The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Peripheral and Central Mechanisms of Itch
Open accessAbstract
Itch is a unique sensory experience that is encoded by genetically distinguishable neurons both in the peripheral nervous system (PNS) and central nervous system (CNS) to elicit a characteristic behavioral response (scratching). Itch interacts with the other sensory modalities at multiple locations, from its initiation in a particular dermatome to its transmission to the brain where it’s finally perceived. In this review, we summarize the current understanding of the molecular and neural mechanisms of itch by starting in the periphery, where itch is initiated and perceived, and discussing the circuits involved in itch processing in the CNS.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Janeway, C. A., & Medzhitov, R. (2002) · Annual Review of Immunology · doi:10.1146/annurev.immunol.20.083001.084359 · Cited by 8,394
Cellular and Molecular Mechanisms of Pain
Basbaum, A. I., Bautista, D. M., Scherrer, G., & Julius, D. (2009) · Cell · doi:10.1016/j.cell.2009.09.028 · Cited by 4,344
Phototransduction by retinal ganglion cells that set the circadian clock
Berson, D. M., Dunn, F. A., & Takao, M. (2002) · Science · doi:10.1126/science.1067262 · Cited by 3,629
Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing
Usoskin, D., Furlan, A., Islam, S., Abdo, H., Lönnerberg, P., Lou, D., Hjerling-Leffler, J., Haeggström, J., Kharchenko, O., Kharchenko, P. V., et al. (2015) · Nature Neuroscience · doi:10.1038/nn.3881 · Cited by 2,136
Sensory Neurons Co-opt Classical Immune Signaling Pathways to Mediate Chronic Itch
Oetjen, L. K., Mack, M. R., Feng, J., Whelan, T. M., Niu, H., Guo, C. J., Chen, S., Trier, A. M., Xu, A. Z., Tripathi, S. V., et al. (2017) · Cell · doi:10.1016/j.cell.2017.08.006 · Cited by 1,092
Origin, homeostasis and function of Langerhans cells and other langerin-expressing dendritic cells
Merad, M., Ginhoux, F., & Collin, M. (2008) · Nature Reviews Immunology · doi:10.1038/nri2455 · Cited by 850
Histamine and H1-antihistamines: Celebrating a century of progress
Simons, F. E. R., & Simons, K. J. (2011) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2011.09.005 · Cited by 541
Joost, S., Zeisel, A., Jacob, T., Sun, X., La Manno, G., Lönnerberg, P., Linnarsson, S., & Kasper, M. (2016) · Cell Systems · doi:10.1016/j.cels.2016.08.010 · Cited by 429
Han, H., Roan, F., & Ziegler, S. F. (2017) · Immunological Reviews · doi:10.1111/imr.12546 · Cited by 285
Cited by
Astrocytes in chronic pain and itch
Ji, R.-R., Donnelly, C. R., & Nedergaard, M. (2019) · Nature Reviews Neuroscience · doi:10.1038/s41583-019-0218-1 · Cited by 538
Physiology and Pathophysiology of Itch
Cevikbas, F., & Lerner, E. A. (2020) · Physiological Reviews · doi:10.1152/physrev.00017.2019 · Cited by 282
A basophil-neuronal axis promotes itch
Wang, F., Trier, A. M., Li, F., Kim, S., Chen, Z., Chai, J. N., Mack, M. R., Morrison, S. A., Hamilton, J. D., Baek, J., et al. (2021) · Cell · doi:10.1016/j.cell.2020.12.033 · Cited by 264
Self-citationThe cellular and molecular basis of somatosensory neuron development
Meltzer, S., Santiago, C., Sharma, N., & Ginty, D. D. (2021) · Neuron · doi:10.1016/j.neuron.2021.09.004 · Cited by 149
Identification of a Spinal Circuit for Mechanical and Persistent Spontaneous Itch
Pan, H., Fatima, M., Li, A., Lee, H., Cai, W., Horwitz, L., Hor, C. C., Zaher, N., Cin, M., Slade, H., et al. (2019) · Neuron · doi:10.1016/j.neuron.2019.06.016 · Cited by 140
Metadata
- Authors
- Dong, X., & Dong, X.
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2018-05
- Volume
- 98
- Issue
- 3
- Pages
- 482-494
- ISSN
- 0896-6273 (ISSN-L)
- OpenAlex
- W2799273224
- Cited by
- 378
- References
- 9
- FWCI
- 31.87
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Peripheral and Central Mechanisms of Itch. https://app.cochat.ai/papers/10.1016/j.neuron.2018.03.023
- The paper
- Dong, X., & Dong, X. (2018). Peripheral and Central Mechanisms of Itch. Neuron. https://doi.org/10.1016/j.neuron.2018.03.023
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.