VIP Interneurons Contribute to Avoidance Behavior by Regulating Information Flow across Hippocampal-Prefrontal Networks

Ultrasensitive fluorescent proteins for imaging neuronal activity

Chen, T.-W., Wardill, T. J., Sun, Y., Pulver, S. R., Renninger, S. L., Baohan, A., Schreiter, E. R., Kerr, R. A., Orger, M. B., Jayaraman, V., et al. (2013) · Nature · doi:10.1038/nature12354 · Cited by 6,474 · see citing works

Parvalbumin neurons and gamma rhythms enhance cortical circuit performance

Sohal, V. S., Zhang, F., Yizhar, O., & Deisseroth, K. (2009) · Nature · doi:10.1038/nature07991 · Cited by 2,606 · see citing works

Natural neural projection dynamics underlying social behavior

Gunaydin, L. A., Grosenick, L., Finkelstein, J. C., Kauvar, I. V., Fenno, L. E., Adhikari, A., Lammel, S., Mirzabekov, J. J., Airan, R. D., Zalocusky, K. A., et al. (2014) · Cell · doi:10.1016/j.cell.2014.05.017 · Cited by 1,389 · see citing works

Inhibition of inhibition in visual cortex: the logic of connections between molecularly distinct interneurons

Pfeffer, C. K., Xue, M., He, M., Huang, Z. J., & Scanziani, M. (2013) · Nature Neuroscience · doi:10.1038/nn.3446 · Cited by 1,353 · see citing works

Concurrent activation of striatal direct and indirect pathways during action initiation

Cui, G., Jun, S. B., Jin, X., Pham, M. D., Vogel, S. S., Lovinger, D. M., & Costa, R. M. (2013) · Nature · doi:10.1038/nature11846 · Cited by 1,260 · see citing works

Dissociable roles of prelimbic and infralimbic cortices, ventral hippocampus, and basolateral amygdala in the expression and extinction of conditioned fear

Sierra-Mercado, D., Padilla-Coreano, N., & Quirk, G. J. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2010.184 · Cited by 1,190 · see citing works

Cortical interneurons that specialize in disinhibitory control

Pi, H.-J., Hangya, B., Kvitsiani, D., Sanders, J. I., Huang, Z. J., & Kepecs, A. (2013) · Nature · doi:10.1038/nature12676 · Cited by 1,136 · see citing works

The subcellular organization of neocortical excitatory connections

Petreanu, L., Mao, T., Sternson, S. M., & Svoboda, K. (2009) · Nature · doi:10.1038/nature07709 · Cited by 1,047 · see citing works

A Cortical Circuit for Gain Control by Behavioral State

Fu, Y., Tucciarone, J. M., Espinosa, J. S., Sheng, N., Darcy, D. P., Nicoll, R. A., Huang, Z. J., & Stryker, M. P. (2014) · Cell · doi:10.1016/j.cell.2014.01.050 · Cited by 937 · see citing works

A disinhibitory circuit mediates motor integration in the somatosensory cortex

Lee, S., Kruglikov, I., Huang, Z. J., Fishell, G., & Rudy, B. (2013) · Nature Neuroscience · doi:10.1038/nn.3544 · Cited by 758 · see citing works

Synchronized activity between the ventral hippocampus and the medial prefrontal cortex during anxiety

Adhikari, A., Topiwala, M. A., & Gordon, J. A. (2010) · Neuron · doi:10.1016/j.neuron.2009.12.002 · Cited by 729 · see citing works

Direct ventral hippocampal-prefrontal input is required for anxiety-related neural activity and behavior

Padilla-Coreano, N., Bolkan, S. S., Pierce, G. M., Blackman, D. R., Hardin, W. D., Garcia-Garcia, A. L., Spellman, T. J., & Gordon, J. A. (2016) · Neuron · doi:10.1016/j.neuron.2016.01.011 · Cited by 463 · see citing works

The Striatum Organizes 3D Behavior via Moment-to-Moment Action Selection

Markowitz, J. E., Gillis, W. F., Beron, C. C., Neufeld, S. Q., Robertson, K., Bhagat, N. D., Peterson, R. E., Peterson, E., Hyun, M., Linderman, S. W., et al. (2018) · Cell · doi:10.1016/j.cell.2018.04.019 · Cited by 422 · see citing works

Revisiting the Role of Infralimbic Cortex in Fear Extinction with Optogenetics

Do-Monte, F. H., Manzano-Nieves, G., Quiñones-Laracuente, K., Ramos-Medina, L., & Quirk, G. J. (2015) · The Journal of Neuroscience · doi:10.1523/jneurosci.3137-14.2015 · Cited by 385 · see citing works

Selective information routing by ventral hippocampal CA1 projection neurons

Ciocchi, S., Passecker, J., Malagon‐Vina, H., Mikuš, N., & Klausberger, T. (2015) · Science · doi:10.1126/science.aaa3245 · Cited by 344 · see citing works

Control of Stress-Induced Persistent Anxiety by an Extra-Amygdala Septohypothalamic Circuit

Anthony, T. E., Dee, N., Bernard, A., Lerchner, W., Heintz, N., & Anderson, D. J. (2014) · Cell · doi:10.1016/j.cell.2013.12.040 · Cited by 310 · see citing works

