y · Cited by 27
Self-citationWang, J., Xu, H., Wang, D., Wei, G., Zhou, H., Wang, L., Zhou, Y., & Zhang, X. (2020) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2020.10.021 · Cited by 27
Dyer, A. H., McNulty, H., Caffrey, A., Gordon, S., Laird, E. J., Hoey, L., Hughes, C., Ward, M., Strain, J., O’Kane, M., et al. (2023) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2023.11.008 · Cited by 27
Relationship between Lipoprotein (a) and cognitive function – Results from the Berlin Aging Study II
Rohr, F., Bucholtz, N., Toepfer, S., Norman, K., Spira, D., Steinhagen‐Thiessen, E., Lill, C. M., Bertram, L., Demuth, I., Buchmann, N., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-66783-3 · Cited by 26
Self-citationBoots, E. A., Feinstein, D. L., Leurgans, S. E., Aiken‐Morgan, A. T., Fleischman, D. A., Lamar, M., & Barnes, L. L. (2022) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2022.04.014 · Cited by 26
Purpose in life and markers of immunity and inflammation: Testing pathways of episodic memory
Sutin, A., Stephan, Y., Luchetti, M., & Terracciano, A. (2023) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2023.111487 · Cited by 23
Reddan, J. M., White, D., Macpherson, H., Scholey, A. B., & Pipingas, A. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2018.00049 · Cited by 29
Chromosomal and gonadal factors regulate microglial sex effects in the aging brain
Ocañas, S. R., Ansere, V. A., Kellogg, C. M., Isola, J. V. V., Chucair‐Elliott, A. J., & Freeman, W. M. (2023) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2023.02.008 · Cited by 25
Natale, G., Clouston, S., & Smith, D. M. (2021) · The Journals of Gerontology Series A · doi:10.1093/gerona/glab282 · Cited by 21
Gopčević, K., Gkaliagkousi, Ε., Nemcsik, J., Acet, Ö., Bernal-López, M. R., Bruno, R. M., Climie, R. E., Fountoulakis, N., Fraenkel, E., Lazaridis, A. A., et al. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.789690 · Cited by 25
Stredny, C. M., Rotenberg, A., Leviton, A., & Loddenkemper, T. (2022) · Epilepsia Open · doi:10.1002/epi4.12684 · Cited by 21
Griseta, C., Battista, P., Castellana, F., Colonna, I., Sciarra, S., Zupo, R., Bortone, I., Lampignano, L., Tirelli, S., Berardino, G., et al. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e13972 · Cited by 21
Immunity impacts cognitive deficits across neurological disorders
Shaw, B. C., Anders, V., Tinkey, R. A., Habean, M. L., Brock, O. D., Frostino, B. J., & Williams, J. L. (2023) · Journal of Neurochemistry · doi:10.1111/jnc.15999 · Cited by 27
Zhou, H., Lü, J., Shen, Y., Kang, S., & Zong, Y. (2017) · Clinical Neurology and Neurosurgery · doi:10.1016/j.clineuro.2017.06.012 · Cited by 21
Fiocco, A. J., Krieger, L., D’Amico, D., Parrott, M. D., Laurin, D., Gaudreau, P., Greenwood, C., & Ferland, G. (2019) · Ageing Research Reviews · doi:10.1016/j.arr.2019.04.008 · Cited by 21
Benedetto, S. D., Müller, L., Rauskolb, S., Sendtner, M., Fassnacht, M., Pawelec, G., & Müller, V. (2019) · Immunity & Ageing · doi:10.1186/s12979-019-0171-x · Cited by 20
Self-citationBravo, J., Magalhães, C., Andrade, E. B., Magalhães, A., & Summavielle, T. (2023) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2023.1109611 · Cited by 20
Dietz, S. M., Schantell, M. D., Spooner, R. K., Sandal, M. E., Mansouri, A., Arif, Y., Okelberry, H. J., John, J. A., Glesinger, R. J., May, P. E., et al. (2023) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2023.09.012 · Cited by 20
Association of sudden sensorineural hearing loss with dementia: a nationwide cohort study
Tai, S., Shen, C.-T., Wang, L., & Chien, C. (2021) · BMC Neurology · doi:10.1186/s12883-021-02106-x · Cited by 22
Personality and Cognition: The Mediating Role of Inflammatory Markers
