Environmental enrichment and the sensory brain: The role of enrichment in remediating brain injury

Exercise training increases size of hippocampus and improves memory

Erickson, K. I., Voss, M. W., Prakash, R. S., Basak, C., Szabo, A., Chaddock, L., Kim, J. S., Heo, S., Alves, H., White, S. M., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1015950108 · Cited by 4,855 · see citing works

More hippocampal neurons in adult mice living in an enriched environment

Kempermann, G., Kuhn, H. G., & Gage, F. H. (1997) · Nature · doi:10.1038/386493a0 · Cited by 3,513 · see citing works

Traumatic brain injury in the United States : emergency department visits, hospitalizations, and deaths, 2002-2006

National Center for Injury Prevention and Control (U.S.). Division of Injury Response., Faul, M., Wald, M. M., Wu, L., & Coronado, V. G. (2010) · doi:10.15620/cdc.5571 · Cited by 3,494 · see citing works

The period of susceptibility to the physiological effects of unilateral eye closure in kittens

Hubel, D. H., & Wiesel, T. N. (1970) · The Journal of Physiology · doi:10.1113/jphysiol.1970.sp009022 · Cited by 3,030 · see citing works

Running enhances neurogenesis, learning, and long-term potentiation in mice

van Praag, H., Christie, B. R., Sejnowski, T. J., & Gage, F. H. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.23.13427 · Cited by 2,904 · see citing works

Neural consequences of enviromental enrichment

van Praag, H., Kempermann, G., & Gage, F. H. (2000) · Nature Reviews Neuroscience · doi:10.1038/35044558 · Cited by 2,468 · see citing works

CORTICAL PLASTICITY: From Synapses to Maps

Buonomano, D. V., & Merzenich, M. M. (1998) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.21.1.149 · Cited by 2,083 · cited 1× · see citing works

Enriched environments, experience-dependent plasticity and disorders of the nervous system

Nithianantharajah, J., & Hannan, A. J. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1970 · Cited by 1,771 · see citing works

The self-tuning neuron: synaptic scaling of excitatory synapses

Turrigiano, G. G. (2008) · Cell · doi:10.1016/j.cell.2008.10.008 · Cited by 1,533 · see citing works

Long-Lasting Neurotrophin-Induced Enhancement of Synaptic Transmission in the Adult Hippocampus

Kang, H., & Schuman, E. M. (1995) · Science · doi:10.1126/science.7886457 · Cited by 1,354 · see citing works

Plasticity in the frequency representation of primary auditory cortex following discrimination training in adult owl monkeys

Recanzone, G., Schreiner, C., & Merzenich, M. (1993) · The Journal of Neuroscience · doi:10.1523/jneurosci.13-01-00087.1993 · Cited by 1,266 · see citing works

BDNF Regulates the Maturation of Inhibition and the Critical Period of Plasticity in Mouse Visual Cortex

Huang, Z. J., Kirkwood, A., Pizzorusso, T., Porciatti, V., Morales, B., Bear, M. F., Maffei, L., & Tonegawa, S. (1999) · Cell · doi:10.1016/s0092-8674(00)81509-3 · Cited by 1,198 · see citing works

Rapid formation and selective stabilization of synapses for enduring motor memories

Xu, T., Yu, X., Perlik, A. J., Tobin, W. F., Zweig, J. A., Tennant, K., Jones, T., & Zuo, Y. (2009) · Nature · doi:10.1038/nature08389 · Cited by 1,193 · see citing works

Experience-Induced Neurogenesis in the Senescent Dentate Gyrus

Kempermann, G., Kuhn, H. G., & Gage, F. H. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-09-03206.1998 · Cited by 1,150 · see citing works

Clinical trials in head injury

Narayan, R. K., Michel, M. E., Ansell, B., Baethmann, A., Biegon, A., Bracken, M. B., Bullock, M. R., Choi, S. C., Clifton, G. L., Contant, C. F., et al. (2002) · Journal of Neurotrauma · doi:10.1089/089771502753754037 · Cited by 913 · cited 2× · see citing works

Plasticity of Sensory and Motor Maps in Adult Mammals

Kaas, J. H. (1991) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.14.030191.001033 · Cited by 913 · see citing works

Local GABA Circuit Control of Experience-Dependent Plasticity in Developing Visual Cortex

Hensch, T. K., Fagiolini, M., Mataga, N., Stryker, M. P., Baekkeskov, S., & Kash, S. F. (1998) · Science · doi:10.1126/science.282.5393.1504 · Cited by 910 · see citing works

The antidepressant fluoxetine restores plasticity in the adult visual cortex

Vetencourt, J. F. M., Sale, A., Viegi, A., Baroncelli, L., De Pasquale, R., F. O'Leary, O., Castrén, E., & Maffei, L. (2008) · Science · doi:10.1126/science.1150516 · Cited by 890 · see citing works

Environmental Enrichment Reduces Aβ Levels and Amyloid Deposition in Transgenic Mice

Lazarov, O., Robinson, J., Tang, Y.-P., Hairston, I. S., Korade-Mirnics, Z., Lee, V. M.-Y., Hersh, L. B., Sapolsky, R. M., Mirnics, K., & Sisodia, S. S. (2005) · Cell · doi:10.1016/j.cell.2005.01.015 · Cited by 885 · see citing works

Cognitive Reserve and Lifestyle

Scarmeas, N., & Stern, Y. (2003) · Journal of Clinical and Experimental Neuropsychology · doi:10.1076/jcen.25.5.625.14576 · Cited by 869 · see citing works

Social relationships, social support, and patterns of cognitive aging in healthy, high-functioning older adults: MacArthur Studies of Successful Aging.

Seeman, T. E., Lusignolo, T. M., Albert, M., & Berkman, L. (2001) · Health Psychology · doi:10.1037/0278-6133.20.4.243 · Cited by 855 · see citing works

Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male Sprague-Dawley rats in vivo

Farmer, J., Zhao, X., van Praag, H., Wodtke, K., Gage, F. H., & Christie, B. R. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2003.09.029 · Cited by 836 · see citing works

Homeostatic plasticity in neuronal networks: the more things change, the more they stay the same

Turrigiano, G. G. (1999) · Trends in Neurosciences · doi:10.1016/s0166-2236(98)01341-1 · Cited by 823 · see citing works

Essential Role for TrkB Receptors in Hippocampus-Mediated Learning

Minichiello, L., Korte, M., Wolfer, D., Kühn, R., Unsicker, K., Cestari, V., Rossi-Arnaud, C., Lipp, H.-P., Bonhoeffer, T., & Klein, R. (1999) · Neuron · doi:10.1016/s0896-6273(00)80853-3 · Cited by 799 · see citing works

Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective

Young, D., Lawlor, P. A., Leone, P., Dragunow, M., & During, M. J. (1999) · Nature Medicine · doi:10.1038/7449 · Cited by 731 · see citing works

DIFFUSE DEGENERATION OF THE CEREBRAL WHITE MATTER IN SEVERE DEMENTIA FOLLOWING HEAD INJURY

Strich, S. J. (1956) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.19.3.163 · Cited by 728 · see citing works