Single Units in the Medial Prefrontal Cortex with Anxiety-Related Firing Patterns Are Preferentially Influenced by Ventral Hippocampal Activity

Adhikari, A., Topiwala, M. A., & Gordon, J. A. (2011) · Neuron · doi:10.1016/j.neuron.2011.07.027 · Cited by 285 · see citing works

Opening Holes in the Blanket of Inhibition: Localized Lateral Disinhibition by VIP Interneurons

Karnani, M. M., Jackson, J., Ayzenshtat, I., Hamzehei Sichani, A., Manoocheri, K., Kim, S., & Yuste, R. (2016) · The Journal of Neuroscience · doi:10.1523/jneurosci.3646-15.2016 · Cited by 236 · see citing works

Delay activity of specific prefrontal interneuron subtypes modulates memory-guided behavior

Kamigaki, T., & Dan, Y. (2017) · Nature Neuroscience · doi:10.1038/nn.4554 · Cited by 208 · see citing works

Dynamic, Cell-Type-Specific Roles for GABAergic Interneurons in a Mouse Model of Optogenetically Inducible Seizures

Khoshkhoo, S., Vogt, D. L., & Sohal, V. S. (2016) · Neuron · doi:10.1016/j.neuron.2016.11.043 · Cited by 154 · see citing works

Developmental Dysfunction of VIP Interneurons Impairs Cortical Circuits

Batista-Brito, R., Vinck, M., Ferguson, K. A., Chang, J. T., Laubender, D., Lur, G., Mossner, J. M., Hernandez, V. G., Ramakrishnan, C., Deisseroth, K., et al. (2017) · Neuron · doi:10.1016/j.neuron.2017.07.034 · Cited by 135 · see citing works

Marble burying as a test of the delayed anxiogenic effects of acute immobilisation stress in mice

Kedia, S., & Chattarji, S. (2014) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2014.06.012 · Cited by 101 · see citing works

An inhibitory pull–push circuit in frontal cortex

García‐Junco‐Clemente, P., Ikrar, T., Tring, E., Xu, X., Ringach, D. L., & Trachtenberg, J. T. (2017) · Nature Neuroscience · doi:10.1038/nn.4483 · Cited by 84 · see citing works

Patterns of Theta Activity in Limbic Anxiety Circuit Preceding Exploratory Behavior in Approach-Avoidance Conflict

Jacinto, L., Cerqueira, J., & Sousa, N. (2016) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2016.00171 · Cited by 61 · see citing works

Serotonin 1B Receptors Regulate Prefrontal Function by Gating Callosal and Hippocampal Inputs

Kjærby, C., Athilingam, J. C., Robinson, S. E., Iafrati, J., & Sohal, V. S. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.11.036 · Cited by 54 · see citing works

Cortical Control of Spatial Resolution by VIP⁺Interneurons

Ayzenshtat, I., Karnani, M. M., Jackson, J., & Yuste, R. (2016) · The Journal of Neuroscience · doi:10.1523/jneurosci.1920-16.2016 · Cited by 50 · see citing works

Inhibitory coupling specifically generates emergent gamma oscillations in diverse cell types

Sohal, V. S., & Huguenard, J. R. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0509291102 · Cited by 40 · see citing works

Putative Microcircuit-Level Substrates for Attention Are Disrupted in Mouse Models of Autism

Luongo, F. J., Horn, M. E., & Sohal, V. S. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.04.014 · Cited by 27 · see citing works

Correlations between prefrontal neurons form a small-world network that optimizes the generation of multineuron sequences of activity

Luongo, F. J., Zimmerman, C. A., Horn, M. E., & Sohal, V. S. (2016) · Journal of Neurophysiology · doi:10.1152/jn.01043.2015 · Cited by 11 · see citing works

Circuit organization of the rodent medial prefrontal cortex

Anastasiades, P. G., & Carter, A. G. (2021) · Trends in Neurosciences · doi:10.1016/j.tins.2021.03.006 · Cited by 314 · see citing works

Mechanisms of synaptic transmission dysregulation in the prefrontal cortex: pathophysiological implications

Yan, Z., & Rein, B. (2022) · Molecular Psychiatry · doi:10.1038/s41380-021-01092-3 · Cited by 300 · see citing works

The mouse prefrontal cortex: Unity in diversity

Le Merre, P., Ährlund-Richter, S., & Carlén, M. (2021) · Neuron · doi:10.1016/j.neuron.2021.03.035 · Cited by 207 · see citing works

Hippocampus: Molecular, Cellular, and Circuit Features in Anxiety

Shi, H., Wang, S., Wang, X., Zhang, R.-X., & Zhu, L. (2023) · Neuroscience Bulletin · doi:10.1007/s12264-023-01020-1 · Cited by 151 · see citing works

Top-down control of hippocampal signal-to-noise by prefrontal long-range inhibition

Malik, R., Li, Y., Schamiloglu, S., & Sohal, V. S. (2022) · Cell · doi:10.1016/j.cell.2022.04.001 · Cited by 138 · see citing works

