Altered network hub connectivity after acute LSD administration
Open accessAbstract
LSD is an ambiguous substance, said to mimic psychosis and to improve mental health in people suffering from anxiety and depression. Little is known about the neuronal correlates of altered states of consciousness induced by this substance. Limited previous studies indicated profound changes in functional connectivity of resting state networks after the administration of LSD. The current investigation attempts to replicate and extend those findings in an independent sample. In a double-blind, randomized, cross-over study, 100 μg LSD and placebo were orally administered to 20 healthy participants. Resting state brain activity was assessed by functional magnetic resonance imaging. Within -network and between -network connectivity measures of ten established resting state networks were compared between drug conditions. Complementary analysis were conducted using resting state networks as sources in seed-to-voxel analyses. Acute LSD administration significantly decreased functional connectivity within visual, sensorimotor and auditory networks and the default mode network. While between -network connectivity was widely increased and all investigated networks were affected to some extent, seed-to-voxel analyses consistently indicated increased connectivity between networks and subcortical (thalamus, striatum) and cortical (precuneus, anterior cingulate cortex) hub structures. These latter observations are consistent with findings on the importance of hubs in psychopathological states, especially in psychosis, and could underlay therapeutic effects of hallucinogens as proposed by a recent model.
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During psychedelic experience, fMRI shows the default mode network is modulated, sharply reducing blood flow and connection within its nodes, leading to decreased functional connectivity within the DMN and increased between-network connectivity.
“It has been demonstrated with functional magnetic resonance imaging (fMRI) that during psychedelic experience, the DMN is modulated, which sharply reduces blood flow and connection within its nodes [46], leading to decreased functional connectivity within the DMN and increased between-network connectivity [47, 48].”
From Mindfulness meditation and psychedelics: potential synergies and commonalities (2023) · cites this paper as [48]
The Results (Within-network connectivity; page unavailable) report decreased coactivation in the medial-posterior DMN under LSD, and the Results (Between-network connectivity; page unavailable) report widespread increases in connectivity between networks. The paper does not report a sharp reduction in blood flow within DMN nodes or establish that such a reduction led to the connectivity changes. (LLM, conf=0.87)
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Cites
A default mode of brain function
Raichle, M. E., MacLeod, A. M., Snyder, A. Z., Powers, W. J., Gusnard, D. A., & Shulman, G. L. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.2.676 · Cited by 12,190 · see citing works
<i>The Brain's Default Network</i>: <i>Anatomy, Function, and Relevance to Disease</i>
Buckner, R. L., Andrews‐Hanna, J. R., & Schacter, D. L. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1440.011 · Cited by 9,761 · cited 1× · see citing works
“The DMN is particularly activated during rest and is thought to be involved in functions such as self-referential thinking (Buckner et al., 2008; Raichle et al., 2001).”
BackgroundParallel organization of functionally segregated circuits linking basal ganglia and cortex
Alexander, G. E., DeLong, M. R., & Strick, P. L. (1986) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.09.030186.002041 · Cited by 8,527 · see citing works
The organization of the human cerebellum estimated by intrinsic functional connectivity
Buckner, R. L., Krienen, F. M., Castellanos, A., Diaz, J. C., & Yeo, B. T. T. (2011) · Journal of Neurophysiology · doi:10.1152/jn.00339.2011 · Cited by 7,304 · see citing works
Correspondence of the brain's functional architecture during activation and rest
Smith, S. M., Fox, P. T., Miller, K. L., Glahn, D. C., Fox, P. M., Mackay, C. E., Filippini, N., Watkins, K. E., Toro, R., Laird, A. R., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0905267106 · Cited by 5,150 · see citing works
<i>Conn</i> : A Functional Connectivity Toolbox for Correlated and Anticorrelated Brain Networks
Whitfield-Gabrieli, S., & Nieto-Castanon, A. (2012) · Brain Connectivity · doi:10.1089/brain.2012.0073 · Cited by 4,885 · see citing works
A component based noise correction method (CompCor) for BOLD and perfusion based fMRI
Behzadi, Y., Restom, K., Liau, J., & Liu, T. T. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.04.042 · Cited by 4,502 · see citing works
Methods to detect, characterize, and remove motion artifact in resting state fMRI
Power, J. D., Mitra, A., Laumann, T. O., Snyder, A. Z., Schlaggar, B. L., & Petersen, S. E. (2014) · NeuroImage · doi:10.1016/j.neuroimage.2013.08.048 · Cited by 3,748 · see citing works
Functional and Effective Connectivity: A Review
Friston, K. J. (2011) · Brain Connectivity · doi:10.1089/brain.2011.0008 · Cited by 3,415 · see citing works
Rich-club organization of the human connectome
van den Heuvel, M. P., & Sporns, O. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.3539-11.2011 · Cited by 2,354 · see citing works
Functional anatomy of the basal ganglia. I. The cortico-basal ganglia-thalamo-cortical loop
Parent, A., & Hazrati, L.-N. (1995) · Brain Research Reviews · doi:10.1016/0165-0173(94)00007-c · Cited by 2,161 · see citing works
Network hubs in the human brain
van den Heuvel, M. P., & Sporns, O. (2013) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2013.09.012 · Cited by 2,123 · cited 2× · see citing works
“Hubs are thought to be of importance for overall brain functioning by serving integration and large-scale interaction (van den Heuvel and Sporns, 2013; Bell and Shine, 2016).”