Inhibitory threshold for critical-period activation in primary visual cortex

Fagiolini, M., & Hensch, T. K. (2000) · Nature · doi:10.1038/35004582 · Cited by 716 · see citing works

Inflammatory response in acute traumatic brain injury: a double-edged sword

Morganti-Kossmann, M., Rancan, M., Stahel, P., & Kossmann, T. (2002) · Current Opinion in Critical Care · doi:10.1097/00075198-200204000-00002 · Cited by 702 · see citing works

Hippocampus-specific deletion of BDNF in adult mice impairs spatial memory and extinction of aversive memories

Heldt, S. A., Stanek, L., Chhatwal, J. P., & Ressler, K. J. (2007) · Molecular Psychiatry · doi:10.1038/sj.mp.4001957 · Cited by 684 · see citing works

Spatial memory performances of aged rats in the water maze predict levels of hippocampal neurogenesis

Drapeau, E., Mayo, W., Aurousseau, C., Moal, M. L., Piazza, P., & Abrous, D. N. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2334169100 · Cited by 657 · see citing works

New treatments in neurorehabiliation founded on basic research

Taub, E., Uswatte, G., & Elbert, T. R. (2002) · Nature reviews. Neuroscience · doi:10.1038/nrn754 · Cited by 643 · see citing works

Brain-derived neurotrophic factor (BDNF) is required for the enhancement of hippocampal neurogenesis following environmental enrichment

Rossi, C., Angelucci, A., Costantin, L., Braschi, C., Mazzantini, M., Babbini, F., Fabbri, M. E., Tessarollo, L., Maffei, L., Berardi, N., et al. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.05059.x · Cited by 619 · see citing works

Effects of environmental enrichment on gene expression in the brain

Rampon, C., Jiang, C. H., Dong, H., Tang, Y., Lockhart, D. J., Schultz, P. G., Tsien, J. Z., & Hu, Y. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.23.12880 · Cited by 614 · see citing works

Enriched Rehabilitative Training Promotes Improved Forelimb Motor Function and Enhanced Dendritic Growth after Focal Ischemic Injury

Biernaskie, J. A., & Corbett, D. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-14-05272.2001 · Cited by 608 · see citing works

Exercise, brain, and cognition across the life span.

Voss, M. W., Nagamatsu, L. S., Liu-Ambrose, T., & Kramer, A. F. (2011) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00210.2011 · Cited by 601 · see citing works

Environmental Noise Retards Auditory Cortical Development

Chang, E. F., & Merzenich, M. M. (2003) · Science · doi:10.1126/science.1082163 · Cited by 573 · see citing works

Pattern of dendritic branching in occipital cortex of rats reared in complex environments

Greenough, W. T., & Volkmar, F. R. (1973) · Experimental Neurology · doi:10.1016/0014-4886(73)90090-3 · Cited by 536 · see citing works

Environmental Enrichment Mitigates Cognitive Deficits in a Mouse Model of Alzheimer's Disease

Jankowsky, J. L., Melnikova, T., Fadale, D. J., Xu, G. M., Slunt, H. H., Gonzales, V., Younkin, L. H., Younkin, S. G., Borchelt, D. R., & Savonenko, A. V. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.5080-04.2005 · Cited by 517 · see citing works

Rearing complexity affects branching of dendrites in the visual cortex of the rat

Volkmar, F. R., & Greenough, W. T. (1972) · Science · doi:10.1126/science.176.4042.1445 · Cited by 513 · see citing works

New neurons in the dentate gyrus are involved in the expression of enhanced long‐term memory following environmental enrichment

Bruel‐Jungerman, E., Laroche, S., & Rampon, C. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.03875.x · Cited by 505 · see citing works

Environmental enrichment promotes improved spatial abilities and enhanced dendritic growth in the rat

Leggio, M. G., Mandolesi, L., Federico, F., Spirito, F., Ricci, B., Gelfo, F., & Petrosini, L. (2005) · Behavioural Brain Research · doi:10.1016/j.bbr.2005.04.009 · Cited by 502 · see citing works

Delaying the onset of Huntington's in mice

van Dellen, A., Blakemore, C., Deacon, R., York, D. F., & Hannan, A. (2000) · Nature · doi:10.1038/35008142 · Cited by 499 · see citing works

Environmental Influences on Cognitive and Brain Plasticity During Aging

Kramer, A. F., Bherer, L., Colcombe, S. J., Dong, W., & Greenough, W. T. (2004) · The Journals of Gerontology Series A · doi:10.1093/gerona/59.9.m940 · Cited by 498 · see citing works

Environmental enrichment in adulthood promotes amblyopia recovery through a reduction of intracortical inhibition

Sale, A., Maya Vetencourt, J. F., Medini, P., Cenni, M. C., Baroncelli, L., De Pasquale, R., & Maffei, L. (2007) · Nature Neuroscience · doi:10.1038/nn1899 · Cited by 492 · see citing works

The impact of environmental enrichment in laboratory rats—Behavioural and neurochemical aspects

Simpson, J., & Kelly, J. P. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.04.002 · Cited by 480 · see citing works

Learning deficit in BDNF mutant mice.

Linnarsson, S., Björklund, A., & Ernfors, P. (1997) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1997.tb01687.x · Cited by 471 · see citing works

Why new neurons? Possible functions for adult hippocampal neurogenesis

Kempermann, G. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-03-00635.2002 · Cited by 469 · see citing works

Differential rearing effects on rat visual cortex synapses: I. Synaptic and neuronal density and synapses per neuron

Turner, A. M., & Greenough, W. T. (1985) · Brain Research · doi:10.1016/0006-8993(85)90525-6 · Cited by 459 · see citing works

Environmental enrichment in mice decreases anxiety, attenuates stress responses and enhances natural killer cell activity

Benaroya‐Milshtein, N., Hollander, N., Apter, A., Kukulansky, T., Raz, N., Wilf, A., Yaniv, I., & Pick, C. G. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03587.x · Cited by 439 · see citing works

Effects of differential experience on dendritic spine counts in rat cerebral cortex

Globus, A., Rosenzweig, M. R., Bennett, E. L., & Diamond, M. C. (1973) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0033910 · Cited by 436 · see citing works

Flow of excitation within rat barrel cortex on striking a single vibrissa

Armstrong‐James, M., Fox, K. D., & Das-Gupta, A. (1992) · Journal of Neurophysiology · doi:10.1152/jn.1992.68.4.1345 · Cited by 426 · see citing works

The effects of early experience on problem-solving at maturity

Hebb, D. O. (1947) · American Psychologist · Cited by 425 · see citing works

How Monocular Deprivation Shifts Ocular Dominance in Visual Cortex of Young Mice

Frenkel, M. Y., & Bear, M. F. (2004) · Neuron · doi:10.1016/j.neuron.2004.12.003 · Cited by 412 · see citing works

Critical-Period Plasticity in the Visual Cortex

Levelt, C. N., & Hübener, M. (2012) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-061010-113813 · Cited by 402 · see citing works

Increased expression of brain-derived neurotrophic factor mRNA in rat hippocampus is associated with improved spatial memory and enriched environment

Falkenberg, T., Mohammed, A. K., Henriksson, B. G., Persson, H., Winblad, B. G., & Lindefors, N. (1992) · Neuroscience Letters · doi:10.1016/0304-3940(92)90494-r · Cited by 388 · see citing works

Enduring cognitive, neurobehavioral and histopathological changes persist for up to one year following severe experimental brain injury in rats

Pierce, J. E. S., Smith, D. H., Trojanowski, J. Q., & McIntosh, T. K. (1998) · Neuroscience · doi:10.1016/s0306-4522(98)00142-0 · Cited by 385 · cited 1× · see citing works

Social grouping cannot account for cerebral effects of enriched environments

Rosenzweig, M. R., Bennett, E. L., Hébert, M., & Morimoto, H. (1978) · Brain Research · doi:10.1016/0006-8993(78)90340-2 · Cited by 383 · see citing works

Cognitive functioning ten years following traumatic brain injury and rehabilitation.