Hippocampal-Prefrontal Theta Transmission Regulates Avoidance Behavior

Padilla-Coreano, N., Canetta, S., Mikofsky, R. M., Alway, E., Passecker, J., Myroshnychenko, M., Garcia‐García, Á. L., Warren, R., Teboul, E., Blackman, D. R., et al. (2019) · Neuron · doi:10.1016/j.neuron.2019.08.006 · Cited by 134 · see citing works

Dynamics of a disinhibitory prefrontal microcircuit in controlling social competition

Zhang, C., Zhu, H. L., Ni, Z., Xin, Q., Zhou, T., Wu, R., Gao, G., Gao, Z., Ma, H., Li, H., et al. (2021) · Neuron · doi:10.1016/j.neuron.2021.10.034 · Cited by 123 · see citing works

Ventral Hippocampal-Prefrontal Interaction Affects Social Behavior via Parvalbumin Positive Neurons in the Medial Prefrontal Cortex

Sun, Q., Li, X., Li, A., Zhang, J., Ding, Z., Gong, H., & Luo, Q. (2020) · iScience · doi:10.1016/j.isci.2020.100894 · Cited by 105 · see citing works

Prefrontal Cortex Corticotropin-Releasing Factor Neurons Control Behavioral Style Selection under Challenging Situations

Chen, P., Lou, S., Huang, Z., Wang, Z., Shan, Q., Wang, Y., Yang, Y., Li, X., Gong, H., Jin, Y., et al. (2020) · Neuron · doi:10.1016/j.neuron.2020.01.033 · Cited by 97 · see citing works

Cortical disinhibitory circuits: cell types, connectivity and function

Kullander, K., & Topolnik, L. (2021) · Trends in Neurosciences · doi:10.1016/j.tins.2021.04.009 · Cited by 83 · see citing works

Two opposing hippocampus to prefrontal cortex pathways for the control of approach and avoidance behaviour

Sánchez-Bellot, C., AlSubaie, R., Mishchanchuk, K., Wee, R. W. S., & MacAskill, A. F. (2022) · Nature Communications · doi:10.1038/s41467-022-27977-7 · Cited by 73 · see citing works

Cell-type-specific recruitment of GABAergic interneurons in the primary somatosensory cortex by long-range inputs

Naskar, S., Qi, J., Pereira, F., Gerfen, C. R., & Lee, S. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.108774 · Cited by 72 · see citing works

Common Principles in Functional Organization of VIP/Calretinin Cell-Driven Disinhibitory Circuits Across Cortical Areas

Guet-McCreight, A., Skinner, F. K., & Topolnik, L. (2020) · Frontiers in Neural Circuits · doi:10.3389/fncir.2020.00032 · Cited by 64 · see citing works

Elevation of hilar mossy cell activity suppresses hippocampal excitability and avoidance behavior

Wang, K., Wu, J., Cheng, J., Chen, C.-C., Wong, W.-Y., Averkin, R. G., Tamás, G., Nakazawa, K., & Lien, C. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109702 · Cited by 51 · see citing works

Circuit-Based Biomarkers for Mood and Anxiety Disorders

Xia, F., & Kheirbek, M. A. (2020) · Trends in Neurosciences · doi:10.1016/j.tins.2020.08.004 · Cited by 53 · see citing works

Transforming Discoveries About Cortical Microcircuits and Gamma Oscillations Into New Treatments for Cognitive Deficits in Schizophrenia

Sohal, V. S. (2022) · American Journal of Psychiatry · doi:10.1176/appi.ajp.20220147 · Cited by 49 · see citing works

Neuropeptide System Regulation of Prefrontal Cortex Circuitry: Implications for Neuropsychiatric Disorders

Casello, S. M., Flores, R. J., Yarur, H. E., Wang, H., Awanyai, M., Arenivar, M. A., Jaime-Lara, R. B., Bravo-Rivera, H., & Tejeda, H. A. (2022) · Frontiers in Neural Circuits · doi:10.3389/fncir.2022.796443 · Cited by 48 · see citing works

Enkephalin release from VIP interneurons in the hippocampal CA2/3a region mediates heterosynaptic plasticity and social memory

Leroy, F., de Solis, C. A., Boyle, L. M., Bock, T., Lofaro, O. M., Buss, E. W., Asok, A., Kandel, E. R., & Siegelbaum, S. A. (2021) · Molecular Psychiatry · doi:10.1038/s41380-021-01124-y · Cited by 48 · see citing works

Anxiety-related activity of ventral hippocampal interneurons

Forro, T., Volitaki, E., Malagon‐Vina, H., Klausberger, T., Nevian, T., & Ciocchi, S. (2022) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2022.102368 · Cited by 46 · see citing works

VIP-Expressing GABAergic Neurons: Disinhibitory vs. Inhibitory Motif and Its Role in Communication Across Neocortical Areas

Apicella, A. J., & Marchionni, I. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.811484 · Cited by 43 · see citing works

Somatostatin peptide signaling dampens cortical circuits and promotes exploratory behavior

Brockway, D. F., Griffith, K. R., Aloimonos, C. M., Clarity, T. T., Moyer, J. B., Smith, G. C., Dao, N. C., Hossain, M. S., Drew, P. J., Gordon, J. A., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112976 · Cited by 42 · see citing works

