The Psychedelic State Induced by Ayahuasca Modulates the Activity and Connectivity of the Default Mode Network
Open accessAbstract
The experiences induced by psychedelics share a wide variety of subjective features, related to the complex changes in perception and cognition induced by this class of drugs. A remarkable increase in introspection is at the core of these altered states of consciousness. Self-oriented mental activity has been consistently linked to the Default Mode Network (DMN), a set of brain regions more active during rest than during the execution of a goal-directed task. Here we used fMRI technique to inspect the DMN during the psychedelic state induced by Ayahuasca in ten experienced subjects. Ayahuasca is a potion traditionally used by Amazonian Amerindians composed by a mixture of compounds that increase monoaminergic transmission. In particular, we examined whether Ayahuasca changes the activity and connectivity of the DMN and the connection between the DMN and the task-positive network (TPN). Ayahuasca caused a significant decrease in activity through most parts of the DMN, including its most consistent hubs: the Posterior Cingulate Cortex (PCC)/Precuneus and the medial Prefrontal Cortex (mPFC). Functional connectivity within the PCC/Precuneus decreased after Ayahuasca intake. No significant change was observed in the DMN-TPN orthogonality. Altogether, our results support the notion that the altered state of consciousness induced by Ayahuasca, like those induced by psilocybin (another serotonergic psychedelic), meditation and sleep, is linked to the modulation of the activity and the connectivity of the DMN.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Traditions of meditation and ritual use of medicinal plants, fungi, and animals with consciousness-altering capacities have similar abilities to induce trance states, although these are often used in more inward-focused settings to explore one's own body/mind and connection to the adjoining socio-ecological environment.
“Traditions of meditation and ritual use of medicinal plants, fungi, and animals with consciousness-altering capacities have similar abilities to induce trance states, although these are often used in more inward-focused settings to explore one's own body/mind and connection to the adjoining socio-ecological environment-even if practiced as a group (Millière et al. 2018; Palhano-Fontes et al. 2015;”
From Cultural Evolution of Religion, Spirituality and Ritual: Impacts On Human Cooperation (2024) · cites this paper as Palhano-Fontes et al. 2015
Split into 2 atoms — 0 confirmed, 2 partially supported, 0 disputed, 0 misattributed, 0 unverifiable. Expand the claim to see per-atom verdicts.
Experimental — accuracy not yet measuredDuring psychedelic experience, fMRI shows the default mode network is modulated, sharply reducing blood flow and connection within its nodes, leading to decreased functional connectivity within the DMN and increased between-network connectivity.
“It has been demonstrated with functional magnetic resonance imaging (fMRI) that during psychedelic experience, the DMN is modulated, which sharply reduces blood flow and connection within its nodes [46], leading to decreased functional connectivity within the DMN and increased between-network connectivity [47, 48].”
From Mindfulness meditation and psychedelics: potential synergies and commonalities (2023) · cites this paper as [47]
The Results report reduced DMN BOLD activity after ayahuasca and reduced functional connectivity within the PCC/precuneus. They do not establish a reduction in blood flow or connectivity across all DMN nodes; connectivity between the mPFC and PCC did not change significantly. The increased between-network connectivity clause is cited to [47, 48], not this source. (LLM, conf=0.88)
Experimental — accuracy not yet measuredAdministration of various psychedelic drugs has led to transient deactivation of certain DMN hubs, including the mPFC, PCC and anterior cingulate cortex (ACC).
“Similarly, the administration of various psychedelic drugs has led to transient deactivation of certain DMN hubs, including the mPFC, PCC and anterior cingulate cortex (ACC) (45, 114).”
From Examining the Potential Synergistic Effects Between Mindfulness Training and Psychedelic-Assisted Therapy (2021) · cites this paper as [114]
The Results report significantly reduced activity in the ACC, PCC and mPFC after ayahuasca intake; the Introduction also notes reduced DMN activity with psilocybin. The paper does not establish that deactivation in all three regions occurs with various psychedelic drugs, or demonstrate that the reductions are transient. (LLM, conf=0.84)
Experimental — accuracy not yet measuredPalhano-Fontes et al. (2015) reported decreased BOLD signal in DMN nodes including the MPFC and PCC during ayahuasca intoxication.
“Palhano-Fontes et al. (2015) reported decreased BOLD signal in DMN nodes including the MPFC and PCC during ayahuasca intoxication.”
From Self unbound: ego dissolution in psychedelic experience (2017) · cites this paper as Palhano-Fontes et al. 2015
Classic psychedelics acutely reduce activity and internal functional connectivity within the DMN.
“A number of studies have demonstrated that classic psychedelics acutely reduce activity and internal functional connectivity within the DMN [28, 29], potentially reducing abstracted (perceptually decoupled) and self-referential rumination, a hallmark of depressotypic thinking [30–32].”
From The psychological processes of classic psychedelics in the treatment of depression: a systematic review protocol (2022) · cites this paper as [28]
Ayahuasca decreases functional connectivity within the prefrontal cortex and in connections with other areas involved in a wide range of ordinary cognitive processes.
“Ayahuasca decreases the functional connectivity within the prefrontal cortex and in connections with other areas of the brain that are involved in a wide range of ordinary cognitive processes (Palhano-Fontes et al., 2015).”
From The therapeutic potentials of Ayahuasca: possible effects against various diseases of civilization (2016) · cites this paper as Palhano-Fontes et al., 2015
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
A default mode of brain function
Raichle, M. E., MacLeod, A. M., Snyder, A. Z., Powers, W. J., Gusnard, D. A., & Shulman, G. L. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.2.676 · Cited by 12,190 · see citing works
<i>The Brain's Default Network</i>: <i>Anatomy, Function, and Relevance to Disease</i>
Buckner, R. L., Andrews‐Hanna, J. R., & Schacter, D. L. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1440.011 · Cited by 9,761 · see citing works
A Rating Scale for Mania: Reliability, Validity and Sensitivity
Young, R. C., Biggs, J. T., Ziegler, V. E., & Meyer, D. A. (1978) · British Journal of Psychiatry · doi:10.1192/bjp.133.5.429 · Cited by 8,744 · see citing works
The human brain is intrinsically organized into dynamic, anticorrelated functional networks
Fox, M. D., Snyder, A. Z., Vincent, J. L., Corbetta, M., Van Essen, D. C., & Raichle, M. E. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504136102 · Cited by 8,553 · see citing works
The varieties of religious experience: A study in human nature.