Stéphan, Y., Sutin, A. R., Luchetti, M., Aschwanden, D., & Terracciano, A. (2023) · The Journals of Gerontology Series B · doi:10.1093/geronb/gbad152 · Cited by 19
Singhaarachchi, P. H., Antal, P., Calon, F., Culmsee, C., Delpech, J.-C., Feldotto, M., Geertsema, J., Hoeksema, E. E., Kőrösi, A., Layé, S., et al. (2024) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2024.105724 · Cited by 20
Duivon, M., Lequesne, J., Meglio, A. D., Pradon, C., Vaz-Luís, I., Martin, A., Everhard, S., Broutin, S., Rigal, O., Bousrih, C., et al. (2024) · Breast Cancer Research · doi:10.1186/s13058-024-01850-5 · Cited by 18
Lawrence, M. R., Arnetz, J. E., Counts, S., Ahmed, A., & Arnetz, B. B. (2025) · PLoS ONE · doi:10.1371/journal.pone.0315486 · Cited by 16
Adamowicz, D. H., Shilling, P. D., Palmer, B. W., Nguyen, T. T., Wang, E., Liu, C., Tu, X. M., Jeste, D. V., Irwin, M. R., & Lee, E. (2022) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2022.02.029 · Cited by 17
Agostini, A., Benuzzi, F., Ballotta, D., Rizzello, F., Gionchetti, P., & Filippini, N. (2023) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izad029 · Cited by 17
Mingxing, T., Wu, Y., Liang, J., Yang, S., Huang, Z., Hu, J., Yang, Q., Liu, F., & Li, S. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1457348 · Cited by 15
Zheng, Y., Cai, X., Wang, D., Chen, X., Wang, T., Xie, Y., Li, H., Wang, T., He, Y., Li, J., et al. (2024) · BMC Psychiatry · doi:10.1186/s12888-024-06054-x · Cited by 17
Nguyen, A. W., Taylor, H. O., Lincoln, K. D., Qin, W., Hamler, T. C., Wang, F. “., & Mitchell, U. A. (2021) · The Journals of Gerontology Series A · doi:10.1093/gerona/glab121 · Cited by 13
Cognitive and mental health outcomes in long covid
Aretouli, E., Malik, M., Widmann, C., Parker, A. M., Oh, E. S., & Vannorsdall, T. D. (2025) · BMJ · doi:10.1136/bmj-2024-081349 · Cited by 21
Snyder, A., Grant, H. E., Chou, A., Lindbergh, C. A., Kramer, J. H., Miller, B. L., & Elahi, F. M. (2023) · Alzheimer s & Dementia · doi:10.1002/alz.12956 · Cited by 13
Age-Related Colonic Mucosal Microbiome Community Shifts in Monkeys
Vemuri, R., Sherrill, C., Davis, M. A., & Kavanagh, K. (2020) · The Journals of Gerontology Series A · doi:10.1093/gerona/glaa256 · Cited by 15
Davidson-Turner, K., Farina, M. P., & Hayward, M. D. (2024) · Biodemography and Social Biology · doi:10.1080/19485565.2024.2356672 · Cited by 11
Takasugi, S., Iimura, S., Yasuda, M., Saito, Y., & Morifuji, M. (2025) · Microorganisms · doi:10.3390/microorganisms13010185 · Cited by 14
Rocha‐Gomes, A., Teixeira, A. E., Santiago, C. M. O., de Oliveira, D. G., da Silva, A. A., Lacerda, A. C. R., Riul, T. R., Mendonça, V. A., Rocha‐Vieira, E., & Leite, H. R. (2021) · Physiology & Behavior · doi:10.1016/j.physbeh.2021.113628 · Cited by 12
Inflammatory Markers and Episodic Memory Functioning in Depressive Disorders
Wachowska, K., Szemraj, J., Śmigielski, J., & Gałecki, P. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11030693 · Cited by 13
Watson, I., Brüne, M., & Bradley, A. J. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.05.010 · Cited by 14
Galinha, I. C., Pinal, D., Lima, M. L., & Palmeira, A. L. (2021) · Psychosocial Intervention · doi:10.5093/pi2021a3 · Cited by 13
Yin, M., Heng, Z., Li, J., Wang, L., Zhu, M., Wang, N., Yang, P., & Yang, Z. (2025) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2025.02.062 · Cited by 13
Xiao, L., Ge, B., Chen, X., Chen, B., Qin, L., Hu, X., Pan, H., Chen, Y., Tian, L., Gao, Y., et al. (2019) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2019.00033 · Cited by 10
Zhu, J., Hu, W., Zhou, Y., Qiao, J., Chang, X., & Tong, Z. (2019) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2019.152118 · Cited by 10