Circuit mechanism for suppression of frontal cortical ignition during NREM sleep

Li, B., Ma, C., Huang, Y., Ding, X., Silverman, D., Chen, C., Darmohray, D. M., Lu, L., Liu, S., Montaldo, G., et al. (2023) · Cell · doi:10.1016/j.cell.2023.11.012 · Cited by 42 · see citing works

Amygdala-hippocampus somatostatin interneuron beta-synchrony underlies a cross-species biomarker of emotional state

Jackson, A. D., Cohen, J. L., Phensy, A. J., Chang, E. F., Dawes, H. E., & Sohal, V. S. (2024) · Neuron · doi:10.1016/j.neuron.2023.12.017 · Cited by 39 · see citing works

VIP-expressing interneurons in the anterior insular cortex contribute to sensory processing to regulate adaptive behavior

Ramos-Prats, A., Paradiso, E., Castaldi, F., Sadeghi, M., Mir, M. Y., Hörtnagl, H., Göbel, G., & Ferraguti, F. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110893 · Cited by 37 · see citing works

Altered hippocampal-prefrontal communication during anxiety-related avoidance in mice deficient for the autism-associated gene Pogz

Cunniff, M. M., Markenscoff-Papadimitriou, E., Ostrowski, J., Rubenstein, J. L. R., & Sohal, V. S. (2020) · eLife · doi:10.7554/elife.54835 · Cited by 35 · see citing works

ACh signaling modulates activity of the GABAergic signaling network in the basolateral amygdala and behavior in stress-relevant paradigms

Mineur, Y. S., Mose, T. N., Maibom, K. L., Pittenger, S. T., Soares, A. R., Wu, H., Taylor, S. R., Huang, Y., & Picciotto, M. R. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01749-7 · Cited by 36 · see citing works

The hippocampus associated GABAergic neural network impairment in early-stage of Alzheimer's disease

Tang, Y., Yan, Y., Mao, J., Ni, J., & Qing, H. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.101865 · Cited by 34 · see citing works

A Role for Vasoactive Intestinal Peptide Interneurons in Neurodevelopmental Disorders

Goff, K. M., & Goldberg, E. M. (2021) · Developmental Neuroscience · doi:10.1159/000515264 · Cited by 34 · see citing works

Disinhibition by VIP interneurons is orthogonal to cross-modal attentional modulation in primary visual cortex

Myers-Joseph, D., Wilmes, K. A., Fernández-Otero, M., Claudia Clopath, A., & Khan, A. G. (2023) · Neuron · doi:10.1016/j.neuron.2023.11.006 · Cited by 31 · see citing works

Cholecystokinin-Mediated Neuromodulation of Anxiety and Schizophrenia: A “Dimmer-Switch” Hypothesis

Ballaz, S., & Bourin, M. (2020) · Current Neuropharmacology · doi:10.2174/1570159x18666201113145143 · Cited by 29 · see citing works

Prefrontal Interneurons: Populations, Pathways, and Plasticity Supporting Typical and Disordered Cognition in Rodent Models

Kupferschmidt, D. A., Cummings, K. A., Joffe, M. E., MacAskill, A. F., Malik, R., Sánchez-Bellot, C., Tejeda, H. A., & Yarur, H. E. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.1136-22.2022 · Cited by 29 · see citing works

Activation of VIP interneurons in the prefrontal cortex ameliorates neuropathic pain aversiveness

Li, M., Zhou, H., Teng, S., & Yang, G. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.111333 · Cited by 28 · see citing works

Characterization of exploratory patterns and hippocampal–prefrontal network oscillations during the emergence of free exploration

Dong, W.-X., Chen, H., Sit, T. P. H., Han, Y., Song, F., Vyssotski, A. L., Gross, C. T., Si, B., & Zhan, Y. (2021) · 中国科学通报：英文版 · doi:10.1016/j.scib.2021.05.018 · Cited by 27 · see citing works

Mediodorsal thalamus projection to medial prefrontal cortical mediates social defeat stress-induced depression-like behaviors

Li, F., Zheng, X., Wang, H., Meng, L., Chen, M., Hui, Y., Liu, D., Li, Y., Xie, K., Zhang, J., et al. (2024) · Neuropsychopharmacology · doi:10.1038/s41386-024-01829-y · Cited by 24 · see citing works

Under or Absent Reporting of Light Stimuli in Testing of Anxiety-Like Behaviors in Rodents: The Need for Standardization

Neuwirth, L. S., Verrengia, M. T., Harikinish-Murrary, Z. I., Orens, J. E., & Lopez, O. E. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.912146 · Cited by 24 · see citing works

Prefrontal Regulation of Social Behavior and Related Deficits: Insights From Rodent Studies

Mack, N. R., Bouras, N. N., & Gao, W. (2024) · Biological Psychiatry · doi:10.1016/j.biopsych.2024.03.008 · Cited by 24 · see citing works

Alternative splicing at neuroligin site A regulates glycan interaction and synaptogenic activity