James, W. (1902) · doi:10.1037/10004-000 · Cited by 5,204 · see citing works
Calamita, E., Schmid, M., Kunz, M., Ndebele-Murisa, M. R., Magadza, C. H. D., Nyambe, I., & Wehrli, B. (2019) · Figshare · doi:10.26181/6153922fe919c · Cited by 4,222 · see citing works
Greicius, M. D., Srivastava, G., Reiss, A. L., & Menon, V. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308627101 · Cited by 3,684 · see citing works
Self-referential processing in our brain—A meta-analysis of imaging studies on the self
Northoff, G., Heinzel, A., de Greck, M., Bermpohl, F., Dobrowolny, H., & Panksepp, J. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2005.12.002 · Cited by 2,792 · see citing works
Wandering minds: the default network and stimulus-independent thought
Mason, M. F., Norton, M. I., Van Horn, J. D., Wegner, D. M., Grafton, S. T., & Macrae, C. N. (2007) · Science · doi:10.1126/science.1131295 · Cited by 2,792 · see citing works
Circular analysis in systems neuroscience: the dangers of double dipping
Kriegeskorte, N., Simmons, W. K., Bellgowan, P. S. F., & Baker, C. I. (2009) · Nature Neuroscience · doi:10.1038/nn.2303 · Cited by 2,696 · see citing works
Buckner, R. L., & Carroll, D. C. (2007) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2006.11.004 · Cited by 2,691 · see citing works
Murphy, K., Birn, R. M., Handwerker, D. A., Jones, T. B., & Bandettini, P. A. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2008.09.036 · Cited by 2,387 · see citing works
Smallwood, J., & Schooler, J. W. (2006) · Psychological Bulletin · doi:10.1037/0033-2909.132.6.946 · Cited by 2,067 · see citing works
The global signal and observed anticorrelated resting state brain networks
Fox, M. D., Zhang, D., Snyder, A. Z., & Raichle, M. E. (2009) · Journal of Neurophysiology · doi:10.1152/jn.90777.2008 · Cited by 1,877 · see citing works
REST: A Toolkit for Resting-State Functional Magnetic Resonance Imaging Data Processing
Song, X., Dong, Z.-Y., Long, X., Li, S., Zuo, X., Zhu, C.-Z., Yong He, A., Yan, C., & Zang, Y. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025031 · Cited by 1,864 · see citing works
The default mode network and self-referential processes in depression
Sheline, Y. I., Barch, D. M., Price, J. L., Rundle, M. M., Vaishnavi, S. N., Snyder, A. Z., Mintun, M. A., Wang, S., Coalson, R. S., & Raichle, M. E. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0812686106 · Cited by 1,480 · see citing works
Brewer, J. A., Worhunsky, P. D., Gray, J. R., Tang, Y.-Y., Weber, J., & Kober, H. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1112029108 · Cited by 1,409 · see citing works
Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin
Carhart-Harris, R. L., Erritzoe, D., Williams, T., Stone, J. M., Reed, L. J., Colasanti, A., Tyacke, R. J., Leech, R., Malizia, A. L., Murphy, K., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1119598109 · Cited by 1,172 · see citing works
Uddin, L. Q., Clare Kelly, A. M., Biswal, B. B., Xavier Castellanos, F., & Milham, M. P. (2009) · Human Brain Mapping · doi:10.1002/hbm.20531 · Cited by 1,135 · see citing works
Aberrant “Default Mode” Functional Connectivity in Schizophrenia
Garrity, A. G., Pearlson, G. D., McKiernan, K., Lloyd, D., Kiehl, K. A., & Calhoun, V. D. (2007) · American Journal of Psychiatry · doi:10.1176/ajp.2007.164.3.450 · Cited by 1,114 · see citing works
Neural correlates of attentional expertise in long-term meditation practitioners
Brefczynski-Lewis, J. A., Lutz, A., Schaefer, H. S., Levinson, D. B., & Davidson, R. J. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0606552104 · Cited by 983 · see citing works
Weissenbacher, A., Kasess, C., Gerstl, F., Lanzenberger, R., Moser, E., & Windischberger, C. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.05.005 · Cited by 776 · see citing works
Decoupling of the brain's default mode network during deep sleep
Horovitz, S. G., Braun, A. R., Carr, W. S., Picchioni, D., Balkin, T. J., Fukunaga, M., & Duyn, J. H. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0901435106 · Cited by 685 · see citing works
Hasenkamp, W., Wilson-Mendenhall, C. D., Duncan, E., & Barsalou, L. W. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2011.07.008 · Cited by 643 · see citing works
Boveroux, P., Vanhaudenhuyse, A., Bruno, M.-A., Noirhomme, Q., Lauwick, S., Luxen, A., Degueldre, C., Plenevaux, A., Schnakers, C., Phillips, C., et al. (2010) · Anesthesiology · doi:10.1097/aln.0b013e3181f697f5 · Cited by 630 · see citing works
Laird, A. R., Eickhoff, S. B., Li, K., Robin, D. A., Glahn, D. C., & Fox, P. T. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.4004-09.2009 · Cited by 550 · see citing works
The Hallucinogen <i>N,N</i> -Dimethyltryptamine (DMT) Is an Endogenous Sigma-1 Receptor Regulator
Fontanilla, D., Johannessen, M., Hajipour, A. R., Cozzi, N. V., Jackson, M. B., & Ruoho, A. E. (2009) · Science · doi:10.1126/science.1166127 · Cited by 535 · see citing works
Persistent default‐mode network connectivity during light sedation
Greicius, M. D., Kiviniemi, V. J., Tervonen, O. A., Vainionpää, V., Alahuhta, S., Reiss, A. L., & Menon, V. (2008) · Human Brain Mapping · doi:10.1002/hbm.20537 · Cited by 514 · see citing works
Development of the Brain's Default Mode Network from Wakefulness to Slow Wave Sleep
