Cited by 415Transcranial Magnetic Stimulation StudiesElectroconvulsive Therapy StudiesDeep Brain Stimulation and Movement Disorders

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Therapeutic effects of non-invasive brain stimulation with direct currents (tDCS) in neuropsychiatric diseases

Kuo, Min-Fang, Paulus, Walter, Nitsche, Michael A.·2014·NeuroImage

DOI 10.1016/j.neuroimage.2013.05.117

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Abstract

Neuroplasticity, which is the dynamic structural and functional reorganization of central nervous system connectivity due to environmental and internal demands, is recognized as a major physiological basis for adaption of cognition, and behavior, and thus of utmost importance for normal brain function. Pathological alterations of plasticity are increasingly explored as pathophysiological foundation of diverse neurological and psychiatric diseases. Non-invasive brain stimulation techniques (NIBS), such as repetitive transcranial magnetic stimulation (rTMS), and transcranial direct current stimulation (tDCS), are able to induce and modulate neuroplasticity in humans. Therefore, they have potential to alter pathological plasticity on the one hand, and foster physiological plasticity on the other, in neuropsychiatric diseases to reduce symptoms, and enhance rehabilitation. tDCS is an emerging NIBS tool, which induces glutamatergic plasticity via application of relatively weak currents through the scalp in humans. In the last years its efficacy to treat neuropsychiatric diseases has been explored increasingly. In this review, we will give an overview of pathological alterations of plasticity in neuropsychiatric diseases, gather clinical studies involving tDCS to ameliorate symptoms, and discuss future directions of application, with an emphasis on optimizing stimulation effects.

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The Organization of Behavior
Hebb, D. O. (2005) · doi:10.4324/9781410612403 · Cited by 9,825
Long‐lasting potentiation of synaptic transmission in the dentate area of the unanaesthetized rabbit following stimulation of the perforant path
Bliss, T. V. P., & Gardner-Medwin, A. R. (1973) · The Journal of Physiology · doi:10.1113/jphysiol.1973.sp010274 · Cited by 7,424
The organization of behavior.
indicated, N. A. (1950) · Journal of Consulting Psychology · doi:10.1037/h0049612 · Cited by 6,984
Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation
Nitsche, M. A., & Paulus, W. (2000) · The Journal of Physiology · doi:10.1111/j.1469-7793.2000.t01-1-00633.x · Cited by 5,656
Neurocircuitry of Addiction
Koob, G. F., & Volkow, N. D. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.110 · Cited by 5,340
LTP and LTD
Malenka, R. C., & Bear, M. F. (2004) · Neuron · doi:10.1016/j.neuron.2004.09.012 · Cited by 3,968
Transcranial direct current stimulation: State of the art 2008
Nitsche, M. A., Cohen, L. G., Wassermann, E. M., Priori, A., Lang, N., Antal, A., Paulus, W., Hummel, F., Boggio, P. S., Fregni, F., et al. (2008) · Brain Stimulation · doi:10.1016/j.brs.2008.06.004 · Cited by 3,057
Sustained excitability elevations induced by transcranial DC motor cortex stimulation in humans
Nitsche, M. A., & Paulus, W. (2001) · Neurology · doi:10.1212/wnl.57.10.1899 · Cited by 2,617
Decision making, impulse control and loss of willpower to resist drugs: a neurocognitive perspective
Bechara, A. (2005) · Nature Neuroscience · doi:10.1038/nn1584 · Cited by 2,149
Abnormal neural oscillations and synchrony in schizophrenia
Uhlhaas, P. J., & Singer, W. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2774 · Cited by 2,120

