Effects of increased opportunity for physical exercise and learning experiences on recognition memory and brain-derived neurotrophic factor levels in brain and serum of rats

Neural consequences of enviromental enrichment

van Praag, H., Kempermann, G., & Gage, F. H. (2000) · Nature Reviews Neuroscience · doi:10.1038/35044558 · Cited by 2,468 · see citing works

Transport of brain-derived neurotrophic factor across the blood–brain barrier

Pan, W., Banks, W. A., Fasold, M. B., Bluth, J., & Kastin, A. J. (1998) · Neuropharmacology · doi:10.1016/s0028-3908(98)00141-5 · Cited by 1,354 · see citing works

BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders

Mattson, M. P., Maudsley, S., & Martin, B. (2004) · Trends in Neurosciences · doi:10.1016/j.tins.2004.08.001 · Cited by 942 · see citing works

Evidence for a release of brain-derived neurotrophic factor from the brain during exercise

Rasmussen, P., Brassard, P., Adser, H., Pedersen, M. V., Leick, L., Hart, E., Secher, N. H., Pedersen, B. K., & Pilegaard, H. (2009) · Experimental Physiology · doi:10.1113/expphysiol.2009.048512 · Cited by 914 · see citing works

Behavioural and neurochemical effects of post-weaning social isolation in rodents—Relevance to developmental neuropsychiatric disorders

Fone, K. C. F., & Porkess, M. V. (2008) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2008.03.003 · Cited by 864 · see citing works

Postnatal Developmental Profile of Brain-Derived Neurotrophic Factor in Rat Brain and Platelets

Karege, F., Schwald, M., & Cisse, M. (2002) · Neuroscience Letters · doi:10.1016/s0304-3940(02)00529-3 · Cited by 799 · see citing works

High impact running improves learning

Winter, B., Breitenstein, C., Mooren, F. C., Voelker, K., Fobker, M., Lechtermann, A., Krueger, K., Fromme, A., Korsukewitz, C., Flöel, A., et al. (2006) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2006.11.003 · Cited by 796 · see citing works

Blood BDNF Concentrations Reflect Brain-Tissue BDNF Levels across Species

Klein, A. B., Williamson, R., Santini, M. A., Clemmensen, C., Ettrup, A., Rios, M., Knudsen, G. M., & Aznar, S. (2011) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145710000738 · Cited by 726 · see citing works

Brain-derived neurotrophic factor (BDNF) is required for the enhancement of hippocampal neurogenesis following environmental enrichment

Rossi, C., Angelucci, A., Costantin, L., Braschi, C., Mazzantini, M., Babbini, F., Fabbri, M. E., Tessarollo, L., Maffei, L., Berardi, N., et al. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.05059.x · Cited by 619 · see citing works

Brain-derived neurotrophic factor is associated with age-related decline in hippocampal volume.

Erickson, K. I., Prakash, R. S., Voss, M. W., Chaddock, L., Heo, S., McLaren, M., Pence, B. D., Martin, S. A., Vieira, V. J., Woods, J. A., et al. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.6251-09.2010 · Cited by 604 · see citing works

Long-Term Environmental Enrichment Leads to Regional Increases in Neurotrophin Levels in Rat Brain

Ickes, B. R., Pham, T. M., Sanders, L., Albeck, D. S., Mohammed, A. H. S., & Granholm, A. (2000) · Experimental Neurology · doi:10.1006/exnr.2000.7415 · Cited by 541 · see citing works

Environmental enrichment in mice decreases anxiety, attenuates stress responses and enhances natural killer cell activity

Benaroya‐Milshtein, N., Hollander, N., Apter, A., Kukulansky, T., Raz, N., Wilf, A., Yaniv, I., & Pick, C. G. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03587.x · Cited by 439 · see citing works

Serum levels of brain-derived neurotrophic factor in major depressive disorder: state–trait issues, clinical features and pharmacological treatment

Molendijk, M. L., Bus, B. A. A., Spinhoven, P., Penninx, B. W. J. H., Kenis, G., Prickaerts, J., Voshaar, R. O., & Elzinga, B. M. (2011) · Molecular Psychiatry · doi:10.1038/mp.2010.98 · Cited by 437 · see citing works

Behavioral, neurochemical and endocrinological characterization of the early social isolation syndrome