Oku, S., Feng, H., Connor, S. A., Toledo, A., Zhang, P., Zhang, Y., Thoumine, O. R., Zhang, C., & Craig, A. M. (2020) · eLife · doi:10.7554/elife.58668 · Cited by 20 · see citing works

Acute alcohol and chronic drinking bidirectionally regulate the excitability of prefrontal cortex vasoactive intestinal peptide interneurons

Thompson, S. M., Fabian, C. B., Ferranti, A. S., & Joffe, M. E. (2023) · Neuropharmacology · doi:10.1016/j.neuropharm.2023.109638 · Cited by 19 · see citing works

Differential Synaptic Dynamics and Circuit Connectivity of Hippocampal and Thalamic Inputs to the Prefrontal Cortex

Canetta, S., Teboul, E., Holt, E. S., Bolkan, S. S., Padilla-Coreano, N., Gordon, J. A., Harrison, N. L., & Kellendonk, C. (2020) · Cerebral Cortex Communications · doi:10.1093/texcom/tgaa084 · Cited by 16 · see citing works

Blockade of corticotropin-releasing factor-1 receptors in the infralimbic cortex prevents stress-induced reinstatement of alcohol seeking in male Wistar rats: Evidence of interaction between CRF1 and orexin receptor signaling

Flores‐Ramirez, F. J., Matzeu, A., Sánchez‐Marín, L., & Martin‐Fardon, R. (2022) · Neuropharmacology · doi:10.1016/j.neuropharm.2022.109046 · Cited by 17 · see citing works

Identification of Vulnerable Interneuron Subtypes in 15q13.3 Microdeletion Syndrome Using Single-Cell Transcriptomics

Malwade, S., Gasthaus, J., Bellardita, C., Andelic, M., Moric, B., Korshunova, I., Kiehn, O., Vasistha, N. A., & Khodosevich, K. (2021) · Biological Psychiatry · doi:10.1016/j.biopsych.2021.09.012 · Cited by 17 · see citing works

Inhibitory and disinhibitory VIP IN-mediated circuits in neocortexPreprint

Dellal, S. S., Zurita, H., Kruglikov, I., Valero, M., Abad-Perez, P., Geron, E., Meng, J. H., Prönneke, A., Hanson, J. L., Mir, E., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.02.26.640383 · Cited by 23 · see citing works

Divergent neurocircuitry dissociates two components of the stress response: glucose mobilization and anxiety-like behavior

Jia, X., Chen, S., Li, X., Tao, S., Lai, J., Liu, H., Huang, K., Tian, Y., Wei, P., Yang, F., et al. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.111586 · Cited by 14 · see citing works

Interacting rhythms enhance sensitivity of target detection in a fronto-parietal computational model of visual attention

Aussel, A., Fiebelkorn, I. C., Kästner, S., Kopell, N., & Pittman-Polletta, B. (2023) · eLife · doi:10.7554/elife.67684 · Cited by 16 · see citing works

Fluorescence microendoscopy for in vivo deep-brain imaging of neuronal circuits

Laing, B. T., Siemian, J. N., Sarsfield, S., & Aponte, Y. (2020) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2020.109015 · Cited by 15 · see citing works

Prefrontal Cortical Control of Anxiety: Recent Advances

Mack, N. R., Deng, S., Yang, S.-S., Shu, Y., & Gao, W. (2022) · The Neuroscientist · doi:10.1177/10738584211069071 · Cited by 14 · see citing works

Developmental Disruption of Mef2c in Medial Ganglionic Eminence–Derived Cortical Inhibitory Interneurons Impairs Cellular and Circuit Function

Ward, C., Nasrallah, K., Tran, D., Sabri, E., Vazquez, A., Sjulson, L., Castillo, P. E., & Batista‐Brito, R. (2024) · Biological Psychiatry · doi:10.1016/j.biopsych.2024.05.021 · Cited by 14 · see citing works

Convergence of Clinically Relevant Manipulations on Dopamine-Regulated Prefrontal Activity Underlying Stress Coping Responses

Wilke, S. A., Lavi, K., Byeon, S., Donohue, K. C., & Sohal, V. S. (2021) · Biological Psychiatry · doi:10.1016/j.biopsych.2021.11.008 · Cited by 14 · see citing works

Highly unstable heterogeneous representations in VIP interneurons of the anterior cingulate cortex

Johnson, C., Kretsge, L. N., Yen, W., Sriram, B., O’Connor, A., Liu, R. S., Jimenez, J., Phadke, R. A., Wingfield, K. K., Yeung, C., et al. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01485-y · Cited by 13 · see citing works

Update on neurobiological mechanisms of fear: illuminating the direction of mechanism exploration and treatment development of trauma and fear-related disorders

Li, Y., Zhi, W.-J., Qi, B., Wang, L.-F., & Hu, X. (2023) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2023.1216524 · Cited by 10 · see citing works

The role of mPFC and MTL neurons in human choice under goal-conflict

Gazit, T., Gonen, T., Gurevitch, G., Cohen, N., Strauss, I., Zeevi, Y., Yamin, H. G., Fahoum, F., Hendler, T., & Fried, I. (2020) · Nature Communications · doi:10.1038/s41467-020-16908-z · Cited by 10 · see citing works