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Method
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“Considering the potential effects on neuroplasticity, transcranial direct current stimulation (tDCS) has been evaluated as treatment option in various neuropsychiatric diseases including dementia with mixed results (Kuo et al., 2014).”
Background
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Background
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Background
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“tDCS tDCS is a non-invasive form of neuromodulation that has been demonstrated to modulate a variety of cognitive functions by changing cortical excitability (Kuo et al., 2014; Lefaucheur et al., 2017).”
Background
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“The technique of tDCS has been widely used in understanding brain function, the treatment of neuropsychiatric diseases and it has received increasing attention due to its potential impacts on brain activity in both healthy subjects and patients in the department of rehabilitation (Kuo et al., 2014; Ciullo et al., 2021…”
Method
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“65,66 The development and application of physical factor therapy are continually evolving, aided by advancements in neuroimaging and electrophysiological techniques, which facilitate the effective design of rehabilitation interventions.”
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“Psychiatric tDCS interventions are often aimed at improving disrupted neurobiological processes involved in (working) memory and emotion regulation [15, 16] and usually comprise 5–30 tDCS sessions applied with an interval of one or several days [17].”
Background
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“For instance, TDCS has shown effectiveness for drug-resistant depression [4], chronic pain [3], or stroke recovery [5].”
Background
Transcranial direct current stimulation for global cognition in Alzheimer’s disease: a systemic review and meta-analysis
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“In the previous studies, cognitive function, behavioral, and psychological symptoms of the patients could be altered after tDCS [5, 6].”
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“TDCS can enhance the cognitive–motor function and is beneficial for multiple neurological and psychiatric disorders (e.g., depression and Alzheimer’s disease) (Kuo et al., 2014; Summers et al., 2016).”
Background
Overlapping and distinct neural metabolic patterns related to impulsivity and hypomania in Parkinson’s disease
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“This region could be a potential target for interventions including transcranial direct-current stimulation and transcranial magnetic stimulation to reduce impulsivity and hypomania behaviors (Kuo et al. 2014; Tracy et al. 2015).”
Background
Gamma-band auditory steady-state response after frontal tDCS: A double-blind, randomized, crossover study
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“Jo ur na l P re -p ro of 1 Introduction Transcranial direct current stimulation (tDCS) is a brain stimulation modality currently used to treat patients with neuropsychiatric diseases [1, 2, 3, 4, 5, 6].”
The Effects of Transcranial Direct Current Stimulation (tDCS) and Biofeedback on Proprioception and Functional Balance in Athletes with ACL-deficiency
Jamebozorgi, A. A., Rahimi, A., Daryabor, A., Kazemi, S. M., & Jamebozorgi, F. (2022) · Middle East Journal of Rehabilitation and Health Studies · doi:10.5812/mejrh-130364 · Cited by 9
“The tDCS is a noninvasive and safe method of brain stimulation, that uses low-intensity electrical current directly to desired areas of the brain through electrodes on the skull surface and can alter cortical irritability by modulating the resting potential of the neuronal membrane (23).”
Method
Neurodegenerative diseases
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“1 3 A growing amount of evidence has demonstrated that NIBS is an effective approach to ameliorate a wide range of neurological and psychiatric disorders (Alizadehgoradel et al., 2020; Flöel, 2014; Kuo et al., 2014; Marković et al., 2021; Martin et al., 2017; Salehinejad et al., 2019, 2020; Vicario et al., 2019; Vicar…”
Background
Repeated sessions of bilateral transcranial direct current stimulation on intractable tinnitus: a study protocol for a double-blind randomized controlled trial
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“It has been widely used in cognitive neuroscience to understand brain function and treat neurological disorders (Kuo et al., 2014; Enhancing et al., 2015).”
Background
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“tDCS has been shown to have positive benefits in the treatment of neurological and psychiatric conditions, as well as in the recovery of cognitive, motor, and sensory abilities [29,30].”
BackgroundInfluential
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“The tDCS development within the fields of neurology and cognitive rehabilitation builds upon existing knowledge of animal models and human studies. tDCS has been shown to enhance brain performance and cognitive functions in both healthy individuals and patients (Kuo et al., 2014).”
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“Indeed variability in E/I is described to be relevant to both physiological differences (Jocham et al., 2012) and various neuropsychiatric disorders such as schizophrenia, autism, ADHD (Krause et al., 2013; Kuo et al., 2014; Hill et al., 2016a).”
Background
Effects of anodal multichannel transcranial direct current stimulation (tDCS) on social-cognitive performance in healthy subjects: A randomized sham-controlled crossover pilot study
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Transcranial Direct Current Stimulation (tDCS)
Unal, G., & Bikson, M. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-805353-9.00135-2 · Cited by 7
Effects of transcranial direct current stimulation on cortex modulation by stimulation of the primary motor cortex and parietal cortex in humans
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Small effects of electric field on motor cortical excitability following anodal tDCS
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“Given the implication of alterations of neuroplasticity in pathologic condition such as psychiatric disorders, tDCS might be a promising therapeutic alternative to treatment of such pathological plasticity modification (Kuo et al ., 2014).”
La stimulation transcrânienne à courant continu en psychiatrie
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HD-tDCS over the left DLPFC increases cued recall and subjective question familiarity rather than other aspects of memory and metamemory
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Anodal tDCS of the lower limb M1 does not acutely affect clinical blood pressure and heart rate in healthy and post stroke individuals
Madhavan, S. (2015) · SOJ Neurology · doi:10.15226/2374-6858/2/2/00118 · Cited by 5
How Non-invasive Brain Stimulation Might Invade Our Sphere of Justice
Lavazza, A., & Garasic, M. D. (2017) · Journal of Cognitive Enhancement · doi:10.1007/s41465-017-0008-5 · Cited by 5
“…neuropathic pain, Parkinsonism, stroke recovery, tinnitus, traumatic spinal cord injury, depression, and drug addiction, even though tDCS has not been approved by the FDA for any therapeutic applications and these treatments are presently considered an Boff-label^ application (Kuo et al. 2014).”
Background
Comparison of the Effectiveness of Sertraline, Transcranial Direct Stimulation Current and their Combination on Post-Traumatic Stress Disorder in Veterans
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Modulating the Activity of the VMPFC With tDCS Alters the Social Framing Effect
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“VMPFC activity has been observed for non-costly social decisions (Kuss et al., 2015).”
Background
Personality Traits Modulate the Effect of tDCS on Reading Speed of Social Sentences
Reyes, C., Padrón, I., Yagual, S. N., & Marrero, H. (2021) · Brain Sciences · doi:10.3390/brainsci11111464 · Cited by 5
“Other neuropsychiatric disease in which the use of NIBS has been researched is depression (see [29].”
Background
Rehabilitation Technologies for Cerebral Palsy
Gaebler-Spira, D. J., Peri, E., Lunardini, F., Sánchez-Santed, F., Duff, M., Ballasiotes, M. K., & Raya, R. (2015) · Biosystems & biorobotics · doi:10.1007/978-3-319-24901-8_4 · Cited by 5