Heidbreder, C. A., Weiss, I. C., Domeney, A. M., Pryce, C., Homberg, J., Hedou, G., Feldon, J., Moran, M. C., & Nelson, P. (2000) · Neuroscience · doi:10.1016/s0306-4522(00)00336-5 · Cited by 404 · see citing works

Aging, plasticity and environmental enrichment: Structural changes and neurotransmitter dynamics in several areas of the brain

Mora, F., Segovia, G., & Arco, A. D. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2007.03.011 · Cited by 401 · see citing works

Serum brain-derived neurotrophic factor is decreased in bipolar disorder during depressive and manic episodes

Cunha, A. B. M., Frey, B. N., Andreazza, A. C., Goi, J. D., Rosa, A. R., Gonçalves, C. A., Santin, A. M. P., & Kapczinski, F. P. (2006) · Neuroscience Letters · doi:10.1016/j.neulet.2005.12.085 · Cited by 391 · see citing works

Brain-derived neurotrophic factor as a state-marker of mood episodes in bipolar disorders: A systematic review and meta-regression analysis

Fernandes, B. S., Gama, C. S., Maria Ceresér, K., Yatham, L. N., Fries, G. R., Colpo, G., de Lucena, D., Kunz, M., Gomes, F. A., & Kapczinski, F. (2011) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2011.03.002 · Cited by 389 · see citing works

Increased expression of brain-derived neurotrophic factor mRNA in rat hippocampus is associated with improved spatial memory and enriched environment

Falkenberg, T., Mohammed, A. K., Henriksson, B. G., Persson, H., Winblad, B. G., & Lindefors, N. (1992) · Neuroscience Letters · doi:10.1016/0304-3940(92)90494-r · Cited by 388 · see citing works

Environmental Enrichment Modifies the PKA-Dependence of Hippocampal LTP and Improves Hippocampus-Dependent MemoryPreprint

Duffy, S. N., Craddock, K. J., Abel, T. G., & Nguyen, P. (2001) · Learning & Memory · doi:10.1101/lm.36301 · Cited by 342 · see citing works

Stage-dependent BDNF serum concentrations in Alzheimer’s disease

Laske, C., Stransky, E., Leyhe, T., Eschweiler, G. W., Wittorf, A., Richartz, E., Bartels, M., Buchkremer, G., & Schott, K. J. (2005) · Journal of Neural Transmission · doi:10.1007/s00702-005-0397-y · Cited by 324 · see citing works

Brain-Derived Neurotrophic Factor: A Newly Described Mediator of Angiogenesis

Kermani, P., & Hempstead, B. L. (2007) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2007.03.002 · Cited by 312 · see citing works

Endurance training increases plasma brain-derived neurotrophic factor concentration in young healthy men.

Zoladz, J. A., Pilc, A., Majerczak, J., Grandys, M., Zapart-Bukowska, J., & Duda, K. (2008) · PubMed · Cited by 309 · see citing works

Influence of Postweaning Social Isolation in the Rat on Brain Development, Conditioned Behavior, and Neurotransmission

Lapiz, M. D. S., Fulford, A., Muchimapura, S., Mason, R., Parker, T., & Marsden, C. A. (2003) · Neuroscience and Behavioral Physiology · doi:10.1023/a:1021171129766 · Cited by 305 · see citing works

Low plasma BDNF is associated with suicidal behavior in major depression

Kim, Y.-K., Lee, H.-P., Won, S.-D., Park, E.-Y., Lee, H.-Y., Lee, B.-H., Lee, S.-W., Yoon, D., Han, C., Kim, D.-J., et al. (2007) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2006.06.024 · Cited by 300 · see citing works

Serum levels of brain-derived neurotrophic factor correlate with motor impairment in Parkinson’s disease

Scalzo, P., Kümmer, A., Bretas, T. L., Cardoso, F., & Teixeira, A. L. (2010) · Journal of Neurology · doi:10.1007/s00415-009-5357-2 · Cited by 299 · see citing works

Therapeutic and protective effect of environmental enrichment against psychogenic and neurogenic stress

Fox, C., Merali, Z., & Harrison, C. R. (2006) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.08.016 · Cited by 283 · see citing works

Correlations and Discrepancies Between Serum and Brain Tissue Levels of Neurotrophins after Electroconvulsive Treatment in Rats