Overexpression of the schizophrenia risk gene C4 in PV cells drives sex-dependent behavioral deficits and circuit dysfunction

Fournier, L. A., Phadke, R. A., Salgado, M., Brack, A., Nocon, J. C., Bolshakova, S., Grant, J. R., Padró-Luna, N. M., Sen, K., & Cruz‐Martín, A. (2024) · iScience · doi:10.1016/j.isci.2024.110800 · Cited by 9 · see citing works

Neuronal identity and cognitive control dynamics in the PFC

Nakajima, M. (2021) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2021.08.014 · Cited by 8 · see citing works

Dysfunction of the Hippocampal-Lateral Septal Circuit Impairs Risk Assessment in Epileptic Mice

Cao, Y. H., Sun, C., Huang, J., Sun, P., Wang, L., He, S., Liao, J., Lu, Z., Lu, Y., & Zhong, C. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.828891 · Cited by 8 · see citing works

Maturation of hippocampus-medial prefrontal cortex projections defines a pathway-specific sensitive period for cognitive flexibility

Cruz-Sanchez, A., LaDouceur, K. E., Abdusalom, A., Chasiotis, H., Gugustea, R., Inayat, M., Mumtaz, U., Hasantash, M., Anacker, C., & Arruda-Carvalho, M. (2026) · Cell Reports · doi:10.1016/j.celrep.2025.116812 · Cited by 9 · see citing works

Loss of GABA co-transmission from cholinergic neurons impairs behaviors related to hippocampal, striatal, and medial prefrontal cortex functions

Goral, R. O., Harper, K. M., Bernstein, B. J., Fry, S. A., Lamb, P. W., Moy, S. S., Cushman, J. D., & Yakel, J. L. (2022) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2022.1067409 · Cited by 7 · see citing works

Layer-specific input to medial prefrontal cortex is linked to stress susceptibility

Solakoğlu, S. T., Erdener, Ş. E., Gliko, O., Can, A., Sümbül, U., & Eren-Koçak, E. (2025) · Translational Psychiatry · doi:10.1038/s41398-025-03258-x · Cited by 5 · see citing works

Thienopyrimidinone Derivatives as a GluN2B/C/D Biased, Positive Allosteric Modulator of the N-Methyl- d -Aspartate Receptor

Fritzemeier, R. G., Akins, N. S., Arcoria, P. J., Paladugu, S., Ullman, E. Z., Allen, J. P., Sheikh, R., Nocilla, K. A., McDaniels, E. D., Coleman, E. M., et al. (2025) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.4c02912 · Cited by 5 · see citing works

Context-invariant socioemotional encoding by prefrontal ensembles

Frost, N. A., Donohue, K. C., Kwak, D., & Sohal, V. S. (2025) · Nature Communications · doi:10.1038/s41467-025-59575-8 · Cited by 5 · see citing works

Executive dysfunction is associated with altered hippocampal-prefrontal functional connectivity in 3xTg Alzheimer’s model mice

Cunliffe, G., Tan, L. Y., Jung, S., Turner, J., & Gigg, J. (2025) · Communications Biology · doi:10.1038/s42003-025-08546-2 · Cited by 4 · see citing works

Synaptic configuration and reconfiguration in the neocortex are spatiotemporally selective

Sohn, J. (2023) · Anatomical Science International · doi:10.1007/s12565-023-00743-5 · Cited by 4 · see citing works

Exploring Cortical Interneurons in Substance Use Disorder: From Mechanisms to Therapeutic Perspectives

Shi, S., Chen, T., Su, H., & Zhao, M. (2025) · The Neuroscientist · doi:10.1177/10738584241310156 · Cited by 4 · see citing works

Pathway Matters: Prefrontal Control of Negative Emotions via Distinct Downstream Regions

Zheng, J., Liu, N., & Xu, H. (2021) · Neuroscience Bulletin · doi:10.1007/s12264-021-00793-7 · Cited by 4 · see citing works

Rare mutations implicate CGE interneurons as a vulnerable axis of cognitive deficits across psychiatric disordersPreprint

Herrlinger, S. A., Wang, J., Rao, B. Y., Rodriguez, E., Chang, J., Gogos, J., Losonczy, A., & Vitkup, D. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.03.28.645799 · Cited by 6 · see citing works

Synaptic plasticity of prefrontal long-range inhibition regulates cognitive flexibility

Zhu, X., Hagopian, L. L., Wallquist, K. E., & Sohal, V. S. (2026) · Neuron · doi:10.1016/j.neuron.2026.04.028 · Cited by 3 · see citing works

Inhibition of SERT and NMDAR synergistically confers rapid antidepressant effects of ketamine

Luo, H., Chen, M., Ning, Y., Ren, L., Lu, Y., Sun, J., Zhu, X., Ran, M., Guo, J., Lu, C., et al. (2025) · National Science Review · doi:10.1093/nsr/nwaf367 · Cited by 3 · see citing works

Prefrontal cortex interneurons and their contributions to attention, working memory, and adaptive behavior

Boroujeni, K. B., Balaram, P., Tiesinga, P. H. E., & Womelsdorf, T. (2025) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2025.102873 · Cited by 4 · see citing works