Authors: Kuo, M.-F., Paulus, W., & Nitsche, M. A.
Affiliations: Universitätsmedizin Göttingen (DE)
Corresponding author: Nitsche, Michael A.
ORCID: Kuo, Min-Fang
Paulus, Walter
Nitsche, Michael A.
Venue: NeuroImage
Publisher: Elsevier BV
Published: 2014-01
Volume: 85
Pages: 948-960
ISSN: 1053-8119 (ISSN-L)
DOI: 10.1016/j.neuroimage.2013.05.117
OpenAlex: W2057070604
Cited by: 415
References: 149
Citations by year: 2026: 12 · 2025: 18 · 2024: 18 · 2023: 16 · 2022: 22 · 2021: 32 · 2020: 27 · 2019: 29 · 2018: 40 · 2017: 50 · 2016: 55 · 2015: 51 · 2014: 31
FWCI: 4.85
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: NeuroImage (publishedVersion)
PubMed (publishedVersion)
GRO (submittedVersion)
Funders: German Research Society (Ni 683/4-2, Ni 683/6-1)
German Ministry for Education and Research (03IPT605E)
Topics: Life Sciences › Neuroscience › Neurology › Transcranial Magnetic Stimulation Studies
Health Sciences › Medicine › Psychiatry and Mental health › Electroconvulsive Therapy Studies
Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
Keywords: transcranial direct current stimulation, non-invasive brain stimulation, neuroplasticity, neuropsychiatric disorders, stimulation optimization
MeSH terms: Mental Disorders, Electric Stimulation Therapy, Humans, Neuronal Plasticity, Tinnitus, Pain Management

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Therapeutic effects of non-invasive brain stimulation with direct currents (tDCS) in neuropsychiatric diseases

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