Sartorius, A., Hellweg, R., Litzke, J., Vogt, M., Dormann, C., Vollmayr, B., Danker-Hopfe, H., & Gass, P. (2009) · Pharmacopsychiatry · doi:10.1055/s-0029-1224162 · Cited by 276 · see citing works

Decreased BDNF levels in CSF of drug-naive first-episode psychotic subjects: correlation with plasma BDNF and psychopathology

Pillai, A., Kale, A. A., Joshi, S., Naphade, N. M., Raju, M. S. V. K., Nasrallah, H. A., & Mahadik, S. P. (2009) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145709991015 · Cited by 273 · see citing works

Changes in brain nerve growth factor levels and nerve growth factor receptors in rats exposed to environmental enrichment for one year

Pham, T. M., Ickes, B. R., Albeck, D. S., Söderström, S., Granholm, A.-C., & Mohammed, A. H. (1999) · Neuroscience · doi:10.1016/s0306-4522(99)00316-4 · Cited by 262 · see citing works

Contribution of the D-Serine-dependent pathway to the cellular mechanisms underlying cognitive aging

Potier, B. (2010) · Frontiers in Aging Neuroscience · doi:10.3389/neuro.24.001.2010 · Cited by 217 · see citing works

Isolation rearing induces recognition memory deficits accompanied by cytoskeletal alterations in rat hippocampus

Bianchi, M., Fone, K. C. F., Azmi, N., Heidbreder, C. A., Hagan, J. J., & Marsden, C. A. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.05170.x · Cited by 191 · see citing works

Alzheimers Disease (AD) and Mild Cognitive Impairment (MCI) Patients are Characterized by Increased BDNF Serum Levels

Angelucci, F., Spalletta, G., Iulio, F. D., Ciaramella, A., Salani, F., Varsi, A. E., Gianni, W., Sancesario, G., Caltagirone, C., & Bossù, P. (2010) · Current Alzheimer Research · doi:10.2174/156720510790274473 · Cited by 187 · see citing works

Enduring and sex-specific effects of adolescent social isolation in rats on adult stress reactivity

Weintraub, A. Y., Singaravelu, J., & Bhatnagar, S. (2010) · Brain Research · doi:10.1016/j.brainres.2010.04.068 · Cited by 186 · see citing works

Environmental influences on brain neurotrophins in rats

Pham, T. M., Winblad, B. G., Granholm, A., & Mohammed, A. H. S. (2002) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(02)00783-9 · Cited by 184 · see citing works

Higher BDNF serum levels predict slower cognitive decline in Alzheimer's disease patients

Laske, C., Stellos, K., Hoffmann, N., Stransky, E., Straten, G., Eschweiler, G. W., & Leyhe, T. (2011) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145710001008 · Cited by 180 · see citing works

Neurotoxic methamphetamine regimen severely impairs recognition memory in rats

Schröder, N., O’Dell, S. J., & Marshall, J. F. (2003) · Synapse · doi:10.1002/syn.10210 · Cited by 179 · see citing works

Functional Outcome in Rats Transferred to an Enriched Environment 15 Days After Focal Brain Ischemia

Johansson, B. B. (1996) · Stroke · doi:10.1161/01.str.27.2.324 · Cited by 177 · see citing works

Influence of differential housing on emotional behaviour and neurotrophin levels in mice

Zhu, S., Yee, B. K., Nyffeler, M., Winblad, B. G., Feldon, J., & Mohammed, A. H. S. (2006) · Behavioural Brain Research · doi:10.1016/j.bbr.2005.11.024 · Cited by 174 · see citing works

Impact of enriched-environment housing on brain-derived neurotrophic factor and on cognitive performance after a transient global ischemia

Gobbo, O. L., & O’Mara, S. M. (2003) · Behavioural Brain Research · doi:10.1016/j.bbr.2003.10.017 · Cited by 170 · see citing works

Donald O. Hebb's synapse and learning rule: a history and commentary

Cooper, S. J. (2004) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2004.09.009 · Cited by 159 · see citing works

Correlation Between Serum Brain-Derived Neurotrophic Factor Level and An In Vivo Marker of Cortical Integrity

Lang, U. E., Hellweg, R., Seifert, F. C., Schubert, F., & Gallinat, J. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.01.002 · Cited by 156 · see citing works