Reliable Inference of the Encoding of Task States by Individual Neurons Using Calcium Imaging

Huang, H. Z., Shah, G., Adwanikar, H., & Mysore, S. P. (2026) · eNeuro · doi:10.1523/eneuro.0378-25.2025 · Cited by 3 · see citing works

Cell-type specific reductions in interneuron gene expression within the cingulate gyrus of schizophrenia and bipolar disorder subjects

Krolewski, D. M., Khalil, H., Waselus, M., Vawter, M. P., Bunney, B. G., Myers, R., Lee, F. S., Schatzberg, A. F., Bunney, W. E., Akil, H., et al. (2025) · Schizophrenia · doi:10.1038/s41537-025-00638-6 · Cited by 3 · see citing works

Shaping long-range functional connectivity through prefrontal interneuron plasticity

Kupferschmidt, D. A., & Gordon, J. A. (2022) · Neuropsychopharmacology · doi:10.1038/s41386-022-01395-1 · Cited by 3 · see citing works

Perspective: Hippocampal theta rhythm as a potential vestibuloacoustic biomarker of anxiety

Bosecke, C., Ng, M., Dastgheib, Z. A., & Lithgow, B. J. (2024) · European Journal of Neuroscience · doi:10.1111/ejn.16641 · Cited by 3 · see citing works

An electrical brain network encodes anxiety in health and depressive statesPreprint

Hughes, D. N., Klein, M. H., Walder-Christensen, K. K., Thomas, G. E., Grossman, Y. S., Waters, D., Matthews, A. E., Carson, W. E., Filali, Y., Tsyglakova, M., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.06.26.600900 · Cited by 3 · see citing works

Pre-trauma cognitive traits predict fear generalization and associated prefrontal functioning in a longitudinal rodent model

Szente, L., Aliczki, M., Balla, G. Y., Maróthy, R. D., Varga, Z. K., Varga, B. Á., Borhegyi, Z., Bíró, L., Demeter, K., Miskolczi, C., et al. (2025) · Neuropsychopharmacology · doi:10.1038/s41386-025-02263-4 · Cited by 2 · see citing works

Neuropeptidergic systems in psychiatric disorders

Hodzic, S., & Riedemann, T. (2026) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1654292 · Cited by 2 · see citing works

Alcohol Withdrawal Alters the Inhibitory Landscape of the Prelimbic Cortex in an Interneuron- and Sex-specific Manner

Quadir, S. G., Zaidi, S. D., Cone, M. G., & Patel, S. (2025) · Addiction Neuroscience · doi:10.1016/j.addicn.2025.100237 · Cited by 3 · see citing works

Amygdalar Excitation of Hippocampal Interneurons Can Lead to Emotion-driven Overgeneralization of Context

John, Y. J., Wang, J., Bullock, D. H., & Barbas, H. (2024) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_02109 · Cited by 7 · see citing works

Medial Entorhinal VIP-expressing interneurons receive direct input from Anterior Dorsal Thalamus and are critical for spatial memoryPreprint

Oulé, M., Badrinarayanan, S., Sundar-Maccagno, R., & Brandon, M. P. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.08.26.609578 · Cited by 2 · see citing works

Gene expression differences in the olfactory bulb associated with differential social interactions and olfactory deficits in Pax6 heterozygous mice

Daems, C., Baz, E., D’Hooge, R., Callaerts‐Vegh, Z., & Callaerts, P. (2025) · Biology Open · doi:10.1242/bio.061647 · Cited by 1 · see citing works

Medial entorhinal VIP-expressing interneurons receive input from the thalamic anterior dorsal nucleus and are critical for spatial memory

Oulé, M., Badrinarayanan, S., Sundar-Maccagno, R., & Brandon, M. P. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2425024122 · Cited by 1 · see citing works

Integrating anxiety and motivation: Prefrontal mechanisms arbitrating the approach-avoidance conflict

Benson, A. A., & Gao, W. (2026) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2026.106762 · Cited by 1 · see citing works

Loss of the autism associated gene Tbr1 disrupts prediction and encoding by prefrontal ensembles during socioemotional behaviorsPreprint

Turner, M., Schwartz, S. R., Darbandi, S. F., Rubenstein, J. L. R., & Sohal, V. S. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.01.21.633988 · Cited by 1 · see citing works

Activity-induced weakening of hippocampal input to prefrontal VIP interneurons reshapes inhibitory microcircuit function: implications for spatial working memory task acquisitionPreprint

Silverstein, S. E., Clarity, T. T., Deshpande, M. S., Vaughan, E., Novik, S., Yarur, H. E., Zhang, S., Tsai, V. S., Ye, R., Mikofsky, R. M., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.07.21.665987 · Cited by 1 · see citing works

Hyperexcitability of female serotonin neurons underlies sex-specific anxiety responsesPreprint

Pizzoccaro, L., van der Veldt, S., Henderson, F., Simard, A.-S., Perreault, F., Fortin‐Houde, J., Lalot, E., Ducharme, G., & Amilhon, B. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.08.17.670715 · Cited by 3 · see citing works