BackgroundNichols, D. E. (2016) · Pharmacological Reviews · doi:10.1124/pr.115.011478 · Cited by 1,762 · see citing works
The hubs of the human connectome are generally implicated in the anatomy of brain disorders
Crossley, N. A., Mechelli, A., Scott, J., Carletti, F., Fox, P. T., McGuire, P., & Bullmore, E. T. (2014) · Brain · doi:10.1093/brain/awu132 · Cited by 1,166 · see citing works
Psilocybin induces schizophrenia-like psychosis in humans via a serotonin-2 agonist action
Vollenweider, F. X., Vollenweider-Scherpenhuyzen, M. F. I., Bäbler, A., Vogel, H., & Hell, D. (1998) · NeuroReport · doi:10.1097/00001756-199812010-00024 · Cited by 1,018 · see citing works
Neural correlates of the LSD experience revealed by multimodal neuroimaging
Carhart-Harris, R. L., Muthukumaraswamy, S., Roseman, L., Kaelen, M., Droog, W., Murphy, K., Tagliazucchi, E., Schenberg, E. E., Nest, T., Orban, C., et al. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1518377113 · Cited by 859 · see citing works
The organization of the human striatum estimated by intrinsic functional connectivity
Choi, E. Y., Yeo, B. T. T., & Buckner, R. L. (2012) · Journal of Neurophysiology · doi:10.1152/jn.00270.2012 · Cited by 746 · see citing works
Group comparison of resting-state FMRI data using multi-subject ICA and dual regression
Beckmann, C. F., Mackay, C., Filippini, N., & Smith, S. R. (2009) · NeuroImage · doi:10.1016/s1053-8119(09)71511-3 · Cited by 729 · see citing works
Psychometric evaluation of the altered states of consciousness rating scale (OAV)
Studerus, E., Gamma, A., & Vollenweider, F. X. (2010) · PLoS ONE · doi:10.1371/journal.pone.0012412 · Cited by 683 · see citing works
A Unitary Model of Schizophrenia
Andreasen, N. C. (1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.9.781 · Cited by 609 · see citing works
The Standardized Psychometric Assessment of Altered States of Consciousness (ASCs) in Humans
Dittrich, A. (1998) · Pharmacopsychiatry · doi:10.1055/s-2007-979351 · Cited by 577 · see citing works
Increased global functional connectivity correlates with LSD-induced ego dissolution
Tagliazucchi, E., Roseman, L., Kaelen, M., Orban, C., Muthukumaraswamy, S. D., Murphy, K., Laufs, H., Leech, R., McGonigle, J., Crossley, N., et al. (2016) · Current Biology · doi:10.1016/j.cub.2016.02.010 · Cited by 503 · see citing works
Palhano-Fontes, F., Andrade, K. C., Tofoli, L. F., Santos, A. C., Crippa, J. A. S., Hallak, J. E. C., Ribeiro, S., & de Araujo, D. B. (2015) · PLOS ONE · doi:10.1371/journal.pone.0118143 · Cited by 454 · see citing works
Intrinsic functional relations between human cerebral cortex and thalamus
Zhang, D., Snyder, A. Z., Fox, M. D., Sansbury, M. W., Shimony, J. S., & Raichle, M. E. (2008) · Journal of Neurophysiology · doi:10.1152/jn.90463.2008 · Cited by 437 · see citing works
Serotonin research: contributions to understanding psychoses
GEYER, M., & VOLLENWEIDER, F. (2008) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2008.06.006 · Cited by 427 · see citing works
Acute Effects of Lysergic Acid Diethylamide in Healthy Subjects
Schmid, Y., Enzler, F., Gasser, P., Grouzmann, E., Preller, K. H., Vollenweider, F. X., Brenneisen, R., Müller, F., Borgwardt, S., & Liechti, M. E. (2014) · Biological Psychiatry · doi:10.1016/j.biopsych.2014.11.015 · Cited by 409 · see citing works
Self-citationPreller, K. H., Herdener, M., Pokorny, T., Planzer, A., Kraehenmann, R., Stämpfli, P., Liechti, M. E., Seifritz, E., & Vollenweider, F. X. (2017) · Current Biology · doi:10.1016/j.cub.2016.12.030 · Cited by 402 · see citing works
Self-citationAnticevic, A., Haut, K. M., Murray, J. D., Repovš, G., Yang, G., Diehl, C., McEwen, S. C., Bearden, C. E., Addington, J., Goodyear, B. G., et al. (2015) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2015.0566 · Cited by 381 · see citing works
Receptor interaction profiles of novel psychoactive tryptamines compared with classic hallucinogens
Rickli, A., Moning, O. D., Hoener, M. C., & Liechti, M. E. (2016) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2016.05.001 · Cited by 379 · see citing works
Self-citationPsychedelics as Medicines: An Emerging New Paradigm
Nichols, D. E., Johnson, M., & Nichols, C. (2016) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt.557 · Cited by 373 · see citing works
Prediction of Psilocybin Response in Healthy Volunteers
Studerus, E., Gamma, A., Kometer, M., & Vollenweider, F. X. (2012) · PLoS ONE · doi:10.1371/journal.pone.0030800 · Cited by 369 · see citing works
Kelly, R. E., Alexopoulos, G. S., Wang, Z., Gunning, F. M., Murphy, C. F., Morimoto, S. S., Kanellopoulos, D., Jia, Z., Lim, K. O., & Hoptman, M. J. (2010) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2010.03.028 · Cited by 345 · see citing works
Noninvasive Functional and Structural Connectivity Mapping of the Human Thalamocortical System
Zhang, D., Snyder, A. Z., Shimony, J. S., Fox, M., & Raichle, M. E. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhp182 · Cited by 344 · see citing works
The paradoxical psychological effects of lysergic acid diethylamide LSD
Carhart-Harris, R. L., Kaelen, M., Bolstridge, M., Williams, T. M., Williams, L. T., Underwood, R., Feilding, A., & Nutt, D. J. (2016) · Psychological Medicine · doi:10.1017/s0033291715002901 · Cited by 293 · see citing works