Draper, K., & Ponsford, J. (2008) · Neuropsychology · doi:10.1037/0894-4105.22.5.618 · Cited by 380 · see citing works

Clinical characteristics and pathophysiological mechanisms of focal and diffuse traumatic brain injury

Andriessen, T. M. J. C., Jacobs, B., & Vos, P. E. (2010) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2010.01164.x · Cited by 373 · see citing works

Development and plasticity of cortical areas and networks

Sur, M., & Leamey, C. A. (2001) · Nature reviews. Neuroscience · doi:10.1038/35067562 · Cited by 372 · see citing works

Differential rearing effects on rat visual cortex synapses.

Sirevaag, A. M., & Greenough, W. T. (1987) · Brain Research · doi:10.1016/0006-8993(87)91477-6 · Cited by 370 · see citing works

Effects of rearing complexity on dendritic branching in frontolateral and temporal cortex of the rat

Greenough, W. T., Volkmar, F. R., & Juraska, J. M. (1973) · Experimental Neurology · doi:10.1016/0014-4886(73)90278-1 · Cited by 370 · see citing works

Environmental Enrichment Rescues Protein Deficits in a Mouse Model of Huntington's Disease, Indicating a Possible Disease Mechanism

Spires‐Jones, T. L., Grote, H., Varshney, N. K., Cordery, P. M., van Dellen, A., Blakemore, C. B., & Hannan, A. J. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.1658-03.2004 · Cited by 367 · see citing works

Mild Experimental Brain Injury in the Rat Induces Cognitive Deficits Associated with Regional Neuronal Loss in the Hippocampus

Hicks, R. R., Smith, D. H., Lowenstein, D. H., Marie, R. L. S., & McIntosh, T. K. (1993) · Journal of Neurotrauma · doi:10.1089/neu.1993.10.405 · Cited by 359 · see citing works

Recovery from brain injury in animals: relative efficacy of environmental enrichment, physical exercise or formal training (1990–2002)

Will, B. E., Galani, R., Kelche, C. R., & Rosenzweig, M. R. (2004) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2004.03.001 · Cited by 349 · see citing works

Evaluation of Memory Dysfunction Following Experimental Brain Injury Using the Morris Water Maze

Smith, D. H., Okiyama, K., Thomas, M. J., CLAUSSEN, B., & McINTOSH, T. K. (1991) · Journal of Neurotrauma · doi:10.1089/neu.1991.8.259 · Cited by 346 · see citing works

Environmental Enrichment Modifies the PKA-Dependence of Hippocampal LTP and Improves Hippocampus-Dependent MemoryPreprint

Duffy, S. N., Craddock, K. J., Abel, T. G., & Nguyen, P. (2001) · Learning & Memory · doi:10.1101/lm.36301 · Cited by 342 · see citing works

Assessment of Lifetime Participation in Cognitively Stimulating Activities

Wilson, R. S., Barnes, L. L., & Bennett, D. A. (2003) · Journal of Clinical and Experimental Neuropsychology · doi:10.1076/jcen.25.5.634.14572 · Cited by 337 · see citing works

Differential effects of enrichment on learning and memory function in NR2B transgenic mice

Tang, Y., Wang, H., Feng, R., Kyin, M., & Tsien, J. Z. (2001) · Neuropharmacology · doi:10.1016/s0028-3908(01)00122-8 · Cited by 330 · see citing works

Nurturing brain plasticity: Impact of environmental enrichment

Baroncelli, L., Braschi, C., Spolidoro, M., Begenisic, T., Sale, A., & Maffei, L. (2010) · Cell Death & Differentiation · doi:10.1038/cdd.2009.193 · Cited by 330 · see citing works

Homeostatic Regulation of Eye-Specific Responses in Visual Cortex during Ocular Dominance Plasticity

Mrsic-Flogel, T. D., Hofer, S. B., Ohki, K., Reid, R. C., Bonhoeffer, T., & Hübener, M. (2007) · Neuron · doi:10.1016/j.neuron.2007.05.028 · Cited by 330 · see citing works

Recent advances in neurotrauma

Graham, D. I., McIntosh, T. K., Maxwell, W. L., & Nicoll, J. A. R. (2000) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/59.8.641 · Cited by 328 · see citing works

Environmental enrichment slows disease progression in R6/2 Huntington's disease mice

Hockly, E., Cordery, P., Woodman, B., Mahal, A., van Dellen, A., Blakemore, C., Lewis, C., Hannan, A., & Bates, G. (2002) · Annals of Neurology · doi:10.1002/ana.10094 · Cited by 326 · see citing works

Evaluation of Attention Process Training and Brain Injury Education in Persons with Acquired Brain Injury

Sohlberg, M. M., McLaughlin, K. A., Pavese, A., Heidrich, A., & Posner, M. I. (2000) · Journal of Clinical and Experimental Neuropsychology · doi:10.1076/1380-3395(200010)22:5;1-9;ft656 · Cited by 326 · see citing works

Environment Influences Functional Outcome of Cerebral Infarction in Rats

Ohlsson, A.-L., & Johansson, B. B. (1995) · Stroke · doi:10.1161/01.str.26.4.644 · Cited by 324 · see citing works

Reducing Intracortical Inhibition in the Adult Visual Cortex Promotes Ocular Dominance Plasticity

Harauzov, A., Spolidoro, M., DiCristo, G., De Pasquale, R., Cancedda, L., Pizzorusso, T., Viegi, A., Berardi, N., & Maffei, L. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.2233-09.2010 · Cited by 319 · see citing works

Environment, Social Interaction, and Physical Activity as Determinants of Functional Outcome after Cerebral Infarction in the Rat

Johansson, B. B., & Ohlsson, A.-L. (1996) · Experimental Neurology · doi:10.1006/exnr.1996.0106 · Cited by 311 · see citing works

Experience-dependent plasticity in adult rat barrel cortex.

Diamond, M. E., Armstrong‐James, M., & Ebner, F. F. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.5.2082 · Cited by 309 · see citing works

Motor Enrichment and the Induction of Plasticity Before or After Brain Injury

Kleim, J. A., Jones, T. A., & Schallert, T. J. (2003) · Neurochemical Research · doi:10.1023/a:1026025408742 · Cited by 309 · see citing works

Enrichment enhances spatial memory and increases synaptophysin levels in aged female mice

Frick, K. M., & Fernandez, S. M. (2003) · Neurobiology of Aging · doi:10.1016/s0197-4580(02)00138-0 · Cited by 303 · see citing works

Traumatic brain injury: Can the consequences be stopped?

