Pawelec, Graham

Immune evasion in cancer: mechanistic basis and therapeutic strategies

Vinay, D. S., Ryan, E. P., Pawelec, G., Talib, W. H., Stagg, J., Elkord, E., Lichtor, T., Decker, W. K., Whelan, R. L., Kumara, H. M. C. S., et al. (2015) · Seminars in Cancer Biology

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 1,625

Aging in COVID-19: Vulnerability, immunity and intervention

Chen, Y., Klein, S. L., Garibaldi, B. T., Li, H., Wu, C., Osevala, N. M., Li, T., Margolick, J. B., Pawelec, G., & Leng, S. X. (2021) · Ageing Research Reviews

COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 Research

Cited by 1,007

Age and immunity: What is “immunosenescence”?

Pawelec, G. (2018) · Experimental Gerontology

T-cell and B-cell ImmunologyTelomeres, Telomerase, and Senescence

Cited by 606

Baseline Peripheral Blood Biomarkers Associated with Clinical Outcome of Advanced Melanoma Patients Treated with Ipilimumab

Martens, A., Wistuba-Hamprecht, K., Foppen, M. G., Yuan, J., Postow, M. A., Wong, P., Romano, E., Khammari, A., Dreno, B., Capone, M., et al. (2016) · Clinical Cancer Research

Cancer Immunotherapy and BiomarkersCutaneous Melanoma Detection and Management

Cited by 541

Epigenetic and immune function profiles associated with posttraumatic stress disorder

Uddin, M., Aiello, A. E., Wildman, D. E., Koenen, K. C., Pawelec, G., de los Santos, R., Goldmann, E., & Galea, S. (2010) · Proceedings of the National Academy of Sciences

Posttraumatic Stress Disorder ResearchEpigenetics and DNA Methylation

Cited by 518

Immunology of aging: the birth of inflammaging

Fulop, T., Larbi, A., Pawelec, G., Khalil, A., Cohen, A. A., Hirokawa, K., Witkowski, J. M., & Franceschi, C. (2021) · Clinical Reviews in Allergy & Immunology

Genetics, Aging, and Longevity in Model OrganismsImmune Response and Inflammation

Cited by 464

A Consideration of Biomarkers to be Used for Evaluation of Inflammation in Human Nutritional Studies

Calder, P. C., Ahluwalia, N., Albers, R., Bosco, N., Bourdet-Sicard, R., Haller, D., Holgate, S. T., Jönsson, L. S., Latulippe, M. E., Marcos, A., et al. (2013) · British Journal of Nutrition

Adipokines, Inflammation, and Metabolic DiseasesInflammatory Biomarkers in Disease Prognosis

Cited by 425

An Immune Risk Phenotype, Cognitive Impairment, and Survival in Very Late Life: Impact of Allostatic Load in Swedish Octogenarian and Nonagenarian Humans

Wikby, A., Ferguson, F., Forsey, R., Thompson, J., Strindhall, J., Löfgren, S., Nilsson, B.-O., Ernerudh, J., Pawelec, G., & Johansson, B. (2005) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences

Aging and Gerontology ResearchHealth disparities and outcomes

Cited by 407

Human immunosenescence: is it infectious?

Pawelec, G., Akbar, A., Caruso, C., Solana, R., Grubeck‐Loebenstein, B., & Wikby, A. (2005) · Immunological Reviews

Cytomegalovirus and herpesvirus researchImmune responses and vaccinations

Cited by 405

Direct Injection of Protamine-protected mRNA: Results of a Phase 1/2 Vaccination Trial in Metastatic Melanoma Patients

Weide, B., Pascolo, S., Scheel, B., Derhovanessian, E., Pflugfelder, A., Eigentler, T. K., Pawelec, G., Hoerr, I., Rammensee, H.-G., & Garbe, C. (2009) · Journal of Immunotherapy

Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers

Cited by 378

Human T Cell Aging and the Impact of Persistent Viral Infections

Fülöp, T., Larbi, A., & Pawelec, G. (2013) · Frontiers in Immunology

T-cell and B-cell ImmunologyTelomeres, Telomerase, and Senescence

Cited by 347

Immunosenescence and vaccine failure in the elderly

Grubeck-Loebenstein, B., Della Bella, S., Iorio, A. M., Michel, J.-P., Pawelec, G., & Solana, R. (2009) · Aging Clinical and Experimental Research

Immune responses and vaccinationsT-cell and B-cell Immunology

Cited by 269

Hallmarks of human “immunosenescence”: adaptation or dysregulation?