Sämann, P. G., Wehrle, R., Hoehn, D., Spoormaker, V. I., Peters, H., Tully, C., Holsboer, F., & Czisch, M. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhq295 · Cited by 399 · see citing works
McKenna, D. J., Towers, G. H. N., & Abbott, F. (1984) · Journal of Ethnopharmacology · doi:10.1016/0378-8741(84)90003-5 · Cited by 398 · see citing works
Riba, J., Valle, M., Urbano, G., Yritia, M., Morte, A., & Barbanoj, M. J. (2003) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.103.049882 · Cited by 390 · see citing works
Effects of Meditation Experience on Functional Connectivity of Distributed Brain Networks
Hasenkamp, W., & Barsalou, L. W. (2012) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2012.00038 · Cited by 367 · see citing works
The future of fMRI connectivity
Smith, S. M. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.01.022 · Cited by 355 · see citing works
Pharmacokinetics of Hoasca alkaloids in healthy humans
Callaway, J. C., McKenna, D. J., Grob, C. S., Brito, G. S., Raymon, L. P., Poland, R. E., Andrade, E. O., Andrade, E. O., & Mash, D. C. (1999) · Journal of Ethnopharmacology · doi:10.1016/s0378-8741(98)00168-8 · Cited by 318 · see citing works
Riba, J., Rodríguez-Fornells, A., Urbano, G., Morte, A., Antonijoan, R., Montero, M., Callaway, J. C., & Barbanoj, M. J. (2001) · Psychopharmacology · doi:10.1007/s002130000606 · Cited by 303 · see citing works
Psychedelics and the Human Receptorome
Ray, T. S. (2010) · PLoS ONE · doi:10.1371/journal.pone.0009019 · Cited by 300 · see citing works
Dysfunction of the Default Mode Network in Parkinson Disease
van Eimeren, T., Monchi, O., Ballanger, B., & Strafella, A. P. (2009) · Archives of Neurology · doi:10.1001/archneurol.2009.97 · Cited by 262 · see citing works
Increased default mode network connectivity associated with meditation
Jang, J. H., Jung, W. H., Kang, D.-H., Byun, M. S., Kwon, S. J., Choi, C.-H., & Kwon, J. S. (2011) · Neuroscience Letters · doi:10.1016/j.neulet.2010.10.056 · Cited by 260 · cited 1× · see citing works
“In its turn, meditation has been consistently associated with stronger coupling between anterior and posterior nodes of the DMN [17,31,48].”
BackgroundFunctional Connectivity Measures After Psilocybin Inform a Novel Hypothesis of Early Psychosis
Carhart-Harris, R. L., Leech, R., Erritzoe, D., Williams, T. M., Stone, J. M., Evans, J., Sharp, D. J., Feilding, A., Wise, R. G., & Nutt, D. J. (2013) · Schizophrenia Bulletin · doi:10.1093/schbul/sbs117 · Cited by 256 · see citing works
Keller, C. J., Bickel, S., Honey, C. J., Groppe, D. M., Entz, L., Craddock, R. C., Lado, F. A., Kelly, C., Milham, M., & Mehta, A. D. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.4837-12.2013 · Cited by 245 · see citing works
Increased frontal and paralimbic activation following ayahuasca, the pan-amazonian inebriant
Riba, J., Romero, S., Grasa, E., Mena, E., Carrió, I., & Barbanoj, M. J. (2006) · Psychopharmacology · doi:10.1007/s00213-006-0358-7 · Cited by 241 · see citing works
Seeing with the eyes shut: neural basis of enhanced imagery following ayahuasca ingestion.
de Araujo, D. B., Ribeiro, S., Cecchi, G. A., Carvalho, F. M., Sanchez, T. A., Pinto, J. P., de Martinis, B. S., Crippa, J. A., Hallak, J. E. C., & Santos, A. C. (2012) · Human Brain Mapping · doi:10.1002/hbm.21381 · Cited by 239 · see citing works
Self-citationFunctional abnormalities of the default network during self- and other-reflection in autism
Kennedy, D. P., & Courchesne, E. (2008) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsn011 · Cited by 230 · see citing works
Brain functional integration decreases during propofol-induced loss of consciousness
Schrouff, J., Perlbarg, V., Boly, M., Marrelec, G., Boveroux, P., Vanhaudenhuyse, A., Bruno, M., Laureys, S., Phillips, C. L. M., Pélégrini‐Issac, M., et al. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2011.04.020 · Cited by 228 · see citing works
Hypnotic induction decreases anterior default mode activity
McGeown, W. J., Mazzoni, G., Venneri, A., & Kirsch, I. (2009) · Consciousness and Cognition · doi:10.1016/j.concog.2009.09.001 · Cited by 195 · see citing works
Gentili, C., Ricciardi, E., Gobbini, M. I., Santarelli, M. F., Haxby, J. V., Pietrini, P., & Guazzelli, M. (2009) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2009.02.002 · Cited by 186 · see citing works
Influence of meditation on anti-correlated networks in the brain
Josipovic, Z., Dinstein, I., Weber, J., & Heeger, D. J. (2012) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2011.00183 · Cited by 160 · see citing works
The Antipodes of the Mind: Charting the Phenomenology of the Ayahuasca Experience
Shanon, B. (2003) · Cited by 147 · see citing works
Pharmacology of ayahuasca administered in two repeated doses
dos Santos, R. G., Grasa, E., Valle, M., Ballester, M. R., Bouso, J. C., Nomdedéu, J. F., Homs, R., Barbanoj, M. J., & Riba, J. (2012) · Psychopharmacology · doi:10.1007/s00213-011-2434-x · Cited by 141 · see citing works
The Antipodes of the Mind: Charting the Phenomenology of the Ayahuasca Experience
Roberts, T. B. (2003) · Anthropology of Consciousness · doi:10.1525/ac.2003.14.1.75 · Cited by 120 · see citing works