Roseman, L., Leech, R., Feilding, A., Nutt, D., & Carhart-Harris, R. L. (2014) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2014.00204 · Cited by 274 · see citing works
Psychedelics not linked to mental health problems or suicidal behavior: A population study
Johansen, P.-Ø., & Krebs, T. (2015) · Journal of Psychopharmacology · doi:10.1177/0269881114568039 · Cited by 268 · see citing works
Functional Connectivity Measures After Psilocybin Inform a Novel Hypothesis of Early Psychosis
Carhart-Harris, R. L., Leech, R., Erritzoe, D., Williams, T. M., Stone, J. M., Evans, J., Sharp, D. J., Feilding, A., Wise, R. G., & Nutt, D. J. (2013) · Schizophrenia Bulletin · doi:10.1093/schbul/sbs117 · Cited by 256 · see citing works
The Thalamic Reticular Nucleus and Schizophrenia
Ferrarelli, F., & Tononi, G. (2010) · Schizophrenia Bulletin · doi:10.1093/schbul/sbq142 · Cited by 244 · see citing works
Modern clinical research on LSD
Liechti, M. E. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2017.86 · Cited by 236 · see citing works
Review of thalamocortical resting-state fMRI studies in schizophrenia
Giraldo‐Chica, M., & Woodward, N. D. (2016) · Schizophrenia Research · doi:10.1016/j.schres.2016.08.005 · Cited by 224 · see citing works
ICA model order selection of task co-activation networks
Ray, K. L., McKay, D., Fox, P. M., Riedel, M. C., Uecker, A. M., Beckmann, C. F., Smith, S. M., Fox, P. T., & Laird, A. R. (2013) · Frontiers in Neuroscience · doi:10.3389/fnins.2013.00237 · Cited by 203 · see citing works
Alterations of consciousness and mystical-type experiences after acute LSD in humans
Liechti, M. E., Dolder, P. C., & Schmid, Y. (2017) · Psychopharmacology · doi:10.1007/s00213-016-4453-0 · Cited by 198 · see citing works
Self-citationSubcortical contributions to large-scale network communication
Bell, P. T., & Shine, J. M. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.08.036 · Cited by 163 · see citing works
Cheng, W., Palaniyappan, L. K., Li, M., Kendrick, K. M., Zhang, J., Luo, Q., Liu, Z., Yu, R., Deng, W., Wang, Q., et al. (2015) · Schizophrenia · doi:10.1038/npjschz.2015.16 · Cited by 161 · see citing works
LSD Psychosis or LSD-Induced Schizophrenia?
Vardy, M. M. (1983) · Archives of General Psychiatry · doi:10.1001/archpsyc.1983.01790070067008 · Cited by 144 · see citing works
Increased thalamic resting‐state connectivity as a core driver of LSD‐induced hallucinations
Müller, F., Lenz, C., Dolder, P. C., Lang, U. E., Schmidt, A., Liechti, M. E., & Borgwardt, S. (2017) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.12818 · Cited by 137 · see citing works
Self-citationPharmacokinetics and Pharmacodynamics of Lysergic Acid Diethylamide in Healthy Subjects
Dolder, P. C., Schmid, Y., Steuer, A. E., Kraemer, T., Rentsch, K. M., Hammann, F., & Liechti, M. E. (2017) · Clinical Pharmacokinetics · doi:10.1007/s40262-017-0513-9 · Cited by 133 · see citing works
Self-citationNeurovascular factors in resting-state functional MRI
Liu, T. T. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2013.04.071 · Cited by 125 · see citing works
d-Lysergic Acid Diethylamide (LSD) as a Model of Psychosis: Mechanism of Action and Pharmacology
Gregorio, D. D., Comai, S., Posa, L., & Gobbi, G. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17111953 · Cited by 124 · see citing works
Functional topography of the thalamocortical system in human
Yuan, R., Di, X., Taylor, P. A., Gohel, S., Tsai, Y., & Biswal, B. B. (2015) · Brain Structure and Function · doi:10.1007/s00429-015-1018-7 · Cited by 123 · see citing works
Lisman, J. E., Pi, H. J., Zhang, Y., & Otmakhova, N. A. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.04.007 · Cited by 115 · see citing works
Dysfunctional Thalamus-Related Networks in Schizophrenia
Pinault, D. (2011) · Schizophrenia Bulletin · doi:10.1093/schbul/sbq165 · Cited by 105 · see citing works
Single-dose serotonergic stimulation shows widespread effects on functional brain connectivity
Klaassens, B. L., van Gorsel, H. C., Khalili-Mahani, N., van der Grond, J., Wyman, B. T., Whitcher, B., Rombouts, S. A. R. B., & van Gerven, J. M. A. (2015) · NeuroImage · doi:10.1016/j.neuroimage.2015.08.012 · Cited by 76 · see citing works
Hollister, L. E., & Hartman, A. M. (1962) · Comprehensive Psychiatry · doi:10.1016/s0010-440x(62)80024-8 · Cited by 73 · see citing works
Khalili‐Mahani, N., Chang, C. E., van Osch, M. J. P., Veer, I. M., van Buchem, M. A., Dahan, A., Beckmann, C. F., van Gerven, J., & Rombouts, S. A. R. B. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.09.044 · Cited by 65 · see citing works
Gouzoulis‐Mayfrank, E., Habermeyer, E., Hermle, L., Steinmeyer, A., Kunert, H. J., & Sass, H. (1998) · European Psychiatry · doi:10.1016/s0924-9338(99)80686-5 · Cited by 61 · see citing works
Structural Network Disorganization in Subjects at Clinical High Risk for Psychosis
Schmidt, A., Crossley, N. A., Harrisberger, F., Smieskova, R., Lenz, C., Riecher‐Rössler, A., Lang, U. E., McGuire, P. K., Fusar‐Poli, P., & Borgwardt, S. (2016) · Schizophrenia Bulletin · doi:10.1093/schbul/sbw110 · Cited by 55 · see citing works
Self-citationComparison of functional thalamic segmentation from seed-based analysis and ICA
Hale, J. R., Mayhew, S. D., Mullinger, K. J., Wilson, R. S., Arvanitis, T. N., Francis, S., & Bagshaw, A. P. (2015) · NeuroImage · doi:10.1016/j.neuroimage.2015.04.027 · Cited by 43 · see citing works