Park, E., Bell, J. D., & BAKER, A. J. (2008) · Canadian Medical Association Journal · doi:10.1503/cmaj.080282 · Cited by 300 · see citing works

The impairments in reaching and the movements of compensation in rats with motor cortex lesions: an endpoint, videorecording, and movement notation analysis

Whishaw, I. Q., Pellis, S. M., Gorny, B. P., & Pellis, V. C. (1991) · Behavioural Brain Research · doi:10.1016/s0166-4328(05)80042-7 · Cited by 296 · see citing works

Dissociable effects of isolation rearing and environmental enrichment on exploration, spatial learning and HPA activity in adult rats

Schrijver, N. C. A., Bahr, N. I., Weiss, I. C., & Würbel, H. (2002) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(02)00790-6 · Cited by 294 · see citing works

Laminar Comparison of Somatosensory Cortical Plasticity

Diamond, M. E., Huang, W. M., & Ebner, F. F. (1994) · Science · doi:10.1126/science.8091215 · Cited by 289 · see citing works

Environmental enrichment and the brain

Mohammed, A. H., Zhu, S., Darmopil, S., Hjerling‐Leffler, J., Ernfors, P., Winblad, B. G., Diamond, M. C., Eriksson, P. S., & Bogdanović, N. (2002) · Progress in brain research · doi:10.1016/s0079-6123(02)38074-9 · Cited by 267 · see citing works

Excitatory-inhibitory balance and critical period plasticity in developing visual cortex

Hensch, T. K., & Fagiolini, M. (2005) · Progress in Brain Research · doi:10.1016/s0079-6123(04)47009-5 · Cited by 267 · see citing works

Community based rehabilitation after severe traumatic brain injury: a randomised controlled trial

Powell, J. E. (2002) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.72.2.193 · Cited by 263 · see citing works

Changes in brain nerve growth factor levels and nerve growth factor receptors in rats exposed to environmental enrichment for one year

Pham, T. M., Ickes, B. R., Albeck, D. S., Söderström, S., Granholm, A.-C., & Mohammed, A. H. (1999) · Neuroscience · doi:10.1016/s0306-4522(99)00316-4 · Cited by 262 · see citing works

Assessment of lifetime participation in cognitively stimulating activities

Wilson, R. S., Barnes, L. L., & Bennett, D. A. (2013) · Psychology Press eBooks · doi:10.4324/9780203783047-18 · Cited by 262 · see citing works

Extensive cortical depth measurements and neuron size increases in the cortex of environmentally enriched rats

Diamond, M. C., Lindner, B., & Raymond, A. (1967) · Journal of Comparative Neurology · doi:10.1002/cne.901310305 · Cited by 260 · see citing works

Neuronal Plasticity and Dendritic Spines: Effect of Environmental Enrichment on Intact and Postischemic Rat Brain

Johansson, B. B., & Belichenko, P. V. (2002) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/00004647-200201000-00011 · Cited by 253 · see citing works

Long‐lasting modulation of the induction of LTD and LTP in rat hippocampal CA1 by behavioural stress and environmental enrichment

Artola, A., von Frijtag, J. C., Fermont, P. C. J., Gispen, W. H., Schrama, L. H., Kamal, A., & Spruijt, B. M. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.04552.x · Cited by 253 · see citing works

Changes in the sensory processing of olfactory signals induced by birth in sleep

Kendrick, K., Levy, F., & Keverne, E. (1992) · Science · doi:10.1126/science.1589766 · Cited by 244 · see citing works

Effectiveness of attention rehabilitation after an acquired brain injury: A meta-analysis.

Park, N. W., & Ingles, J. L. (2001) · Neuropsychology · doi:10.1037/0894-4105.15.2.199 · Cited by 243 · see citing works

A detailed analysis of open-field habituation and behavioral and neurochemical antidepressant-like effects in postweaning enriched rats.

Brenes, J. C., Padilla, M., & Fornaguera, J. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2008.08.014 · Cited by 242 · see citing works

Environmental enrichment in adulthood eliminates neuronal death in experimental Parkinsonism

Faherty, C. J., Shepherd, K. R., Herasimtschuk, A., & Smeyne, R. J. (2004) · Molecular Brain Research · doi:10.1016/j.molbrainres.2004.08.008 · Cited by 241 · see citing works

Environmental Enrichment Exacerbates Amyloid Plaque Formation in a Transgenic Mouse Model of Alzheimer Disease

Jankowsky, J. L., Xu, G. M., Fromholt, D., Gonzales, V., & Borchelt, D. (2003) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/62.12.1220 · Cited by 240 · see citing works

Modification of hippocampal neurogenesis and neuroplasticity by social environments

Lü, L., Bao, G., Chen, H., Xia, P., Fan, X., Zhang, J., Pei, G., & Ma, L. (2003) · Experimental Neurology · doi:10.1016/s0014-4886(03)00248-6 · Cited by 238 · see citing works

Synaptic plasticity in cortical systems

Klintsova, A. Y., & Greenough, W. T. (1999) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(99)80028-2 · Cited by 237 · see citing works

Environmental enrichment improves cognition in aged Alzheimer's transgenic mice despite stable β-amyloid deposition

Arendash, G. W., Garcia, M. F., Costa, D. A., Cracchiolo, J. R., Wefes, I., & Potter, H. (2004) · Neuroreport · doi:10.1097/01.wnr.0000137183.68847.4e · Cited by 237 · see citing works

Improvement in perceptual judgments as a function of controlled practice or training.

Gibson, E. J. (1953) · Psychological Bulletin · doi:10.1037/h0055517 · Cited by 234 · see citing works

Thalamic integrity underlies executive dysfunction in traumatic brain injury

Little, D. M., Kraus, M. F., Joseph, J. W., Geary, E., Susmaras, T. M., Zhou, X. J., Pliskin, N. H., & Gorelick, P. B. (2010) · Neurology · doi:10.1212/wnl.0b013e3181cff5d5 · Cited by 234 · see citing works

Neural Plasticity: The Biological Substrate For Neurorehabilitation

Warraich, Z., & Kleim, J. A. (2010) · PM&R · doi:10.1016/j.pmrj.2010.10.016 · Cited by 227 · see citing works

Community integration and satisfaction with functioning after intensive cognitive rehabilitation for traumatic brain injury11No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit on the author(s) or on any organization with which the author(s) is/are associated.

Cicerone, K. D., Mott, T., Azulay, J., & Friel, J. C. (2004) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2003.07.019 · Cited by 227 · see citing works

Enrichment-dependent differences in novelty exploration in rats can be explained by habituation.