Memantine reduces oxidative damage and enhances long-term recognition memory in aged rats

Dias, C. P., de Lima, M. N. M., Presti-Torres, J., Dornelles, A. D. S., Garcia, V. A., Scalco, F. S., Guimarães, M. R., Constantino, L. D. S., Budni, P., Dal‐Pizzol, F., et al. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.03.018 · Cited by 148 · see citing works

BDNF expression in perirhinal cortex is associated with exercise-induced improvement in object recognition memory

Hopkins, M. E., & Bucci, D. J. (2010) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2010.06.006 · Cited by 139 · see citing works

Chronic corticosterone decreases brain-derived neurotrophic factor (BDNF) mRNA and protein in the hippocampus, but not in the frontal cortex, of the rat

Jacobsen, J. P. R., & Mørk, A. (2006) · Brain Research · doi:10.1016/j.brainres.2006.06.077 · Cited by 139 · see citing works

Environmental influences on functional outcome after a cortical infarct in the rat

Risedal, A., Mattsson, B., Dahlqvist, P. M., Nordborg, C., Olsson, T., & Johansson, B. B. (2002) · Brain Research Bulletin · doi:10.1016/s0361-9230(02)00796-7 · Cited by 136 · see citing works

An environmental enrichment model for mice

Sztainberg, Y., & Chen, A. (2010) · Nature Protocols · doi:10.1038/nprot.2010.114 · Cited by 132 · see citing works

Environmental enrichment, prefrontal cortex, stress, and aging of the brain

Segovia, G., Arco, A. D., & Mora, F. (2009) · Journal of Neural Transmission · doi:10.1007/s00702-009-0214-0 · Cited by 130 · see citing works

Long-term effects of the periadolescent environment on exploratory activity and aggressive behaviour in mice: social versus physical enrichment

Pietropaolo, S., Branchi, I., Cirulli, F., Chiarotti, F., Aloe, L., & Alleva, E. (2004) · Physiology & Behavior · doi:10.1016/j.physbeh.2004.02.022 · Cited by 128 · see citing works

Complex mental activity and the aging brain: molecular, cellular and cortical network mechanisms.

Valenzuela, M., Breakspear, M., & Sachdev, P. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2007.07.007 · Cited by 123 · see citing works

Early social enrichment augments adult hippocampal BDNF levels and survival of BrdU‐positive cells while increasing anxiety‐ and “depression”‐like behavior

Branchi, I., D’Andrea, I., Sietzema, J. G., Fiore, M., Fausto, V. D., Aloe, L., & Alleva, E. (2006) · Journal of Neuroscience Research · doi:10.1002/jnr.20789 · Cited by 123 · see citing works

Enriched environment during development is protective against lead-induced neurotoxicity

Schneider, J. S., Lee, M. H., Anderson, D. W., Zuck, L., & Lidsky, T. I. (2001) · Brain Research · doi:10.1016/s0006-8993(00)03249-2 · Cited by 118 · see citing works

Recognition memory impairment and brain oxidative stress induced by postnatal iron administration

de Lima, M. N. M., Polydoro, M., Laranja, D. C., Bonatto, F., Bromberg, E., Moreira, J. C. F., Dal‐Pizzol, F., & Schröder, N. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.04083.x · Cited by 116 · see citing works

Temporary inactivation reveals an essential role of the dorsal hippocampus in consolidation of object recognition memory

de Lima, M. N., Luft, T., Roesler, R., & Schröder, N. (2006) · Neuroscience Letters · doi:10.1016/j.neulet.2006.06.044 · Cited by 113 · see citing works

Altering BDNF expression by genetics and/or environment: Impact for emotional and depression-like behaviour in laboratory mice

Chourbaji, S., Brandwein, C., & Gass, P. (2010) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.07.003 · Cited by 109 · see citing works

Relationship of serum brain-derived neurotrophic factor (BDNF) and health-related lifestyle in healthy human subjects

Chan, K. L., Tong, R. K., & Yip, S. P. (2008) · Neuroscience Letters · doi:10.1016/j.neulet.2008.10.013 · Cited by 107 · see citing works

Reversal of age-related deficits in object recognition memory in rats with l-deprenyl

de Lima, M. N. M., Laranja, D. C., Caldana, F., Bromberg, E., Roesler, R., & Schröder, N. (2005) · Experimental Gerontology · doi:10.1016/j.exger.2005.03.004 · Cited by 103 · see citing works