Spain, A., Howarth, C., Khrapitchev, A. A., Sharp, T., Sibson, N. R., & Martin, C. J. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2015.07.018 · Cited by 37 · see citing works
Hollister, L. E., & Sjoberg, B. M. (1964) · Comprehensive Psychiatry · doi:10.1016/s0010-440x(64)80030-4 · Cited by 36 · see citing works
Dolder, P. C., Liechti, M. E., & Rentsch, K. (2017) · Journal of Clinical Laboratory Analysis · doi:10.1002/jcla.22265 · Cited by 31 · see citing works
Self-citation
Flagged first, then by citations
Research works printed but not linked: 1
- Jones E. The Thalamus 2007 Cambridge University Press New York
Cited by
Sorted by citations
Psychedelic drugs: neurobiology and potential for treatment of psychiatric disorders
Vollenweider, F. X., & Preller, K. H. (2020) · Nature Reviews Neuroscience · doi:10.1038/s41583-020-0367-2 · Cited by 570 · see citing works
Doss, M. K., Považan, M., Rosenberg, M. D., Sepeda, N. D., Davis, A. K., Finan, P. H., Smith, G. S., Pekar, J. J., Barker, P. B., Griffiths, R. R., et al. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01706-y · Cited by 356 · see citing works
The neural basis of psychedelic action
Kwan, A. C., Olson, D. E., Preller, K. H., & Roth, B. L. (2022) · Nature Neuroscience · doi:10.1038/s41593-022-01177-4 · Cited by 312 · see citing works
Mason, N. L., Kuypers, K. P. C., Müller, F., Reckweg, J., Tse, D. H. Y., Toennes, S. W., Hutten, N. R. P. W., Jansen, J. F. A., Stiers, P., Feilding, A., et al. (2020) · Neuropsychopharmacology · doi:10.1038/s41386-020-0718-8 · Cited by 258 · see citing works
Self-citationGregorio, D. D., Aguilar‐Valles, A., Preller, K. H., Heifets, B. D., Hibicke, M., Mitchell, J., & Gobbi, G. (2020) · Journal of Neuroscience · doi:10.1523/jneurosci.1659-20.2020 · Cited by 261 · see citing works
Default Mode Network Modulation by Psychedelics: A Systematic Review
Gattuso, J. J., Perkins, D., Ruffell, S., Lawrence, A. J., Hoyer, D., Jacobson, L. H., Timmermann, C., Castle, D., Rossell, S. L., Downey, L. A., et al. (2023) · International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyac074 · Cited by 256 · see citing works
Psychedelics in Psychiatry: Neuroplastic, Immunomodulatory, and Neurotransmitter Mechanisms
Inserra, A., De Gregorio, D., & Gobbi, G. (2021) · Pharmacological Reviews · doi:10.1124/pharmrev.120.000056 · Cited by 232 · see citing works
SANTOS, R. G. D., Bouso, J. C., Alcázar‐Córcoles, M. Á., & Hallak, J. E. C. (2018) · Expert Review of Clinical Pharmacology · doi:10.1080/17512433.2018.1511424 · Cited by 228 · see citing works
Models of psychedelic drug action: modulation of cortical-subcortical circuits
Doss, M. K., Madden, M. B., Gaddis, A., Nebel, M. B., Griffiths, R. R., Mathur, B. N., & Barrett, F. S. (2021) · Brain · doi:10.1093/brain/awab406 · Cited by 198 · see citing works
Bershad, A. K., Schepers, S. T., Bremmer, M. P., Lee, R., & de Wit, H. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2019.05.019 · Cited by 175 · see citing works
LSD alters dynamic integration and segregation in the human brain
Luppi, A. I., Carhart-Harris, R. L., Roseman, L., Pappas, I., Menon, D. K., & Stamatakis, E. A. (2020) · NeuroImage · doi:10.1016/j.neuroimage.2020.117653 · Cited by 159 · see citing works
Madsen, M. K., Stenbæk, D. S., Arvidsson, A., Armand, S., Marstrand-Joergensen, M. R., Johansen, S. S., Línnet, K., Ozenne, B., Knudsen, G. M., & Fisher, P. M. (2021) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2021.06.001 · Cited by 145 · see citing works
Carhart-Harris, R. L. (2018) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000000467 · Cited by 133 · see citing works
Spontaneous and deliberate creative cognition during and after psilocybin exposure
Mason, N. L., Kuypers, K. P. C., Reckweg, J. T., Müller, F., Tse, D. H. Y., Rios, B. D., Toennes, S. W., Stiers, P. L. J., Feilding, A., & Ramaekers, J. G. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01335-5 · Cited by 129 · see citing works
Self-citationGirn, M., Roseman, L., Bernhardt, B. C., Smallwood, J., Carhart-Harris, R. L., & Spreng, R. N. (2022) · NeuroImage · doi:10.1016/j.neuroimage.2022.119220 · Cited by 115 · see citing works
Chronic pain and psychedelics: a review and proposed mechanism of action
Castellanos, J. P., Woolley, C., Bruno, K. A., Zeidan, F. Z., Halberstadt, A. L., & Furnish, T. J. (2020) · Regional Anesthesia & Pain Medicine · doi:10.1136/rapm-2020-101273 · Cited by 119 · see citing works
dos Santos, R. G., & Hallak, J. E. C. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.12.001 · Cited by 111 · see citing works
Reckweg, J. T., Uthaug, M. V., Szabó, A., Davis, A. K., Lancelotta, R., Mason, N. L., & Ramaekers, J. G. (2022) · Journal of Neurochemistry · doi:10.1111/jnc.15587 · Cited by 111 · see citing works
Classic Psychedelic Drugs: Update on Biological Mechanisms
Vollenweider, F. X., & Smallridge, J. W. (2022) · Pharmacopsychiatry · doi:10.1055/a-1721-2914 · Cited by 112 · see citing works
McCulloch, D. E.-W., Knudsen, G. M., Barrett, F. S., Doss, M. K., Carhart-Harris, R. L., Rosas, F. E., Deco, G., Kringelbach, M. L., Preller, K. H., Ramaekers, J. G., et al. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104689 · Cited by 108 · see citing works
Self-citationThe acute effects of classic psychedelics on memory in humans
Healy, C. J. (2021) · Psychopharmacology · doi:10.1007/s00213-020-05756-w · Cited by 95 · see citing works