Zimmermann, A., Stauffacher, M., Langhans, W., & Würbel, H. (2001) · Behavioural Brain Research · doi:10.1016/s0166-4328(00)00377-6 · Cited by 221 · see citing works

Effects of differential environments on plasticity of dendrites of cortical pyramidal neurons in adult rats

Uylings, H. B. M., Kuypers, K., Diamond, M. C., & Veltman, W. A. M. (1978) · Experimental Neurology · doi:10.1016/0014-4886(78)90276-5 · Cited by 219 · see citing works

Dendritic branching: some preliminary results of training and complexity in rat visual cortex

Holloway, R. L. (1966) · Brain Research · doi:10.1016/0006-8993(66)90009-6 · Cited by 215 · see citing works

Environmental enrichment and isolation rearing in the rat: effects on locomotor behavior and startle response plasticity

Varty, G. B., Paulus, M. P., BRAFF, D. L., & Geyer, M. A. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00269-3 · Cited by 211 · see citing works

Effects of environmental enrichment and impoverishment on rat cerebral cortex

Diamond, M. C., Rosenzweig, M. R., Bennett, E. L., Lindner, B., & Lyon, L. (1972) · Journal of Neurobiology · doi:10.1002/neu.480030105 · Cited by 211 · see citing works

Enriched Environment Confers Resistance to 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine and Cocaine: Involvement of Dopamine Transporter and Trophic Factors

Bézard, E., Doveró, S., Belin, D., Duconger, S., Jackson-Lewis, V. R., Przedborski, S., Piazza, P. V., Gross, C. E., & Jaber, M. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-35-10999.2003 · Cited by 209 · see citing works

Naturalistic experience transforms sensory maps in the adult cortex of caged animals

Polley, D. B., Kvašňák, E., & Frostig, R. D. (2004) · Nature · doi:10.1038/nature02469 · Cited by 205 · see citing works

Psychological stress and environmental adaptation in enriched vs. impoverished housed rats

Larsson, F., Winblad, B. G., & Mohammed, A. H. S. (2002) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(02)00782-7 · Cited by 205 · see citing works

Therapeutic Effects of Environmental Enrichment on Cognitive Function and Tissue Integrity Following Severe Traumatic Brain Injury in Rats

Passineau, M. J., Green, E. J., & Dietrich, W. D. (2001) · Experimental Neurology · doi:10.1006/exnr.2000.7623 · Cited by 204 · see citing works

Environmental Enrichment and Cortical Injury: Behavioral and Anatomical Consequences of Frontal Cortex Lesions

Kolb, B. E., & Gibb, R. L. (1991) · Cerebral Cortex · doi:10.1093/cercor/1.2.189 · Cited by 199 · see citing works

Environmental Enrichment Improves Response Strength, Threshold, Selectivity, and Latency of Auditory Cortex Neurons

Engineer, N. D., Percaccio, C. R., Pandya, P. K., Moucha, R., Rathbun, D. L., & Kilgard, M. P. (2004) · Journal of Neurophysiology · doi:10.1152/jn.00059.2004 · Cited by 198 · see citing works

Effects of environment on morphology of rat cerebral cortex and hippocampus

Diamond, M. C., Ingham, C. A., Johnson, R. E., Bennett, E. L., & Rosenzweig, M. R. (1976) · Journal of Neurobiology · doi:10.1002/neu.480070108 · Cited by 192 · see citing works

Environmental enrichment results in cortical and subcortical changes in levels of synaptophysin and PSD-95 proteins

Nithianantharajah, J. (2004) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2004.02.002 · Cited by 191 · see citing works

The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice

Wen, P. H., Hof, P. R., Chen, X., Gluck, K., Austin, G., Younkin, S. G., Younkin, L. H., DeGasperi, R., Sosa, M. A. G., Robakis, N. K. R. K., et al. (2004) · Experimental Neurology · doi:10.1016/j.expneurol.2004.04.002 · Cited by 190 · see citing works

Gene–environment interactions modulating cognitive function and molecular correlates of synaptic plasticity in Huntington’s disease transgenic mice

Nithianantharajah, J., Barkus, C., Murphy, M., & Hannan, A. J. (2007) · Neurobiology of Disease · doi:10.1016/j.nbd.2007.11.006 · Cited by 187 · see citing works

Rat Brain: Effects of Environmental Enrichment on Wet and Dry Weights

Bennett, E. L., Rosenzweig, M. R., & Diamond, M. C. (1969) · Science · doi:10.1126/science.163.3869.825 · Cited by 186 · see citing works

Traumatic brain injury

Risdall, J. E., & Menon, D. K. (2011) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2010.0230 · Cited by 185 · see citing works

Environmental enrichment results in higher levels of nerve growth factor mRNA in the rat visual cortex and hippocampus

Torasdotter, M., METSIS, M. L., Henriksson, B. G., Winblad, B. G., & Mohammed, A. H. S. (1998) · Behavioural Brain Research · doi:10.1016/s0166-4328(97)00142-3 · Cited by 184 · see citing works

Altered synaptic transmission in dentate gyrus of rats reared in complex environments: evidence from hippocampal slices maintained in vitro

Green, E. J., & Greenough, W. T. (1986) · Journal of Neurophysiology · doi:10.1152/jn.1986.55.4.739 · Cited by 180 · see citing works

Intraventricular norepinephrine facilitates motor recovery following sensorimotor cortex injury

Boyeson, M. G., & Feeney, D. M. (1990) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(90)90279-q · Cited by 176 · see citing works

Environmental enrichment promotes neurogenesis and changes the extracellular concentrations of glutamate and GABA in the hippocampus of aged rats

Segovia, G., Yagüe, A. G., García‐Verdugo, J. M., & Mora, F. (2005) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2005.11.005 · Cited by 173 · see citing works

Habituation produces frequency-specific plasticity of receptive fields in the auditory cortex.

Condon, C. D., & Weinberger, N. M. (1991) · Behavioral Neuroscience · doi:10.1037//0735-7044.105.3.416 · Cited by 173 · see citing works

Neural circuit mechanisms of post–traumatic epilepsy

Hunt, R. F., Boychuk, J. A., & Smith, B. N. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00089 · Cited by 173 · see citing works

Neurogenesis in the R6/1 transgenic mouse model of Huntington's disease: effects of environmental enrichment

Lazic, S. E., Grote, H., Blakemore, C. B., Hannan, A. J., van Dellen, A., Phillips, W., & Barker, R. A. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.04715.x · Cited by 172 · see citing works

Early-life handling stimulation and environmental enrichment

Fernández-Teruel, A., Giménez-Llort, L., Escorihuela, R. M., Gil, L., Aguilar, R., Steimer, T., & Tobeña, A. (2002) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(02)00787-6 · Cited by 171 · see citing works

Development of spectral and temporal response selectivity in the auditory cortex

Chang, E. F., Bao, S., Imaizumi, K., Schreiner, C. E., & Merzenich, M. M. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0508239102 · Cited by 171 · see citing works

Impact of enriched-environment housing on brain-derived neurotrophic factor and on cognitive performance after a transient global ischemia

Gobbo, O. L., & O’Mara, S. M. (2003) · Behavioural Brain Research · doi:10.1016/j.bbr.2003.10.017 · Cited by 170 · see citing works

Complex environment experience rescues impaired neurogenesis, enhances synaptic plasticity, and attenuates neuropathology in familial Alzheimer's disease‐linked APPswe/PS1ΔE9 mice

Hu, Y., Xu, P., Pigino, G. F., Brady, S. T., Larson, J., & Lazarov, O. (2010) · The FASEB Journal · doi:10.1096/fj.09-136945 · Cited by 168 · see citing works

Exposure to Environmental Complexity Promotes Recovery of Cognitive Function after Traumatic Brain Injury

Hamm, R. J., Temple, M. D., O’Dell, D. M., PIKE, B. R., & Lyeth, B. G. (1996) · Journal of Neurotrauma · doi:10.1089/neu.1996.13.41 · Cited by 168 · see citing works

Relatively brief environmental enrichment aids recovery of learning capacity and alters brain measures after postweaning brain lesions in rats.