When the Endogenous Hallucinogenic Trace AmineN,N-Dimethyltryptamine Meets the Sigma-1 Receptor
Su, T., Hayashi, T., & Vaupel, D. B. (2009) · Science Signaling · doi:10.1126/scisignal.261pe12 · Cited by 110 · see citing works
Bouso, J. C., Fábregas, J. M., Antonijoan, R. M., Rodríguez-Fornells, A., & Riba, J. (2013) · Psychopharmacology · doi:10.1007/s00213-013-3167-9 · Cited by 96 · see citing works
Default Mode Network in the Effects of Δ9-Tetrahydrocannabinol (THC) on Human Executive Function
Bossong, M. G., Jansma, J. M., van Hell, H. H., Jager, G., Kahn, R. S., & Ramsey, N. F. (2013) · PLoS ONE · doi:10.1371/journal.pone.0070074 · Cited by 73 · see citing works
On Mind Wandering, Attention, Brain Networks, and Meditation
Sood, A., & Jones, D. T. (2013) · EXPLORE · doi:10.1016/j.explore.2013.02.005 · Cited by 68 · see citing works
Donaldson, C. D., Nakawaki, B., & Crano, W. (2015) · Addictive Behaviours · doi:10.1016/j.addbeh.2015.01.022 · Cited by 61 · see citing works
Brain structural and functional correlates of resilience to Bipolar Disorder
Frangou, S. (2012) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2011.00184 · Cited by 58 · see citing works
Extraversion and anterior vs. posterior DMN activity during self-referential thoughts
Knyazev, G. G. (2013) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2012.00348 · Cited by 45 · see citing works
Psychedelics and Religious Experience
Watts, A. (1968) · California Law Review · doi:10.2307/3479497 · Cited by 27 · see citing works
Psychedelics and Religious Experience
Watts, A. W. (1968) · bepress Legal Repository · doi:10.15779/z38m467 · Cited by 24 · see citing works
MARTIN, F. H. (1934) · Annals of Surgery · doi:10.1097/00000658-193401000-00027 · Cited by 20 · see citing works
Flowering Newsletter bibliography for 2006
(2007) · Journal of Experimental Botany · doi:10.1093/jxb/erm028 · Cited by 3 · see citing works
(2014) · Institutional Repository University of Antioquia (University of Antioquia) · doi:10.1371/journal.pone
Flagged first, then by citations
Cited by
Sorted by citations
Nichols, D. E. (2016) · Pharmacological Reviews · doi:10.1124/pr.115.011478 · Cited by 1,762 · see citing works
Neural correlates of the LSD experience revealed by multimodal neuroimaging
Carhart-Harris, R. L., Muthukumaraswamy, S., Roseman, L., Kaelen, M., Droog, W., Murphy, K., Tagliazucchi, E., Schenberg, E. E., Nest, T., Orban, C., et al. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1518377113 · Cited by 859 · see citing works
Palhano-Fontes, F., Barreto, D., Onias, H., Andrade, K. C., Novaes, M. M., Pessoa, J. A., Mota-Rolim, S. A., Osório, F. L., Sanches, R., dos Santos, R. G., et al. (2019) · Psychological Medicine · doi:10.1017/s0033291718001356 · Cited by 852 · see citing works
Self-citationThe Therapeutic Potential of Psychedelic Drugs: Past, Present, and Future
Carhart-Harris, R. L., & Goodwin, G. M. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2017.84 · Cited by 706 · see citing works
Psychedelic drugs: neurobiology and potential for treatment of psychiatric disorders
Vollenweider, F. X., & Preller, K. H. (2020) · Nature Reviews Neuroscience · doi:10.1038/s41583-020-0367-2 · Cited by 570 · see citing works
Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms
Carhart-Harris, R. L., Roseman, L., Bolstridge, M., Demetriou, L., Pannekoek, J. N., Wall, M. B., Tanner, M., Kaelen, M., McGonigle, J., Murphy, K., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-13282-7 · Cited by 587 · see citing works
The entropic brain - revisited
Carhart-Harris, R. L. (2018) · Neuropharmacology · doi:10.1016/j.neuropharm.2018.03.010 · Cited by 522 · see citing works
Increased global functional connectivity correlates with LSD-induced ego dissolution
Tagliazucchi, E., Roseman, L., Kaelen, M., Orban, C., Muthukumaraswamy, S. D., Murphy, K., Laufs, H., Leech, R., McGonigle, J., Crossley, N., et al. (2016) · Current Biology · doi:10.1016/j.cub.2016.02.010 · Cited by 503 · see citing works
Johnson, M. W., Hendricks, P. S., Barrett, F. S., & Griffiths, R. R. (2019) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2018.11.010 · Cited by 506 · see citing works
Ego-dissolution and psychedelics: validation of the ego-dissolution inventory (EDI).
Nour, M. M., Evans, L., Nutt, D., & Carhart-Harris, R. L. (2016) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2016.00269 · Cited by 470 · see citing works
Sanches, R. F., de Lima Osório, F., dos Santos, R. G., Macedo, L. R. H., Maia-de-Oliveira, J. P., Wichert-Ana, L., de Araujo, D. B., Riba, J., Crippa, J. A. S., & Hallak, J. E. C. (2016) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0000000000000436 · Cited by 466 · see citing works
Self-citationPsychedelics, meditation, and self-consciousness
Millière, R., Carhart-Harris, R. L., Roseman, L., Trautwein, F.-M., & Berkovich-Ohana, A. (2018) · Frontiers in Psychology · doi:10.3389/fpsyg.2018.01475 · Cited by 390 · see citing works
Preller, K. H., Burt, J. B., Ji, J. L., Schleifer, C. H., Adkinson, B. D., Stämpfli, P., Seifritz, E., Repovs, G., Krystal, J. H., Murray, J. D., et al. (2018) · eLife · doi:10.7554/elife.35082 · Cited by 390 · see citing works
Emotions and brain function are altered up to one month after a single high dose of psilocybin.