Greenway, K. T., Garel, N., Jerome, L., & Feduccia, A. A. (2020) · Expert Review of Clinical Pharmacology · doi:10.1080/17512433.2020.1772054 · Cited by 94 · see citing works
Neural Mechanisms and Psychology of Psychedelic Ego Dissolution
Stoliker, D., Egan, G. F., Friston, K. J., & Razi, A. (2022) · Pharmacological Reviews · doi:10.1124/pharmrev.121.000508 · Cited by 89 · see citing works
Decreased directed functional connectivity in the psychedelic state
Barnett, L., Muthukumaraswamy, S. D., Carhart-Harris, R. L., & Seth, A. K. (2019) · NeuroImage · doi:10.1016/j.neuroimage.2019.116462 · Cited by 79 · see citing works
A complex systems perspective on psychedelic brain action
Girn, M., Rosas, F. E., Daws, R. E., Gallen, C. L., Gazzaley, A. H., & Carhart-Harris, R. L. (2023) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2023.01.003 · Cited by 72 · see citing works
Neural and subjective effects of inhaled N,N-dimethyltryptamine in natural settings
Pallavicini, C., Cavanna, F., Zamberlán, F., de la Fuente, L. A., Ilksoy, Y. A., Perl, Y. S., Arias, M., Romero, C., Carhart-Harris, R. L., Timmermann, C., et al. (2021) · Journal of Psychopharmacology · doi:10.1177/0269881120981384 · Cited by 83 · see citing works
Pharmacokinetics and subjective effects of a novel oral LSD formulation in healthy subjects
Holze, F., Duthaler, U., Vizeli, P., Müller, F., Borgwardt, S., & Liechti, M. E. (2019) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.13918 · Cited by 73 · see citing works
Self-citationRole of the 5-HT2A Receptor in Acute Effects of LSD on Empathy and Circulating Oxytocin
Holze, F., Avedisian, I., Varghese, N., Eckert, A., & Liechti, M. E. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.711255 · Cited by 67 · see citing works
Self-citationMertens, L. J., & Preller, K. H. (2021) · Pharmacopsychiatry · doi:10.1055/a-1341-1907 · Cited by 65 · see citing works
van Mulukom, V., Patterson, R. E., & van Elk, M. (2020) · Psychopharmacology · doi:10.1007/s00213-020-05568-y · Cited by 62 · see citing works
How everyday sounds can trigger strong emotions: ASMR, misophonia and the feeling of wellbeing
McGeoch, P. D., & Rouw, R. (2020) · BioEssays · doi:10.1002/bies.202000099 · Cited by 62 · see citing works
Kucyi, A., Kam, J. W. Y., Andrews‐Hanna, J. R., Kalina Christoff, A., & Whitfield, S. (2023) · Nature Mental Health · doi:10.1038/s44220-023-00133-w · Cited by 62 · see citing works
Low doses of lysergic acid diethylamide (LSD) increase reward-related brain activity
Glazer, J. E., Murray, C. H., Nusslock, R., Lee, R., & de Wit, H. (2022) · Neuropsychopharmacology · doi:10.1038/s41386-022-01479-y · Cited by 56 · see citing works
Aqil, M., & Roseman, L. (2022) · Neuropharmacology · doi:10.1016/j.neuropharm.2022.109300 · Cited by 58 · see citing works
A whole-brain model of the neural entropy increase elicited by psychedelic drugs
Herzog, R. A., Mediano, P. A. M., Rosas, F. E., Lodder, P., Carhart-Harris, R. L., Perl, Y. S., Tagliazucchi, E., & Cofré, R. (2023) · Scientific Reports · doi:10.1038/s41598-023-32649-7 · Cited by 55 · see citing works
Holze, F., Singh, N., Liechti, M., & D'Souza, D. (2024) · Biological Psychiatry: Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2024.01.007 · Cited by 44 · see citing works
Self-citationEffective Connectivity of Functionally Anticorrelated Networks Under Lysergic Acid Diethylamide
Stoliker, D., Novelli, L., Vollenweider, F. X., Egan, G. F., Preller, K. H., & Razi, A. (2022) · Biological Psychiatry · doi:10.1016/j.biopsych.2022.07.013 · Cited by 54 · see citing works
Husain, M. I., Ledwos, N., Fellows, E., Baer, J., Rosenblat, J. D., Blumberger, D. M., Mulsant, B. H., & Castle, D. J. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.1076459 · Cited by 50 · see citing works
Doss, M. K., May, D. G., Johnson, M. W., Clifton, J. M., Hedrick, S. L., Prisinzano, T. E., Griffiths, R. R., & Barrett, F. S. (2020) · Scientific Reports · doi:10.1038/s41598-020-73216-8 · Cited by 52 · see citing works
RETRACTED ARTICLE: A mechanistic model of the neural entropy increase elicited by psychedelic drugs
Herzog, R. A., Mediano, P. A. M., Rosas, F. E., Carhart-Harris, R. L., Perl, Y. S., Tagliazucchi, E., & Cofré, R. (2020) · Scientific Reports · doi:10.1038/s41598-020-74060-6 · Cited by 48 · see citing works
RetractedAyahuasca: A review of historical, pharmacological, and therapeutic aspects
Ruffell, S., Crosland‐Wood, M., Palmer, R., Netzband, N., Tsang, W., Weiss, B., Gandy, S., Cowley‐Court, T., Halman, A., McHerron, D., et al. (2023) · Psychiatry and Clinical Neurosciences Reports · doi:10.1002/pcn5.146 · Cited by 54 · see citing works
Stoliker, D., Novelli, L., Vollenweider, F. X., Egan, G. F., Preller, K. H., & Razi, A. (2024) · Biological Psychiatry · doi:10.1016/j.biopsych.2024.01.002 · Cited by 44 · see citing works
Mindfulness meditation and psychedelics: potential synergies and commonalities
Holas, P., & Kamińska, J. (2023) · Pharmacological Reports · doi:10.1007/s43440-023-00551-8 · Cited by 43 · see citing works
“…with functional magnetic resonance imaging (fMRI) that during psychedelic experience, the DMN is modulated, which sharply reduces blood flow and connection within its nodes [46], leading to decreased functional connectivity within the DMN and increased between-network connectivity [47, 48].”