Will, B. E., Rosenzweig, M. R., Bennett, E. L., Hébert, M., & Morimoto, H. (1977) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0077306 · Cited by 165 · see citing works

Short‐term environmental enrichment, in the absence of exercise, improves memory, and increases NGF concentration, early neuronal survival, and synaptogenesis in the dentate gyrus in a time‐dependent manner

Birch, A. M., McGarry, N., & Kelly, A. M. (2013) · Hippocampus · doi:10.1002/hipo.22103 · Cited by 161 · see citing works

Enhanced cognitive activity--over and above social or physical activity--is required to protect Alzheimer's mice against cognitive impairment, reduce Abeta deposition, and increase synaptic immunoreactivity.

Cracchiolo, J. R., Mori, T., Nazian, S., Tan, J., Potter, H., & Arendash, G. (2007) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2007.07.007 · Cited by 161 · see citing works

Brain Plasticity and Disease: A Matter of Inhibition

Baroncelli, L., Braschi, C., Spolidoro, M., Begenisic, T., Maffei, L., & Sale, A. (2011) · Neural Plasticity · doi:10.1155/2011/286073 · Cited by 160 · see citing works

Effects of social and physical enrichment on open field activity differ in male and female Sprague–Dawley rats

ELLIOTT, B., & Grunberg, N. E. (2005) · Behavioural Brain Research · doi:10.1016/j.bbr.2005.06.025 · Cited by 159 · see citing works

The effects of environmental complexity on the histology of the rat hippocampus

WALSH, R. N., Budtz‐Olsen, O. E., Penny, J. E., & Cummins, R. A. (1969) · The Journal of Comparative Neurology · doi:10.1002/cne.901370309 · Cited by 158 · see citing works

General Lifestyle Activities as a Predictor of Current Cognition and Cognitive Change in Older Adults: A Cross-Sectional and Longitudinal Examination

Newson, R. S., & Kemps, E. (2005) · The Journals of Gerontology Series B · doi:10.1093/geronb/60.3.p113 · Cited by 157 · see citing works

Spectrally enhanced acoustic environment disrupts frequency representation in cat auditory cortex

Noreña, A. J., Gourévitch, B., Aizawa, N., & Eggermont, J. J. (2006) · Nature Neuroscience · doi:10.1038/nn1720 · Cited by 146 · see citing works

Neuroprotective effects of cognitive enrichment

Milgram, N. W., Siwak-Tapp, C. T., Araujo, J., & Head, E. (2006) · Ageing Research Reviews · doi:10.1016/j.arr.2006.04.004 · Cited by 146 · see citing works

ApoE4 impairs hippocampal plasticity isoform-specifically and blocks the environmental stimulation of synaptogenesis and memory

Levi, O., Jongen‐Rêlo, A. L., Feldon, J., Roses, A. D., & Michaelson, D. M. (2003) · Neurobiology of Disease · doi:10.1016/s0969-9961(03)00045-7 · Cited by 145 · see citing works

Experience-dependent reactivation of ocular dominance plasticity in the adult visual cortex

Baroncelli, L., Sale, A., Viegi, A., Maya‐Vetencourt, J. F., Pasquale, R. D., Baldini, S., & Maffei, L. (2010) · Experimental Neurology · doi:10.1016/j.expneurol.2010.08.009 · Cited by 145 · see citing works

Enhancement of hippocampal field potentials in rats exposed to a novel, complex environment

Sharp, P. E., McNaughton, B. L., & Barnes, C. A. (1985) · Brain Research · doi:10.1016/0006-8993(85)90105-2 · Cited by 144 · see citing works

Habituation produces frequency-specific plasticity of receptive fields in the auditory cortex.

Condon, C. D., & Weinberger, N. M. (1991) · Behavioral Neuroscience · doi:10.1037/0735-7044.105.3.416 · Cited by 143 · see citing works

Experience-induced plasticity of cutaneous maps in the primary somatosensory cortex of adult monkeys and rats

Xerri, C., Coq, J., Merzenich, M. M., et al. (1996) · Journal of Physiology-Paris · doi:10.1016/s0928-4257(97)81438-6 · Cited by 142 · see citing works

Alterations in BDNF and NT-3 mRNAs in rat hippocampus after experimental brain trauma

Hicks, R. R., Numan, S., Dhillon, H. S., Prasad, M. R., & Seroogy, K. B. (1997) · Molecular Brain Research · doi:10.1016/s0169-328x(97)00158-7 · Cited by 141 · see citing works

Environmental enrichment reverses learning impairment in the Morris water maze after focal cerebral ischemia in rats

Dahlqvist, P. M., Rönnbäck, A., Bergström, S., Söderström, I., & Olsson, T. (2004) · European Journal of Neuroscience · doi:10.1111/j.0953-816x.2004.03248.x · Cited by 140 · see citing works

Can structural or functional changes following traumatic brain injury in the rat predict epileptic outcome?

Shultz, S. R., Cardamone, L., Liu, Y. R., Hogan, R. E., Maccotta, L., Wright, D. K., Zheng, P., Koe, A. S., Grégoire, M., Williams, J. P., et al. (2013) · Epilepsia · doi:10.1111/epi.12223 · Cited by 139 · see citing works

Beneficial effects of enriched environment following status epilepticus in immature rats

Faverjon, S., Silveira, D. C., Fu, D., Cha, B. H., Akman, Ç. I., Hu, Y., & Holmes, G. L. (2002) · Neurology · doi:10.1212/01.wnl.0000033588.59005.55 · Cited by 136 · see citing works

Postrecovery Cognitive Decline in Adults With Traumatic Brain Injury

Till, C., Colella, B., Verwegen, J., & Green, R. (2008) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2008.07.004 · Cited by 136 · see citing works

A multicontext approach to promoting transfer of strategy use and self regulation after brain injury: An exploratory study

Toglia, J. P., Johnston, M. V., Goverover, Y., & Dain, B. (2010) · Brain Injury · doi:10.3109/02699051003610474 · Cited by 136 · see citing works

Environmental influences on functional outcome after a cortical infarct in the rat

Risedal, A., Mattsson, B., Dahlqvist, P. M., Nordborg, C., Olsson, T., & Johansson, B. B. (2002) · Brain Research Bulletin · doi:10.1016/s0361-9230(02)00796-7 · Cited by 136 · see citing works

Induction of Multiple Synapses by Experience in the Visual Cortex of Adult Rats

Jones, T. A., Klintsova, A. Y., Kilman, V. L., Sirevaag, A. M., & Greenough, W. T. (1997) · Neurobiology of Learning and Memory · doi:10.1006/nlme.1997.3774 · Cited by 134 · see citing works

Environmental enrichment selectively increases 5-HT1A receptor mRNA expression and binding in the rat hippocampus

Rasmuson, S., Olsson, T., Henriksson, B. G., Kelly, P. A. T., Holmes, M. C., Seckl, J. R., & Mohammed, A. H. S. (1998) · Molecular Brain Research · doi:10.1016/s0169-328x(97)00317-3 · Cited by 134 · see citing works

Exercise improves object recognition memory and induces BDNF expression and cell proliferation in cognitively enriched rats

Bechara, R. G., & Kelly, A. M. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.02.018 · Cited by 132 · see citing works

Mechanism of altered synaptic strength due to experience: relation to long-term potentiation.