Barrett, F. S., Doss, M. K., Sepeda, N. D., Pekar, J. J., & Griffiths, R. R. (2020) · Scientific Reports · doi:10.1038/s41598-020-59282-y · Cited by 375 · see citing works
Doss, M. K., Považan, M., Rosenberg, M. D., Sepeda, N. D., Davis, A. K., Finan, P. H., Smith, G. S., Pekar, J. J., Barker, P. B., Griffiths, R. R., et al. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01706-y · Cited by 356 · see citing works
Psychiatry & the psychedelic drugs. Past, present & future
Rucker, J. J. H., Iliff, J., & Nutt, D. J. (2018) · Neuropharmacology · doi:10.1016/j.neuropharm.2017.12.040 · Cited by 343 · see citing works
dos Santos, R. G., Osório, F. L., Crippa, J. A. S., Riba, J., Zuardi, A. W., & Hallak, J. E. C. (2016) · Therapeutic Advances in Psychopharmacology · doi:10.1177/2045125316638008 · Cited by 306 · see citing works
Self-citationSelf unbound: ego dissolution in psychedelic experience
Letheby, C., & Gerrans, P. (2017) · Neuroscience of Consciousness · doi:10.1093/nc/nix016 · Cited by 293 · see citing works
“Palhano-Fontes et al. (2015) reported decreased BOLD signal in DMN nodes including the MPFC and PCC during ayahuasca intoxication.”
BackgroundCessation and reduction in alcohol consumption and misuse after psychedelic use
Garcia‐Romeu, A., Davis, A. K., Erowid, F., Erowid, E., Griffiths, R. R., & Johnson, M. W. (2019) · Journal of Psychopharmacology · doi:10.1177/0269881119845793 · Cited by 287 · see citing works
Psilocybin desynchronizes the human brain
Siegel, J. S., Subramanian, S., Perry, D., Kay, B. P., Gordon, E. M., Laumann, T. O., Reneau, T. R., Metcalf, N. V., Chacko, R. V., Gratton, C., et al. (2024) · Nature · doi:10.1038/s41586-024-07624-5 · Cited by 290 · see citing works
Mason, N. L., Kuypers, K. P. C., Müller, F., Reckweg, J., Tse, D. H. Y., Toennes, S. W., Hutten, N. R. P. W., Jansen, J. F. A., Stiers, P., Feilding, A., et al. (2020) · Neuropsychopharmacology · doi:10.1038/s41386-020-0718-8 · Cited by 258 · see citing works
Gregorio, D. D., Aguilar‐Valles, A., Preller, K. H., Heifets, B. D., Hibicke, M., Mitchell, J., & Gobbi, G. (2020) · Journal of Neuroscience · doi:10.1523/jneurosci.1659-20.2020 · Cited by 261 · see citing works
Classical psychedelics for the treatment of depression and anxiety: A systematic review
Muttoni, S., Ardissino, M., & John, C. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.07.076 · Cited by 256 · see citing works
Smigielski, L., Scheidegger, M., Kometer, M., & Vollenweider, F. X. (2019) · NeuroImage · doi:10.1016/j.neuroimage.2019.04.009 · Cited by 248 · see citing works
Default Mode Network Modulation by Psychedelics: A Systematic Review
Gattuso, J. J., Perkins, D., Ruffell, S., Lawrence, A. J., Hoyer, D., Jacobson, L. H., Timmermann, C., Castle, D., Rossell, S. L., Downey, L. A., et al. (2023) · International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyac074 · Cited by 256 · see citing works
The therapeutic potentials of Ayahuasca: possible effects against various diseases of civilization
Frecska, E., Bokor, P., & Winkelman, M. (2016) · Frontiers in Pharmacology · doi:10.3389/fphar.2016.00035 · Cited by 242 · see citing works
Psychedelics in Psychiatry: Neuroplastic, Immunomodulatory, and Neurotransmitter Mechanisms
Inserra, A., De Gregorio, D., & Gobbi, G. (2021) · Pharmacological Reviews · doi:10.1124/pharmrev.120.000056 · Cited by 232 · see citing works
Atasoy, S., Roseman, L., Kaelen, M., Kringelbach, M. L., Deco, G., & Carhart-Harris, R. L. (2017) · Scientific Reports · doi:10.1038/s41598-017-17546-0 · Cited by 214 · see citing works
SANTOS, R. G. D., Bouso, J. C., Alcázar‐Córcoles, M. Á., & Hallak, J. E. C. (2018) · Expert Review of Clinical Pharmacology · doi:10.1080/17512433.2018.1511424 · Cited by 228 · see citing works
Self-citationHuman brain effects of DMT assessed via EEG-fMRI
Timmermann, C., Roseman, L., Haridas, S., Rosas, F. E., Luan, L., Kettner, H., Martell, J., Erritzøe, D., Tagliazucchi, E., Pallavicini, C., et al. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2218949120 · Cited by 215 · see citing works
Uthaug, M. V., van Oorsouw, K., Kuypers, K. P. C., van Boxtel, M., Broers, N. J., Mason, N. L., Toennes, S. W., Riba, J., & Ramaekers, J. G. (2018) · Psychopharmacology · doi:10.1007/s00213-018-4988-3 · Cited by 212 · see citing works
Sampedro, F., de la Fuente Revenga, M., Valle, M., Roberto, N., Domínguez-Clavé, E., Elices, M., Luna, L. E., Crippa, J. A. S., Hallak, J. E. C., de Araujo, D. B., et al. (2017) · International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyx036 · Cited by 200 · see citing works
Self-citationClinical applications of hallucinogens: a review
Garcia-Romeu, A., Kersgaard, B., & Addy, P. H. (2016) · Experimental and Clinical Psychopharmacology · doi:10.1037/pha0000084 · Cited by 201 · see citing works
Ayahuasca enhances creative divergent thinking while decreasing conventional convergent thinking
Kuypers, K. P. C., Riba, J., de la Fuente Revenga, M., Barker, S., Theunissen, E. L., & Ramaekers, J. G. (2016) · Psychopharmacology · doi:10.1007/s00213-016-4377-8 · Cited by 201 · see citing works
Models of psychedelic drug action: modulation of cortical-subcortical circuits
Doss, M. K., Madden, M. B., Gaddis, A., Nebel, M. B., Griffiths, R. R., Mathur, B. N., & Barrett, F. S. (2021) · Brain · doi:10.1093/brain/awab406 · Cited by 198 · see citing works
Consciousness and complexity: a consilience of evidence