BackgroundYu, Z., Burback, L., Winkler, O., Xu, L., Dennett, L., Vermetten, E. H. G. J. M., Greenshaw, A. J., Li, X., Milne, M., Wang, F., et al. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1386321 · Cited by 42 · see citing works
Avram, M., Müller, F., Rogg, H. V., Korda, A. I., Andreou, C., Holze, F., Vizeli, P., Ley, L., Liechti, M. E., & Borgwardt, S. (2022) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2022.04.003 · Cited by 41 · see citing works
Self-citationThe effect of lysergic acid diethylamide (LSD) on whole-brain functional and effective connectivity
Bedford, P., Hauke, D. J., Wang, Z., Röth, V., Nagy-Huber, M., Holze, F., Ley, L., Vizeli, P., Liechti, M. E., Borgwardt, S., et al. (2023) · Neuropsychopharmacology · doi:10.1038/s41386-023-01574-8 · Cited by 40 · see citing works
Self-citationMüller, F., Holze, F., Dolder, P. C., Ley, L., Vizeli, P., Soltermann, A., Liechti, M. E., & Borgwardt, S. (2020) · Neuropsychopharmacology · doi:10.1038/s41386-020-00906-2 · Cited by 37 · see citing works
Self-citationZoubi, O. A., Misaki, M., Bodurka, J., Kuplicki, R., Wohlrab, C., Schoenhals, W. A., Refai, H. H., Khalsa, S. S., Stein, M. B., Paulus, M. P., et al. (2021) · Human Brain Mapping · doi:10.1002/hbm.25429 · Cited by 37 · see citing works
Psychedelics for acquired brain injury: a review of molecular mechanisms and therapeutic potential
Allen, J., Dames, S., Foldi, C. J., & Shultz, S. R. (2024) · Molecular Psychiatry · doi:10.1038/s41380-023-02360-0 · Cited by 38 · see citing works
Gaddis, A., Lidstone, D. E., Nebel, M. B., Griffiths, R. R., Mostofsky, S. H., Mejia, A. F., & Barrett, F. S. (2022) · NeuroImage · doi:10.1016/j.neuroimage.2022.119434 · Cited by 37 · see citing works
A Systematic Review of Study Design and Placebo Controls in Psychedelic Research
Wen, A. Q., Singhal, N., Jones, B. D. M., Zeifman, R. J., Mehta, S. H., Shenasa, M. A., Blumberger, D. M., Daskalakis, Z. J., & Weissman, C. R. (2023) · Psychedelic Medicine · doi:10.1089/psymed.2023.0028 · Cited by 36 · see citing works
Increased sensitivity to strong perturbations in a whole-brain model of LSD
Jobst, B., Atasoy, S., Ponce‐Alvarez, A., Sanjuán, A., Roseman, L., Kaelen, M., Carhart-Harris, R. L., Kringelbach, M. L., & Deco, G. (2021) · NeuroImage · doi:10.1016/j.neuroimage.2021.117809 · Cited by 34 · see citing works
Dourron, H. M., Strauss, C. K., & Hendricks, P. S. (2022) · Pharmacological Reviews · doi:10.1124/pharmrev.121.000514 · Cited by 31 · see citing works
Psilocybin and Other Classic Psychedelics in Depression
Nutt, D., Peill, J. M., Weiss, B., Godfrey, K., Carhart-Harris, R. L., & Erritzøe, D. (2023) · Current topics in behavioral neurosciences · doi:10.1007/7854_2023_451 · Cited by 37 · see citing works
Psychedelics in the treatment of unipolar and bipolar depression
Bosch, O. G., Halm, S., & Seifritz, E. (2022) · International Journal of Bipolar Disorders · doi:10.1186/s40345-022-00265-5 · Cited by 38 · see citing works
Müller, F., Liechti, M. E., Lang, U. E., & Borgwardt, S. (2018) · Progress in Brain Research · doi:10.1016/bs.pbr.2018.08.004 · Cited by 31 · see citing works
Self-citationHow do serotonergic psychedelics treat depression: The potential role of neuroplasticity
Artin, H., Zisook, S., & Ramanathan, D. (2021) · World Journal of Psychiatry · doi:10.5498/wjp.v11.i6.201 · Cited by 33 · see citing works
Exploring mechanisms of psychedelic action using neuroimaging
Erritzøe, D., Timmermann, C., Godfrey, K. E. M., Castro-Rodrigues, P., Peill, J. M., Carhart-Harris, R. L., Nutt, D., & Wall, M. B. (2024) · Nature Mental Health · doi:10.1038/s44220-023-00172-3 · Cited by 33 · see citing works
Are Psychedelic Medicines the Reset for Chronic Pain? Preliminary Findings and Research Needs
Zia, F., Baumann, M., Belouin, S., Dworkin, R., Ghauri, M. H., Hendricks, P. S., Henningfield, J., Lanier, R., Ross, S., & Berger, A. (2023) · Neuropharmacology · doi:10.1016/j.neuropharm.2023.109528 · Cited by 26 · see citing works
Avram, M., Fortea, L., Wollner, L., Coenen, R., Korda, A. I., Rogg, H. V., Holze, F., Vizeli, P., Ley, L., Raduà, J., et al. (2024) · Molecular Psychiatry · doi:10.1038/s41380-024-02734-y · Cited by 29 · see citing works
Self-citationA role for the serotonin 2A receptor in the expansion and functioning of human transmodal cortex
Luppi, A. I., Girn, M., Rosas, F. E., Timmermann, C., Roseman, L., Erritzøe, D., Nutt, D., Stamatakis, E. A., Spreng, R. N., Xing, L., et al. (2023) · Brain · doi:10.1093/brain/awad311 · Cited by 30 · see citing works
Sapienza, J., Bosia, M., Spangaro, M., Martini, F., Agostoni, G., Cuoco, F., Cocchi, F., & Cavallaro, R. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01721-5 · Cited by 28 · see citing works
Psychedelics as potential catalysts of scientific creativity and insight
Gandy, S., Bonnelle, V., Jacobs, E., & Luke, D. P. (2022) · Drug Science Policy and Law · doi:10.1177/20503245221097649 · Cited by 26 · see citing works
The mechanistic divide in psychedelic neuroscience: An unbridgeable gap?