Foster, T. C., Gagné, J., & Massicotte, G. (1996) · Brain Research · doi:10.1016/0006-8993(96)00707-x · Cited by 131 · see citing works

Effects of cognitive enrichment on behavioural and physiological reactions of pigs

Zebunke, M., Puppe, B., & Langbein, J. (2013) · Physiology & Behavior · doi:10.1016/j.physbeh.2013.05.005 · Cited by 130 · see citing works

Effects of daily environmental enrichment on memory deficits and brain injury following neonatal hypoxia-ischemia in the rat

Pereira, L. O., Arteni, N. S., Petersen, R. C., da Rocha, A. P., Achaval, M., & Netto, C. A. (2006) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2006.07.003 · Cited by 129 · see citing works

Generalization of Treatment: A Multicontext Approach to Cognitive Perceptual Impairment in Adults With Brain Injury

Toglia, J. P. (1991) · American Journal of Occupational Therapy · doi:10.5014/ajot.45.6.505 · Cited by 128 · see citing works

Environmental enrichment alters organizational features of the forepaw representation in the primary somatosensory cortex of adult rats

Coq, J., & Xerri, C. (1998) · Experimental Brain Research · doi:10.1007/s002210050452 · Cited by 128 · see citing works

A randomised controlled trial to determine the effect of intensity of therapy upon length of stay in a neurological rehabilitation setting

Slade, A. L., Tennant, A. H., & Chamberlain, M. A. (2002) · Journal of Rehabilitation Medicine · doi:10.1080/165019702760390347 · Cited by 122 · see citing works

Does intensive rehabilitation improve the functional outcome of patients with traumatic brain injury (TBI)? A randomized controlled trial

Zhu, X. L., Poon, W. S., Chan, C. C. H., & Chan, S. S. H. (2007) · Brain Injury · doi:10.1080/02699050701468941 · Cited by 120 · see citing works

Enriched environment after focal cortical ischemia enhances the generation of astroglia and NG2 positive polydendrocytes in adult rat neocortex

Komitova, M., Perfilieva, E., Mattsson, B., Eriksson, P. S., & Johansson, B. B. (2006) · Experimental Neurology · doi:10.1016/j.expneurol.2005.12.007 · Cited by 120 · see citing works

Learning-Induced Survival of New Neurons Depends on the Cognitive Status of Aged Rats

Drapeau, E., Montaron, M., Aguerre, S., & Abrous, D. N. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.1031-07.2007 · Cited by 119 · see citing works

Enriched experience and recovery from amblyopia in adult rats: Impact of motor, social and sensory components

Baroncelli, L., Bonaccorsi, J., Milanese, M., Bonifacino, T., Giribaldi, F., Manno, I., Cenni, M. C., Berardi, N., Bonanno, G., Maffei, L., et al. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.02.010 · Cited by 117 · see citing works

Memory impairment following status epilepticus in immature rats: time‐course and environmental effects

Rutten, A., van Albada, M. E., Silveira, D. C., Cha, B. H., Liu, X., Hu, Y. N., Cilio, M. R., & Holmes, G. L. (2002) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2002.02103.x · Cited by 116 · see citing works

Long-term, partially-reversible reorganization of frequency tuning in mature cat primary auditory cortex can be induced by passive exposure to moderate-level sounds

Pienkowski, M., & Eggermont, J. J. (2009) · Hearing Research · doi:10.1016/j.heares.2009.07.011 · Cited by 116 · see citing works

Environmental enrichment improves functional and neuropathological indices following stroke in young and aged rats

Buchhold, B., Mogoantă, L., Suofu, Y., Hamm, A. O., Walker, L. C., Kessler, C., & Popa‐Wagner, A. (2007) · Restorative Neurology and Neuroscience · doi:10.3233/rnn-2007-00404 · Cited by 115 · see citing works

The effects of increased rehabilitation therapy after brain injury: results of a prospective controlled trial

Shiel, A., Burn, J. P., Henry, D. A., Clark, J., Wilson, B. A., Burnett, M., & McLellan, D. L. (2001) · Clinical Rehabilitation · doi:10.1191/026921501680425225 · Cited by 115 · see citing works

Effects of daily environmental enrichment on behavior and dendritic spine density in hippocampus following neonatal hypoxia–ischemia in the rat

Rojas, J. J., Deniz, B. F., Miguel, P. M., Diaz, R., Hermel, É. D. E. S., Achaval, M., Netto, C. A., & Pereira, L. O. (2012) · Experimental Neurology · doi:10.1016/j.expneurol.2012.11.026 · Cited by 114 · see citing works

Natural Restoration of Critical Period Plasticity in the Juvenile and Adult Primary Auditory Cortex

Zhou, X., Panizzutti, R., de Villers‐Sidani, E., Madeira, C., & Merzenich, M. M. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.6470-10.2011 · Cited by 114 · see citing works

Animal Models of Post-Traumatic Epilepsy

Pitkänen, A., & McIntosh, T. (2006) · Journal of Neurotrauma · doi:10.1089/neu.2006.23.241 · Cited by 112 · see citing works

Mechanism for increased hippocampal synaptic strength following differential experience.

Foster, T. C., & Dumas, T. C. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.85.4.1377 · Cited by 111 · see citing works

Environmental Enrichment Delays the Onset of Memory Deficits and Reduces Neuropathological Hallmarks in a Mouse Model of Alzheimer-Like Neurodegeneration

Berardi, N., Braschi, C., Capsoni, S., Cattaneo, A., & Maffei, L. (2007) · Journal of Alzheimer s Disease · doi:10.3233/jad-2007-11312 · Cited by 110 · see citing works

Lifelong plasticity in the rat auditory cortex

de Villers‐Sidani, E., & Merzenich, M. M. (2011) · Progress in brain research · doi:10.1016/b978-0-444-53752-2.00009-6 · Cited by 110 · see citing works

Olfactory Bulb Mitral-Tufted Cell Plasticity: Odorant-Specific Tuning Reflects Previous Odorant Exposure

Fletcher, M. L., & Wilson, D. A. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-17-06946.2003 · Cited by 110 · see citing works

Speeded performance following head injury in children

Bawden, H. N., Knights, R. M., & Winogron, H. W. (1985) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/01688638508401241 · Cited by 107 · see citing works

Empirical Comparison of Typical and Atypical Environmental Enrichment Paradigms on Functional and Histological Outcome after Experimental Traumatic Brain Injury

