High resolution in situ zymography reveals matrix metalloproteinase activity at glutamatergic synapses

How Matrix Metalloproteinases Regulate Cell Behavior

Sternlicht, M. D., & Werb, Z. (2001) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.17.1.463 · Cited by 3,959 · see citing works

S-nitrosylation of matrix metalloproteinases: signaling pathway to neuronal cell death

Gu, Z., Kaul, M., Yan, B., Kridel, S. J., Cui, J., Strongin, A., Smith, J. W., Liddington, R. C., & Lipton, S. A. (2002) · Science · doi:10.1126/science.1073634 · Cited by 950 · see citing works

Metalloproteinases: Mediators of Pathology and Regeneration in the CNS

Yong, V. W. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1807 · Cited by 582 · see citing works

Matrix metalloproteinase-9 is required for hippocampal late-phase long-term potentiation and memory

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A Highly Specific Inhibitor of Matrix Metalloproteinase-9 Rescues Laminin from Proteolysis and Neurons from Apoptosis in Transient Focal Cerebral Ischemia

Gu, Z., Cui, J.-K., Brown, S. M., Fridman, R., Mobashery, S., Strongin, A., & Lipton, S. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.1563-05.2005 · Cited by 412 · see citing works

Matrix Metalloproteinase-9 Undergoes Expression and Activation during Dendritic Remodeling in Adult Hippocampus

Szklarczyk, A., Lapinska, J., Rylski, M., McKay, R. D. G., & Kaczmarek, L. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-03-00920.2002 · Cited by 392 · see citing works

Matrix metalloproteinases and TIMPs

Woessner, J. F., & Nagase, H. (2000) · Medical Entomology and Zoology · Cited by 380 · see citing works

Matrix metalloproteinases in brain development and remodeling: Synaptic functions and targets

Ethell, I. M., & Ethell, D. W. (2007) · Journal of Neuroscience Research · doi:10.1002/jnr.21273 · Cited by 378 · see citing works

Important role of matrix metalloproteinase 9 in epileptogenesis

Wilczynski, G. M., Konopacki, F. A., Wilczek, E., Lasiecka, Z., Gorlewicz, A., Michaluk, P., Wawrzyniak, M., Malinowska, M., Okulski, P., Kolodziej, L. R., et al. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200708213 · Cited by 292 · see citing works

Effects of extracellular matrix‐degrading proteases matrix metalloproteinases 3 and 9 on spatial learning and synaptic plasticity

Meighan, S. E., Meighan, P. C., Choudhury, P., Davis, C. J., Olson, M. L., Zornes, P. A., Wright, J. W., & Harding, J. W. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2005.03565.x · Cited by 285 · see citing works

Evaluation of Non-Formalin Tissue Fixation for Molecular Profiling Studies

Gillespie, J. W., Best, C. J. M., Bichsel, V. E., et al. (2002) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)64864-x · Cited by 285 · see citing works

Matrix Metalloproteinase-9/Gelatinase B Is Required for Process Outgrowth by Oligodendrocytes

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Matrix metalloproteinase‐2 (MMP‐2) is present in the nucleus of cardiac myocytes and is capable of cleaving poly (ADP‐ribose) polymerase (PARP) in vitro

Kwan, J., Schulze, C. J., Wang, W., León, H., Sarıahmetoğlu, M., Sung, M. M. Y., Sawicka, J., Sims, D., Sawicki, G., & Schulz, R. (2004) · The FASEB Journal · doi:10.1096/fj.02-1202fje · Cited by 258 · see citing works

Matrix metalloproteinases and their endogenous inhibitors in neuronal physiology of the adult brain

Dzwonek, J., Rylski, M., & Kaczmarek, L. (2004) · FEBS Letters · doi:10.1016/j.febslet.2004.03.070 · Cited by 256 · see citing works

Role of Matrix Metalloproteinases in Delayed Neuronal Damage after Transient Global Cerebral Ischemia

Lee, S., Tsuji, K., Lee, S.-R., & Lo, E. H. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.4243-03.2004 · Cited by 241 · see citing works

Microglial Activation and Matrix Protease Generation During Focal Cerebral Ischemia

del Zoppo, G. J., Milner, R., Mabuchi, T., Hung, S. Y., Wang, X., Berg, G. I., & Koziol, J. A. (2007) · Stroke · doi:10.1161/01.str.0000254477.34231.cb · Cited by 234 · see citing works

Matrix metalloproteases and their inhibitors are produced by overlapping populations of activated astrocytes