Genetic Dissection of Neuropeptide Circuits Mediating Psychosocial Stress

Ben-Efraim, Y. J., & Chen, A. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-813156-5.00001-7

Thalamic and medial prefrontal cortical circuits mediate social defeat stress-induced depression-like behaviorsPreprint

Li, F., Wang, H., Meng, L., Chen, M., Zheng, X., Hui, Y., Liu, D., Li, Y., Xie, K., Zhang, J., et al. (2022) · Research Square · doi:10.21203/rs.3.rs-1434398/v1

Some Basic Science and Functional Illness

Blakley, B. W., & Bosecke, C. (2023) · Springer eBooks · doi:10.1007/978-3-031-12998-8_2

Reconstruction of our research protocol for understanding of neuro-behavior relationships: technical advances in spatio-temporal resolution of analysis

Arakawa, H., & Arakawa, K. (2023) · Japanese Journal of Animal Psychology · doi:10.2502/janip.73.2.1

Cell-Type Specific Reductions in Interneuron Gene Expression within Subregions of the Anterior and Posterior Cingulate Gyrus of Schizophrenia and Bipolar Disorder SubjectsPreprint

Krolewski, D. M., Waselus, M., Bunney, B. G., Myers, R., Barchas, J. D., Lee, F. S. Y., Schatzberg, A. F., Bunney, W. E., Akil, H., & Watson, S. J. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.03.20.585908

Dissecting the Hippocampal Regulation of Approach‐Avoidance Conflict: Integrative Perspectives From Optogenetics, Stress Response, and Epigenetics

Forastieri, C., Romito, E., Paplekaj, A., Battaglioli, E., & Rusconi, F. (2024) · Hippocampus · doi:10.1002/hipo.23647

Robust characterization of selectivity of individual neurons to distinct task-relevant behavioral states using calcium imagingPreprint

Huang, H. Z., Shah, G., Adwanikar, H., & Mysore, S. P. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.11.30.626195

Co-evolution of PACAP, VIP and Related Peptides and Their Receptors as Neuroendocrine Signalling Dyads in Vertebrates

Zhang, L., Hernández, V. S., & Eiden, L. E. (2025) · Masterclass in neuroendocrinology · doi:10.1007/978-3-031-80209-6_11

Stress-type specific changes of VIP signaling in limbic regions of the rat brain

Ferro, F., Fontebasso, V., Basille, M., Vaudry, D., & Ebner, K. (2025) · Neuroscience Letters · doi:10.1016/j.neulet.2025.138430

CB1 receptor signaling at the cingulate-striatal circuit is anxiogenic

Kelly, T. J., Liu, X., Huang, Y., Hu, Y., Friedman, V., Hillard, C. J., & Liu, Q.-S. (2026) · Nature Communications · doi:10.1038/s41467-026-71574-x

Computational Approach for the Reliable Inference of Task States Encoded by Neurons Using Calcium Imaging

Huang, H., Adwanikar, H., & Mysore, S. P. (2026) · BIO-PROTOCOL · doi:10.21769/bioprotoc.5867

Cortical PV and VIP interneurons similarly influence SST neuron output despite distinct unitary properties

Preuss, F., Möck, M., Witte, M., & Staiger, J. F. (2026) · Communications Biology · doi:10.1038/s42003-026-10418-2

Treadmill exercise relieves cortical interneuron hyperactivation to prevent stress-induced anxiety-like behaviors in male mice

Wang, Y., Dai, Y., Gao, Z., Wei, J., & Zhang, L. (2026) · Communications Biology · doi:10.1038/s42003-026-10453-z

BindingDB Entry 50023604: Thienopyrimidinone Derivatives as a GluN2B/C/D Biased, Positive Allosteric Modulator of the N-Methyl-d-Aspartate Receptor.

BindingDB (2026) · UC San Diego · doi:10.7270/q26t0smb

Vasoactive intestinal peptide-expressing interneurons modulate the effect of behavioral state on cortical activity

Sabri, E., & Batista‐Brito, R. (2024) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2024.1465836 · Cited by 1 · see citing works

Opening Holes in the Blanket of Inhibition: Localized Lateral Disinhibition by VIP Interneurons

Karnani, M. M., Jackson, J., Ayzenshtat, I., Hamzehei Sichani, A., Manoocheri, K., Kim, S., & Yuste, R. (2016) · The Journal of Neuroscience · doi:10.1523/jneurosci.3646-15.2016 · Cited by 236 · see citing works

Delay activity of specific prefrontal interneuron subtypes modulates memory-guided behavior

Kamigaki, T., & Dan, Y. (2017) · Nature Neuroscience · doi:10.1038/nn.4554 · Cited by 208 · see citing works

Cortical interneurons that specialize in disinhibitory control

Pi, H.-J., Hangya, B., Kvitsiani, D., Sanders, J. I., Huang, Z. J., & Kepecs, A. (2013) · Nature · doi:10.1038/nature12676 · Cited by 1,136 · see citing works

Cortical interneurons that specialize in disinhibitory control. Nature

Pi, H.-J., Hangya, B., Kvitsiani, D., S, J. I., Huang, Z. J., & Kepecs, Á. (2013)