Sozda, C. N., Hoffman, A. N., Olsen, A. S., B, J. P. C. A., ZAFONTE, R. D., & Kline, A. E. (2010) · Journal of Neurotrauma · doi:10.1089/neu.2010.1313 · Cited by 107 · see citing works

Acute treatment with the 5-HT1A receptor agonist 8-OH-DPAT and chronic environmental enrichment confer neurobehavioral benefit after experimental brain trauma

Kline, A. E., Wagner, A., Westergom, B. P., Malena, R. R., ZAFONTE, R. D., Olsen, A. S., Sozda, C. N., Luthra, P., Panda, M., & B, J. P. C. A. (2006) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.11.036 · Cited by 107 · see citing works

Effects of Enriched Environment and Fluid Percussion Injury on Dendritic Arborization within the Cerebral Cortex of the Developing Rat

Ip, E. Y.-Y., Giza, C. C., Griesbach, G. S., & Hovda, D. A. (2002) · Journal of Neurotrauma · doi:10.1089/089771502753754055 · Cited by 105 · see citing works

Structural Dynamics of Dendritic Spines are Influenced by an Environmental Enrichment: An In Vivo Imaging Study

Jung, C. K. E., & Herms, J. W. (2012) · Cerebral Cortex · doi:10.1093/cercor/bhs317 · Cited by 105 · see citing works

Intervention with environmental enrichment after experimental brain trauma enhances cognitive recovery in male but not female rats

Wagner, A. K., Kline, A. E., Sokoloski, J. E., ZAFONTE, R. D., Capulong, E., & Dixon, C. E. (2002) · Neuroscience Letters · doi:10.1016/s0304-3940(02)01103-5 · Cited by 104 · see citing works

Cortical Excitation and Inhibition Following Focal Traumatic Brain Injury

Ding, M., Wang, Q., Lo, E. H., & Stanley, G. B. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.3572-11.2011 · Cited by 103 · see citing works

Basic Fibroblast Growth Factor Selectively Increases AMPA‐Receptor Subunit GluR1 Protein Level and Differentially Modulates Ca2+ Responses to AMPA and NMDA in Hippocampal Neurons

Cheng, B., Furukawa, K., O'Keefe, J. A., Goodman, Y., Kihiko, M., Fabian, T., & Mattson, M. P. (1995) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1995.65062525.x · Cited by 101 · see citing works

Environmental Enrichment as a Viable Neurorehabilitation Strategy for Experimental Traumatic Brain Injury

Bondi, C. O., Klitsch, K. C., Leary, J. B., & Kline, A. E. (2014) · Journal of Neurotrauma · doi:10.1089/neu.2014.3328 · Cited by 101 · see citing works

Depressive behavior and selective downregulation of serotonin receptor expression after early-life seizures: Reversal by environmental enrichment

Koh, S., Magid, R., Chung, H., Stine, C. D., & Wilson, D. N. (2006) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2006.11.008 · Cited by 101 · see citing works

Short-Term Environmental Enrichment Rescues Adult Neurogenesis and Memory Deficits in APPSw,Ind Transgenic Mice

Valero, J., España, J., Parra‐Damas, A., Martín, E., Rodrı́guez-Álvarez, J., & Saura, C. A. (2011) · PLoS ONE · doi:10.1371/journal.pone.0016832 · Cited by 100 · see citing works

Effect of the richness of the environment on the cat visual cortex

Beaulieu, C., & Colonnier, M. (1987) · The Journal of Comparative Neurology · doi:10.1002/cne.902660404 · Cited by 99 · see citing works

Delayed kindling epileptogenesis and increased neurogenesis in adult rats housed in an enriched environment

Auvergne, R., Leré, C., El Bahh, B., Arthaud, S., Lespinet, V., Rougier, A., & Le Gal La Salle, G. (2002) · Brain Research · doi:10.1016/s0006-8993(02)03355-3 · Cited by 98 · see citing works

Evaluation of Social and Physical Enrichment in Modulation of Behavioural Phenotype in C57BL/6J Female Mice

Kulesskaya, N., Rauvala, H., & Võikar, V. (2011) · PLoS ONE · doi:10.1371/journal.pone.0024755 · Cited by 98 · see citing works

Progressive Degradation and Subsequent Refinement of Acoustic Representations in the Adult Auditory Cortex

Bao, S., Chang, E. F., Davis, J. D., Gobeske, K. T., & Merzenich, M. M. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-34-10765.2003 · Cited by 96 · see citing works

Differential activation of the rat hippocampus and perirhinal cortex by novel visual stimuli and a novel environment

Zhu, X. O., McCabe, B. J., Aggleton, J. P., & Brown, M. W. (1997) · Neuroscience Letters · doi:10.1016/s0304-3940(97)00437-0 · Cited by 95 · see citing works

Enriched environment improves motor function in intact and unilateral dopamine-depleted rats

Jadavji, N. M., Kolb, B. E., & Metz, G. A. S. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.03.027 · Cited by 94 · see citing works

Environmental enrichment stimulates neurogenesis in apolipoprotein E3 and neuronal apoptosis in apolipoprotein E4 transgenic mice

Levi, O., & Michaelson, D. M. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.04189.x · Cited by 94 · see citing works

Ipsilesional neglect: behavioural and anatomical features

Kim, M. K., Na, D. L., Kim, G. M., et al. (1999) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.67.1.35 · Cited by 93 · see citing works

Environmental enrichment attenuates cognitive deficits, but does not alter neurotrophin gene expression in the hippocampus following lateral fluid percussion brain injury.

Hicks, R., Zhang, L.-P., Atkinson, A., Stevenon, M., Veneracion, M., & Seroogy, K. (2002) · Neuroscience · doi:10.1016/s0306-4522(02)00104-5 · Cited by 92 · see citing works

Enrichment to odors improves olfactory discrimination in adult rats.

Mandairon, N., Stack, C. M., Kiselycznyk, C., & Linster, C. (2006) · Behavioral Neuroscience · doi:10.1037/0735-7044.120.1.173 · Cited by 92 · see citing works

The applied implications of epigenetics in anxiety, affective and stress-related disorders - A review and synthesis on psychosocial stress, psychotherapy and prevention

Schiele, M. A., Gottschalk, M. G., & Domschke, K. (2020) · Clinical Psychology Review · doi:10.1016/j.cpr.2020.101830 · Cited by 156 · see citing works

Environmental stimulation improves functional deficits induced by hypoxic-ischemic brain damage in neonatal rats

Yun, C. (2001) · Chinexe Journal of Pediatrics

Effects of enriched environment and impoverished environment on brain function of premature rats after hypoxic-ischemic brain damage

Songmei, L. (2009) · Di-san junyi daxue xuebao

The brain and its activity

Christe, B. L. (2009) · Cambridge University Press eBooks · doi:10.1017/cbo9780511808937.011 · Cited by 1 · see citing works

A primer for brain imaging: a tool for evidence-based studies of nutrition?

Paus, T. (2010) · Nutrition Reviews · doi:10.1111/j.1753-4887.2010.00327.x · Cited by 15 · see citing works

Recovery from brain damage. Reflections and directions. European Brain and Behaviour Society's Workshop on Recovery of Function Following Brain Damage. London, April 1991. Invited review lectures.

(1992) · PubMed