Involvement of BDNF in age-dependent alterations in the hippocampus

Halbach, O. V. B. U. (2010) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2010.00036 · Cited by 101 · see citing works

Depressive behavior and selective downregulation of serotonin receptor expression after early-life seizures: Reversal by environmental enrichment

Koh, S., Magid, R., Chung, H., Stine, C. D., & Wilson, D. N. (2006) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2006.11.008 · Cited by 101 · see citing works

Decreased serum brain-derived neurotrophic factor in trained men

Nofuji, Y., Suwa, M., Moriyama, Y., Nakano, H., Ichimiya, A., Nishichi, R., Sasaki, H., Radak, Z. O., & Kumagai, S. (2008) · Neuroscience Letters · doi:10.1016/j.neulet.2008.03.057 · Cited by 101 · see citing works

Enriched environment influences hormonal status and hippocampal brain derived neurotrophic factor in a sex dependent manner

Bakoš, J., Hlaváčová, N., Rajman, M., Ondičová, K., Koros, C., Kitraki, E., Steinbusch, H. W. M., & Ježová, D. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2009.08.054 · Cited by 96 · see citing works

Potential for Unintended Consequences of Environmental Enrihment for Laboratory Animals and Research Results

Bayne, K. A. L. (2005) · ILAR Journal · doi:10.1093/ilar.46.2.129 · Cited by 96 · see citing works

Brain-derived neurotrophic factor, stress and depression: A minireview

Yuluğ, B., Ozan, E., Gönül, A. S., & Kılıç, E. (2008) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2008.12.002 · Cited by 89 · see citing works

A “deficient environment” in prenatal life may compromise systems important for cognitive function by affecting BDNF in the hippocampus

Gómez‐Pinilla, F., & Vaynman, S. (2005) · Experimental Neurology · doi:10.1016/j.expneurol.2004.12.001 · Cited by 88 · see citing works

The mGluR2/3 agonist LY379268 reverses post-weaning social isolation-induced recognition memory deficits in the rat

Jones, C. A., Brown, A. M., Auer, D. P., & Fone, K. C. F. (2010) · Psychopharmacology · doi:10.1007/s00213-010-1931-7 · Cited by 85 · see citing works

Formation and Evolution of the Chordate Neurotrophin and Trk Receptor Genes

Hallböök, F., Wilson, K., Thorndyke, M. C., & Olinski, R. P. (2006) · Brain Behavior and Evolution · doi:10.1159/000094083 · Cited by 84 · see citing works

Interaction between isolation rearing and social development on exploratory behavior in male rats

Arakawa, H. (2005) · Behavioural Processes · doi:10.1016/j.beproc.2005.07.002 · Cited by 79 · see citing works

Early Enriched Environment Promotes Neonatal GABAergic Neurotransmission and Accelerates Synapse Maturation

He, S., Ma, J., Liu, N., & Yu, X. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.6375-09.2010 · Cited by 71 · see citing works

Enriched Environment Improves Motor Function and Increases Neurotrophins in Hemicerebellar Lesioned Rats

Gelfo, F., Cutuli, D., Foti, F., Laricchiuta, D., Bartolo, P. D., Caltagirone, C., Petrosini, L., & Angelucci, F. (2010) · Neurorehabilitation and neural repair · doi:10.1177/1545968310380926 · Cited by 57 · see citing works

Exposure to environmental enrichment elicits differential hippocampal cell proliferation: Role of individual responsiveness to anxiety

Leal‐Galicia, P., Saldı́var-González, A., Morimoto, S., & Arias, C. (2007) · Developmental Neurobiology · doi:10.1002/dneu.20322 · Cited by 55 · see citing works

Reversion of age-related recognition memory impairment by iron chelation in rats

de Lima, M. N. M., Dias, C. P., Torres, J. P., Dornelles, A. D. S., Garcia, V. A., Scalco, F. S., Guimarães, M. R., Petry, R. C., Bromberg, E., Constantino, L. D. S., et al. (2007) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2007.02.006 · Cited by 55 · see citing works

Selegiline protects against recognition memory impairment induced by neonatal iron treatment