Barksdale, B. R., Doss, M. K., Fonzo, G. A., & Nemeroff, C. B. (2024) · Neurotherapeutics · doi:10.1016/j.neurot.2024.e00322 · Cited by 26 · see citing works
Psilocybin-induced default mode network hypoconnectivity is blunted in alcohol-dependent rats
Reinwald, J., Schmitz, C. N., Skorodumov, I., Kuchař, M., Weber‐Fahr, W., Spanagel, R., & Meinhardt, M. W. (2023) · Translational Psychiatry · doi:10.1038/s41398-023-02690-1 · Cited by 25 · see citing works
Padawer-Curry, J. A., Krentzman, O. J., Kuo, C., Wang, X., Bice, A. R., Nicol, G. E., Snyder, A. Z., Siegel, J. S., McCall, J. G., & Bauer, A. Q. (2025) · Nature Neuroscience · doi:10.1038/s41593-025-02069-z · Cited by 28 · see citing works
Felsch, C. L., & Kuypers, K. P. C. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104724 · Cited by 25 · see citing works
Large-scale brain networks and Freudian ego
Dimkov, P. R. (2019) · Psychological Thought · doi:10.5964/psyct.v12i2.328 · Cited by 23 · see citing works
Tolle, H. M., Farah, J. C., Mallaroni, P., Mason, N. L., Ramaekers, J. G., & Amico, E. (2023) · Network Neuroscience · doi:10.1162/netn_a_00349 · Cited by 22 · see citing works
Shinozuka, K., Jerotic, K., Mediano, P. A. M., Zhao, A. T., Preller, K. H., Carhart-Harris, R. L., & Kringelbach, M. L. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-03187-1 · Cited by 22 · see citing works
An international mega-analysis of psychedelic drug effects on brain circuit function
Girn, M., Doss, M. K., Roseman, L., Preller, K. H., Palhano-Fontes, F., Pasquini, L., Barrett, F. S., Mallaroni, P., Mason, N. L., Timmermann, C., et al. (2026) · Nature Medicine · doi:10.1038/s41591-026-04287-9 · Cited by 23 · see citing works
Self-citationRankaduwa, S., & Owen, A. M. (2023) · Neuroscience of Consciousness · doi:10.1093/nc/niad001 · Cited by 22 · see citing works
Bedside to bench: the outlook for psychedelic research
Acero, V. P., Cribas, E. S., Browne, K. D., Rivellini, O. M., Burrell, J. C., O’Donnell, J. C., Das, S., & Cullen, D. K. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1240295 · Cited by 22 · see citing works
Not in the drug, not in the brain: Causality in psychedelic experiences from an enactive perspective
Meling, D., & Scheidegger, M. (2023) · Frontiers in Psychology · doi:10.3389/fpsyg.2023.1100058 · Cited by 20 · see citing works
Contributions of Basal Ganglia Circuits to Perception, Attention, and Consciousness
Redinbaugh, M. J., & Saalmann, Y. B. (2024) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_02177 · Cited by 19 · see citing works
How Psychedelics Modulate Multiple Memory Mechanisms in Posttraumatic Stress Disorder
Doss, M. K., DeMarco, A., Dunsmoor, J. E., Cisler, J. M., Fonzo, G. A., & Nemeroff, C. B. (2024) · Drugs · doi:10.1007/s40265-024-02106-4 · Cited by 20 · see citing works
Oña, G., Sampedro, F., Romero, S., Valle, M., Camacho, V., Migliorelli, C., Mañanas, M. Á., Antonijoan, R. M., Puntes, M., Coimbra, J., et al. (2021) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyab063 · Cited by 18 · see citing works
Barrett, F. S., Zhou, Y., Carbonaro, T. M., Roberts, J., Smith, G. S., Griffiths, R. R., & Wong, D. F. (2022) · Frontiers in Neuroergonomics · doi:10.3389/fnrgo.2021.784576 · Cited by 18 · see citing works
Ruban, A., & Kołodziej, A. (2018) · Neuropsychiatria i Neuropsychologia · doi:10.5114/nan.2018.81249 · Cited by 18 · see citing works
fMRI Evidence for Default Mode Network Deactivation Associated with Rapid Eye Movements in Sleep
Hong, C. C.-H., Fallon, J., & Friston, K. J. (2021) · Brain Sciences · doi:10.3390/brainsci11111528 · Cited by 18 · see citing works
Inserra, A., Piot, A., Gregorio, D. D., & Gobbi, G. (2023) · CNS Drugs · doi:10.1007/s40263-023-01008-5 · Cited by 17 · see citing works
Linguiti, S., Vogel, J. W., Sydnor, V. J., Pines, A. R., Wellman, N., Basbaum, A. I., Eickhoff, C. R., Eickhoff, S. B., Edwards, R. R., Larsen, B., et al. (2023) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2023.105421 · Cited by 17 · see citing works
Neural and subjective effects of inhaled DMT in natural settingsPreprint
Pallavicini, C., Cavanna, F., Zamberlán, F., de la Fuente, L. A., Perl, Y. S., Arias, M., Romero, C., Carhart-Harris, R. L., Timmermann, C., & Tagliazucchi, E. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.08.19.258145 · Cited by 17 · see citing works
Acute psilocybin increased cortical activities in rats
Liu, J., Wang, Y., Xia, K., Wu, J., Zheng, D., Cai, A., Yan, H., & Su, R. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1168911 · Cited by 16 · see citing works
RetractedSynthetic surprise as the foundation of the psychedelic experience