Sarasso, S., Casali, A. G., Casarotto, S., Rosanova, M., Sinigaglia, C., & Massimini, M. (2021) · Neuroscience of Consciousness · doi:10.1093/nc/niab023 · Cited by 171 · see citing works
Garcia‐Romeu, A., & Richards, W. A. (2018) · International Review of Psychiatry · doi:10.1080/09540261.2018.1486289 · Cited by 191 · see citing works
Unifying Theories of Psychedelic Drug Effects
Swanson, L. R. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00172 · Cited by 181 · see citing works
Brain mechanisms in religion and spirituality: An integrative predictive processing framework
van Elk, M., & Aleman, A. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.12.031 · Cited by 180 · see citing works
The cultural evolution of shamanism
Singh, M. (2017) · Behavioral and Brain Sciences · doi:10.1017/s0140525x17001893 · Cited by 175 · see citing works
Hamill, J., Hallak, J. E. C., Dursun, S. M., & Baker, G. B. (2018) · Current Neuropharmacology · doi:10.2174/1570159x16666180125095902 · Cited by 182 · see citing works
Self-citationNeuroimaging the consciousness of self: Review, and conceptual-methodological framework
Frewen, P., Schroeter, M. L., Riva, G., Cipresso, P., Fairfield, B., Padulo, C., Kemp, A. H., Palaniyappan, L. K., Owolabi, M. O., Kusi‐Mensah, K., et al. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.01.023 · Cited by 177 · see citing works
Altered network hub connectivity after acute LSD administration
Müller, F., Dolder, P. C., Schmidt, A., Liechti, M. E., & Borgwardt, S. (2018) · NeuroImage: Clinical · doi:10.1016/j.nicl.2018.03.005 · Cited by 174 · see citing works
Ayahuasca, dimethyltryptamine, and psychosis: a systematic review of human studies
SANTOS, R. G. D., Bouso, J. C., & Hallak, J. E. C. (2017) · Therapeutic Advances in Psychopharmacology · doi:10.1177/2045125316689030 · Cited by 168 · see citing works
Self-citationSANTOS, R. G. D., Osório, F. D. L., Crippa, J. A. S., & Hallak, J. E. C. (2016) · Brazilian Journal of Psychiatry · doi:10.1590/1516-4446-2015-1701 · Cited by 163 · see citing works
Self-citationPsychedelic Drugs in Biomedicine
Kyzar, E. J., Nichols, C. D., Gainetdinov, R. R., Nichols, D. E., & Kalueff, A. V. (2017) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2017.08.003 · Cited by 155 · see citing works
Millière, R. (2017) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2017.00245 · Cited by 206 · see citing works
Viol, A., Palhano-Fontes, F., Onias, H., de Araújo, D. B., & Viswanathan, G. M. (2017) · Scientific Reports · doi:10.1038/s41598-017-06854-0 · Cited by 136 · see citing works
Self-citationAyahuasca’s ‘afterglow’: improved mindfulness and cognitive flexibility in ayahuasca drinkers
Murphy-Beiner, A., & Soar, K. (2020) · Psychopharmacology · doi:10.1007/s00213-019-05445-3 · Cited by 135 · see citing works
Carhart-Harris, R. L. (2018) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000000467 · Cited by 133 · see citing works
Harmonic brain modes: a unifying framework for linking space and time in brain dynamics
Atasoy, S., Deco, G., Kringelbach, M. L., & Pearson, J. (2018) · The Neuroscientist · doi:10.1177/1073858417728032 · Cited by 124 · see citing works
Spontaneous and deliberate creative cognition during and after psilocybin exposure
Mason, N. L., Kuypers, K. P. C., Reckweg, J. T., Müller, F., Tse, D. H. Y., Rios, B. D., Toennes, S. W., Stiers, P. L. J., Feilding, A., & Ramaekers, J. G. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01335-5 · Cited by 129 · see citing works
An online survey of tobacco smoking cessation associated with naturalistic psychedelic use
Johnson, M. W., Garcia‐Romeu, A., Johnson, P. S., & Griffiths, R. R. (2017) · Journal of Psychopharmacology · doi:10.1177/0269881116684335 · Cited by 129 · see citing works
Changes in inflammatory biomarkers are related to the antidepressant effects of Ayahuasca
Galvão-Coelho, N. L., de Menezes Galvão, A. C., de Almeida, R. N., Palhano-Fontes, F., Campos Braga, I., Lobão Soares, B., Maia-de-Oliveira, J. P., Perkins, D., Sarris, J., & de Araujo, D. B. (2020) · Journal of Psychopharmacology · doi:10.1177/0269881120936486 · Cited by 128 · see citing works
Self-citationUpdating the dynamic framework of thought: Creativity and psychedelics
Girn, M., Mills, C., Roseman, L., Carhart-Harris, R. L., & Kalina Christoff, A. (2020) · NeuroImage · doi:10.1016/j.neuroimage.2020.116726 · Cited by 127 · see citing works
dos Santos, R. G., Balthazar, F. M., Bouso, J. C., & Hallak, J. E. (2016) · Journal of Psychopharmacology · doi:10.1177/0269881116652578 · Cited by 125 · see citing works
van Elk, M., Gomez, M. A. A., van der Zwaag, W., van Schie, H. T., & Sauter, D. A. (2019) · Human Brain Mapping · doi:10.1002/hbm.24616 · Cited by 124 · see citing works
Speth, J., Speth, C., Kaelen, M., Schloerscheidt, A. M., Feilding, A., Nutt, D., & Carhart-Harris, R. (2016) · Journal of Psychopharmacology · doi:10.1177/0269881116628430 · Cited by 118 · see citing works
Subacute effects of the psychedelic ayahuasca on the salience and default mode networks
Pasquini, L., Palhano-Fontes, F., & de Araújo, D. B. (2020) · Journal of Psychopharmacology · doi:10.1177/0269881120909409 · Cited by 115 · see citing works
Self-citationAdverse effects of ayahuasca: Results from the Global Ayahuasca Survey
Bouso, J. C., Andión, Ó., Sarris, J. J., Scheidegger, M., Tófoli, L. F., Opaleye, E. S., Schubert, V., & Perkins, D. (2022) · PLOS Global Public Health · doi:10.1371/journal.pgph.0000438 · Cited by 118 · see citing works