DELIMA, M., Laranja, D. C., Caldana, F., Grazziotin, M. M., GARCIA, V., Dal‐Pizzol, F., Bromberg, E., & Schröder, N. (2005) · Experimental Neurology · doi:10.1016/j.expneurol.2005.07.017 · Cited by 45 · see citing works

Effect of “enriched environment” during development on adult rat behavior and response to the dopamine receptor agonist apomorphine

Hoffmann, L., Schütte, S. R. M., Koch, M., & Schwabe, K. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.11.035 · Cited by 45 · see citing works

Something old, something new: BDNF-induced neuron survival requires TRPC channel function

Sossin, W. S., & Barker, P. A. (2007) · Nature Neuroscience · doi:10.1038/nn0507-537 · Cited by 44 · see citing works

Environmental Enrichment Alters Neurotrophin Levels After Fetal Alcohol Exposure in Rats

Parks, E. A., McMechan, A. P., Hannigan, J. H., & Berman, R. F. (2008) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2008.00759.x · Cited by 25 · see citing works

Environmental Influence on Gene Expression and Recovery from Cerebral Ischemia

Johansson, B. B., Zhao, L. R., & Mattsson, B. (1999) · Acta neurochirurgica. Supplementum · doi:10.1007/978-3-7091-6391-7_8 · Cited by 24 · see citing works

Brain-Derived Neurotrophic Factor in Brain Disorders: Focus on Neuroinflammation

Lima Giacobbo, B., Doorduin, J., Klein, H. C., Dierckx, R. A. J. O., Bromberg, E., & de Vries, E. F. J. (2019) · Molecular Neurobiology · doi:10.1007/s12035-018-1283-6 · Cited by 750 · see citing works

Environmental enrichment and the sensory brain: The role of enrichment in remediating brain injury

Alwis, D. S., & Rajan, R. (2014) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2014.00156 · Cited by 129 · see citing works

Adult Hippocampal Neurogenesis along the Dorsoventral Axis Contributes Differentially to Environmental Enrichment Combined with Voluntary Exercise in Alleviating Chronic Inflammatory Pain in Mice

Zheng, J., Jiang, Y., Xu, L., Ma, L., Liu, F., Cui, S., Cai, J., Liao, F., Wan, Y., & Yi, M. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.3333-16.2017 · Cited by 114 · see citing works

Alleviation of chronic neuropathic pain by environmental enrichment in mice well after the establishment of chronic pain

Vachon, P., Millecamps, M., Low, L. A., Thompsosn, S. J., Pailleux, F., Beaudry, F., Bushnell, C. M., & Stone, L. S. (2013) · Behavioral and Brain Functions · doi:10.1186/1744-9081-9-22 · Cited by 111 · see citing works

Staging bipolar disorder: clinical, biochemical, and functional correlates

Grande, I., Magalhães, P. V. D. S., Chendo, I., Stertz, L., Panizzutti, B., Colpo, G. D., Rosa, A. R., Gama, C. S., Kapczinski, F. P., & Vieta, E. (2014) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.12268 · Cited by 99 · see citing works

Environmental Enrichment Improves Novel Object Recognition and Enhances Agonistic Behavior in Male Mice

Mesa‐Gresa, P., Pérez‐Martinez, A., & Redolat, R. (2013) · Aggressive Behavior · doi:10.1002/ab.21481 · Cited by 66 · see citing works

Physical Activity, Cognitive Function, and Brain Health: What Is the Role of Exercise Training in the Prevention of Dementia?

Gregory, S. M., Parker, B. A., & Thompson, P. D. (2012) · Brain Sciences · doi:10.3390/brainsci2040684 · Cited by 64 · see citing works

Environmental enrichment cognitive neuroprotection in an experimental model of cerebral ischemia: biochemical and molecular aspects

Gonçalves, L. V., Herlinger, A. L., Ferreira, T. A. A., Coitinho, J. B., Pires, R. G. W., & Martins-Silva, C. (2018) · Behavioural Brain Research · doi:10.1016/j.bbr.2018.04.023 · Cited by 52 · see citing works

Environmental Enrichment Effects on the Brain-Derived Neurotrophic Factor Expression in Healthy Condition, Alzheimer’s Disease, and Other Neurodegenerative Disorders

Cutuli, D., Landolfo, E., Petrosini, L., & Gelfo, F. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-215193 · Cited by 46 · see citing works