Filippo, R. D., & Schmitz, D. (2024) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2024.105538 · Cited by 15 · see citing works
Domenico, C. M., Haggerty, D. C., Mou, X., & Ji, D. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109714 · Cited by 17 · see citing works
Lyon, A. (2023) · doi:10.1093/oso/9780198843757.001.0001 · Cited by 17 · see citing works
Berkovitch, L., Fauvel, B., Preller, K. H., & Gaillard, R. (2025) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2025.106239 · Cited by 14 · see citing works
Wong, S., Yu, A. Y., Fabiano, N., Finkelstein, O., Pasricha, A., Jones, B. D. M., Rosenblat, J. D., Blumberger, D. M., Mulsant, B. H., & Husain, M. I. (2023) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2023.2251133 · Cited by 14 · see citing works
Stewart, B., Dean, J. G., Koek, A. Y., Chua, J. P., Wabl, R., Martin, K., Davoodian, N., Becker, C. J., Himedan, M., Kim, A., et al. (2020) · Pharmacology Research & Perspectives · doi:10.1002/prp2.688 · Cited by 14 · see citing works
McCulloch, D. E.-W., Knudsen, G. M., Barrett, F. S., Doss, M. K., Deco, G., Carhart-Harris, R. L., Rosas, F. E., Preller, K. H., Ramaekers, J. G., Mason, N. L., et al. (2021) · doi:10.31234/osf.io/64kyg · Cited by 14 · see citing works
Self-citationGhaw, A., Chunduri, A., Chang, A., Ortiz, R. J., Kozlowska, M., Kulkarni, P. P., & Ferris, C. F. (2024) · Brain Communications · doi:10.1093/braincomms/fcae194 · Cited by 13 · see citing works
Pain and Perception: Exploring Psychedelics as Novel Therapeutic Agents in Chronic Pain Management
Strand, N. H., Whitney, M. A., Johnson, B. W., Dunn, T., Attanti, S., Maloney, J. A., Misra, L., Gomez, D., Viswanath, O., Emami, E., et al. (2025) · Current Pain and Headache Reports · doi:10.1007/s11916-024-01353-0 · Cited by 14 · see citing works
Silverstein, B. H., Kolbman, N., Nelson, A., Liu, T., Guzzo, P. R., Gilligan, J., Lee, U., Mashour, G. A., Vanini, G., & Pal, D. (2025) · Translational Psychiatry · doi:10.1038/s41398-025-03308-4 · Cited by 18 · see citing works
A potential role for psilocybin in the treatment of obsessive-compulsive disorder
Jacobs, E. (2020) · Journal of Psychedelic Studies · doi:10.1556/2054.2020.00128 · Cited by 16 · see citing works
Editorial: Psychedelic sociality: Pharmacological and extrapharmacological perspectives
Roseman, L., Preller, K. H., Fotiou, E., & Winkelman, M. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.979764 · Cited by 13 · see citing works
Schmid, Y., & Bershad, A. K. (2024) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2024.02.001 · Cited by 14 · see citing works
Weyrich, L., Arif, Y., Schantell, M. D., Johnson, H. J., Willett, M. P., Okelberry, H. J., & Wilson, T. W. (2023) · Psychopharmacology · doi:10.1007/s00213-023-06318-6 · Cited by 12 · see citing works
Buchborn, T., Lyons, T., Song, C., Feilding, A., & Knöpfel, T. (2020) · Journal of Psychopharmacology · doi:10.1177/0269881120903465 · Cited by 11 · see citing works
- Authors
- Müller, F., Dolder, P. C., Schmidt, A., Liechti, M. E., & Borgwardt, S.
- Affiliations
- University of Basel (CH)
- Corresponding author
- Borgwardt, Stefan
- Venue
- NeuroImage: Clinical
- Publisher
- Elsevier BV
- Published
- 2018
- Volume
- 18
- Pages
- 694-701
- ISSN
- 2213-1582 (ISSN-L)
- PMC
- PMC5857492
- OpenAlex
- W2792211781
- Cited by
- 174
- References
- 61
- Citations by year
- 2026: 15 · 2025: 21 · 2024: 23 · 2023: 45 · 2022: 22 · 2021: 19 · 2020: 19 · 2019: 6 · 2018: 4
- FWCI
- 14.10
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- NeuroImage Clinical (publishedVersion, cc-by-nc-nd)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- edoc (University of Basel) (acceptedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- edoc (University of Basel)
- Funders
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (320030_170249)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Psychedelics and Drug Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Hallucinations in medical conditions
- Keywords
- LSD, hallucinogens, resting-state functional connectivity, network hubs, default mode network, seed-to-voxel analysis, altered states of consciousness, psychosis, thalamus, striatum, precuneus, anterior cingulate cortex, visual network, sensorimotor network, auditory network
- MeSH terms
- Adult, Brain, Brain Mapping, Double-Blind Method, Female, Hallucinogens, Humans, Image Processing, Computer-Assisted, Lysergic Acid Diethylamide, Magnetic Resonance Imaging, Male, Middle Aged, Nerve Net, Cross-Over Studies
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