Self-citationEfficacy of psychedelic treatments on depressive symptoms: A meta-analysis
Roméo, B., Karila, L., Martelli, C., & Benyamina, A. (2020) · Journal of Psychopharmacology · doi:10.1177/0269881120919957 · Cited by 114 · see citing works
dos Santos, R. G., & Hallak, J. E. C. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.12.001 · Cited by 111 · see citing works
Self-citationUthaug, M. V., Mason, N. L., Toennes, S. W., Reckweg, J. T., de Sousa Fernandes Perna, E. B., Kuypers, K. P. C., van Oorsouw, K., Riba, J., & Ramaekers, J. G. (2021) · Psychopharmacology · doi:10.1007/s00213-021-05817-8 · Cited by 112 · see citing works
Reckweg, J. T., Uthaug, M. V., Szabó, A., Davis, A. K., Lancelotta, R., Mason, N. L., & Ramaekers, J. G. (2022) · Journal of Neurochemistry · doi:10.1111/jnc.15587 · Cited by 111 · see citing works
Jiménez-Garrido, D. F., Gómez-Sousa, M., Ona, G., Dos Santos, R. G., Hallak, J. E. C., Alcázar-Córcoles, M. Á., & Bouso, J. C. (2020) · Scientific Reports · doi:10.1038/s41598-020-61169-x · Cited by 110 · see citing works
Self-citationClassic Psychedelic Drugs: Update on Biological Mechanisms
Vollenweider, F. X., & Smallridge, J. W. (2022) · Pharmacopsychiatry · doi:10.1055/a-1721-2914 · Cited by 112 · see citing works
The Mechanisms of Psychedelic Visionary Experiences: Hypotheses from Evolutionary Psychology
Winkelman, M. (2017) · Frontiers in Neuroscience · doi:10.3389/fnins.2017.00539 · Cited by 109 · see citing works
McCulloch, D. E.-W., Knudsen, G. M., Barrett, F. S., Doss, M. K., Carhart-Harris, R. L., Rosas, F. E., Deco, G., Kringelbach, M. L., Preller, K. H., Ramaekers, J. G., et al. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104689 · Cited by 108 · see citing works
Kadriu, B., Greenwald, M., Henter, I. D., Gilbert, J. R., Kraus, C., Park, L. T., & Zarate, C. A. (2021) · International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyaa087 · Cited by 99 · see citing works
An affective neuroscience model of boosting resilience in adults
Tabibnia, G. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.05.005 · Cited by 109 · see citing works
Ayahuasca’s entwined efficacy: An ethnographic study of ritual healing from ‘addiction’
Talin, P., & Sanabria, E. (2017) · International Journal of Drug Policy · doi:10.1016/j.drugpo.2017.02.017 · Cited by 103 · see citing works
Serotonergic psychedelics temporarily modify information transfer in humans.
Alonso, J. F., Romero, S., Mañanas, M. À., & Riba, J. (2015) · International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyv039 · Cited by 101 · see citing works
Classical hallucinogens and neuroimaging: A systematic review of human studies
dos Santos, R. G., Osório, F. L., Crippa, J. A. S., & Hallak, J. E. C. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.10.026 · Cited by 107 · see citing works
Self-citationThe acute effects of classic psychedelics on memory in humans
Healy, C. J. (2021) · Psychopharmacology · doi:10.1007/s00213-020-05756-w · Cited by 95 · see citing works
Nunes, A. A., SANTOS, R. G. D., Osório, F. D. L., Sanches, R. F., Crippa, J. A. S., & Hallak, J. E. C. (2016) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2016.1188225 · Cited by 91 · see citing works
Self-citationInserra, A. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00330 · Cited by 91 · see citing works
Ayahuasca Improves Self-perception of Speech Performance in Subjects With Social Anxiety Disorder
SANTOS, R. G. D., Osório, F. D. L., Rocha, J. M., Rossi, G. N., Bouso, J. C., Rodrigues, L. S., Silveira, G. D. O., Yonamine, M., & Hallak, J. E. C. (2021) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0000000000001428 · Cited by 91 · see citing works
Self-citationKiraga, M. K., Mason, N. L., Uthaug, M. V., van Oorsouw, K. I. M., Toennes, S. W., Ramaekers, J. G., & Kuypers, K. P. C. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.721537 · Cited by 85 · see citing works
Neural Mechanisms and Psychology of Psychedelic Ego Dissolution
Stoliker, D., Egan, G. F., Friston, K. J., & Razi, A. (2022) · Pharmacological Reviews · doi:10.1124/pharmrev.121.000508 · Cited by 89 · see citing works
Combining Psychedelic and Mindfulness Interventions: Synergies to Inform Clinical Practice
Payne, J. E., Chambers, R., & Liknaitzky, P. (2021) · ACS Pharmacology & Translational Science · doi:10.1021/acsptsci.1c00034 · Cited by 78 · see citing works
The Psychedelic Future of Post-Traumatic Stress Disorder Treatment
Zaretsky, T. G., Jagodnik, K. M., Barsic, R., Antonio, J. H., Bonanno, P. A., MacLeod, C., Pierce, C., Carney, H., Morrison, M. T., Saylor, C. F., et al. (2024) · Current Neuropharmacology · doi:10.2174/1570159x22666231027111147 · Cited by 85 · see citing works
More Realistic Forecasting of Future Life Events After Psilocybin for Treatment-Resistant Depression
Lyons, T., & Carhart-Harris, R. L. (2018) · Frontiers in Psychology · doi:10.3389/fpsyg.2018.01721 · Cited by 77 · see citing works
A review on research and evaluation methods for investigating self-transcendence
Kitson, A., Chirico, A., Gaggioli, A., & Riecke, B. E. (2020) · Frontiers in Psychology · doi:10.3389/fpsyg.2020.547687 · Cited by 76 · see citing works
Therapeutic potential of ayahuasca in grief: a prospective, observational study
González, D., Cantillo, J., Pérez, I., Farré, M., Feilding, A., Obiols, J. E., & Bouso, J. C. (2020) · Psychopharmacology · doi:10.1007/s00213-019-05446-2 · Cited by 75 · see citing works