Social isolation and social support at adulthood affect epigenetic mechanisms, brain-derived neurotrophic factor levels and behavior of chronically stressed rats

Borges, J. V., de Freitas, B. S., Antoniazzi, V., dos Santos, C. D. S., Vedovelli, K., Pires, V. N., Paludo, L., de Lima, M. N. M., & Bromberg, E. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2019.03.025 · Cited by 44 · see citing works

Exposure to an enriched environment facilitates motor recovery and prevents short-term memory impairment and reduction of striatal BDNF in a progressive pharmacological model of parkinsonism in mice

Campêlo, C. L. D. C., dos Santos, J. R., Silva, A. F., Dierschnabel, A. L., de Pontes, A. L. B., Cavalcante, J. S., Ribeiro, A. M., & Silva, R. H. (2017) · Behavioural Brain Research · doi:10.1016/j.bbr.2017.04.028 · Cited by 35 · see citing works

Does brain-derived neurotrophic factor mediate the effects of exercise on memory?

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Corticosterone levels and behavioral changes induced by simultaneous exposure to chronic social stress and enriched environments in NMRI male mice

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The pesticide fipronil injected into the substantia nigra of male rats decreases striatal dopamine content: A neurochemical, immunohistochemical and behavioral study

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Environmental enrichment enhances sociability by regulating glutamate signaling pathway through GR by epigenetic mechanisms in amygdala of Indian field mice Mus booduga

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The Effect of Two Types of Exercise Preconditioning on the Expression of TrkB, TNF‐α, and MMP2 Genes in Rats with Stroke

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PDE5 Inhibition Improves Object Memory in Standard Housed Rats but Not in Rats Housed in an Enriched Environment: Implications for Memory Models?

Akkerman, S., Prickaerts, J., Bruder, A. K., Wolfs, K. H. M., Vry, J. D., Vanmierlo, T., & Blokland, A. (2014) · PLoS ONE · doi:10.1371/journal.pone.0111692 · Cited by 12 · see citing works

Serum BDNF levels in unaffected first-degree relatives of patients with bipolar disorder

Nery, F. G., Gigante, A. D., Amaral, J. A., Fernandes, F. B. F., Berutti, M., de Almeida, K. M., Stertz, L., Bristot, G., Kapczinski, F. P., & Lafer, B. (2016) · Brazilian Journal of Psychiatry · doi:10.1590/1516-4446-2015-1801 · Cited by 10 · see citing works

Comparison of serum brain-derived neurotrophic factor in dogs with and without separation anxiety

Moesta, A., Kim, G., Wilson-Frank, C. R., Weng, H., & Ogata, N. (2019) · Journal of Veterinary Behavior · doi:10.1016/j.jveb.2019.10.013 · Cited by 9 · see citing works

Amygdala – and serum – neurotrophic factor levels depend on rearing condition in male rats

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The Effect of Two Types of Training Programs on the Expression of TrkB, Bax and Bcl-2 Genes in Male Rats After Induction of Cerebral Ischemia

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Bases moleculares envolvidas na neuroproteção causada pela exposição a um ambiente enriquecido em modelo animal de isquemia cerebral

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Preventive Effects of Endurance and Cognitive-Motor Training on TREM2 Expression and IL-33 Levels in Vascular Dementia Rats

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Efeitos do ambiente enriquecido nos níveis centrais e periférico de BDNF e sua relação com o desempenho na tarefa de reconhecimento de objetos em ratos

Vedovelli, K. (2011) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)

Long-term environmental modifications affect BDNF concentrations in rat hippocampus, but not in serum

Giacobbo, B. L., de Freitas, B. S., Vedovelli, K., Schlemmer, L. M., Pires, V. N., Antoniazzi, V., dos Santos, C. D. S., Paludo, L., Borges, J. V., de Lima, D. B., et al. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2019.111965 · Cited by 21 · see citing works

Effects of enriched environment on the capacity of learning and memory and expression of BDNF expression of CA1 hippocampus in rats

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EFFECT OF CONTINUOUS ENVIRONMENTAL ENRICHMENT AND AEROBIC EXERCISE ON RAT PLASMA AND HIPPOCAMPAL BRAIN‑DERIVED NEUROTROPHIC FACTOR

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