Muir, E. M., Adcock, K. H., Morgenstern, D. A., Clayton, R., von Stillfried, N., Rhodes, K., Ellis, C., Fawcett, J. W., & Rogers, J. H. (2002) · Molecular Brain Research · doi:10.1016/s0169-328x(02)00132-8 · Cited by 206 · see citing works

β-Dystroglycan as a Target for MMP-9, in Response to Enhanced Neuronal Activity

Michaluk, P., Kolodziej, L. R., Mioduszewska, B., Wilczynski, G. M., Dzwonek, J., Jaworski, J., Górecki, D. C., Ottersen, O. P., & Kaczmarek, L. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m700641200 · Cited by 189 · see citing works

In vivo roles for matrix metalloproteinase-9 in mature hippocampal synaptic physiology and plasticity

Bozdagi, O., Nagy, V., Kwei, K. T., & Huntley, G. W. (2007) · Journal of Neurophysiology · doi:10.1152/jn.00202.2007 · Cited by 182 · see citing works

Neuronal activity‐dependent increase of net matrix metalloproteinase activity is associated with MMP‐9 neurotoxicity after kainate

Jourquin, J., Tremblay, E., Décanis, N., Charton, G., Hanessian, S., Chollet, A., Le Diguardher, T., Khrestchatisky, M., & Rivera, S. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02876.x · Cited by 178 · see citing works

Activation of NMDA receptors promotes dendritic spine development through MMP-mediated ICAM-5 cleavage

Tian, L., Stefanidakis, M., Lin, N., Lint, P. V., Nyman-Huttunen, H., Libert, C., Itohara, S., Mishina, M., Rauvala, H., & Gahmberg, C. G. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200612097 · Cited by 173 · see citing works

Low Molecular Weight Inhibitors in Corneal Ulcerationa

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TIMP-1 Abolishes MMP-9-Dependent Long-lasting Long-term Potentiation in the Prefrontal Cortex

Okulski, P., Jay, T. M., Jaworski, J., Duniec, K., Dzwonek, J., Konopacki, F. A., Wilczynski, G. M., Sánchez‐Capelo, A., Mallet, J. J., & Kaczmarek, L. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.09.012 · Cited by 154 · see citing works

Matrix metalloproteinase‐2 (MMP‐2) regulates astrocyte motility in connection with the actin cytoskeleton and integrins

Ogier, C., Bernard, A., Chollet-Gravey, A.-M., Diguardher, T. L., Hanessian, S., Charton, G., Khrestchatisky, M., & Rivera, S. (2006) · Glia · doi:10.1002/glia.20349 · Cited by 124 · see citing works

Metabolic Mapping of Proteinase Activity with Emphasis on In Situ Zymography of Gelatinases

Frederiks, W. M., & Mook, O. R. F. (2004) · Journal of Histochemistry & Cytochemistry · doi:10.1369/jhc.4r6251.2004 · Cited by 120 · see citing works

Matrix metalloproteases: degradation of the inhibitory environment of the transected optic nerve and the scar by regenerating axons

Ahmed, Z., Dent, R. G., Leadbeater, W. E., Smith, C., Berry, M., & Logan, A. (2004) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2004.08.013 · Cited by 102 · see citing works

Matrix metalloproteinase-9 in glutamate-dependent adult brain function and dysfunction

Michaluk, P., & Kaczmarek, L. (2007) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4402141 · Cited by 100 · see citing works

Synaptic localization of seizure-induced matrix metalloproteinase-9 mRNA

Konopacki, F. A., Rylski, M., Wilczek, E., Amborska, R., Detka, D., Kaczmarek, L., & Wilczynski, G. M. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.08.026 · Cited by 81 · see citing works

The matrix metalloproteinases and CNS plasticity: An overview

Milward, E. A., Fitzsimmons, C., Szklarczyk, A., & Conant, K. E. (2007) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2007.04.010 · Cited by 63 · see citing works

The discovery of anthranilic acid-based MMP inhibitors. Part 1: SAR of the 3-position

Levin, J. I., Du, M. T., DiJoseph, J. F., Killar, L. M., Sung, A., Walter, T., Sharr, M. A., Roth, C. E., Moy, F. J., Powers, R., et al. (2001) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/s0960-894x(00)00642-9 · Cited by 45 · see citing works

Regional and age-related expression of gelatinases in the brains of young and old rats after treatment with kainic acid

Zhang, J. W., Deb, S., & Gottschall, P. E. (2000) · Neuroscience Letters · doi:10.1016/s0304-3940(00)01582-2 · Cited by 42 · see citing works