A complex systems perspective on psychedelic brain action
Girn, M., Rosas, F. E., Daws, R. E., Gallen, C. L., Gazzaley, A. H., & Carhart-Harris, R. L. (2023) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2023.01.003 · Cited by 72 · see citing works
Neural and subjective effects of inhaled N,N-dimethyltryptamine in natural settings
Pallavicini, C., Cavanna, F., Zamberlán, F., de la Fuente, L. A., Ilksoy, Y. A., Perl, Y. S., Arias, M., Romero, C., Carhart-Harris, R. L., Timmermann, C., et al. (2021) · Journal of Psychopharmacology · doi:10.1177/0269881120981384 · Cited by 83 · see citing works
Ruffell, S., Netzband, N., Tsang, W., Davies, M., Inserra, A., Butler, M., Rucker, J., Tófoli, L. F., Dempster, E. L., Young, A. H., et al. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.687615 · Cited by 74 · see citing works
DMT alters cortical travelling waves
Alamia, A., Timmermann, C., Nutt, D. J., VanRullen, R., & Carhart-Harris, R. L. (2020) · eLife · doi:10.7554/elife.59784 · Cited by 97 · see citing works
Psychedelic therapy's transdiagnostic effects: A research domain criteria (RDoC) perspective
Kelly, J. R., Gillan, C. M., Prenderville, J., Kelly, C., Harkin, A., Clarke, G., & O'Keane, V. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.800072 · Cited by 69 · see citing works
Content-free awareness: EEG-fcMRI correlates of consciousness as such in an expert meditator
Winter, U., LeVan, P., Borghardt, T. L., Akin, B., Wittmann, M., Leyens, Y., & Schmidt, S. (2020) · Frontiers in Psychology · doi:10.3389/fpsyg.2019.03064 · Cited by 63 · see citing works
Mertens, L. J., & Preller, K. H. (2021) · Pharmacopsychiatry · doi:10.1055/a-1341-1907 · Cited by 65 · see citing works
Uthaug, M. V., Davis, A. K., Haas, T. F., Davis, D. D., Dolan, S. B., Lancelotta, R., Timmermann, C., & Ramaekers, J. G. (2021) · Journal of Psychopharmacology · doi:10.1177/02698811211013583 · Cited by 65 · see citing works
A unified model of ketamine’s dissociative and psychedelic properties
Marguilho, M., Figueiredo, I., & Castro-Rodrigues, P. (2022) · Journal of Psychopharmacology · doi:10.1177/02698811221140011 · Cited by 65 · see citing works
Atasoy, S., Vohryzek, J., Deco, G., Carhart-Harris, R. L., & Kringelbach, M. L. (2018) · Progress in brain research · doi:10.1016/bs.pbr.2018.08.009 · Cited by 57 · see citing works
SANTOS, R. G. D., Bouso, J. C., Rocha, J. M., Rossi, G. N., & Hallak, J. E. C. (2021) · Risk Management and Healthcare Policy · doi:10.2147/rmhp.s300656 · Cited by 60 · see citing works
Self-citationNeuropharmacological modulation of the aberrant bodily self through psychedelics
Ho, J. T., Preller, K. H., & Lenggenhager, B. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.12.006 · Cited by 60 · see citing works
Spectral signatures of serotonergic psychedelics and glutamatergic dissociatives
Pallavicini, C., Vilas, M. G., Villarreal, M. F., Zamberlán, F., Muthukumaraswamy, S. D., Nutt, D., Carhart-Harris, R. L., & Tagliazucchi, E. (2019) · NeuroImage · doi:10.1016/j.neuroimage.2019.06.053 · Cited by 55 · see citing works
A Psychoanalytic Perspective on Psychedelic Experience
Guss, J. R. (2022) · Psychoanalytic Dialogues · doi:10.1080/10481885.2022.2106140 · Cited by 58 · see citing works
Modulatory effects of ayahuasca on personality structure in a traditional framework
Netzband, N., Ruffell, S., Linton, S., Tsang, W., & Wolff, T. J. (2020) · Psychopharmacology · doi:10.1007/s00213-020-05601-0 · Cited by 58 · see citing works
Elsey, J. W. B. (2017) · Drug Science Policy and Law · doi:10.1177/2050324517723232 · Cited by 57 · see citing works
- Authors
- Palhano-Fontes, F., Andrade, K. C., Tofoli, L. F., Santos, A. C., Crippa, J. A. S., Hallak, J. E. C., Ribeiro, S., & de Araujo, D. B.
- Affiliations
- Universidade Federal do Rio Grande do Norte (BR)
- Universidade de São Paulo (BR)
- Venue
- PLOS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2015-02-18
- Volume
- 10
- Issue
- 2
- Pages
- e0118143
- ISSN
- 1932-6203 (ISSN-L)
- PMC
- PMC4334486
- OpenAlex
- W2093477837
- Cited by
- 454
- References
- 60
- Citations by year
- 2026: 34 · 2025: 41 · 2024: 45 · 2023: 61 · 2022: 54 · 2021: 49 · 2020: 40 · 2019: 47 · 2018: 31 · 2017: 25 · 2016: 20 · 2015: 6
- FWCI
- 33.90
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- PLoS ONE (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) (publishedVersion, other-oa)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (publishedVersion, other-oa)
- Americanae (AECID Library) (submittedVersion, other-oa)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Figshare (submittedVersion, cc-by)
- Funders
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Financiadora de Estudos e Projetos
- Topics
- Social Sciences › Psychology › Clinical Psychology › Psychedelics and Drug Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Pain Management and Placebo Effect
- Keywords
- ayahuasca, default mode network, task-positive network, altered states of consciousness, psychedelic effects, posterior cingulate cortex, precuneus, medial prefrontal cortex, functional connectivity, self-reflection, psilocybin, meditation, sleep
- MeSH terms
- Adult, Consciousness Disorders, Female, Gyrus Cinguli, Hallucinogens, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Psilocybin, Prefrontal Cortex, Banisteriopsis, Young Adult, Connectome
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