Pawelec, G. (2012) · Immunity & Ageing

T-cell and B-cell ImmunologyImmune responses and vaccinations

Cited by 257

Cytomegalovirus Infection: A Driving Force in Human T Cell Immunosenescence

KOCH, S., LARBI, A., ÖZCELIK, D., SOLANA, R., GOUTTEFANGEAS, C., ATTIG, S., WIKBY, A., STRINDHALL, J., FRANCESCHI, C., & PAWELEC, G. (2007) · Annals of the New York Academy of Sciences

Cytomegalovirus and herpesvirus researchHerpesvirus Infections and Treatments

Cited by 242

The unmet need in the elderly: How immunosenescence, CMV infection, co-morbidities and frailty are a challenge for the development of more effective influenza vaccines

McElhaney, J. E., Zhou, X., Talbot, H. K., Soethout, E., Bleackley, R. C., Granville, D. J., & Pawelec, G. (2012) · Vaccine

Influenza Virus Research StudiesImmune responses and vaccinations

Cited by 229

Biomarkers of human immunosenescence: impact of cytomegalovirus infection

Derhovanessian, E., Larbi, A., & Pawelec, G. (2009) · Current Opinion in Immunology

Cytomegalovirus and herpesvirus researchTelomeres, Telomerase, and Senescence

Cited by 220

No Immune Risk Profile among individuals who reach 100 years of age: Findings from the Swedish NONA immune longitudinal study

Strindhall, J., Nilsson, B.-O., Löfgren, S., Ernerudh, J., Pawelec, G., Johansson, B., & Wikby, A. (2007) · Experimental Gerontology

T-cell and B-cell ImmunologyCytomegalovirus and herpesvirus research

Cited by 209

Role of CMV in immune senescence.

Pawelec, G., & Derhovanessian, E. (2011) · Virus Research

Cytomegalovirus and herpesvirus researchTelomeres, Telomerase, and Senescence

Cited by 201

Increases in Absolute Lymphocytes and Circulating CD4+ and CD8+ T Cells Are Associated with Positive Clinical Outcome of Melanoma Patients Treated with Ipilimumab

Martens, A., Wistuba-Hamprecht, K., Yuan, J., Postow, M. A., Wong, P., Capone, M., Madonna, G., Khammari, A., Schilling, B., Sucker, A., et al. (2016) · Clinical Cancer Research

Cancer Immunotherapy and BiomarkersCutaneous Melanoma Detection and Management

Cited by 180

Immunity, ageing and cancer

Derhovanessian, E., Solana, R., Larbi, A., & Pawelec, G. (2008) · Immunity & Ageing

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 169

The inflammatory markers CRP, IL-6, and IL-10 are associated with cognitive function—data from the Berlin Aging Study II

Tegeler, C., O'Sullivan, J. L., Bucholtz, N., Goldeck, D., Pawelec, G., Steinhagen-Thiessen, E., & Demuth, I. (2016) · Neurobiology of Aging

Dementia and Cognitive Impairment ResearchTryptophan and brain disorders

Cited by 163

Immunosenenescence: role of cytomegalovirus

Pawelec, G. (2014) · Experimental Gerontology

Cytomegalovirus and herpesvirus researchImmune responses and vaccinations

Cited by 163

On the immunological theory of aging

Fulop, T., Witkowski, J. M., Pawelec, G., Alan, C., & Larbi, A. (2014) · Interdisciplinary topics in gerontology and geriatrics

Genetics, Aging, and Longevity in Model OrganismsImmune Response and Inflammation

Cited by 157

New advances in CMV and immunosenescence

Sansoni, P., Vescovini, R., Fagnoni, F. F., Akbar, A., Arens, R., Chiu, Y.-L., Čičin-Šain, L., Dechanet-Merville, J., Derhovanessian, E., Ferrando-Martinez, S., et al. (2014) · Experimental Gerontology

Cytomegalovirus and herpesvirus researchImmune responses and vaccinations

Cited by 150