Serine proteases regulating synaptic plasticity

Shiosaka, S. (2004) · Anatomical Science International · doi:10.1111/j.1447-073x.2004.00080.x · Cited by 29 · see citing works

The dual role of the extracellular matrix in synaptic plasticity and homeostasis

Dityatev, A., Schachner, M., & Sonderegger, P. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2898 · Cited by 559 · see citing works

Very long-term memories may be stored in the pattern of holes in the perineuronal net

Tsien, R. Y. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1310158110 · Cited by 244 · see citing works

A delicate balance: role of MMP-9 in brain development and pathophysiology of neurodevelopmental disorders.

Reinhard, S. M., Razak, K., & Ethell, I. M. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00280 · Cited by 219 · see citing works

MMPs in learning and memory and neuropsychiatric disorders

Beroun, A., Mitra, S., Michaluk, P., Pijet, B., Stefaniuk, M., & Kaczmarek, L. (2019) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-019-03180-8 · Cited by 207 · see citing works

Experience-dependent plasticity and modulation of growth regulatory molecules at central synapses

Foscarin, S., Ponchione, D., Pajaj, E., Leto, K., Gawlak, M., Wilczynski, G. M., Rossi, F., & Carulli, D. (2011) · PLoS ONE · doi:10.1371/journal.pone.0016666 · Cited by 128 · see citing works

Light reintroduction after dark exposure reactivates plasticity in adults via perisynaptic activation of MMP-9

Murase, S., Lantz, C. L., & Quinlan, E. M. (2017) · eLife · doi:10.7554/elife.27345 · Cited by 87 · see citing works

ECM in brain aging and dementia

Morawski, M., Filippov, M., Tzinia, A., Tsilibary, E., & Vargova, L. (2014) · Progress in Brain Research · doi:10.1016/b978-0-444-63486-3.00010-4 · Cited by 84 · see citing works

Blocking human fear memory with the matrix metalloproteinase inhibitor doxycycline

Bach, D. R., Tzovara, A., & Vunder, J. (2018) · Molecular Psychiatry · doi:10.1038/mp.2017.65 · Cited by 64 · see citing works

Matrix metalloproteinase-9 activity increased by two different types of epileptic seizures that do not induce neuronal death: A possible role in homeostatic synaptic plasticity

Takács, E., Nyilas, R., Szepesi, Z., Baracskay, P., Karlsen, B., Røsvold, T., Bjørkum, A. A., Czurkó, A., Kovács, Z., Kékesi, A. K., et al. (2010) · Neurochemistry International · doi:10.1016/j.neuint.2010.03.003 · Cited by 63 · see citing works

Inhibition of matrix metalloproteinases prevents the potentiation of nondeprived-eye responses after monocular deprivation in juvenile rats

Spolidoro, M., Putignano, E., Munafò, C., Maffei, L., & Pizzorusso, T. (2012) · Cerebral Cortex · doi:10.1093/cercor/bhr158 · Cited by 58 · see citing works

Zymographical Techniques for Detectionof Matrix Metalloproteinases

Iwai, S., Nakanishi‐Ueda, T., Armstrong, D., et al. (2008) · Methods in molecular biology · doi:10.1007/978-1-60327-517-0_10 · Cited by 7 · see citing works

Analysis of Enzymatic Activity of Matrix Metalloproteinase (MMP) by Collagen Zymography in Melanoma

Walia, V., & Samuels, Y. (2018) · Methods in molecular biology · doi:10.1007/978-1-4939-7595-2_10 · Cited by 5 · see citing works

Imbalance between matrix metalloproteinases and tissue inhibitor of metalloproteinases in hypertensive vascular remodeling

de Castro, M. M., Rizzi, É., Prado, C. M., et al. (2009) · Matrix Biology · doi:10.1016/j.matbio.2009.11.005 · Cited by 117 · see citing works

Detection of Matrix Metalloproteinases by Zymography

Tajhya, R. B., Patel, R. S., & Beeton, C. (2017) · Methods in molecular biology · doi:10.1007/978-1-4939-6863-3_12 · Cited by 61 · see citing works

Expression of Matrix Metalloproteinases (MMPs) and Tissue Inhibitors of Metalloproteinases (TIMPs) in Healthy and Diseased Human Gingiva

Ejeil, A., Changotade, S., Ghomrasseni, S., et al. (2003) · Journal of Periodontology · doi:10.1902/jop.2003.74.2.188 · Cited by 202 · see citing works