Dalkner, N., Reininghaus, E. Z., Schwalsberger, K., Rieger, A., Hamm, C., Pilz, R., Lenger, M., Queissner, R., Falzberger, V. S., Platzer, M., et al. (2020) · Nutrients · doi:10.3390/nu12103019 · Cited by 12
Patel, R. A., Wharton, W., Bay, A. A., Ni, L., Barter, J., & Hackney, M. E. (2020) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/13803395.2020.1798879 · Cited by 9
Soria-Comes, T., Abril, V. P., Ureste, M. M., Sánchez, J. G., Buades, J. M., Llavador, M. J. F., Gabaldón, A. L., Jurado, M. G., & Maestu, I. (2020) · Translational Cancer Research · doi:10.21037/tcr-20-1997 · Cited by 9
Ekström, I., Vetrano, D. L., Papenberg, G., & Laukka, E. J. (2021) · i-Perception · doi:10.1177/20416695211009928 · Cited by 8
Subjective age and multiple cognitive domains in two longitudinal samples
Stéphan, Y., Sutin, A. R., Luchetti, M., Aschwanden, D., & Terracciano, A. (2021) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2021.110616 · Cited by 9
Ilari, S., Russo, P., Proietti, S., Vitiello, L., Muscoli, C., Tomino, C., Milić, M., & Bonassi, S. (2022) · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · doi:10.1016/j.mrgentox.2022.503499 · Cited by 9
Inflammatory Cytokines and Cognition in Alzheimer’s Disease and Its Prodrome
Seong, S. J., Kim, K. W., Song, J. Y., Park, K. J., Jo, Y. T., Han, J. H., Yoo, K. H., Jo, H. J., & Hwang, J. Y. (2024) · Psychiatry Investigation · doi:10.30773/pi.2024.0071 · Cited by 8
Hallab, A., O'Bryant, S. E., Yaffe, K., Toga, A. W., Rissman, R., Johnson, L., Braskie, M. N., King, K., Hall, J. R., Petersen, M., et al. (2025) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2025.101031 · Cited by 8
Souza‐Talarico, J. N., Perkhounkova, Y., Hein, M., Lee, J., Hefti, M. M., & Sindi, S. (2025) · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring · doi:10.1002/dad2.70140 · Cited by 9
Tejera, C. H., Ware, E. B., Hicken, M. T., Kobayashi, L. C., Wang, H., Adkins‐Jackson, P. A., Blostein, F., Zawistowski, M., Mukherjee, B., & Bakulski, K. M. (2024) · Communications Medicine · doi:10.1038/s43856-024-00569-w · Cited by 11
Fromme, S. E., Joergens, S., Schwarte, K., Hohoff, C., Dietrich, D. E., & Baune, B. T. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.12.097 · Cited by 8
Metadata
- Authors
- Tegeler, C., O'Sullivan, J. L., Bucholtz, N., Goldeck, D., Pawelec, G., Steinhagen-Thiessen, E., & Demuth, I.
- Affiliations
- Charité – Universitätsmedizin Berlin (DE)
- University of Tübingen (DE)
- Corresponding author
- Tegeler, Christina
- Demuth, Ilja
- Venue
- Neurobiology of Aging
- Publisher
- Elsevier BV
- Published
- 2016-02
- Volume
- 38
- Pages
- 112-117
- ISSN
- 0197-4580 (ISSN-L)
- OpenAlex
- W2167109574
- Cited by
- 163
- References
- 42
- Citations by year
- 2026: 14 · 2025: 19 · 2024: 23 · 2023: 20 · 2022: 14 · 2021: 19 · 2020: 18 · 2019: 13 · 2018: 10 · 2017: 7 · 2016: 6
- FWCI
- 6.23
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Neurobiology of Aging (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Bundesministerium für Bildung und Forschung (16SV5536K)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Life Sciences › Neuroscience › Biological Psychiatry › Tryptophan and brain disorders
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Keywords
- C-reactive protein, interleukin-6, IL-10, inflammation, cognitive function, executive function, processing speed, verbal episodic memory, cognitive decline, older adults, innate immune system
- MeSH terms
- Aged, Aged, 80 and over, C-Reactive Protein, Cognition, Female, Humans, Immunity, Innate, Male, Middle Aged, Interleukin-6, Linear Models, Interleukin-10, Inflammation Mediators, Executive Function
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review